Ðe esia gbɔe wò ŋutilã ƒe veve kple ŋutigbalẽ ƒe tɔtrɔ tsona? Mina míaƒo nu tso Eosinophilia-Myalgia Syndrome (EMS) ŋu!

Ɣeaɖewoɣi la, esesẽna be míase dɔléle siwo míexɔna gɔme, alo? Kasia, míesea veve le míaƒe ŋutilã me, nu suesuesuewo dzena le míaƒe ŋutigbalẽ ŋu, eye gbɔgbɔ sesẽna vie. Egbea míele nu ƒom tso nɔnɔme aɖe si mebɔ o gake wòtsia dzimaɖi si vaa dzesi siawo siwo dze abe ɖe womedo ƒome kple wo nɔewo o ene la ŋu. Woyɔa esia be `Eosinophilia-Myalgia Dɔléle` (EMS). Togbɔ be ŋkɔa adze abe ɖe wòdidi vie ene hã la, mina míase egɔme bɔbɔe.

Nukae nye Eosinophilia-Myalgia Dɔléle (EMS)?

Kpuie ko la, `Eosinophilia-Myalgia Syndrome` (EMS) nye dɔléle si mebɔ o si gblẽa nu le wò lãmekawo, ŋutigbalẽ, kple lãkusiwo ŋu . Nusi dzɔna le esia me enye be ʋumenugbagbevi ɣi ƒomevi aɖe si woyɔna be `eosinophils` , si le míaƒe ʋu me la ƒoa ƒu wògbɔa eme eye wòdea míaƒe lãkusiwo me. Bu eŋu ale, `eosinophils` siawo le abe míaƒe ŋutilã ƒe dedienɔnɔdzikpɔlawo ene. Gake ne asrafo siawo va sɔ gbɔ akpa la, wodzea kuxiwo hehe vɛ na mía ŋutɔwo míaƒe ŋutilã.

Nɔnɔme sia ate ŋu ana lãmekawo nase veve vevie (myalgia) , ŋutigbalẽ ƒe ʋuʋu alo tɔtrɔ bubuwo, eye gbɔgbɔ nasesẽ na ame . Ɣeaɖewoɣi la, dzesi siawo ate ŋu ade ame ƒe agbe afɔku me alo ana ame nase veve vevie si wɔnɛ be gbesiagbedɔwo wɔwɔ sesẽna.

Nɔnɔme sia si woyɔna be `EMS` nye nɔnɔme bubu si woyɔna be `eosinophilia` ƒe ƒomevi sue aɖe. `Eosinophilia` nye `eosinophils` ƒe dzidziɖedzi le ʋu alo lãkusiwo me ko.

Nusi gbɔ EMS tsona wue nye kpeɖeŋutɔ siwo me atike siwo woyɔna be L-tryptophan alo 5-hydroxytryptophan (5-HTP) le zazã, abe alesi ɖewohĩ èsee ene. Ke hã, wokpɔe hã be ame aɖewo ate ŋu axɔ dɔlélea ne womezã esiawo o.

Aleke wòdzɔe be Eosinophilia-Myalgia Syndrome va zu dɔvɔ̃?

Ŋutinya sia do xoxo vie. Le ƒe 1989 me la, kasia dɔléle yeye aɖe do le Amerika. Numekulawo tsɔ ŋkɔ nɛ be `Eosinophilia-Myalgia Syndrome`. Ɣemaɣi la, ekaka abe dɔvɔ̃ ene. Ame siwo dze dɔ alea ƒe akpa gãtɔ nye amesiwo zã kpeɖeŋutɔ siwo me `L-tryptophan` si wowɔ kple asi le. Esia na `eosinophils` ƒo ƒu ɖe woƒe ʋu me, si na lãmekawo nɔ veve sem. Wogblɔ be ame siwo ade 37 ye ku ɣemaɣi.

Le nudzɔdzɔ sia megbe la, United States ƒe Nuɖuɖu Kple Atike Ŋuti Dɔwɔƒe (FDA) ɖe atike gbogbo aɖewo siwo me L-tryptophan le ɖa le asi me. Le ema megbe la, EMS dɔlékui siwo ŋu woka nya ta le ƒe xexlẽme dzi ɖe kpɔtɔ ŋutɔ.

Ke hã, emegbe kpeɖeŋutɔdɔwɔƒe mawo tsɔ eƒe `5-hydroxytryptophan (5-HTP)` si sɔ kplii ŋutɔ ɖɔ li `L-tryptophan`.Mete nya siwo wogblɔna la zazã. `Kpekpeɖeŋunanu` siawo fia nusiwo le abe alɔ̃dɔdɔ ƒe nyonyo, seselelãme ƒe nyonyo, kple bubuawo ene Ðewohĩ èkpɔ nusiawo be wonye nusiwo naa ŋutilã ƒe kamedede nyona ɖe edzi, ɖea lolo dzi kpɔtɔna, alo kpena ɖe ŋuwò nèdɔa alɔ̃. Eyata, ate ŋu adzɔ be `EMS` ate ŋu adzɔ abe esiawo ƒe nugbegblẽ le ame ŋu ene.

Nublanuitɔe la, esi wotrɔ se siwo ku ɖe nuɖuɖutikewo ŋu le United States le ƒe 1994 me ta la, nuɖuɖu kpeɖeŋutɔ siwo me L-tryptophan kple 5-HTP si wowɔ la gadze le asi me ake.

Ameka dzie nɔnɔme sia gblẽa nu le wu?

Le ƒe 1989 ƒe dɔvɔ̃a me la, ame akpa gãtɔ siwo kpe fu le `EMS` nɔnɔme sia me la nye amesiwo no `kpeɖeŋunuwo` siwo me `L-tryptophan` alo `5-HTP` le. Wogblɔ be le amesiawo dometɔ akpa gãtɔ nye nyɔnuwo .

Fifia la, nɔnɔme sia mebɔ kura o. Ke hã, abe alesi míegblɔe va yi ene la, woate ŋu akpɔ `EMS` dɔléle sia le amesiwo mezã atike siwo me `L-tryptophan` alo `5-HTP` le o hã ŋu.

Aleke gbegbee esia bɔe?

Akɔntabubu aɖeke meli si tututu ku ɖe alesi esia bɔe ŋu o. Wogblɔ be le ƒe 1989 ƒe dɔvɔ̃a me la, ame 5,000 va ɖo 10,000 ye woxɔ dɔa le United States ɖeɖe dzaa. Le ɣeyiɣi ma ke me la, wogblɔ be dɔlékuiawo hã tso dukɔwo abe Germany, Canada, kple United Kingdom ene me.

Nukae nye Eosinophilia-Myalgia Syndrome (EMS) ƒe dzesiwo?

EMS ƒe dzesiwo ate ŋu ato vovo tso ame ɖeka gbɔ yi bubu gbɔ, eye woƒe sesẽme hã ate ŋu ato vovo. Zi geɖe la, dzesi siawo dzea egɔme kpata. Dzesi siawo tsoa eosinophils ƒe ƒuƒoƒo ɖe ʋu kple lãkusiwo me gbɔ, si wɔnɛ be dɔdzẽ nɔa ame ŋu. Woate ŋu agblẽ nu le ŋutilã ƒe akpa vovovo geɖe ŋu.

Dzesi siwo wokpɔna zi geɖee nye:

• Ɖeɖiteameŋu .
• Asrã .
• Asiwo kple afɔwo ƒe vuvu (edema) .
• Asiwo kple afɔwo ƒe ʋuʋu .
• Esesẽna be woaɖo ŋku nu dzi alo atsɔ susu aɖo nu ŋu .
• Tɔtrɔ le seselelãme alo nuwɔna me .
• Aɖuɖɔtoe alo ʋuʋudedi .
• Dɔmetɔtrɔ .

Tsɔ kpe ɖe eŋu la, dzesi aɖewo koŋ ate ŋu adze le lãmekawo, ŋutigbalẽ, dzi, kple lãkusiwo hã me.

Dzesi siwo do ƒome kple lãmekawo kple ƒunukpeƒewo

Nu vevi siwo `EMS` wɔna dometɔ ɖekae nye ŋusẽkpɔɖeamedzi siwo gbɔna ɖe lãmekawo kple ƒunukpeƒewo dzi:

• Vevesese (`myalgia` alo `arthralgia`) : Esiae nye nu vevitɔ. Ŋutilã le veve sem, ƒunukpeƒewo hã le veve sem.
• Ŋutilã ƒe vevesese .
• Lãmetsiwo ƒe tete kpata kple woƒe ʋuʋu .
• Gbɔdzɔgbɔdzɔ .
• Lãmetsi alo ƒunukpeƒewo ƒe dɔmawɔmawɔ nyuie .

Vevesese si nèsena ate ŋu atso esi nu mesẽ o dzi va ɖo esi nu sẽ. Ate ŋu agblẽ ɖe edzi gɔ̃ hã le kwasiɖa ʋɛ aɖewo megbe.

Ŋutilã ƒe dzesiwo

Ŋutilã ƒe dzesiwo ate ŋu anɔ anyi abe ɣleti etɔ̃ va ɖo ade ene. Wo dometɔ aɖewoe nye:

• Ŋutilã ƒe ʋuʋudedi: Ðewohĩ abiã eye ʋuʋudedi le eŋu.
• Ŋutilã si le ʋuʋum .
• Ŋutilã ƒe akpa aɖewo siwo ƒe taɖa vuvu .
• Ŋutilã ƒe akpa siwo le ɣie : Woyɔa esia le atikewɔwɔ me be `eosinophilic fasciitis`.

Dzi kple lãkusi ƒe dzesiwo

Dzesi siwo gblẽa nu le lãkusiwo ŋu ate ŋu anɔ sue abe kɔdzidɔ ene, alo woate ŋu asẽ wu. Ne dzesi siwo gbɔna dometɔ aɖe le ŋuwò la, ele be nàyi xɔ si me wowɔa dɔ kpata le enumake :

• Yagbɔgbɔ sesẽ .
• Yagbɔgbɔ kpuie .
• Akɔtave .
• Dzi ƒe tsotso si mesɔ o (dzi ƒe tsotso si mewɔa dɔ nyuie o) .
• Dzi ƒe lãmeka ƒe dɔdzẽ (`myocarditis`) .

Vevietɔ: Ne gbɔgbɔ sesẽ na wò, akɔta le veve sem, alo dzi ƒe tsotso si mesɔ o la, mègafe o. Di atikewɔlawo ƒe aɖaŋuɖoɖo enumake.

Nukae hea Eosinophilia-Myalgia Syndrome (EMS) vɛ?

Esi woke ɖe EMS ŋu zi gbãtɔ le ƒe 1989 me la, wosusu be lãmesẽtike aɖe si me L-tryptophan si wowɔ le la gbɔe wòtso. L-tryptophan nye amino acid si le dzɔdzɔme nu si le nuɖuɖu aɖewo abe koklozi ene me. Gake ne wowɔe kple nusiwo wowɔ la, wokpɔe be enaa lãmekawo vea ame eye eosinophil ƒe agbɔsɔsɔ dzina ɖe edzi.

Togbɔ be atike siwo me L-tryptophan si wowɔ la gakpɔtɔ le asi me egbea hã la, nu bubu si wowɔ si sɔ kple L-tryptophan, si woyɔna be 5-HTP hã ate ŋu ahe EMS vɛ.

Gake EMS dɔnɔ aɖewo li siwo mezã naneke si me L-tryptophan alo 5-HTP le o. Esia fia be ate ŋu anye nu bubu siwo womenya o siwo gbɔ nɔnɔme sia tsona. Numekukuwo gale edzi yim kokoko.

Aleke wowɔna dea dzesi Eosinophilia-Myalgia Syndrome (EMS) ƒe dɔlélea?

Ðɔkta aɖe akpɔ EMS to wò dodokpɔ kple dodokpɔ siwo hiã wɔwɔ me. Nu vevi siwo ɖɔktaa adi le dodokpɔ sia me enye:

• Woalé ŋku ɖe ʋu si woɖe tso asiwò ŋu be eosinophils sɔ gbɔ hã.
• Mele ŋku lém ɖe eŋu be lãmekawo le veve sem na wò hã.

Woate ŋu awɔ ʋudodokpɔ bubu geɖe atsɔ anya dɔléle sia. Esiawo nye be woaɖe nɔnɔme bubu siwo me dzesi mawo tɔgbe le la ɖa. Ðɔktaa abia wò atikewɔwɔ ŋutinya kple kpeɖeŋutɔ ɖesiaɖe si nèzãna hã . Vevietɔ la, kpɔ egbɔ be `L-tryptophan` alo `5-HTP` le wo me.

Aleke wodaa Eosinophilia-Myalgia Syndrome (EMS) ƒe dɔléleae?

Atike aɖeke koŋ, ɖeka aɖeke meli na EMS o. Wò ɖɔkta awɔ atikewɔwɔ ƒe ɖoɖo si sɔ na wò be wòakpe ɖe ŋuwò nàkpɔ wò dzesiwo gbɔ. Esia ate ŋu alɔ atike siwo gbɔna ɖe eme:

• Atike siwo naa lãmekawo ɖea dzi ɖi .
• Vevesesenutsitikewo (`vevesesenutsitikewo`) .
• Atike siwo ɖea tsi bubu ɖa le ŋutilã me (diuretics) - ne vuvu le eŋu.
• Corticosteroids - Esiawo nye atike ƒomevi aɖe si wonana be woatsɔ aɖe dɔdzẽ dzi akpɔtɔ.

Nu vevitɔe nye be nàxlẽ kpeɖeŋutɔ ɖesiaɖe si nàno ƒe nuŋɔŋlɔ nyuie. Eye nàƒo nu tso nusiwo nàtsɔ awɔe ŋu na wò ɖɔkta. Ne `L-tryptophan` alo `5-HTP` le wo me la, ele be nàdzudzɔ wo nono enumake.

Le alesi wò lãmekawo ƒe vevesese nu sẽe nu la, wò ɖɔkta ate ŋu agblɔ na wò be nàɖe kamedede dzi akpɔtɔ be vevesesea nagagblẽ ɖe edzi o. Gake ame aɖewo kpɔe be kamedede bɔbɔe edziedzi le atikewɔwɔ me ate ŋu akpe ɖe ame ŋu be vevesese dzi naɖe akpɔtɔ.

Ðe woate ŋu axe mɔ ɖe Eosinophilia-Myalgia Syndrome (EMS) nua?

Esi womese nusiwo katã gbɔ EMS tsona gɔme bliboe o ta la, mɔ ɖeka aɖeke meli si dzi woato axe mɔ ɖe enu o. Gake àte ŋu aɖe wò afɔkua dzi akpɔtɔ ne èƒo asa na kpeɖeŋutɔ siwo me L-tryptophan alo 5-HTP le.

Ne Eosinophilia-Myalgia Syndrome (EMS) le ŋunye la, nukae wòle be makpɔ mɔ na?

Eosinophilia-Myalgia Syndrome (EMS) nye dɔléle si nɔa anyi didi , si fia be womate ŋu adae o eye wònɔa anyi didi. Wò dzesiwo ate ŋu ava eye woadzo le wò agbemeŋkekewo katã me. Togbɔ be dzesiawo de ame ƒe agbe afɔku me le ƒe 1989 ƒe dɔvɔ̃a me hã la, ne atikewɔmɔnuwo li egbea la, àte ŋu akpɔ wò dzesiawo gbɔ ahaxe mɔ ɖe kuxi sesẽwo nu. Numekulawo gale nu srɔ̃m tso eŋu nenye be nɔnɔme sia akpɔ ŋusẽ ɖe wò agbenɔƒe dzi.

Le ame aɖewo gome la, tsɔ kpe ɖe atikewo nono ŋu la, kamedede si mesẽ o wɔwɔ gbesiagbe ate ŋu akpe ɖe ame ŋu be woaɖe vevesese kple vevesese dzi akpɔtɔ. Wò ɖɔkta aƒo nu tso agbenɔnɔ ƒe tɔtrɔ siwo wòle be nàwɔ le wò atikewɔwɔ me ŋu na wò.

Ɣekaɣie wòle be makpɔ ɖɔkta?

Ne lãmekawo le veve sem vevie si nu sẽ ale gbegbe be màte ŋu awɔ wò gbesiagbedɔwo o, alo awɔ dɔ dzrowo gɔ̃ hã la, ele be nàkpɔ ɖɔkta godoo.

Azɔ hã, ne dzesi sesẽ siwo gbɔna dometɔ aɖe le ŋuwò si gblẽa nu le dzi alo lãkusi ŋu la, yi xɔ si me wowɔa dɔ kpata le enumake:

• Yagbɔgbɔ sesẽ .
• Akɔtave .
• Dzi ƒe tsotso ƒe kuxi aɖe .

Nya kawoe wòle be mabia nye ɖɔkta?

Ne èyi ɖɔkta gbɔ la, àte ŋu abia nya siawo tɔgbe:

• Ðe Eosinophilia-Myalgia Syndrome (EMS) alo dɔléle bubu si sɔ kplii le ŋunyea?
• Ðe `EMS` nɔnɔme sia tso kpeɖeŋutɔ siwo menona gbɔa?
• Nukawoe nye atike siawo ƒe nugbegblẽ le ame ŋu?
• Aleke gbegbee wòle be mawɔ kamededee?
• Ðe wòhiã be mawɔ tɔtrɔ aɖewo le nye agbenɔnɔ ŋua?

Mlɔeba la, ɖo ŋku esia dzi (Take-Home Message) .

Eosinophilia-Myalgia Syndrome (EMS) nye dɔléle si nɔa anyi didi si ate ŋu adze wò ŋutilã ƒe akpa geɖe dzi. Mɔ nyuitɔ si dzi nàto aɖe wò afɔkua dzi akpɔtɔe nye be nàƒo asa na kpeɖeŋutɔ siwo me L-tryptophan alo 5-HTP si wowɔ la nono. L-tryptophan, si le dzɔdzɔme nu le nuɖuɖuwo abe koklozi kple tɔmelã si wotsɔ gaze me ene me la ɖuɖu le dedie, gake nusiwo wotsɔ lãgbalẽ wɔe ate ŋu agblẽ nu le wò ŋutilã ŋu.

Togbɔ be atikewɔwɔ koŋ ƒe taɖodzinue nye be woakpɔ wò dzesiwo gbɔ hã la, ahiã hã be nàtsɔ nuwo akpe ɖe wò agbenɔnɔ ŋu, abe gbesiagbe kamedede bɔbɔe ene, be wòakpe ɖe ŋuwò nàse le ɖokuiwò me be yeƒe lãme sẽ. Ðo ŋku edzi ɣesiaɣi be ne èkpɔ dzesi aɖewo siwo mebɔ o, vevietɔ le atike yeye zazã gɔme vɔ megbe la, di atikewɔlawo ƒe aɖaŋuɖoɖo enumake.

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