Ðe phosphate mesɔ gbɔ ɖe wò ʋu me oa? Mina míaƒo nu tso nɔnɔme sia (Hypophosphatemia) ŋu!

Anɔ eme be èkpɔ nane si woyɔna be "Phosphate" ne èlé ŋku ɖe ʋu ƒe nyatakaka aɖe ŋu, alo? Alo ɖewohĩ ɖɔkta aɖe gblɔe na wò. Le nyateƒe me la, phosphate sia le vevie ŋutɔ na míaƒe ŋutilã. Eyata nukae adzɔ ne phosphate ƒe agbɔsɔsɔ sia dzi ɖe kpɔtɔ le ʋua me? Emae nye nusi míeyɔna be `(Hypophosphatemia)`. Mina míaƒo nu tso esia ŋu tsitotsito, bɔbɔe ŋutɔ, egbea.

Nukae phosphate si mebɔ o fia? Ðe wònye `(Hypophosphatemia)`?

Kpuie ko la, ẽ. Hypophosphatemia nye nɔnɔme si me mineral si woyɔna be phosphate ƒe agbɔsɔsɔ si le wò ʋu me medea ame dzi o. Phosphate nye elektrikŋusẽ si le vevie na dɔ geɖe wɔwɔ le míaƒe ŋutilã me. Ewɔa dɔ abe batri ene le míaƒe ŋutilã me. Nɔnɔme sia ate ŋu anɔ bɔbɔe alo nu sesẽ. Ate ŋu adzɔ kpata (acute) alo le ɣeyiɣi aɖe megbe (si nɔa anyi didi) hã.

Eyata aleke phosphate sia le vevie na ŋutilãa?

Bu alesi gbegbe phosphate sia wɔa dɔ le míaƒe ŋutilã me ŋu kpɔ!

• Míaƒe ƒuwo kple aɖuwo tutuɖo kple wo léle ɖe te sesĩe: phosphorus si le míaƒe ŋutilã me ƒe 85% le míaƒe ƒuwo me. Eyata esia le vevie na ƒu sesẽwo.
• Na lãmekawo nanɔ dɔ wɔm nyuie: Míaƒe lãmekawo hiã phosphate hafi woate ŋu awɔ dɔ nyuie.
• Ekpena ɖe lãmekawo ŋu be woatsi: Ne míeʋuʋu míaƒe abɔwo kple afɔwo, eye ne míaƒe dzi le ƒoƒom la, míaƒe lãmekawo hã ƒoa ƒu, eyata esia hã kpena ɖe mía ŋu le ema me.

Míekpɔa phosphorus/phosphate sia tso nuɖuɖu siwo míeɖuna me.

Vevietɔ la, phosphate ƒe agbɔsɔsɔ si le míaƒe ʋu me do ƒome kple calcium ƒe agbɔsɔsɔ tẽ. Wo ame evea wɔa dɔ le mɔ si trɔna nu. Eyae nye be ne calcium ƒe agbɔsɔsɔ le ʋua me le dzidzim ɖe edzi la, phosphate ƒe agbɔsɔsɔ dzi ɖena kpɔtɔna. Esia le dzɔdzɔm le sɛkɛnd ɖesiaɖe. Lãmetsiŋusẽ si woyɔna be parathyroid hormone (PTH), si parathyroid gland siwo le míaƒe kɔ me wɔna lae kpɔa calcium kple phosphate ƒe agbɔsɔsɔ siawo dzi.

Aleke gbegbee nɔnɔme sia bɔe (Hypophosphatemia)?

Hypophosphatemia si nu mesẽ o nye dɔléle si bɔ si wokpɔna le ʋudodokpɔwo me. Nyatakaka aɖewo ɖee fia be edzea amewo ƒe 5% dzi le United States. Zi geɖe la, menye nɔnɔme sesẽ aɖekee wònye o eye mehea dzesi aɖeke vɛ o. Zi geɖe la, woke ɖe eŋu le vo me.

Gake hypophosphatemia si nu sẽ kpata (acute, severe hypophosphatemia) bɔ ɖe amesiwo ŋu atikewɔwɔ me nɔnɔme aɖewo le la me wu. Le kpɔɖeŋu me:

• Le amesiwo ahanono zu numame na gome la `(Ahanono ƒe kuxi)`
• Le suklidɔ si do ƒome kple ketoacidosis (DKA) gome la .
• Le dɔlékui sesẽwo me la, dɔlékuiwutikewo ƒe dɔlékuiwutikewo
• Le amesiwo ƒe dzobibi gãwo gome

Woateŋu akpɔ nɔnɔme sia le ame siwo ade 80% me abe esia ene.

Eyata nukae nye `(Hypophosphatemia)` ƒe dzesiwo?

Dzesiawo nɔ te ɖe alesi phosphate ƒe agbɔsɔsɔ le sue dzi.

Hypophosphatemia si nu mesẽ o

Zi geɖe la, dzesi aɖeke menɔa amesiwo ŋu hypophosphatemia si nu mesẽ o le ŋu o , gake ame aɖewo ate ŋu akpɔ lãmekawo ƒe gbɔdzɔgbɔdzɔ vie eye ɖeɖi ate wo ŋu.

Ne esẽ ŋutɔ (Severe Hypophosphatemia) .

Gake ne phosphate ƒe agbɔsɔsɔ le sue ŋutɔ (hypophosphatemia sesẽ) la, dzesi siwo gbɔna ate ŋu ado mo ɖa, eye mele be woabu esiawo nu tsɛe o :

• Vevesese le lãmekawo kple ƒuwo me
• Lãmetsiwo ƒe gbɔdzɔgbɔdzɔ sesẽ
• Tɔtrɔ le seselelãme me - le kpɔɖeŋu me, ŋutetemanɔamesi be wòatsɔ susu aɖo nu ŋu, dzikudodo bɔbɔe
• Yagbɔgbɔ alo dzi ƒe dɔmawɔmawɔ nyuie
• Gbɔdzɔgbɔdzɔ ƒe seselelãme, ŋuɖoɖo ɖe nu ŋu dzi ɖeɖe kpɔtɔ
• Fit (alɔ̃madɔmadɔ) ƒe amesinɔnɔ .

Esia le vevie ŋutɔ: Ne womeda hypophosphatemia sesẽa kaba o , ate ŋu ana ame natsi alɔ̃ me eye wòaku gɔ̃ hã . Eyata ne dzesi sesẽ siawo le wò alo ame aɖe si nènya ŋu la, ele be nàyi kɔdzi si te ɖe ŋuwò enumake.

Ne enɔ anyi ɣeyiɣi didi aɖe (Chronic Hypophosphatemia) .

Ame siwo ƒe phosphate mesɔ gbɔ o ɣeyiɣi didi aɖe (chronic hypophosphatemia) ate ŋu akpɔ dzesiwo abe:

• Vevesese le ƒuwo me
• Ƒu ƒe gbagbã
• Gbɔdzɔgbɔdzɔ
• Nudzroame

Ðevi sue siwo me phosphate mesɔ gbɔ ɖo o le ɣeyiɣi didi aɖe me ate ŋu adze nɔnɔme aɖe si woyɔna be rickets , ƒe dzesiwo afia, siwo dometɔ aɖewoe nye:

• Kɔkɔme ƒe bu le tsitsi ta
• Afɔwo ƒe ƒoƒo abe dati ene
• Asibidɛ kple afɔkpodzi ƒe teƒewo keke le tɔtrɔ siwo va le ƒuwo me ta

Ne dzesi siawo dometɔ aɖe le ŋuwò alo viwòa ŋu la, ele vevie ŋutɔ be nàdi atikewɔlawo ƒe aɖaŋuɖoɖo.

Nukae nye nusiwo gbɔ `(Hypophosphatemia)` tsona?

Susu geɖewo li siwo tae nɔnɔme sia ate ŋu adzɔ ɖo. Nusiwo gbɔ wòtsona la toa vovo le alesi wòle bɔbɔe alo nu sẽ, kpata, alo ɣeyiɣi didi aɖee nye ema nu.

Nusiwo hea hypophosphatemia si sɔ gbɔ eye wòsẽna vɛ

Fosfate ƒe agbɔsɔsɔ si sɔ gbɔ va ɖo esi nu sẽ ate ŋu adzɔ le nɔnɔme siwo gbɔna me:

• Le suklidɔ ƒe ketoacidosis (DKA) ƒe hayahaya me .
• Ahanono kple ahanono ƒe asiɖeɖe le eŋu
• Dzobibi sesẽwo
• Refeeding syndrome : Esia sesẽ vie wu. Kpuie ko la, enye nuɖuɖu ƒe tɔtrɔ kpata le nutsitsidɔ ɣeyiɣi aɖe megbe, si hea tɔtrɔ siwo me afɔku le, siwo ate ŋu ade ame ƒe agbe afɔku me ɣeaɖewoɣi, le tsi kple elektrikŋusẽ ƒe agbɔsɔsɔ me le ŋutilãa me.
• Yagbɔgbɔ me alkalosis sesẽ: Esia nyea esime ya si woyɔna be carbon dioxide mesɔ gbɔ le ʋua me o.

Nusiwo hea hypophosphatemia si nɔa anyi didi vɛ

• Parathyroid lãmetsiŋusẽ ƒe agbɔsɔsɔ dzi ɖe edzi, le kpɔɖeŋu me le nɔnɔme si nye ``Hyperparathyroidism`` me.
• Lãmetsiŋusẽ ƒe masɔmasɔ bubuwo, abe Cushing ƒe dɔléle ene.
• Vitamin D ƒe anyimanɔmanɔ.
• Malabsorption nye nɔnɔme si me nuɖuɖu mexɔna nyuie o le nunyuimakpɔɖu kple dɔgbo ƒe kuxiwo ta.
• Elektrikŋusẽ ƒe masɔmasɔ bubuwo, abe magnesium si mebɔ o (hypomagnesemia) kple potassium si mebɔ o (hypokalemia).
• Atike si woatsɔ ada iron ƒe anyimanɔmanɔe nye iron dodo ɖe ʋu me, vevietɔ esi woyɔna be ferric carboxymaltose (FCM). Esia dzɔna zi geɖe ne wole gayibɔ nom atraɖii le mɔ sia nu.
• Aɖuɖɔtoemetikewo zazã ɣeyiɣi didi aɖe.
• Atike siwo tsia aɖi si blaa phosphate nu, siwo woƒlena le atikedzraƒe atikewɔlawo ƒe aɖaŋuɖoɖo manɔmee, zazã enuenu alo wògbɔa eme. Esia lɔ aɖitsi siwo me aluminum, calcium, kple magnesium le ɖe eme.
• Atike aɖe si woyɔna be theophylline, si wonana funɔwo ƒe aɖi.

Ame siwo ŋu ayikudɔ deŋgɔ le (vevietɔ amesiwo le ʋumenugbagbeviɣidɔ wɔm) noa atike siwo woyɔna be "phosphate binders" kpe ɖe nuɖuɖu ŋu, siwo woƒe ayikuŋutinunyala ŋlɔ na wo, be woatsɔ axe mɔ ɖe phosphate ƒe xɔxlɔ̃ tso nuɖuɖu me nu. Esiawo ate ŋu ana phosphate ƒe agbɔsɔsɔ naɖiɖi hã ne wozãe ɣeyiɣi didi.

Aleke wokpɔa nɔnɔme sia `(Hypophosphatemia)` dzea sii?

Esia didi le bɔbɔe ŋutɔ. Ðɔkta awɔ ʋudodokpɔ aɖe atsɔ akpɔe ɖa be phosphate ƒe agbɔsɔsɔ le wò ʋu me hã . Ne wò ʋu me phosphate ƒe agbɔsɔsɔ mede miligram 2.5 le deciliter ɖeka me (mg/dL) o la, wogblɔna be ``Hypophosphatemia'' le ŋuwò.

Fosfate ƒe agbɔsɔsɔ si sɔ le ʋu me na ame tsitsiwo le 2.5 va ɖo 4.5 mg/dL, eye le ɖeviwo gome la, ele 4.5 va ɖo 6.5 mg/dL dome. Gake asixɔxɔ siawo ate ŋu ato vovo vie tso dodokpɔxɔ ɖesiaɖe me.

Le go geɖe me, vevietɔ le phosphatemia si nu sẽ ŋutɔ gome la, woate ŋu anɔ te ɖe wò atikewɔwɔ ŋutinya kple dzesiwo dzi ade dzesi nusi gbɔ wòtso nyuie.

Esi wònye be zi geɖe la, atikewɔwɔ ƒe nɔnɔme bubu aɖe gbɔe phosphatemia ƒe agbɔsɔsɔ si medea ame dzi o tsona ta la, wò ɖɔkta ate ŋu aɖe gbe be woawɔ dodokpɔ bubuwo atsɔ anya nusi gbɔ wòtso eye woada wò lãmesẽ bliboa kpɔ. Esiawo ate ŋu anye:

• Ʋudodokpɔ bubuwo: Ayiku ƒe dɔwɔwɔ dodokpɔ, calcium ʋudodokpɔ, vitamin D ƒe ʋudodokpɔ.
• Aɖuɖɔtoe me dzodzro.
• Ðewohĩ nɔnɔmetatawo ƒe fotoɖeɖe.

Nukae nye atikewɔwɔ na `(Hypophosphatemia)`?

Atikewɔwɔ vevitɔe nye be woada nusi gbɔ nɔnɔme sia tsona, eye woagagbugbɔ phosphate ƒe agbɔsɔsɔ si le ʋua me aɖo eteƒe.

Zi geɖe la , wonaa atikekui siwo woano atsɔ aɖɔli phosphate . Ðewohĩ wò ɖɔkta aɖo aɖaŋu na wò hã be nàɖu nuɖuɖu siwo me phosphorus sɔ gbɔ ɖo.

Gake ne dɔlélea nu sẽ la, wodoa phosphate ɖe ʋuka me (to IV dzi) .

Ðe nane li míate ŋu awɔ atsɔ axe mɔ ɖe nɔnɔme sia nua?

Nyateƒee, menye hypophosphatemia ƒe dɔlélewo katãe woate ŋu axe mɔ na o, vevietɔ esiwo nu sẽ eye wodzɔna kpata. Gake nuɖuɖu si naa lãmesẽ, si da sɔ ɖuɖu ate ŋu awɔ akpa aɖe le mɔxexe ɖe phosphate ƒe agbɔsɔsɔ si nu mesẽ o nu.

Nuɖuɖu kawoe me phosphorus sɔ gbɔ ɖo?

• Lã, tɔmelã kple protein bubuwo: Akpa aɖewo abe azi, koklozi, koklozi, haƒoƒo, ƒumelãwo, kple aklã ene.
• Notsi me nuɖuɖuwo: notsi, cheese, cottage cheese, yogurt.
• Nukuwo kple nukuwo: almond, cashew, Brazil nukuwo, mɔli nukuwo, sesame nukuwo.

Vevietɔ: Hafi nàwɔ tɔtrɔ gã aɖe le wò nuɖuɖu ŋu la, kpɔ egbɔ be yeƒo nu kple ɖɔkta alo nuɖuɖuŋutinunyala.

Ne dɔléle aɖe le ŋuwò si na nèle afɔku gã aɖe me be nàxɔ hypophosphatemia, abe hyperparathyroidism, malabsorption ƒe nyawo, alo vitamin D ƒe anyimanɔmanɔ ene la, ele vevie be nàkpɔ wò ɖɔkta edziedzi eye nàwɔ ɖe wò atikewɔwɔ ƒe ɖoɖoa dzi. Esia ate ŋu akpe ɖe ame ŋu be woaxe mɔ ɖe hypophosphatemia nu.

Nukae adzɔ le etsɔme? (Nyagblɔɖi) .

Nɔnɔme sia ƒe ŋgɔdonya nɔ te ɖe nenye be mesẽ alo nu sẽ o, ne edze egɔme kpata, alo exɔ ɣeyiɣi didi aɖe dzi. Zi geɖe la, dɔlékui siwo mesẽ o wɔa dɔ nyuie ne wowɔ atike na wo, si fia be woate ŋu ada wo. Gake dɔléle sesẽ siwo dzea egɔme kpata ate ŋu ahe kuxi sesẽwo vɛ ne womeda wo kaba o.

Ðe kuxiwo ate ŋu ado mo ɖa le `(Hypophosphatemia)` ta?

Ẽ, ne womewɔ atike nɛ o, vevietɔ ne phosphate dzi ɖe kpɔtɔ ɣeyiɣi didi aɖe (chronic hypophosphatemia) la, dɔléle aɖe si woyɔna be osteomalacia ate ŋu adze ame dzi. Kpuie ko la, ɣeyiɣi sia mee ƒuawo fa eye wogbãna bɔbɔe .

Abe alesi míegblɔe va yi ene la, ne hypophosphatemia ƒe dzesi sesẽwo le ŋuwò, abe lãmekawo ƒe vevesese si womenya o kple susu ƒe nɔnɔme ƒe tɔtrɔ ene la, ele vevie ŋutɔ be nàyi kɔdzi si te ɖe ŋuwò kaba ale si nàte ŋui.

Mlɔeba la, ɖo ŋku esia dzi.

Eyata, phosphate sia si ŋu míeƒo nu tsoe egbea nye ``electrolyte`` vevi aɖe ŋutɔ le míaƒe ʋu me. Woateŋu akpɔ phosphate ƒe ɖiɖi vie (``mild hypophosphatemia``) le ʋudodokpɔ me eye menye nusi ŋu woatsi dzi ɖo o. Ne edzɔ alea la, wò ɖɔkta agblɔ na wò be nàɖu nuɖuɖu siwo me phosphorus sɔ gbɔ ɖo wu.

Gake ne dɔléle aɖe le ŋuwò alo numame aɖe le ŋuwò si na nèle afɔku me be phosphate ƒe agbɔsɔsɔ si mede ame dzi o vevie, abe aha sesẽ nono fũ alo dɔgbo ƒe dɔmawɔmawɔ nyuie ene la, anyo wu be nàƒo nu tso eŋu na wò ɖɔkta. Bia wo alesi woawɔ axe mɔ ɖe hypophosphatemia nu kple dzesi siwo ŋu wòle be woakpɔ nyuie le. Ðo ŋku edzi be wò ɖɔktae nye xɔ̃wò vevitɔ le wò lãmesẽmɔzɔzɔa me. Woate ŋu akpe ɖe ŋuwò.

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