Ðe wò ʋu ƒe sisi mele ɖiɖim ne èzã atike gɔ̃ hã oa? Mina míasrɔ̃ nu tso hyperaldosteronism ŋu.

Ðe nèbiaa ɖokuiwò ɣeaɖewoɣi be, ‘Nukatae le anyigba dzi la, nye ʋu ƒe sisi maɖiɖi ne mezã atike gɔ̃ hã oa?’? Kuxi sia ke le ame aɖewo hã ŋu. Ɣeaɖewoɣi la, esesẽna be woaɖu woƒe ʋu ƒe sisi dzi, le atike nono vɔ megbe gɔ̃ hã. Le ɣeyiɣi siawo tɔgbe me la, ehiã be míabu eŋu nenye be ate ŋu anye nusi gbɔ wòtso. Egbea, míele nu ƒom tso nɔnɔme aɖe si ƒe dzesiwo kpɔkpɔ sesẽna ɣeaɖewoɣi, gake woate ŋu adae ne wodae nyuie ŋu. Emae nye hyperaldosteronism .

Nukae Nye Hyperaldosteronism ƒe Dɔléle?

Kpuie ko la, hyperaldosteronism nye ne wò adrenal glandwo wɔ lãmetsi aɖe si woyɔna be aldosterone fũ akpa. Bu eŋu ale, aldosterone le abe mɔ̃ɖaŋudɔwɔla sue aɖe si kpɔa míaƒe ʋu ƒe sisi dzi ene. Ekpena ɖe mía ŋu be míaƒe ʋu ƒe sisi nanɔ ɖoɖo nyuitɔ nu to potassium kple sodium ƒe agbɔsɔsɔ si le míaƒe ŋutilã me dzi kpɔkpɔ me.

Fifia ɖewohĩ ànɔ ɖokuiwò biam be, ‘Nukae nye adrenal gland siawo?’ Esiawo nye míaƒe lãmenugbagbeviwo ƒe dɔwɔwɔ ƒe akpa aɖe . Wole abe dɔwɔƒe sue siwo wɔa lãmetsi vovovo siwo míaƒe ŋutilã hiã be wòate ŋu awɔ dɔ gbesiagbe ene. Adrenal gland siawo dometɔ eve le mía si, siwo le míaƒe ayiku tame ŋutɔŋutɔ, abe kposɔ ene.

Nukawoe nye hyperaldosteronism ƒomeviwo?

Aldosteronism ƒomevi vevi eve li.

1. Hyperaldosteronism Gbãtɔ: Woyɔa esia ɣeaɖewoɣi be Conn ƒe dɔléle . Nusi dzɔna le afisia enye be nane gblẽ le wò adrenal glands ŋutɔ ŋu, si wɔnɛ be wowɔa aldosterone fũ akpa. Bu eŋu abe kuxi aɖe le dɔwɔƒe aɖe me eye wole nu geɖe wɔm ene.

2. Secondary Hyperaldosteronism: Esia menye kuxi na adrenal glands o. Enye kuxi aɖe le wò ŋutilã ƒe teƒe bubu si nana be adrenal glands la ʋãna eye wòdzea aldosterone geɖe wɔwɔ gɔme. Esia fia be dɔwɔƒea le dɔ wɔm gaƒoƒo geɖe wu le gotagome ŋusẽkpɔɖeamedzi aɖe ta.

Aleke kee wòɖale o, nusi dona tso eme mlɔebae nye be wò ʋu me aldosterone ƒe agbɔsɔsɔ dzina ɖe edzi, si wɔnɛ be ʋusɔgbɔdɔ (ʋusɔgbɔdɔ) eye wò ʋu me potassium ƒe agbɔsɔsɔ dzi ɖena kpɔtɔna. Woyɔa potassium ƒe ɖiɖi sia be hypokalemia .

Ameka ŋue nɔnɔme sia gblẽa nu le wu? Aleke gbegbe wòbɔe?

Wokpɔa hyperaldosteronism zi geɖe le amesiwo xɔ tso ƒe 30 va ɖo ƒe 50 me.Azɔ hã, nɔnɔme sia bɔ ɖe nyɔnuwo dome vie wu ŋutsuwo.

Esesẽna na numekulawo be woagblɔ alesi tututu esia bɔe, elabena ɣeaɖewoɣi la, wokpɔa dɔlélea le mɔ gbegblẽ nu. Gake numekuku aɖewo ɖee fia be amesiwo ŋu ʋusɔgbɔdɔ le ƒe 5% va ɖo 10% ate ŋu anye hyperaldosteronism gbãtɔ. Eŋutinunyalawo bu akɔnta be amesiwo ƒe ʋusɔgbɔdɔ si atikewo mete ŋu o le la dometɔ siwo ade 25% ate ŋu axɔ dɔléle sia. Eyata, menye nusi mebɔ nenema gbegbe o, alo?

Nukae nye Hyperaldosteronism ƒe dzesiwo?

Hyperaldosteronism ƒe dzesiwo ate ŋu ato vovo tso ame ɖeka gbɔ yi bubu gbɔ, le alesi nɔnɔmea nu sẽe nu. Ðewohĩ dzesi aɖeke madze ame aɖewo ŋu kura o , vevietɔ ne nɔnɔmea mesẽ tututu o.

Gake nɔnɔme sia ƒe dzesi vevitɔ kple esi bɔ wue nye ʋusɔgbɔdɔ (ʋusɔgbɔdɔ) , vevietɔ ʋusɔgbɔdɔ si dzi womate ŋu aɖu bɔbɔe ne wozã atike gɔ̃ hã o.

Tsɔ kpe ɖe eŋu la, ne èkpɔ dzesi bubuwo la, zi geɖe la, ʋusɔgbɔdɔ si sɔ gbɔ va ɖo esi nu sẽ kple/alo potassium ƒe agbɔsɔsɔ si bɔbɔ ɖe ʋua me (hypokalemia) gbɔe wòtsona.

Dzesi siwo ate ŋu ado mo ɖa le ʋusɔgbɔdɔ (ʋusɔgbɔdɔ) ta:

• Taɖuame
• Taɖuame
• Nukpɔkpɔ trɔna
• Yagbɔgbɔ sesẽ

Dzesi siwo ate ŋu ado mo ɖa le potassium ƒe agbɔsɔsɔ si le ʋu me ƒe agbɔsɔsɔ si mede o ta (hypokalemia):

• Lãmetsiwo ƒe gbɔdzɔgbɔdzɔ - Le nɔnɔme sesẽ aɖewo me la, nɔnɔme si sɔ kple lãmetutudɔ hena ɣeyiɣi aɖe ate ŋu ado mo ɖa.
• Lãmetsiwo ƒe ʋuʋu alo ʋuʋu (lãmekawo ƒe ʋuʋu) .
• Ʋuʋudedi kple lãmetutudɔ
• Ɖeɖiteameŋu
• Tsikɔwuame si gbɔ eme (woyɔa esia be polydipsia) .
• Aɖuɖɔɖɔɖɔ enuenu

Fifia èse egɔme, esi dzesi siawo dometɔ aɖewo bɔ ɖe dɔléle bubuwo me ta la, ate ŋu atsi megbe akpa ɣeaɖewoɣi be woade dzesi esia.

Nukae hea esia vɛ?

Nusiwo hea hyperaldosteronism vɛ la toa vovo le alesi wònye gbãtɔ alo evelia nu. Na míalé ŋku ɖe alesi wòwɔe ŋu.

Nusiwo Hea Hyperaldosteronism Gbãtɔ Gbɔna

Abe alesi megblɔe va yi ene la, Primary Hyperaldosteronism nye kuxi le wò adrenal glands ŋutɔ ŋu, si wɔnɛ be wowɔa aldosterone fũ akpa.

Nusi gbɔ esia tsona wue nye dɔdzẽ siwo menye kansa o siwo woyɔna be adrenal adenomas siwo dzɔna le adrenal glands me . Esiawo nye dɔdzẽ suesuesue siwo megblẽa nu le ame ŋu o, gake woate ŋu ana lãmetsi si nye aldosterone nado fũu akpa.

Tsɔ kpe ɖe eŋu la, nu bubu geɖewo hã li siwo mebɔ o siwo gbɔ wòtsona :

• Unilateral adrenal hyperplasia - Esia fia be adrenal gland ɖeka si le akpa ɖeka koe vuvu, lolona, ​​eye wòwɔa lãmetsi geɖe.
• Aldosterone-producing adrenocortical carcinomas - Esiawo nye kansa ƒe dɔdzẽwo. Ke hã, womebɔ kura o.
• Ƒome ƒe hyperaldosteronism type 1 - Esia nye nɔnɔme si ƒe domenyinyi tso dzilawo gbɔ na ɖeviwo.

Nusiwo hea Hyperaldosteronism Evelia vɛ

Nu vevitɔ si gbɔ aldosteronism evelia tsonae nye ʋu si ɖoa wò ayiku me ƒe agbɔsɔsɔ si dzi ɖena kpɔtɔna .

Be nàse alesi esia dzɔnae gɔme la, ele be nànya be lãmetsi si nye aldosterone nye lãmetsiŋusẽ ƒe kɔsɔkɔsɔ sesẽ aɖe si kpɔa míaƒe ʋu ƒe sisi dzi la ƒe akpa aɖe. Bu eŋu abe kɔsɔkɔsɔ ƒe nuwɔna ene.

Woyɔa ɖoɖo sia be renin-angiotensin-aldosterone ɖoɖo . Ewɔa dɔ ale:

1. Ne wò ŋutilã se ʋu ƒe sisi alo sodium ƒe agbɔsɔsɔ si ɖiɖi le wò ʋu me la, wò ayikuwo ɖea enzyme aɖe si woyɔna be renin .

2. Renin sia yia edzi trɔa nusi woyɔna be angiotensin (si nye angiotensin ƒe ŋgɔdonya) si wò aklã wɔna wòzua angiotensin I. (Angiotensin nye lãmetsi aɖe si xea mɔ na míaƒe ʋukawo.)

3. Eyome, angiotensin I sia va zua angiotensin II .

4. Mlɔeba la, angiotensin II siae xea ʋukawo ɖe edzi eye wòʋãa adrenal glands be woaɖe lãmetsi si nye aldosterone .

Azɔ bu eŋu kpɔ, ne le susu aɖe ta ʋu si yia ayikuwo me dzi ɖe kpɔtɔ la, ayikuawo asusu be, ‘Oo, nye ʋu ƒe sisi ɖiɖi.’ Emegbe wowɔa renin-angiotensin-aldosterone ƒe ɖoɖo sia ŋudɔ vodadatɔe. Nusi dona tso emee nye be aldosterone ƒe agbɔsɔsɔ le ŋutilãa me dzina ɖe edzi, togbɔ be mehiã ŋutɔŋutɔ o hã.

Nusiwo ate ŋu aɖe ʋu ƒe sisi yi ayikuwo me dzi akpɔtɔ eye wòahe hyperaldosteronism evelia vɛWo dometɔ ʋɛ aɖewoe nye esi:

• Abstructive renal artery disease - abe tsi ƒe pɔmpi si xe ene.
• Ayiku me ʋusɔgbɔdɔ
• Nɔnɔme siwo me tsi ƒoa ƒu ɖe ŋutilã me (edema) , le kpɔɖeŋu me:
• Dzi ƒe dɔmawɔmawɔ nyuie
• Aklã ƒe ʋuka me dɔléle
• Nephrotic syndrome nye ayikudɔléle.

Aleke nèwɔna dea dzesi esia?

Zi geɖe la ɖɔkta toa ʋudodokpɔ me dea dzesi hyperaldosteronism . Gake womekpɔa dɔlélea le ame geɖe ŋu gbeɖe o elabena nu bubu geɖewo hã li siwo gbɔ ʋusɔgbɔdɔ tsona kple afɔku siwo ate ŋu ahe ʋusɔgbɔdɔ vɛ.

Dzesi siwo bɔ siwo ɖee fia be ɖewohĩ hyperaldosteronism le ŋuwò dometɔ aɖewoe nye:

• Ʋusɔgbɔdɔ si te ŋu nɔa te ɖe atikewo nu.
• Nusiwo do tso wò ʋudodokpɔ ƒe nyatakaka si me elektrikŋusẽ le mee nye esi:
• Sodium ƒe agbɔsɔsɔ si sɔ gbɔ vie (hypernatremia) .
• Magnesium ƒe agbɔsɔsɔ si bɔbɔ vie (hypomagnesemia) .
• Azɔ hã, potassium ƒe agbɔsɔsɔ si bɔbɔ (hypokalemia) .

Ne wò ɖɔkta susui be ate ŋu anye be hyperaldosteronism le ŋuwò le dzesi kple dzesi siawo ta la, anɔ eme be abia be woawɔ ʋudodokpɔ tɔxɛ eve: Plasma Renin Concentration (PRC) alo Plasma Renin Activity (PRA) .

• Ne Primary Hyperaldosteronism , le ŋuwò la, wò PRC kple PRA ƒe agbɔsɔsɔ aɖiɖi wu alesi wòle dzɔdzɔmee.
• Ne secondary hyperaldosteronism , le ŋuwò la, agbɔsɔsɔ siawo asɔ gbɔ wu alesi wòle dzɔdzɔmee.

Tsɔ kpe ɖe eŋu la, ate ŋu ahiã hã be woawɔ aldosterone ƒe dɔlékuiwutike ƒe dodokpɔ . Dodokpɔ sia bia be woana sodium (dze) agbɔsɔsɔme aɖe wò to nu me alo to dze (IV) dodo me le ɣeyiɣi aɖe me. Emegbe, woxɔa wò aɖuɖɔtoewo le gaƒoƒo 24 me eye wodzidzea aldosterone agbɔsɔsɔme si le aɖuɖɔ ma me le nudokpɔƒe.

Ne dodokpɔ siawo ɖo kpe edzi be hyperaldosteronism le ŋuwò la, wò ɖɔkta ate ŋu aɖe gbe be woawɔ dodokpɔ bubuwo atsɔ anya nusi gbɔ wòtso. Le kpɔɖeŋu me, CT scan (computed tomography scan) be woakpɔe ɖa be dɔdzẽ si menye kansa o ye le hyperaldosteronism la hem vɛ hã.Woate ŋu abia tso asiwò be nàwɔ nɔnɔmetatawo dodokpɔ .

Nukawoe nye atike siwo wozãna na esia?

Atikewɔwɔ na hyperaldosteronism nɔ te ɖe nusi gbɔ wòtso dzi, gake taɖodzinu vevitɔe nye be nàɖu wò ʋu ƒe sisi dzi .

• Le hyperaldosteronism gbãtɔ, si nye nɔnɔme si adrenal gland ƒe dɔdzẽ hena vɛ gome la, zi geɖe la, ɖɔktawo kafua amekoko be woaɖe dɔdzẽa ɖa . Gake le go aɖewo me la, woate ŋu atsɔ atike ɖeɖeko ada dɔdzẽ siawo. Le amekoko vɔ megbe gɔ̃ hã la, ʋusɔgbɔdɔ anɔ ŋuwò kokoko, eya ta ahiã be nàno atike hafi aɖu edzi.

• Wodaa aldosteronism evelia to wò ʋu ƒe sisi dzi ɖuɖu kple atikewo me, eye wodaa nusi gbɔ wòtso hã (e.g., dzidɔ) .

Atike ƒomevi vovovowo li siwo ate ŋu akpe ɖe ame ŋu le hyperaldosteronism me:

• Spironolactone (Spironolactone - Aldactone®) ƒe ʋuʋudedi.
• Eplerenone (Eplerenone - Inspra®) ƒe ʋuƒoƒo.
• Amiloride (Amiloride - Midamor®) ƒe ʋuƒoƒo.

Nu ɖeka si wòle be wòanɔ susu me na mí enye be atike siwo xea mɔ na aldosterone, abe Spironolactone , ene zazã ɣeyiɣi didi ate ŋu ahe nugbegblẽ aɖewo vɛ na ŋutsuwo. Le kpɔɖeŋu me, tsitretsitsi ƒe dɔmawɔmawɔ nyuie kple nyɔnuwo ƒe dɔmawɔmawɔ nyuie ate ŋu adzɔ. Eyata ele vevie be nàƒo nu kple wò ɖɔkta tso atike si nyo na wò, ɣeyiɣi didi si wòle be nànoe, kple nusiwo wògblẽna le ame ŋu ŋu.

Ðe woate ŋu axe mɔ ɖe esia nua?

Le nyateƒe me la, zi geɖe la, naneke meli nàte ŋu awɔ atsɔ axe mɔ ɖe dɔléle sia si nye hyperaldosteronism nu o. Elabena tɔtrɔ siwo vaa míaƒe ŋutilã ƒe dɔwɔwɔ le ememe gbɔe wòtsona. Gake àte ŋu alé wò lãmesẽ bliboa me ɖe asi to agbenɔnɔ si me lãmesẽ le dzi, nuɖuɖu si da sɔ ɖuɖu, kple kamedede me.

Nukae nye nɔnɔme sia ƒe ŋgɔdonya?

Alesi woagblɔe ɖi be hyperaldosteronism anɔ te ɖe nusi gbɔ wòtso dzi.

• Zi geɖe la, ne wokpɔ dɔléle si nye primary hyperaldosteronism , ne wokpɔe kaba eye wodae nyuie la, dona tso eme nyuie . Ne woɖe dɔdzẽ aɖe ɖa la, zi geɖe la, wokpɔa nɔnɔmea dzi.
• Evelia ƒe HyperaldosteronismDɔlélea ƒe etsɔme nɔ te ɖe alesi woate ŋu aɖu atikewɔwɔ ƒe nɔnɔme si le ete (e.g., dzidɔ, aklãdɔ) dzi nyuie dzi.

Kuxi vevi siwo ate ŋu ado mo ɖa le hyperaldosteronism tae nye dzitodzito me nya siwo ʋusɔgbɔdɔ hena vɛ. Esiawo dometɔ aɖewoe nye:

• Atrial fibrillation - dzi ƒe tsotso si mesɔ o.
• Left ventricular hypertrophy - dzia ƒe miamexɔ ƒe gliwo ƒe ƒoƒo.
• Dzidɔ
• Gbagbãdᴐ

Esia tae wòle vevie ŋutɔ be woanya dɔléle sia kaba eye woakpɔ atike nyuitɔ.

Ɣekaɣie wòle be makpɔ ɖɔkta?

Ne wokpɔe be hyperaldosteronism le ŋuwò la, ele be nàyi ɖɔkta gbɔ edziedzi be nàkpɔ egbɔ be atike si woŋlɔ na wò la le dɔ wɔm nyuie . Ele vevie ŋutɔ hã be nàwɔ ɖe wò ɖɔkta ƒe mɔfiamewo dzi.

Ne dzesi yeye aɖewo dze le ŋuwò, alo nède dzesii be tɔtrɔ aɖe va le dzesi siwo li xoxo ŋu la , na wò ɖɔkta nanya enumake.

Nu vevitɔe nye be, ne ʋusɔgbɔdɔ si me atikewo mete ŋu ɖuna o le ŋuwò la, ƒo nu kple wò ɖɔkta tso nusiwo ŋu nètsi dzi ɖo ŋu, abe, "Ðe mate ŋu anye be hyperaldosteronism le ŋunyea?" Ate ŋu ada wò nɔnɔmea kpɔ eye wòakafu dodokpɔ ɖesiaɖe si hiã.

Ðo ŋku edzi be nu geɖe li siwo gbɔ ʋusɔgbɔdɔ tsona. Wo dometɔ ɖeka koe nye hyperaldosteronism. Nya nyuiae nye be esia nye dɔléle si woate ŋu ada.

Gbedasi si Wotsɔ Yi Aƒeme

Enyo, eyata mele mɔ kpɔm be fifia miese nusi ŋu míeƒo nu tsoe, Hyperaldosteronism, gɔme nyuie wu. Nu aɖewo siwo wòle be wòanɔ susu me na wòe nye esi:

• Hyperaldosteronism nye lãmetsi si nye aldosterone si adrenal glandwo wɔ fũ akpa .
• Esia ate ŋu ana ʋusɔgbɔdɔ (ʋusɔgbɔdɔ) kple potassium ƒe agbɔsɔsɔ si le ʋu me naɖiɖi (hypokalemia) .
• Wole ƒomevi vevi eve: Gbãtɔ ( kuxi si le adrenal glands ŋutɔ ŋu) kple Secondary (adrenal gland ƒe ʋuʋu le kuxi aɖe si le teƒe bubu ta).
• Ne ʋusɔgbɔdɔ si dzi atikewo mete ŋu ɖuna o le ŋuwò la, ele be nàke ɖi le esia ŋu.
• Wotoa ʋudodokpɔwo dzi dea dzesi esia .
• Atikewɔwɔ bia be woaɖu ʋu ƒe sisi dzi ahada nusi gbɔ wòtsona .
• Ne wokpɔe hedae kaba la, woate ŋu akpɔ nu nyuiwo .

Ne nya bubu aɖewo gale asiwò ku ɖe esia ŋu la, bia wò ɖɔkta faa. Nɔ lãmesẽ me!

` Hyperaldosteronism, Hyperaldosteronism, Aldosterone, Ʋusɔgbɔdɔ, ʋusɔgbɔdɔ, Potassium, Adrenal glands, Conn ƒe dɔléle