Ðe dzesi wɔnukuwo le fu ɖem na wò le calcium ƒe agbɔsɔsɔ si mede wò ŋutilã me o ta? Ate ŋu anye hypoparathyroidism!

Ðe nèsena le ɖokuiwò me ɣeaɖewoɣi be yeƒe ŋutilã le vevem si womate ŋu aɖe oa? Ðe wò abɔwo kple afɔwo tsia dzodzodzoea? Alo ɖeko nèsena le ɖokuiwò me be yeƒe ŋutigbalẽ le tsatsam ko? Nusiwo gbɔ nusiawo tso dometɔ ɖeka ate ŋu anye nɔnɔme aɖe si woyɔna be hypoparathyroidism, si ŋu míele nu ƒom tsoe egbea. Mègatsi dzi o, togbɔ be esia nye dɔléle si mebɔ o hã la, woate ŋu aɖu edzi ne wokpɔe dze sii eye wodae nyuie. Mina míaƒo nu tso esia ŋu tsitotsito.

Nukae nye Hypoparathyroidism?

Kpuie ko la, hypoparathyroidism nye ne wò ʋu mewɔ Parathyroid Hormone (PTH) ʋɛ akpa alo mewɔa naneke kura o. Lãmetsi sia le vevie na calcium kple phosphorus ƒe agbɔsɔsɔ si le wò ŋutilã me dzi kpɔkpɔ. Eyata, ne wò PTH ƒe agbɔsɔsɔ le sue la, wò ʋu me calcium ƒe agbɔsɔsɔ dzi ɖena kpɔtɔna – míeyɔna esia be hypocalcemia – eye wò ʋu me phosphorus ƒe agbɔsɔsɔ dzina ɖe edzi.

Zi geɖe la, nɔnɔme sia nɔa anyi didi , si fia be ate ŋu anɔ anyi le eƒe agbemeŋkekewo katã me. Gake le go aɖewo me la, ate ŋu anyo ɖe edzi hena ɣeyiɣi aɖe hã.

Eyata nukawoe nye parathyroid gland siawo?

Bu eŋu kpɔ, le míaƒe kɔ ƒe ŋgɔgbe, le kpakpaluʋui ƒe nɔnɔme me la, Thyroid Gland le afima. Le Thyroid Gland ma megbe la, lãkusi ene li, eye zi geɖe la, woƒe lolome anɔ abe pea sue aɖe ene. Woyɔa esiawo be Parathyroid Glands . Esiawo nye Endocrine System, si wɔa lãmetsiŋusẽwo le míaƒe ŋutilã me la ƒe akpa aɖe.

Ɣeaɖewoɣi la, lãkusi ene siawo ate ŋu anɔ teƒe bubu le kɔ, akɔta, alo nuɖuɖutome gɔ̃ hã. Woyɔa esiawo be ectopic parathyroid glands .

Dɔ vevitɔ si parathyroid gland siawo wɔnae nye be woawɔ parathyroid hormone (PTH). PTH siae nana calcium ƒe agbɔsɔsɔ si le míaƒe ʋu me nɔa agbɔsɔsɔ nyuitɔ me.

• Ne PTH dzi ɖe kpɔtɔ: Calcium si le ʋu me dzi ɖena kpɔtɔna (Hypocalcemia).
• Ne PTH dzi ɖe edzi: Calcium si le ʋu me dzina ɖe edzi (Hypercalcemia).

Menye ema ɖeɖeko o, ke PTH lãmetsi sia kpena ɖe ame ŋu hã be wòaɖu phosphorus kple vitamin D ƒe agbɔsɔsɔ si le ʋu kple ƒuwo me dzi.

Nukae nye calcium? Nukae wòwɔna na míaƒe ŋutilã?

Calcium nye mineral vevi aɖe na míaƒe ŋutilã. Ènya be calcium si le míaƒe ŋutilã me ƒe akpa gãtɔ nɔa míaƒe ƒuwo mea? Gake ele be calcium agbɔsɔsɔme aɖe hã nanɔ ʋua me.

Mina míalé ŋku ɖe nu vevi aɖewo siwo menye calcium le ʋua me o ŋu:

• Ekpena ɖe míaƒe lãmekawo ŋu wòwɔa dɔ .
• Ekpena ɖe lãmekawo ŋu be woatsi eye woaɖe dzi ɖi . Esiae na míete ŋu ʋãa míaƒe abɔwo hezɔna.
• Ne míexɔ abi eye ʋu le dodom le mía ŋu la, ekpena ɖe mía ŋu be ʋua natsi .
• Ele vevie be míaƒe dzi nawɔ dɔ nyuie .

Fifia èse alesi hypocalcemia (ʋu me calcium si bɔbɔ) si tsoa hypoparathyroidism gbɔ ate ŋu akpɔ ŋusẽ ɖe nu geɖe dzii gɔme. Calcium hã hiã be ƒuwo nasẽ. Gake hypocalcemia nye calcium ƒe ɖiɖi le ʋu me, ke menye calcium ƒe ɖiɖi le ƒuwo me o.

Ðe hypoparathyroidism ate ŋu ana elektrikŋusẽ ƒe dadasɔ masɔmasɔa?

Ẽ, keŋkeŋ. Calcium kple Phosphorus nye elektrikŋusẽ ƒomevi eve . Elektrikŋusẽwo nye tomenu siwo me elektrikŋusẽ le le míaƒe ŋutilã me eye wowɔa dɔ vevi geɖe. Le hypoparathyroidism me la, calcium si le ʋua me dzi ɖena kpɔtɔna eye phosphorus dzina ɖe edzi, si wɔnɛ be elektrikŋusẽ ƒe dadasɔ masɔmasɔ. Ele vevie ŋutɔ be woaɖɔ esia ɖo.

Nu ɖeka gali hã. Magnesium nye elektrikŋusẽnamɔ̃ vevi bubu. Ne magnesium ƒe agbɔsɔsɔ le ʋu me dzi ɖe kpɔtɔ (Hypomagnesemia) , ate ŋu anye nusi gbɔ hypoparathyroidism hã tso. Elabena magnesium hiã vevie hafi parathyroid lãkusiwo nate ŋu awɔ dɔ nyuie.

Vovototo kae le Hypoparathyroidism kple Hyperparathyroidism dome?

Ŋkɔ eve siawo ɖi wo nɔewo vie, eyata woate ŋu atɔtɔ ame. Le atikewɔwɔ me la, ŋgɔdonya "Hypo" gɔmee nye "nu sue" alo "mesɔ gbɔ o." Gbãtɔ si nye "Hyper" gɔmee nye "geɖe wu" alo "kɔkɔ wu."

• Hypoparathyroidism: Parathyroid glands mewɔa parathyroid hormone (PTH) si sɔ gbɔ o, si wɔnɛ be calcium ƒe agbɔsɔsɔ si le ʋua me dzi ɖena kpɔtɔna.
• Hyperparathyroidism: Parathyroid glands wɔa PTH fũ akpa, si wɔnɛ be calcium dzina ɖe edzi le ʋua me.

Ele bɔbɔe, alo?

Amekae xɔa nɔnɔme sia si woyɔna be hypoparathyroidism?

Esia ate ŋu adzɔ ɖe ame tsitsiwo kpakple ɖevi suewo hã dzi. Gake abe alesi míegblɔe va yi ene la, esia nye nɔnɔme si mebɔ kura o .

• Le ame tsitsiwo me: Zi geɖe la, esia tsoa nusiwo gblẽ le parathyroid glands ŋu le vo me le kɔ ƒe dɔwɔwɔ me – le kpɔɖeŋu me, thyroid dɔwɔwɔ.
• Le ɖeviwo gome: Zi geɖe la, domenyiŋusẽfianu ƒe nɔnɔme aɖe si woyɔna be DiGeorge Syndrome si le ɖeviwo ŋu gbɔe esia tsona.

Le dukɔ abe Amerika ene gɔ̃ hã me la, wogblɔ be nɔnɔme sia gblẽa nu le ame siwo mede akpe alafa eve o ŋu. Eyata le míaƒe dukɔa me la, ate ŋu anɔ sue wu gɔ̃ hã.

Nukawo koŋue hea hypoparathyroidism vɛ?

Susu geɖewo tae wòle alea ɖo.

• Nusiwo gblẽna le parathyroid glands ŋu: Esiae nye nusi gbɔ wòtsona wu. Anɔ abe 75 le alafa me (75%) leDɔnɔwo va xɔa nɔnɔme sia ne lãkusiawo gblẽ le vo me le kɔ alo lãkusi ƒe dɔwɔwɔ na wo me. Ɣeaɖewoɣi la, nɔnɔme sia ate ŋu adzɔ le amekokoa megbe ƒe geɖe. Gake zi geɖe la, edzea egɔme le amekokoa megbe kpuie. Zi geɖe la, ʋumenugbagbeviɣidɔ si dzɔna le mɔ sia nu la nɔa anyi ɣeyiɣi kpui aɖe, gake le ame aɖewo gome la, ate ŋu anɔ anyi ɖaa. Anɔ eme kura be keklẽŋusẽdɔdamɔnu magblẽ nu le lãkusi siawo ŋu o.

• Domenyiŋusẽfianu ƒe nɔnɔmewo: Dɔlékui siwo mede ewo le alafa me o (10%) tso domenyiŋusẽfianu ƒe nɔnɔmewo gbɔ. Esiawo dometɔ si bɔ wue nye DiGeorge Syndrome . Esia nye domenyiŋusẽfianu ƒe domenyiŋusẽfianu ƒe nɔnɔme. Vidzĩ siwo wodzi kple dɔléle sia mekpɔa parathyroid glands o. Eyata esi womewɔa PTH o ta la, hypoparathyroidism si nɔa anyi didi le wo ŋu. Wogblɔ be ɖevi siwo ŋu hypoparathyroidism le dometɔ siwo ade 60% xɔ DiGeorge Syndrome. Ate ŋu atso domenyiŋusẽfianu ƒe dɔléle bubu siwo do ƒome kple tokunɔnyenye kple ayikudɔ hã gbɔ.

• Dɔlélenutsiŋutete ƒe Dɔlélewo: Ɣeaɖewoɣi la, mía ŋutɔwo ƒe dɔlélenutsiŋutete dzea parathyroid lãkusiwo dzi vodadatɔe. Dɔléle mawo dometɔ ɖeka si nye autoimmune polyglandular syndrome ƒomevi 1 . Esia hea hypoparathyroidism si nɔa anyi ɖaa vɛ. Ate ŋu atso nɔnɔme siwo woyɔna be Addison ƒe dɔléle kple ʋusɔgbɔdɔ si gblẽa nu le ame ŋu hã gbɔ .

• Dɔléle siwo gena ɖe lãme na ame: Le dɔléle ƒe nɔnɔme aɖewo me la, nusiwo le abe iron (abe alesi wòle le ʋumenugbagbeviɣidɔ me ene) kple akɔbli (abe alesi wòle le Wilson ƒe dɔlélea me ene) ate ŋu aƒo ƒu ɖe parathyroid lãkusiwo me. Azɔ hã, kansa ƒe dɔlékui aɖewo siwo kaka ɖe teƒe bubuwo ate ŋu agblẽ nu le lãkusi siawo ƒe dɔwɔwɔ ŋu, si ana ʋumenugbagbeviɣidɔ natsi.

• Magnesium ƒe Agbɔsɔsɔme Si Mebɔ O: Abe alesi míegblɔe va yi ene la, magnesium hiã vevie hafi parathyroid glands nate ŋu awɔ dɔ nyuie. Magnesium ƒe agbɔsɔsɔ si mede ʋua me o (hypomagnesemia) ate ŋu ana ame nazu hypoparathyroidism. Woyɔa esia be functional hypoparathyroidism . Zi geɖe la, nɔnɔme sia nu tsona ne magnesium ƒe agbɔsɔsɔ gaɖo eŋu.

Nukae nye hypoparathyroidism ƒe dzesiwo?

Zi geɖe la, nɔnɔme sia doa mo ɖa vivivi ŋutɔ. Eyata dzesiawo ate ŋu anye esiwo menya kpɔna dzea sii bɔbɔe o. Ame aɖewo menya gɔ̃ hã be dɔlélea le yewo ŋu o ƒe geɖe.

Esiawoe nye dzesi siwo woate ŋu akpɔ le goawo katã me:

• Nuyiwo, asibidɛwo, kple afɔbidɛwo ƒe ʋuʋu.
• Lãmetsiwo ƒe ʋuʋu.Èɖo ŋku edzi be fu nɔa wò afɔwo ŋu ɣeaɖewoɣi le zã mea? Nu mawo tɔgbe, gake ne edzɔna enuenu la, ate ŋu anye calcium ƒe anyimanɔmanɔ sia ƒe dzesi.
• Lãmetsiwo ƒe ʋuʋu (Tetany).
• Ƒodo ƒe vevesese.
• "Ahɔhɔ̃ ƒe afu" nye nɔnɔme si me wòsesẽna na wò be wò susu nanɔ nu ŋu eye nèsena le ɖokuiwò me be yeƒe susu tɔtɔ vie.
• Dzi ƒe tsotso ƒe masɔmasɔ (Arrhythmia).
• Aɖabɛ siwo le gbagbãm.
• Taɖa ƒuƒu kple ŋutigbalẽ ƒuƒu si me ʋuʋudedi le.
• Ŋkudɔ ƒe dzedzeme.
• Aɖu ƒe ʋuʋudedi ƒe gbɔdzɔgbɔdzɔ le ɖeviwo me.

Aleke ɖɔktawo wɔna dea dzesi nɔnɔme sia?

Zi geɖe la, wosusuna be ʋumenugbagbeviɣidɔ le ame ŋu eye woɖoa kpe edzi ne dodokpɔwo ɖee fia be calcium kple parathyroid hormone (PTH) ƒe agbɔsɔsɔ le ame ƒe ʋu me le sue.

Esi wònye be dzesiawo menya kpɔna dzea sii bɔbɔe o ta la, ɖɔktawo va kea ɖe nɔnɔme sia ŋu ɣeaɖewoɣi "le vo me." Eyae nye be ne wokpɔ calcium si mebɔ o le ʋua me le ʋudodokpɔ edziedzi me be dɔléle bubu aɖe le wo ŋu ko hafi wodzea edidi gɔme.

Ne woɖo kpe edzi be PTH lãmetsi kple calcium mesɔ gbɔ ɖe ame aɖe ƒe ʋu me zi eve le ɣleti ade me o la, wobua esia be enye hypoparathyroidism si nɔa anyi didi .

Dodokpɔ ka ƒomevie wowɔna na esia?

Ne dzesi siawo le ŋuwò la, wò ɖɔkta awɔ wò ŋutilã dodokpɔ ahabia wò dzesiwo, ƒomea ƒe atikewɔwɔ ŋutinya, kple atike siwo nènona.

Tsɔ kpe ɖe eŋu la, woate ŋu awɔ dodokpɔ siwo gbɔna la dometɔ ɖeka alo esi wu nenema:

• Parathyroid hormone (PTH) ƒe ʋudodokpɔ.
• Calcium ƒe ʋudodokpɔ.
• Phosphorus ƒe ʋudodokpɔ.
• Magnesium ƒe ʋudodokpɔ.
• Gaƒoƒo 24 ƒe aɖuɖɔ dodokpɔ: Esia dzidzea calcium agbɔsɔsɔme si dona le aɖuɖɔ me.

Ɣeaɖewoɣi la, wò ɖɔkta ate ŋu aɖe gbe be woawɔ dodokpɔ bubuwo atsɔ akpɔe ɖa be dɔléle sia ƒe nugbegblẽ le ame ŋu vevie wu hã. Le kpɔɖeŋu me:

• Electrocardiogram (ECG alo EKG): Eléa ŋku ɖe dzi ƒe tsotso ƒe masɔmasɔwo ŋu hã.
• Computed tomography (CT) scan: Woléa ŋku ɖe calcium si le ahɔhɔ̃a me ŋu (Brain Calcifications).

Aleke wowɔa nu ɖe ​​esia ŋui?

Taɖodzinu vevitɔ si le hypoparathyroidism dada ŋue nye be wòaɖe dzesiawo dzi akpɔtɔ eye wòana calcium kple mineral bubuwo ƒe agbɔsɔsɔ si le wò ŋutilã me naɖo afisi sɔ.

Woate ŋu awɔ nusiwo gbɔna abe atikewɔwɔ ene:

• Calcium Carbonate kple Vitamin D ƒe kpeɖeŋutɔ nana:Ahiã be ame geɖe siwo ŋu hypoparathyroidism le nano calcium kple vitamin D ƒe atikekuiwo alo tsiwo le woƒe agbemeŋkekewo katã me. Esiae nye dɔléle sia dada vevitɔ kple gbãtɔ. Vitamin D hiã vevie be míaƒe ŋutilã nate ŋu axɔ calcium nyuie. Eyata ne hypoparathyroidism le ŋuwò la, ahiã be nàno atike siawo evea siaa.
• Nuɖuɖu si me calcium sɔ gbɔ ɖo eye phosphorus mesɔ gbɔ ɖe eme o: Wò ɖɔkta ate ŋu aɖo aɖaŋu na wò be nàɖu nuɖuɖu siwo me calcium sɔ gbɔ ɖo wu (notsi, cheese, yogurt, amagbe damawo) eye nàɖe nuɖuɖu siwo me phosphorus sɔ gbɔ ɖo (lã siwo ŋu wotrɔ asi le, ahanono abe cola ene) dzi akpɔtɔ. Gake esi wònye be esesẽna be woakpɔ calcium si sɔ tso nuɖuɖu ɖeɖeko me ta la, ate ŋu ahiã be woano kpeɖeŋutɔtikewo.
• Parathyroid hormone (PTH) dodo: Ne calcium kple vitamin D kpeɖeŋutɔ ɖeɖe mekpɔ ŋusẽ ɖe wò nɔnɔmea dzi o la, wò ɖɔkta ate ŋu atso nya me be yeado parathyroid hormone (PTH) na wò.

Ðe atikewɔwɔa ƒe nugbegblẽ aɖewo lia?

Ẽ, ɣeaɖewoɣi ne vitamin D kple calcium agbɔsɔsɔme si wonana abe atikewɔwɔ ene sɔ gbɔ akpa la, calcium ƒe agbɔsɔsɔ si le ʋua me ate ŋu asɔ gbɔ akpa. Woyɔa esia be hypercalcemia . Esia gblẽa nu le ŋutilã hã ŋu. Eyata ele be nàdo ʋu kpɔ edziedzi akpɔe ɖa be wò atikewɔwɔa le dɔ wɔm nyuie eye wò calcium ƒe agbɔsɔsɔ sɔ hã.

Afɔku sue aɖe ŋutɔ li be woaxɔ ƒumekansa ƒomevi aɖe si woyɔna be osteosarcoma ne wozã parathyroid hormone (PTH) ɣeyiɣi didi. Eyata ɖɔktawo kafu atike sia dodo ɖe lãme na ame le nɔnɔme sesẽ ŋutɔwo me ko, evɔ atikewɔwɔ bubuwo medze edzi o.

Nukawoe nye nusiwo ate ŋu ahe nɔnɔme sia vɛ?

Nu geɖe li siwo nana afɔku si le hypoparathyroidism xɔxɔ me dzina ɖe edzi:

• Esi wowɔ dɔ nɛ nyitsɔ laa le kɔ alo lãkusi me ta.
• Ƒome ŋutinya si ku ɖe parathyroid gland dɔlélewo ŋu.
• Dɔléle aɖewo siwo dɔlélenutsiŋutete wɔna siwo gblẽa nu le lãmenugbagbeviwo ƒe dɔwɔwɔ ŋu, abe Addison ƒe dɔléle ene, ƒe amesinɔnɔ.

Nukae nye nɔnɔme sia ƒe ŋgɔdonya?

Zi geɖe la, mɔkpɔkpɔ na hypoparathyroidism nyo, vevietɔ ne wokpɔ dɔlélea dze sii kaba eye wodze atikewɔwɔ nyuitɔ gɔme.

Gake ne nɔnɔme sia na nuwo abe ŋkudɔ, ahɔhɔ̃ me kpewo, kple aɖu ƒe tɔtrɔ ene la, esesẽna be woatrɔ wo. Esia tae dɔlélea didi kaba le vevie ɖo.

Ɣeyiɣi didi kae nɔnɔme sia anɔ anyi?

Zi geɖe la, hypoparathyroidism nye dɔléle si nɔa anyi didi, si fia be enɔa anyi le eƒe agbemeŋkekewo katã me. Ke hã, hypoparathyroidism hã ate ŋu anɔ anyi ɣeyiɣi kpui aɖe le nu aɖewo ta (e.g., magnesium ƒe anyimanɔmanɔ, ɣeyiɣi kpui aɖe ƒe dɔwɔwɔ le amekoko megbe).

Nukawoe nye kuxi siwo ate ŋu ado tso esia me?

Ne womeda hypoparathyroidism nyuie o la, kuxi vovovo siwo nɔa anyi didi ate ŋu ado mo ɖa:

• Ayikuwo ƒe dɔwɔwɔ ŋuti nyawo.
• Ayiku me kpewo.
• Ŋku ƒe ʋuʋu.
• Calcium ƒe ƒuƒoƒo ɖe ahɔhɔ̃a ƒe akpa vovovowo.

Nɔnɔme sia, vevietɔ le ɖeviwo gome, ate ŋu ahe kuxiwo abe:

• Tsitsi nyuie o.
• Aɖudɔdada ƒe nyawo.
• Susu ƒe tsitsi blewu.

Ele vevie ŋutɔ be míade dzesii be ne calcium ƒe agbɔsɔsɔ si le ʋua me dzi ɖe kpɔtɔ kpata eye wòɖiɖi vevie (Acute Hypocalcemia), ne womedae kaba o la, ate ŋu ahe nɔnɔme siwo ate ŋu ade ame ƒe agbe afɔku me abe alɔ̃madɔmadɔ kple gbɔgbɔ sesẽ le lãkusi ƒe ʋuʋu ta ene vɛ . Ne èkpɔ dzesi siawo (e.g. lãmekawo ƒe ʋuʋu vevie, ʋuʋu) la, ele be nàyi kɔdzi si te ɖe ŋuwò enumake.

Ɣekaɣie wòle be nàkpɔ ɖɔkta?

• Ne dzesi aɖewo le ŋuwò siwo nèsusu be ate ŋu anye hypoparathyroidism la, kpɔ egbɔ be yeyi ɖɔkta gbɔ.
• Ne wokpɔ dɔléle si nye hypoparathyroidism le ŋuwò xoxo la, ele be nàna woalé ŋku ɖe wò ʋu me calcium ƒe agbɔsɔsɔ ŋu edziedzi abe alesi wò ɖɔkta gblɔe ene be nàkpɔ egbɔ be èle atike nyuitɔ xɔm hã.
• Abe alesi míegblɔe va yi ene la, ne èkpɔ dzesi siwo nye hypocalcemia sesẽ, abe lãmekawo ƒe ʋuʋu sesẽ kpata alo alɔ̃madɔmadɔ ene la , yi kɔdzi si te ɖe ŋuwò enumake.

Nu vevitɔ kekeake siwo dzi wòle be nàɖo ŋkui (Take-Home Message) .

Hypoparathyroidism nye dɔléle si mebɔ o, gake woate ŋu adae eye woate ŋu akpɔ egbɔ . Dzesiawo ate ŋu anye esiwo menya kpɔna dzea sii bɔbɔe o ɣeaɖewoɣi, si wɔnɛ be esesẽna be woade dzesii. Eyata ele vevie be nàgblɔe na wò ɖɔkta ne afɔku aɖewo le ŋuwò na nɔnɔme sia (le kpɔɖeŋu me, ne wowɔ dɔ na wò le kɔ nyitsɔ laa alo ne parathyroid dɔléle le wò ƒomea me).

Ʋudodokpɔ bɔbɔe ʋɛ aɖewo ate ŋu akpɔ wò parathyroid hormone (PTH) kple calcium ƒe agbɔsɔsɔ. Ne ède dzesi nɔnɔme sia kaba la, àte ŋu adze atikewɔwɔ nyuitɔ gɔme, axe mɔ ɖe kuxiwo nu, eye nànɔ agbe le lãmesẽ me. Eyata, mègatsi dzodzodzoe o, ke boŋ nya esia. Ne nane si ŋu nètsi dzi ɖo la, mègahe ɖe megbe le nuƒoƒo kple wò ɖɔkta me o.

` Hypoparathyroidism, Hypoparathyroidism, Parathyroid glands, Parathyroid lãmetsi, PTH, Calcium, Hypocalcemia, Phosphorus, Vitamin D, Elektrolytes, Dzesiwo, Atikewɔwɔ