Ðe histamine gbɔe tɔtrɔ siawo siwo vaa wò ŋutilã me tsona? Mina míakpɔe ɖa godoo!

Ðe wòsena le ɖokuiwò me zi ɖeka be yeƒe lãme gbãa? Ðe nèɖea aɖuɖɔ le aɖuɖɔ vɔ megbea? Alo ɖe wò ŋutilã xɔa abi le ɣeyiɣi aɖe megbe le nuɖuɖu aɖewo ɖuɖu vɔ megbea? Anɔ eme be nu siawo dzɔ ɖe dziwò hã. Zi geɖe la, woyɔa amesi le megbe na vevesese siawo be histamine. Egbea, mina míaƒo nu tso nusi histamine nye, nusita wòle vevie na míaƒe ŋutilã, kple nusi dzɔna ne edzi ɖe edzi ŋu.

Nuka tututue nye histamine?

Kpuie ko la, histamine nye atike si nɔa míaƒe ŋutilã me le dzɔdzɔme nu. Ele abe dɔla sue aɖe si wɔa dɔ le míaƒe ŋutilã me ene. Wodzrae ɖo ɖe lãmenugbagbevi aɖewo me le míaƒe ŋutilã me. Wodzrae ɖo ɖe lãmenugbagbevi ƒomevi eve siwo woyɔna be mast cells kple basophils me koŋ. Lãmenugbagbevi siawo nye míaƒe dɔlélenutsiŋutete, si nye nuɖoanyi si kpɔa mía ta tso dɔlélewo me la ƒe akpa aɖe. Bu eŋu abe mɔ̃ sesẽ ene. Ne futɔ aɖe (le kpɔɖeŋu me, dɔlékui alo aŋɔ) tso mɔ̃ sesẽ sia godo la, dzɔla siwo le abe mast cell siawo ene zãa aʋawɔnu aɖe si woyɔna be histamine tsɔ dzea aʋawɔwɔa gɔme. Menye ema ɖeɖeko o, ke xɔlɔ̃ sia si woyɔna be histamine hã kpɔa gome le kpekpeɖeŋu nana míaƒe dɔgbo be wòaɖu nuɖuɖu kple ahɔhɔ̃a ƒe dɔwɔwɔ aɖewo hã me.

Nukatae histamine sia dona le míaƒe ŋutilã me?

Susu vevitɔ si ta histamine dona le ŋutilãa mee nye nulɔdɔwo . Na míakpɔ ale si wòdzɔnae ɖa. 1. Nulɔdɔ: Tsɔe be ke ƒe nulɔdɔ le ŋuwò. Ne èyi teƒe si ke le la, ke mawo (siwo míeyɔna be allergens ) gena ɖe wò ŋɔti me. Emegbe mast cells siwo le míaƒe ŋutilã me dea dzesi ke siawo be wonye "futɔ". Wodea dzesi wo eye wodzea nuwɔwɔ ɖe wo ŋu gɔme. Le ɣeyiɣi sia me la, histamine si le mast cells me la dona zi ɖeka. Abe bɔmb si le wóm ene. Histamine siae nana aɖuɖɔɖɔɖɔ, ŋɔti me tsi, eye ŋkuwo ʋuʋuna.

• Nusiwo nana ame ƒe ŋutilã mewɔa dɔ nyuie o dometɔ aɖewoe nye:
• Pollen si woyɔna be Pollen
• Ke ƒe ʋuʋudediwo
• Lãwo ƒe dander
• Nuɖuɖu aɖewo (e.g. notsi, azi , atikutsetse , ƒumelãwo ) .
• Nudzodzoewo ƒe ƒoƒo
• Atike aɖewo

2. Nuveviwɔame alo Dɔlékuiwo Xɔxɔ: Ne ŋutilãa xɔ abi, ŋutigbalẽa gbã, alo dɔlékui aɖe ge ɖe eme la, histamine dona. Histamine kpena ɖe ame ŋu be ʋu sina yia afisi abi la le la dzina ɖe edzi, eye wòhea nusiwo hiã kple lãmenugbagbevi siwo wɔa avu kple dɔlékuiwo vɛ be woakpe ɖe abi la ŋu wòada.

Nukae histamine wɔna ɖe ŋutilãa ŋu?

Ne histamine do le ŋutilãa me la, ezɔna yia míaƒe ŋutilã ƒe akpa vovovowo eye wòwɔa dɔ vovovowo.

• Ʋukawo : Histamine nana ʋuka suesuesue siwo le míaƒe ŋutilã me kekena. Woyɔa esia be ʋukawo kekeɖenudɔ . Esia wɔnɛ be ʋu geɖe sina toa wo me. Esia tae ɣeaɖewoɣi ne nulɔdɔ aɖe le ŋuwò la, wò ŋutigbalẽ biãna eye nèsena le ɖokuiwò me be dzoxɔxɔ. Azɔ hã, tsiwo dzea dodo gɔme tso ʋukawo ƒe gliwo me. Esia nana wòvuvuna (Swelling/ Edema ), ŋɔti me tsi sisina , eye tsi nɔa ŋkuwo ŋu.
• Yagbɔgbɔ ƒe ɖoɖo : Histamine nana lãmeka siwo le lãkusiwo me la xena. Woyɔa esia be aɖuɖɔtoe me ʋuʋu . Esia nana gbɔgbɔ sesẽna eye wòsena le eɖokui me be akɔta tena, vevietɔ le amesiwo ŋu asrã le gome .
• Ŋutilã: Histamine ate ŋu aʋã lãmeka siwo ƒe nuwuwu le ŋutigbalẽa me eye wòana ʋuʋudedi/ʋuʋudedi. Ewɔa nusi hã nana be ʋuʋudedi dzĩ siwo vuvu (hives/urticaria) dzena le ŋutigbalẽa ŋu.
• Nuɖuɖumeŋusẽ: Lãmetsi siwo le dɔgboa me ƒe tete ate ŋu ana dɔgbo natsi, aɖuɖɔtoe, aɖuɖɔtoe, kple aɖuɖɔtoe. Histamine kpena ɖe ame ŋu hã be dɔgbo me acid dona.
• Lãmetsiŋusẽ: Histamine hã wɔa dɔ abe ahɔhɔ̃mekawo ƒe dɔwɔwɔ ene le ahɔhɔ̃a me. Esia fia be ekpena ɖe ame ŋu wòtsɔa gbedasiwo yia lãmekawo ƒe lãmenugbagbeviwo dome. Esia kpena ɖe mía ŋu vevietɔ le míaƒe ŋudzɔnɔnɔ kple ŋudzɔnɔnɔ me. (Esia tae nulɔdɔtike xoxo aɖewo nana míedɔa alɔ̃, elabena woɖea histamine ƒe dɔwɔwɔ le ahɔhɔ̃a me hã dzi kpɔtɔna.)

Nukae nye histamine ƒe dzidziɖedzi ƒe dzesiwo?

Histamine ƒe agbɔsɔsɔ fũ ƒe dzesiwo ate ŋu ato vovo tso ame ɖeka gbɔ yi bubu gbɔ, le alesi gbegbe histamine do kple ŋutinu si ŋu wògblẽ nu le wu nu.

• Ŋutilã ƒe dzesiwo:
• Ŋutilã ƒe biã, ʋuʋudedi
• Eczema, ʋuʋudedi, ʋuʋudedi
• Urticaria/Hives: Ŋutilã ƒe akpa siwo kpata, siwo biã, siwo vuvu, eye wole ʋuʋum vevie.
• No kple ŋɔti ƒe dzesiwo:
• Aɖuɖɔɖɔɖɔ
• Rhinorrhea alo no me ʋuʋu
• No, ŋɔti, kple aɖu si le ʋuʋum
• Kpe
• Kɔ ƒe vuvu, gbe ƒe tɔtrɔ
• Dzesi siwo do ƒome kple ŋku:
• Ŋku dzĩ siwo le ʋuʋum
• Aɖatsiwo nɔ sisim tso ŋkuwo dzi
• Ŋku ƒe ʋuʋudedi
• Dzesi siwo do ƒome kple aklã:
• Yagbɔgbɔ sesẽ, gbɔgbɔtsixetsixe
• Seselelãme be akɔta le tetem
• Wheezing (whistling) ne wole gbɔgbɔm
• Ne asrã le ŋuwò la, asrã ƒe sesẽ
• Dzesi siwo do ƒome kple nuɖuɖumeŋusẽ:
• Aɖuɖɔtoe, ʋuʋudedi
• Dɔgbo ƒe vevesese, ʋuʋudedi
• Dɔmetɔtrɔ
• Nu bubu siwo le eme:
• Taɖuame (taɖuame) .
• Taɖuame
• Ʋu ƒe sisi (vevietɔ le dɔléle sesẽwo me) .

Tsɔe be xɔ̃wò Sugath ɖu lãgbalẽ aɖewo. Le gaƒoƒo afã me la, eƒe ŋutilã bliboa nɔ ƒoƒom eye ʋuʋudedi dzĩ aɖe nɔ eŋu. Gbɔgbɔ nɔ sesẽm nɛ. Esia ate ŋu atso esi Sugath ƒe ŋutilã ɖe histamine gbogbo aɖe ɖe go zi ɖeka le shrimp la ta.

Nɔnɔme si me afɔku le wu: Anaphylaxis

Esiae nye histamine ƒe dɔléle si nu sẽ wu eye wòdea ame ƒe agbe afɔku me . Woyɔa esia be anaphylaxis . Le esia me la, histamine gbogbo aɖe dona le ŋutilã bliboa me zi ɖeka. Esia ate ŋu adzɔ le aɖabaƒoƒo ʋɛ aɖewo ko me. Dzesi vevi siwo dzena le anaphylaxis ŋue nye:

• Yagbɔgbɔ sesẽ vevie (yaƒoƒomɔ̃a ƒe ʋuʋu le ŋɔti kple aɖe ƒe vuvu ta) .
• Taɖuame, sese le ame ɖokui me be yegbɔdzɔ
• Dzi ƒe tsotso
• Ʋu ƒe sisi ƒe ɖiɖi kpata
• Tɔtɔ
• Ŋutilã si le blɔ alo ɣie

Ne èkpɔ dzesi siawo dometɔ aɖe la, ke atikewɔwɔ kpatae wònye. Ele be woakplɔ wò ayi kɔdzi enumake. Atikewɔwɔ hehe ɖe megbe ate ŋu ade ame ƒe agbe afɔku me. Atikewɔwɔ gbãtɔ le nɔnɔme mawo me enye adrenaline (Adrenaline/Epinephrine) dodo.

Aleke woawɔ aɖu histamine ƒe ŋusẽkpɔɖeamedzi dzi?

Dzɔgbenyuietɔe la, mɔ siwo dzi míato aɖu vevesese siawo siwo histamine hena vɛ dzi la le mía si. 1. Antihistamines: Esiae nye atike ƒomevi vevitɔ. Atike siawo xea mɔ na teƒe siwo histamine blana ɖo (siwo woyɔna be histamine xɔlawo) . Esia xea mɔ na histamine be wòagakpɔ ŋusẽ ɖe edzi o.

• Dzidzime gbãtɔ ƒe atike siwo wua alɔ̃dɔdɔ: Esiawo ate ŋu ana ame nadɔ alɔ̃ vie (e.g., chlorpheniramine, diphenhydramine). Eyata ele be woaɖɔ ŋu ɖo ne wole wo nom le zã me alo ne wole dɔwo abe ʋukuku ene wɔm.
• Dzidzime evelia ƒe atike siwo wua ʋumenugbagbeviɣidɔ: Esiawo medɔa alɔ̃ fũ o (e.g., Loratadine, Cetirizine, Fexofenadine). Wozãa wo nyuie wu le ŋkeke me.

Ðɔkta atso nya me le atike si wua ʋumenugbagbeviɣidɔ si sɔ na wò kple ɣeyiɣi didi si wòle be nànoe ŋu. 2. Nusiwo naa lãmenugbagbeviwo nɔa te sesĩe:Atike siawo wɔa dɔ to mɔxexe ɖe histamine ƒe dodo tso mast cells me nu. (Kpɔɖeŋu: Cromolyn sodium). Esiawo va abe atike siwo wotsɔna ƒua gbe ɖe ŋɔti me kple ŋkumeɖonu ene. 3. Corticosteroids: Esiawo nye atike sẽŋu siwo ɖea dɔdzẽ dzi kpɔtɔna. Ɣeaɖewoɣi la, wozãa wo ɣeyiɣi kpui aɖe tsɔ léa asrã nu le nulɔdɔ sesẽwo me. 4. Ƒo asa na nusiwo hea dɔlélea vɛ: Ne ènya nusiwo ŋu wò nulɔdɔ le la, anyo wu be nàƒo asa na nu mawo alesi nàte ŋui. Le kpɔɖeŋu me, ne ke melɔ̃a wò o la, àte ŋu awɔ nuwo abe wò aƒea me dzadzraɖo kple ametakpɔnu ne èdo go le gota le aŋɔkaɣi ene.

Nukae Nye Histamine ƒe Mɔmaɖemaɖeɖenuŋu?

Esia to vovo vie tso nulɔdɔwo gbɔ. Histamine ƒe mɔmaɖemaɖeɖenuŋu nye ne míaƒe ŋutilã mete ŋu mãa histamine nyuie tso nuɖuɖu me alo tso histamine agbɔsɔsɔme si dona le ŋutilãa me me o. Nusi koŋ gbɔ esia tsoe nye dɔlékui si nye Diamine Oxidase (DAO) ƒe ɖiɖi . Le go sia me la, dzesi siwo le nulɔdɔ me (ʋuʋudedi, taɖuame, dɔgbo ƒe kuxiwo) ate ŋu ado mo ɖa. Gake esia dzɔna ne wole nuɖuɖu siwo me histamine sɔ gbɔ ɖo ɖum (e.g., cheese si tsi, nuɖuɖu siwo wotsɔ ƒo ƒu, wein, amagbe aɖewo kple atikutsetsewo). Ne ɖikeke aɖe le mewò le esia ŋu la, anyo wu be nàyi ɖɔkta gbɔ aƒo nu kpli wo.

Ɣekaɣie wòle be nàkpɔ ɖɔkta?

Zi geɖe la, menyo be nàƒle atike si wua ʋumenugbagbeviɣidɔ le atikedzraƒe na nulɔdɔ ƒe dzesi suesuesuewo o. Gake le nɔnɔme siawo tɔgbe me la, ele be nàkpɔ ɖɔkta godoo:

• Ne èkpɔa nulɔdɔ ƒe dzesi sesẽwo enuenu.
• Ne wometsɔ atike siwo wozãna edziedzi ɖu dzesiawo dzi o.
• Ne èse le ɖokuiwò me be gbɔgbɔ sesẽ na ye alo akɔta le tetem.
• Ne èkpɔ anaphylaxis ƒe dzesi aɖe (esia nye nudzɔdzɔ kpata!).
• Ne èdi be yeanya nusi tututu ŋu wò nulɔdɔ le ( nulɔdɔ dodokpɔwo li na ema).
• Ne ɖikeke aɖe li be histamine ƒe dɔmawɔmawɔ nyuie.

Ðɔkta ate ŋu ada wò nɔnɔmea kpɔ nyuie eye wòana atike nyuitɔ kekeake kple aɖaŋuɖoɖo nyuitɔ kekeake si nèhiã la wò.

Mlɔeba la, nusiwo dzi wòle be woaɖo ŋkui (Take-Home Message) .

Eyata togbɔ be histamine nye atike vevi aɖe na míaƒe ŋutilã hã la, ate ŋu aɖe fu vie ɣeaɖewoɣi.

• Histamine wɔa akpa vevi aɖe le nulɔdɔwo me, eye wòkpena ɖe abi ƒe dɔyɔyɔ kple dɔgbo ƒe dɔwɔwɔ hã ŋu.
• Nuwo abe aɖuɖɔtoe, ŋutigbalẽ ƒe ʋuʋu, aɖuɖɔtoe, kple ŋɔti ƒe ʋuʋu ate ŋu atso histamine gbɔ.
• Anaphylaxis ye nye nɔnɔme si me afɔku le wu si histamine hena vɛ. Enye atikewɔwɔ kpata si hiã be woawɔ atike na ame kpata.
• Atike siwo wua histamine ye nye atike vevitɔ siwo kpɔa histamine ƒe ŋusẽkpɔɖeamedzi dzi.
• Ne nulɔdɔ ƒe dzesiwo dzena le ŋuwò enuenu alo wòsẽna la, kpɔ egbɔ be yedi atikewɔlawo ƒe aɖaŋuɖoɖo.

Naneke meli si ŋu woatsi dzi ɖo o. Woate ŋu akpɔ nɔnɔme siawo siwo do ƒome kple histamine ƒe akpa gãtɔ gbɔ dzidzedzetɔe. Nu vevitɔe nye be nàlé ŋku ɖe wò ŋutilã ŋu eye nàdi atikewɔlawo ƒe aɖaŋuɖoɖo nyuitɔ ne ehiã. histamine, nulɔdɔ, nulɔdɔ, nulɔdɔ, antihistamine, anaphylaxis, urticaria, asrã, அல்ஜி, அல்ஜி