Ðe viwòa tsi megbe le sɔhɛmenɔɣia? Ðe ʋeʋẽse gɔ̃ hã mele esi oa? Ðe wòate ŋu anye Kallmann ƒe Dɔlélea?

Togbɔ be viwòa tsi vie hã la, ɖe meɖea sɔhɛmenɔɣi ƒe dzesiwo fiana abe exɔlɔ̃wo ene oa? Alo ède dzesii be mesea ʋeʋẽ aɖewo ŋutɔŋutɔ o, le kpɔɖeŋu me, seƒoƒo alo nuɖuɖu ƒe ʋeʋẽa? Nu siawo tɔgbi ate ŋu ahe dzimaɖitsitsi kple dzimaɖitsitsi vi aɖe vɛ le míaƒe susu me abe dzilawo ene. Esia tae, egbea míele nu ƒom tso nɔnɔme aɖe si ɖea dzesi siawo fiana, gake womeƒoa nu tso eŋu boo le hadomegbenɔnɔ me o, gake ele vevie ŋutɔ be woanya eŋu. Ema nye nɔnɔme aɖe si woyɔna be Kallmann Syndrome .

Nukae nye Kallmann ƒe Dɔléle sia?

Kpuie ko la, Kallmann Dɔléle nye domenyiŋusẽfianu ƒe dɔléle si mebɔ o . Nu vevitɔ si dzɔna le esia mee nye be ɖevi ƒe sɔhɛmenɔɣi tsia megbe ŋutɔ . Le go aɖewo me la, sɔhɛmenɔɣi ate ŋu adzudzɔ kura. Tsɔ kpe ɖe eŋu la, ame geɖe siwo ŋu dɔléle sia le la ƒe ʋeʋẽse dzi ɖena kpɔtɔna ŋutɔ alo megate ŋu sea nu keŋkeŋ o . Míeyɔa esia hã be ``anosmia'' le atikewɔwɔ me.

Nusitae nɔnɔme sia le enye be ne ɖevia gakpɔtɔ le vidadaa ƒe dɔ me la, tɔtrɔ aɖewo va le domenyiŋusẽfianu aɖewo siwo do ƒome kple eƒe ŋutilã ƒe tsitsi me. Bu eŋu abe vodada sue aɖe si le kɔmpiutadziɖoɖo aɖe me ene. Ɣeaɖewoɣi la, woate ŋu anyi domenyiŋusẽfianu ƒe tɔtrɔ siawo ƒe dome tso dzilawo gbɔ na ɖeviwo. Eyae nye be ɖevia xɔa domenyiŋusẽfianu sia tso vidadaa alo fofoa gbɔ. Gake le go aɖewo me la, ɖɔktawo gblɔna be domenyiŋusẽfianu ƒe tɔtrɔ siawo ate ŋu adzɔ le vome, eye ƒome ŋutinya aɖeke mekɔ o.

Nɔnɔme sia bɔ ɖe ŋutsuviwo me wu nyɔnuviwo. Zi geɖe la, dzilawo kple ɖɔktawo léa ŋku ɖe eŋu wu ne ɖevi ƒe sɔhɛmenɔɣi tsi megbe le mɔ si mebɔ o nu. Eyata zi geɖe la, wokpɔa Kallmann Dɔlélea le ƒe 8 va ɖo ƒe 15 dome.

Ðɔktawo zãa ŋkɔ bubu na nɔnɔme sia ɣeaɖewoɣi, si nye ``hypogonadotropic hypogonadism'' . Togbɔ be esia aɖi nya sesẽ vie hã la, ɖeko wòfia be ŋutsuviwo ƒe vidzidɔ kple nyɔnuviwo ƒe azigolowo mewɔa gbɔdɔdɔ ƒe lãmetsi siwo hiã vevie na sɔhɛmenɔɣi kple gbɔdɔdɔ ƒe dɔwɔwɔ wòsɔ gbɔ o. Ðe wòxɔea? Efia be lãmetsiŋusẽ ƒe dɔmawɔmawɔ nyuie ƒomevi aɖe le lãmetsiŋusẽ ƒe dɔwɔwɔ me.

Nukawoe nye Kallmann ƒe dɔlélea ƒe dzesiwo?

Azɔ mina míakpɔ dzesi siwo ame si ŋu Kallmann Syndrome le la ɖena fiana ɖa. Woate ŋu akpɔ dzesi siawo dometɔ aɖewo le ɖevime, eye ɖewo ate ŋu adze le ame tsitsi megbe gɔ̃ hã. Menye amesiamee akpɔ dzesi ɖeka o.

Nu vevitɔe nye nɔnɔme siwo do ƒome kple sɔhɛmenɔɣi:

• Le nyɔnuviwo gome la, no ƒe tsitsi menɔa anyi kura o alo mebɔ kura o .
• Le nyɔnuviwo gomeÐewohĩ dzinukpɔkpɔ (dzinukpɔkpɔ) madzɔ kura o, alo ate ŋu adzɔ emegbe kura wu alesi wòle dzɔdzɔmee eye medzɔna edziedzi o.
• Ŋutsuviwo ƒe vidzinu kple vidzidɔ le sue wu alesi wòle dzɔdzɔmee .
• Vidzidzi ƒe ŋutete dzi ɖeɖe kpɔtɔ alo vidzidzi ƒe ŋutete si le ŋutsuwo kple nyɔnuwo siaa si le tsitsime.

Tsɔ kpe ɖe eŋu la, nu bubu siwo woate ŋu akpɔ:

• Ʋeʋẽ ƒe ŋutete ƒe bu keŋkeŋ (anosmia) alo ʋeʋẽ ƒe ŋutete si dzi ɖe kpɔtɔ ŋutɔ nye Kallmann ƒe dɔlélea ƒe nɔnɔme bubu.
• Ame aɖewo ate ŋu akpɔ dadasɔ ƒe kuxiwo ne wole zɔzɔm alo le tsitrenu .
• Ƒã ŋutɔ la, ate ŋu anye be aɖu me ʋuʋu , si nye ʋuʋudedi si wodzina le aɖu si le etame.
• Aɖukuxiwo , le kpɔɖeŋu me, aɖu siwo bu alo aɖu siwo le sue le mɔ si mebɔ o nu (aɖu ƒe dɔmawɔmawɔ nyuie).
• Ŋku ƒe ʋuʋu ƒe kuxiwo , abe nystagmus ene, si nye nɔnɔme si me ŋkuwo ʋãna kabakaba eye womate ŋu aɖu wo dzi o.
• Ðeɖiteameŋu si gbɔ eme ƒe seselelãme ɣesiaɣi (Ðɖiteameŋu) .
• Nyɔnuwo ƒe dzinukpɔkpɔ medzɔna edziedzi o .
• Gbɔdɔdɔ ƒe dzodzro si mebɔ o .
• Nɔnɔme ƒe tɔtrɔ kpata , si kpena ɖe dzimaɖitsitsi, blanuiléle, kple dziku ƒe seselelãme enuenu ŋu.
• Ƒã ŋutɔ la, wole nɔnɔme aɖe si woyɔna be ``Renal agenesis`` dzim ayiku ɖeka manɔmee .
• Ame aɖewo ƒe akɔta ƒuna (Scoliosis) .
• Kpekpeme dzi ɖeɖe kpɔtɔ susu aɖeke si me kɔ o .

Nu vevitɔe nye be menye amesiamee dzesi siawo katã le o. Ame aɖewo gɔ̃ hã ate ŋu abu nuʋeʋẽse. Le nɔnɔme siawo tɔgbe me la, ɖɔktawo yɔa nɔnɔmea be ``normosmic idiopathic hypogonadotropic hypogonadism (nIHH)``. Esia fia be ʋeʋẽse ƒe ŋutete sɔ, gake lãmetsiŋusẽ ƒe kuxia ya le afima.

Nukatae nɔnɔme sia dzɔna ɖo?

Enyo, fifia ɖewohĩ èle eŋu bum be, ‘Nukatae esia dzɔna? Nukae nye nusi gbɔ wòtso?’ Nusi koŋ gbɔ Kallmann ƒe Dɔlélea tsonae nye tɔtrɔ alo gbɔdzɔgbɔdzɔ aɖewo le domenyiŋusẽfianu aɖewo me le míaƒe ŋutilã me . Tɔtrɔ siawo gblẽa nu sesẽ siwo kpɔa ɖevi ƒe sɔhɛmenɔɣi dzi, siwo dzea egɔme tso ahɔhɔ̃a me.

Zi geɖe la, sɔhɛmenɔɣi ƒe ɖoɖo sia dzea egɔme tso lãkusi vevi aɖe ŋutɔ le ɖevia ƒe ahɔhɔ̃ me si woyɔna be hypothalamus, si ɖea lãmetsi si nye Gonadotropin-Releasing Hormone (GnRH) dona.Le atike aɖe si woyɔna be. Bu eŋu kpɔ be `(GnRH)` sia le abe ``master switch`` si dzea sɔhɛmenɔɣi ƒe ɖoɖo bliboa gɔme ene. Le ɖevi si ŋu Kallmann ƒe dɔlélea le gome la, hypothalamus mewɔa `(GnRH)` lãmetsi sia wòsɔ gbɔ o, alo ɖewohĩ mewɔe kura o. Eyata, esi ``master switch`` ma mele ``on`` o ta la, sɔhɛmenɔɣi ƒe ɖoɖoa medzea egɔme nyuie o.

Lãmetsi sia `(GnRH)` ye kpena ɖe gbɔdɔdɔ ƒe tsitsi, gbɔdɔdɔ ƒe dzodzro, kple ŋutete be woadzi vi le etsɔme (vidzidzi) ŋu. Lãmetsi sia toa ʋukawo me yia pituitary gland, si nye lãkusi vevi bubu le ahɔhɔ̃a me. Emegbe `(GnRH)` lãmetsiŋusẽa naa dzesi na pituitary gland be wòawɔ lãmetsiŋusẽ eve bubuwo. Woawoe nye:

• Lãmetsiŋusẽ si doa ŋusẽ lãkusi (FSH) .
• Lãmetsiŋusẽ si naa luteinizing (LH) .

Lãmetsi eve siawo, `(FSH)` kple `(LH)`, yia nyɔnuviwo ƒe azigolowo kple ŋutsuviwo ƒe vidzidɔwo me tẽ, si kpena ɖe wo ŋu wowɔa gbɔdɔdɔ ƒe lãmetsiwo (abe estrogen kple testosterone ene) eye wònana wotsia gbɔdɔdɔ me. Eyata, le `(GnRH)` ƒe anyimanɔmanɔ me la, kɔsɔkɔsɔ blibo sia gblẽna.

Nusitae ʋeʋẽ ƒe anyimanɔmanɔ hã do ƒome kple domenyiŋusẽfianu ƒe tɔtrɔ siawo. Domenyiŋusẽfianu ƒe tɔtrɔ aɖewo hã kpɔa ŋusẽ ɖe ɖevia ƒe ahɔhɔ̃ ƒe ʋeʋẽ ƒe ŋutete dzi. Zi geɖe la, ʋeʋẽ ƒe lãmenugbagbevi siwo le míaƒe ŋɔti me dea dzesi ʋeʋẽ vovovowo eye woɖoa nyatakaka mawo ɖe ʋeʋẽ ƒe ʋuƒo si le ahɔhɔ̃a me (ahɔhɔ̃a ƒe akpa si kpɔa ʋeʋẽ dzi). Le Kallmann ƒe dɔlélea me la, kuxi aɖe le ʋeʋẽ ƒe lãmeka siawo ƒe tsitsi alo woƒe kadodo kple ahɔhɔ̃a ŋu. Esia wɔe be dzesi siwo ku ɖe ʋeʋẽ ŋu meɖoa ahɔhɔ̃a gbɔ nyuie o.

Aleke domenyiŋusẽfianu ƒe ŋusẽkpɔɖeamedzia le?

Fifia numekulawo de dzesi domenyiŋusẽfianu ƒe tɔtrɔ siwo wu 25 siwo hea Kallmann ƒe dɔléle kple ``hypogonadotropic hypogonadism'' nɔnɔme bubuwo vɛ. Esia fia be anɔ eme be domenyiŋusẽfianu siwo wu ɖeka gbɔe nɔnɔmea tso. Le esiawo dome la, wokpɔe be domenyiŋusẽfianu geɖe do ƒome kple nɔnɔmea vevie wu:

• `KAL1 (ANOS1)`
• `CHD7`
• `FGFR1`
• `GNRHR`
• `IL17RD`
• `PROK2`
• `SOX10`
• ``TACR3''.

Domenyiŋusẽfianu ƒe tɔtrɔ siawo dzɔna le fugboe ƒe nɔnɔme me, si fia be ne ɖevia gakpɔtɔ le vidadaa ƒe dɔ me. Ɣeaɖewoɣi la, tɔtrɔ siawo ate ŋu adzɔ le vome, susu aɖeke manɔmee. Gake le go geɖe me la, woate ŋu anyi tɔtrɔ siawo ƒe dome tso dzilawo gbɔ va ɖo ɖeviwo gbɔ.

Mɔ vovovowo li siwo dzi domenyiŋusẽfianu ƒe tɔtrɔ siawo tona yia ɖeviwo dzi. Míeyɔa domenyinu ƒe ɖoɖo siawo be :

• Autosomal recessive inheritance: Le go sia me la, dzila evea siaa nye domenyiŋusẽfianu ƒe tɔtrɔ la tsɔlawo (si fia be dzesi aɖeke mele wo ŋu o, gake domenyiŋusẽfianu si gblẽ le wo ŋu). Hafi nɔnɔme sia nadze ɖevi dzi la, ele be dzila evea siaa nanyi domenyiŋusẽfianu si gblẽ la ƒe kɔpi eveawo siaa dome.
• Autosomal dominant inheritance: Nɔnɔme sia ate ŋu ado mo ɖa ne ɖevia nyi domenyiŋusẽfianu si gblẽ la ƒe kɔpi ɖeka tso dzila ɖeka (dadaa alo fofoa) gbɔ gɔ̃ hã.
• Domenyinu si do ƒome kple X: Le go sia me la, domenyiŋusẽfianu si gblẽ la le X domenyiŋusẽfianu dzi. Esia ate ŋu agblẽ nu le ŋutsuwo ŋu wu.

Togbɔ be esiawo nye atikewɔwɔ me nyateƒenya siwo de to vie hã la, mesusu be wole vevie be woakpɔ alesi woate ŋu ato domenyiŋusẽfianuwo dzi ato nɔnɔme sia me tso dzidzime yi dzidzime dzi la ŋuti nukpɔsusu si me kɔ.

Kuxi kawoe esia ate ŋu ahe vɛ?

Ðevi ƒe sɔhɛmenɔɣi nye nu vevi aɖe ŋutɔ le woƒe ŋutilã kple susu ƒe tsitsi me. Kallmann ƒe Dɔléle ate ŋu axe mɔ na ɖevi be wòagaɖo nu vevi ma gbɔ abe alesi wokpɔ mɔe ene o. Esia fia be ɖevia ƒe gbɔdɔdɔ ƒe tsitsi ate ŋu ahe ɖe megbe ne wotsɔe sɔ kple ɖevi bubu siwo xɔ ƒe ma ke, alo ate ŋu adzudzɔ kura gɔ̃ hã.

Bu eŋu kpɔ, ne ɖevi sue aɖe le exɔlɔ̃ bubu siwo nye eƒe ƒemetɔwo gbɔ la, aleke gbegbe wòasesẽe be woakpɔe be yewo xɔlɔ̃wo ƒe ŋutilã le tɔtrɔm (abe alesi wole kɔkɔm ɖe edzi, woƒe gbe le tɔtrɔm, woƒe ɖa le tsitsim, woƒe nowo le tsitsim ene), gake woawo tɔ ya mele tɔtrɔm o? Ðewohĩ ŋu akpe wo eye be yewobɔbɔ ɖe anyi le yewoƒe dzedzeme ta. Woate ŋu ase le wo ɖokui me be yewoto vovo eye yewoɖe yewo ɖokui ɖe aga tso ame bubuwo gbɔ. Le nu siawo tɔgbe ta la, ɖevia ate ŋu axɔ susu me kuxiwo abe blanuiléle alo dzimaɖitsitsi vevie ene . Ate ŋu asesẽ be woawɔ nu kple ame bubuwo le suku kple le hadome.

Eyata ele vevie ŋutɔ be woawɔ ŋutilãmedɔ na ɖevi si ŋu dɔléle sia le, eye woakpɔ woƒe susu ƒe lãmesẽ dzi hã, eye woaɖo aɖaŋu na wo ne ehiã . Dzilawo kple nufialawo ƒe kpekpeɖeŋu hã xɔ asi ŋutɔ le afisia.

Aleke ɖɔktawo wɔna kpɔa esia?

Zi geɖe la, ne ètsi dzi ɖe viwò ƒe tsitsi ŋu, le kpɔɖeŋu me, ne womedze sɔhɛmenɔɣi ƒe dzesiwo ɖeɖefia gɔme hafi wòxɔ ƒe 13-14 o la, àyi ɖeviwo ƒe dɔdala gbɔ gbã. Alo àte ŋu ayi lãmenugbagbeviwo ƒe dɔwɔwɔ ŋuti nunyala hã gbɔ.

Nu gbãtɔ si ɖɔktaa wɔnae nye be wòdoa ɖevia ƒe ŋutilã kpɔ nyuie . Eyae nye be woléa ŋku ɖe ame ƒe kɔkɔme, kpekpeme, kple sɔhɛmenɔɣi ƒe dzesiwo (abe no ƒe tsitsi kple vidzinuwo ƒe tsitsi ene) ŋu. Emegbe wobiaa ɖevia kple wò (dzilawo) tso ŋutilã me tɔtrɔ siwo ɖeviwo kpɔna zi geɖe ne woxɔ tso ƒe 8 va ɖo ƒe 15. Woate ŋu abia hã nenye be ƒomea me tɔ aɖe tsi ƒewuiwo me alo meto sɔhɛmenɔɣi kura o hã. Woabia hã be kuxi aɖe le ʋeʋẽse ŋu hã.

Emegbe ne ɖɔktaa susui be Kallmann ƒe Dɔlélea le eŋu la, ate ŋu aɖo aɖaŋu be woawɔ dodokpɔ geɖe, abe:

• Ʋudodokpɔ:Esiawo nye dodokpɔ vevitɔwo dometɔ ɖeka. Woléa ŋku ɖe lãmetsi vovovo siwo le ŋutilãa me ƒe agbɔsɔsɔ ŋu. Etɔxɛe la, lãmetsi siwo le lãkusi me siwo ŋu míeƒo nu tsoe va yi, siwo woyɔna be FSH kple LH, kple gbɔdɔdɔ ƒe lãmetsi siwo nye testosterone (le ŋutsuviwo me) kple estrogen (le nyɔnuviwo me). Zi geɖe la, lãmetsi siawo ƒe agbɔsɔsɔ medea ame dzi le Kallmann ƒe dɔlélea me o.
• Dodokpɔ siwo wowɔna tsɔ léa ŋku ɖe ʋeʋẽ ƒe ŋutete ŋu: Dodokpɔ bɔbɔe aɖee nye esia. Wonaa ʋeʋẽ vovovo siwo wonya nyuie ɖevia (e.g. kɔfi, adzalẽ, mint) eye wobia tso esi be wòade dzesi wo.
• Domenyiŋusẽfianu dodokpɔ: Esia bia be woadi domenyiŋusẽfianu ƒe tɔtrɔ tɔxɛ aɖewo le ʋu aɖe si ŋu míeƒo nu tsoe va yi me siwo do ƒome kple Kallmann ƒe dɔlélea. Gake menye ɣesiaɣie wowɔa dodokpɔ siawo o eye woate ŋu axɔ asi vie. Ne ehiã ko hafi wowɔa wo, le dodokpɔ bubuwo wɔwɔ vɔ megbe.
• Ɣeaɖewoɣi la, woate ŋu awɔ ahɔhɔ̃a ƒe MRI-dɔdamɔnu be woakpɔe ɖa be kuxi aɖewo le hypothalamus kple pituitary glands ŋu hã, alo ne ʋeʋẽse ƒe lãkusia metsi o hã.

Ðe atikewɔmɔnu aɖewo lia?

Dzɔgbenyuietɔe la, atike nyuiwo li na Kallmann Dɔlélea. Atikewɔwɔ vevitɔe nye lãmetsiŋusẽtikewo ɖɔliɖɔli (HRT) . Esia bia be woana lãmetsi siwo ŋutilãa mele wɔwɔm le dzɔdzɔme nu o alo le wɔwɔm le agbɔsɔsɔ sue aɖe me. Mɔkpɔkpɔae nye be atikewɔwɔ siawo akpe ɖe ame ŋu wòadze sɔhɛmenɔɣi gɔme, atu gbɔdɔdɔ ƒe nɔnɔme evelia (abe mo ƒe fu kple no ƒe tsitsi ene), eye wòado ŋusẽ ƒuwo.

Gake atikewɔwɔ kple lãmetsiŋusẽ ƒomevi siwo woana ate ŋu ato vovo tso ame ɖeka gbɔ yi bubu gbɔ, le ŋutsuvi alo nyɔnuvi si ɖevia nye, kple ƒe si wòxɔ nu.

Dɔdamɔnu siwo wozãna wu dometɔ aɖewoe nye esi:

• Le ŋutsuviwo gome: Testosterone ye nye lãmetsi si wonana. Woate ŋu adoe abe atike si wodona ɖe lãme na ame ene (anɔ abe zi ɖeka le ɣletia me ene), abe ŋutigbalẽ ƒe atike ene, alo abe ŋutigbalẽ ƒe atike siwo wodona gbesiagbe ene .
• Le nyɔnuviwo gome: Wonaa estrogen gbã. Emegbe la, wotsɔnɛ tsakana kple progesterone be wòana dzinukpɔkpɔ nadze. Woate ŋu ana esiawo abe atikekuiwo ene alo abe ŋutigbalẽtikewo ene.
• Ɣeaɖewoɣi, vevietɔ le ame tsitsi siwo le ɖoɖo wɔm be yewoadzi vi gome la, woate ŋu ana atikewɔwɔ kple GnRH lãmetsiŋusẽ ƒe pɔmpi alo lãmetsi siwo sɔ kple FSH kple LH, abe HCG (amegbetɔ ƒe chorionic gonadotropin) kple hMG (amegbetɔ ƒe dzinukpɔkpɔ ƒe gonadotropin) ene dodo be woatsɔ aʋã fugboe (le nyɔnuwo me) alo tsinyenye ƒe wɔwɔme (le ŋutsuwo me).

Ne ɖɔktaa dze atikewɔwɔ sia gɔme vɔ la, ado ɖevia kpɔ edziedzi, alé ŋku ɖe lãmetsiŋusẽ ƒe agbɔsɔsɔ ŋu, eye wòatrɔ asi le atikewɔwɔ ƒe agbɔsɔsɔme ŋu ne ehiã.

Nukae nàte ŋu akpɔ mɔ na ne èle agbe kple nɔnɔme sia?

Ðewohĩ ahiã be ɖevi si ŋu dɔléle sia le nano lãmetsiŋusẽtikewo le woƒe agbemeŋkekewo katã me alo ɣeyiɣi didi aɖe . Emae nye nɔnɔme si sɔ.

Gake nya nyuiae nye be ŋutsu kple nyɔnu siwo ŋu Kallmann ƒe dɔlélea le siaa ate ŋu agadzi vi ne wozã lãmetsiŋusẽtike si sɔ. Atikewɔwɔ tɔxɛ aɖewo li na esia. Ŋutsu aɖewo ate ŋu ayi edzi anɔ tsinyenye dzim ne wodzudzɔ atikewɔwɔ vɔ. Ðɔktawo yɔa esia be ‘Kallmann ƒe dɔléle si woate ŋu atrɔ’ . Gake esia medzɔna ɖe amesiame dzi o.

Tsitsi kple ƒewuiwo me yiyi nye ɣeyiɣi si me kuxi geɖe le agbe me. Kallmann Syndrome ƒe amesinɔnɔ ate ŋu ana kuxi ma nalolo ɖe edzi. Esia ate ŋu ana sɔhɛmenɔɣi nahe ɖe megbe, alo sɔhɛmenɔɣi kura gɔ̃ hã. Eyata ne dɔléle sia le viwòa ŋu la, ɖewohĩ ŋutilã me tɔtrɔ siwo wo hatiwo kpɔna la makpɔ o. Esia ate ŋu ana woatsi dzimaɖi ɖe woƒe dzedzeme ŋu, ŋu nakpe wo, eye woadze agbagba aɖe wo ɖokui ɖa tso ame bubuwo gbɔ. Woate ŋu ase le wo ɖokui me be wole yewo gblẽm ɖi, alo be yewoto vovo.

Ne womeɖo ŋkeke alo ɣeyiɣi aɖeke ɖi na viwòa ƒe sɔhɛmenɔɣi o hã la, ne nyabiase alo dzimaɖitsitsi aɖewo le asiwò ku ɖe viwòa ƒe tsitsi ŋu, vevietɔ gbɔdɔdɔ ƒe tsitsi ŋu la, nu nyuitɔ si nàwɔe nye be nàƒo nu kple ɖeviwo ƒe dɔdala alo lãmetsiŋusẽŋutinunyala bibi aɖe . Woate ŋu ada mia kple viwòa kpɔ nyuie eye woana mɔfiame kple atikewɔwɔ si hiã.

Gbedasi si Wotsɔ Yi Aƒeme

Enyo, eyata le nusiwo ŋu míeƒo nu tsoe didi nu la, mele mɔ kpɔm be susu nyui aɖe si me kɔ la va su asiwò ku ɖe Kallmann Dɔlélea ŋu.

Kpuie ko la, Kallmann ƒe dɔlélea nye domenyiŋusẽfianu ƒe dɔléle si mebɔ o si koŋ hea sɔhɛmenɔɣi ɖe megbe eye zi geɖe la, enaa ʋeʋẽse hã buna.

• Kuxi vevitɔ si le esia mee nye lãmetsiŋusẽ ƒe kɔsɔkɔsɔ si dzea egɔme tso ahɔhɔ̃a me.
• Nɔnɔme sia ate ŋu adze ŋutsuwo kple nyɔnuwo siaa dzi , gake ebɔ ɖe ŋutsuviwo me wu.
• Dzesiawo ate ŋu anye nusiwo le abe sɔhɛmenɔɣi ƒe dzesiwo maɖemaɖe le ƒe si sɔ me o, ʋeʋẽse ƒe ŋutete ƒe bu alo dzi ɖeɖe kpɔtɔ, aɖu ƒe kuxiwo, kple ŋku ƒe ʋuʋu ƒe kuxiwo ene.
• Lãmetsiŋusẽ ƒe atikewɔwɔe nye atikewɔwɔ vevitɔ. Ðewohĩ atikewɔwɔ sia ahiã le agbemeŋkekewo katã me.
• Zi geɖe la , atikewɔwɔ ate ŋu ana ame naɖo sɔhɛme eye wòana vidzidzi ƒe ŋutete nagaɖo ame ŋu .
• Susuŋutinunya ƒe kpekpeɖeŋu kple aɖaŋuɖoɖo hã le vevie ŋutɔ na ɖeviwo kple ame tsitsi siwo ŋu dɔléle sia le.
• Ne ɖikeke aɖe le mewò le viwòa ƒe sɔhɛmenɔɣi ŋu la, mègahe ɖe megbe aɖakpɔ ɖɔkta o . Zi alesi wokpɔe kaba la, zi nenemae wònɔa bɔbɔe be woadze atikewɔwɔ gɔme eye woaɖe kuxi siwo ate ŋu ado mo ɖa dzi akpɔtɔ.

Míele mɔ kpɔm vevie be nyatakaka siawo kpe ɖe ŋuwò. Ðo ŋku edzi be menye wò ɖeka koe le mɔzɔzɔ sia me o. Ðɔkta kple aɖaŋuɖola bibiwo le Sri Lanka be woakpe ɖe amesiwo dze ŋgɔ nɔnɔme mawo tɔgbe ŋu ahafia mɔ wo.

Kallmann Dɔléle, sɔhɛmenɔɣi ƒe megbetsitsi, ʋeʋẽse ƒe ŋutete ƒe bu, anosmia, lãmetsiŋusẽ ƒe kuxiwo, domenyiŋusẽfianu ƒe dɔlélewo, hypogonadotropic hypogonadism