Èbu alesi vidzidɔ, vidzidɔ, kple vidzidɔ, ŋutinu siwo le etɔxɛ na nyɔnuwo, tsina le vidzĩ ƒe agbenɔɣi ƒe gɔmedzedze ŋutɔ ŋu kpɔa? Enye nuwɔna wɔnuku aɖe si gɔme sese sesẽ vavã. Nusianu dzea egɔme tso mɔ̃ sue eve siwo le tsɛ ŋutɔ siwo dzɔna le fugboe ƒe ɣeyiɣia me dzi. Le atikewɔwɔ me la, míeyɔa esiawo be ‘Müllerian ducts’. Ðewohĩ mèse ŋkɔ sia kpɔ o. Gake ne míeƒo nu tso nyɔnu ƒe vidzidzi ƒe lãmesẽ ŋu la, ele vevie be nànya nu tso mɔ̃memi ƒe ɖoɖo sia ŋu. Eyata egbea, mina míaƒo nu tso eŋu bɔbɔe eye le mɔ si gɔme nàte ŋu ase nu.
Kpuie ko la, nukawoe nye Müllerian Duct siawo?
Müllerian ducts nye mɔ̃ eve eve siwo dzɔna le fugboe me ne ele tsitsim le vidadaa ƒe vidzidɔ me. Wogayɔa mɔ̃ siawo be paramesonephric ducts. Gake ŋkɔ Müllerian ducts ye wozãna wu.
Woƒe dɔ vevitɔe nye be woawɔ nyɔnu ƒe vidzidzi ƒe ŋutinu veviwo. Etɔxɛe la, mɔ̃ eve siawoe va zua ŋutinu siawo emegbe:
- Vidzidɔ: Ŋutinu wɔnuku si tsɔa vidzĩ eye wònaa nunyiame ɣleti enyi.
- Fallopian tubes: Tsi eve siwo tsɔa azi tso azigolo me yia vidzidɔa me.
- Vidzidɔ: Vidzidɔa ƒe akpa si le anyime si do ƒome kple nyɔnu ƒe vidzidɔ.
- Vidzidɔa ƒe akpa si le etame.
Bu eŋu kpɔ ko, mɔ̃ sue eve siawoe tsina zua ŋutinu vevi siwo hiã be woazu vidada ahadzi vi le etsɔme.
Nusi wɔ nuku enye be Müllerian ƒe mɔ̃ siawo nɔa fugboewo katã me, eɖanye ŋutsu alo nyɔnu ka kee woɖanye o, le woƒe tsitsi ƒe gɔmedzedze. Eyata aleke wòdzɔe be vidzĩ si nye ŋutsu metu vidzidɔ o, ke boŋ vidzĩ nyɔnu koe?
Nusitae nye gbɔdɔdɔ ƒe vovototodedeameme, si nye nusi dzi gbɔdɔdɔ ƒe ŋutinuwo tona tsina. Le ŋutsu ƒe fugboe me la, lãmetsi tɔxɛ aɖe si woyɔna be anti-Müllerian hormone (AMH) dona. Lãmetsi sia xea mɔ na Müllerian ƒe ʋukawo ƒe tsitsi eye wògblẽa wo vivivi. Esia wɔe be fugboe si nye ŋutsu metu ŋutinuwo abe vidzidɔ ene o.
Gake le nyɔnu fugboe me la, AMH lãmetsi sia menɔa eme o. Eyata Müller ƒe ʋukawo tsina mɔxenu aɖeke manɔmee, eye nyɔnuwo ƒe vidzidzi ŋutinu siwo míeyɔ va yi la dzɔna.
Eyata nukae nye Wolffian Ducts? Vovototo kae le wo ame evea dome?
Tsɔ kpe ɖe Müllerian ducts ŋu la, ducts ƒe ɖoɖo bubu si le fugboe gbãtɔ ɖesiaɖe me enye Wolffian ducts. Wogayɔa esiawo be mesonephric ducts. Dɔwɔna eve siawo ƒe dɔwɔwɔ to vovo kura tso wo nɔewo gbɔ. Be nàse esia gɔme nyuie la, kpɔ kplɔ̃ si le ete.
| Ŋutinu | Müller ƒe Tɔdzisasrãwo | Wolffian ƒe Tɔdzisasrãwo |
|---|---|---|
| Dɔ vevitɔ | Tsitsi va zu nyɔnu ƒe vidzidzi ƒe ŋutinuwo. | Tsitsi va zu ŋutsu ƒe vidzidzi ƒe ŋutinuwo. |
| Le nyɔnu fugboe me | Etsina nyuie eye wòwɔa vidzidɔ, vidzidɔ, kple bubuawo. | Vivivi la, egblẽna, eye wògblẽa kakɛ siwo meɖi naneke o ɖi. |
| Le fugboe si nye ŋutsu me | Lãmetsiŋusẽ si tsia tre ɖe Müllerian ŋu (AMH) nana tsitsi nu tsona eye wòƒuna. | Etsina nyuie le lãmetsi si nye testosterone ƒe ŋusẽkpɔɖeamedzi te. |
| Lãmenugbagbevi siwo tsina hewɔa wo | Vidzidɔ, vidzidɔ, vidzidɔ, vidzidɔ ƒe akpa si le etame. | Vas deferens, epididymis, tsinyenye ƒe ʋukawo. |
Kpuie ko la, togbɔ be ʋuka siawo evea siaa le fugboe ɖeka me hã la, le lãmetsiŋusẽ ƒe ŋusẽkpɔɖeamedzi te la, ɖeka tsina esime evelia tsina. Esiae nye dzɔdzɔme ƒe dadasɔ wɔnuku.
Aleke mɔ̃ siawo tsina eye afikae wole?
Nuwɔna sia dzea egɔme le fufɔfɔ ƒe gɔmedzedze ŋutɔ. Wofɔa vi le vidzidɔ me le kwasiɖa 3-4 le edzidzi megbe.Ŋutinya sia dze egɔme le fufɔɣi lɔƒo. Ɣemaɣi la, Müllerian-mɔ̃ siawo dzea tsitsi gɔme le ayiku gbãtɔ (mesonephric ayiku) siwo le fugboea me la gbɔ. Ayiku gbãtɔ siawo nyea ɣeyiɣi kpui aɖe ƒe ayiku, eye ayiku siwo nɔa anyi ɖaa va dona emegbe.
Tsimɔ siawo tsina yia anyime abe asibidɛ didi siwo do ɖe ŋgɔ ene. Le fufɔfɔ ƒe kwasiɖa 8 va ɖo 12 dome la, Müllerian-mɔ̃ eve siwo ɖiɖina ƒe nugbɔwo ƒoa ƒu ɖekae. Fusion siae nyea gɔmeɖoanyi na ŋutinuwo abe vidzidɔ kple vidzidɔ ene. Lãmenugbagbevi ƒomevi tɔxɛ evee le mɔ̃ siawo me.
- Lãmenugbagbevi siwo le lãkusi me: Esiawo le abe nutsyɔnu si kpɔa míaƒe ŋutinuwo ta ene eye wokpena ɖe ame ŋu hã be woaxɔ nu veviwo ahaɖe wo ɖa.
- Mesenchymal cells: Esiawo nye lãmenugbagbevi ƒomevi aɖe. Esia fia be lãmenugbagbevi siawo ate ŋu atrɔ ava zu lãmenugbagbevi ƒomevi vovovowo ne ehiã.
Ðe Müllerian duct anomalies ate ŋu adzɔa?
Ẽ, ɣeaɖewoɣi la, Müller ƒe mɔ̃ siawo metsina nyuie o alo womedoa ka kple wo nɔewo o, si wɔnɛ be nu gblẽ le wo ŋu kple nusiwo mesɔ o vovovowo dona. Zi geɖe la, nɔnɔme siawo nyea nɔnɔme siwo wodzina .
Nu vevitɔe nye be ɖewohĩ mànya be nɔnɔme sia le ye ŋu o vaseɖe esime nèɖo tsitsime alo nèɖe srɔ̃ eye nèle mɔ kpɔm na vi. Elabena ɖewohĩ gotagome dzesi aɖeke manɔ anyi o. Ne wole nusiwo gbɔ vidzidzi tsona dim ko hafi nyɔnu aɖewo va kpɔnɛ be nɔnɔme sia le yewo ŋu.
Tabla si le ete la yɔ Müllerian duct ƒe gbagbã siwo bɔ wu dometɔ aɖewo.
| Ŋkɔ na nusi mesɔ o | Nukae le dzɔdzɔm ko? |
|---|---|
| Müller ƒe agenesis alo hypoplasia | Vidzidɔa menɔa vidzidzi me o (agenesis) alo le sue ŋutɔ eye metsi o (hypoplasia) . Esia ƒe kpɔɖeŋu si bɔ wue nye domenyiŋusẽfianu ƒe nɔnɔme si nye Mayer-Rokitansky-Kuster-Hauser (MRKH) ƒe dɔléle . |
| Vidzidɔ ƒe ʋuka | Ne mɔ̃ eveawo meva kpe ɖe wo nɔewo ŋu nyuie ne wowɔ ɖeka le ete o la, lãkusi aɖe dzɔna le nyɔnu ƒe vidzidɔa me. Esia ate ŋu ana be vidzidɔa ƒe akpa aɖe naxe alo keŋkeŋ, alo woate ŋu awɔ nyɔnu ƒe vidzidɔ eve. |
| Müllerian duct syndrome si nɔa anyi ɖaa (PMDS) . | Esia nye domenyiŋusẽfianu ƒe nɔnɔme si mebɔ o si dzea ŋutsuviwo dzi. Esi AMH lãmetsiŋusẽa mewɔa dɔ nyuie o ta la, vidzidɔ kple vidzidɔ ƒe ʋukawo va dona kpe ɖe ŋutsu ƒe vidzidziŋutete siwo sɔ ŋu. Kuxiwo abe vidzidɔ siwo meɖiɖi o ene hã ate ŋu anɔ ŋutsu siawo ŋu. |
| Vidzidɔ ƒe dɔmawɔmawɔ nyuie | Kuxi siwo le vidzidɔa ƒe tsitsi ŋu ate ŋu ana vidzidɔa ƒe nɔnɔme natrɔ. Kpɔɖeŋu aɖewoe nye vidzidɔ si me lãkusi eve le, vidzidɔ si nye didelphys, vidzidɔ si me septate le, kple vidzidɔ si ƒe nɔnɔme le abe T ene. |
Ame aɖewo siwo ŋu nɔnɔme madeamedzi siawo le hã ate ŋu akpɔ kuxiwo le woƒe ayiku ŋu. Esia le alea elabena ŋutinu eve siawo tsina ɖe wo nɔewo ŋu ŋutɔ le fugboea ƒe ɣeyiɣia me, eye nusi gblẽ le ɖeka ŋu ate ŋu agblẽ nu le evelia ŋu.
Ðe vodada siawo ƒomevi bɔa?
Ao, mehiã be nàtsi dzi ɖe esia ŋu o. Esiawo nye nɔnɔme siwo mebɔ kura o. Akɔntabubuwo ɖee fia be nɔnɔme madeamedzi sia ƒomevi dzɔna le vidzidzi agbagbee ƒe alafa memamã sue aɖe ŋutɔ me, si nye 0.1% va ɖo 3.0% . Esia fia be mɔnukpɔkpɔ si li be nane si le abe esia ene nadzɔ la le sue ŋutɔ.
Nya kawoe wòle be nàbia ɖɔktaa?
Ne ɖɔkta aɖe kpɔe be Müllerian duct defect le ŋuwò alo viwòa ŋu la, esɔ be nyabiase geɖe nanɔ susu me na wò. Ɣemaɣi la, mègahe naneke ɖe megbe o, bia nya siawo wò ɖɔkta.
- Ðe nɔnɔme sia akpɔ ŋusẽ ɖe nye vidzidzi (ŋutete be madzi vi) dzia?
- Ðe esia akpɔ ŋusẽ ɖe nye lãmetsiŋusẽ dzia?
- Nukawoe nye atike siwo wozãna na esia? Ðe wòhiã be woawɔ dɔ na amea?
- Ðe nye sɔhɛmenɔɣi kple dzinukpɔkpɔ adzɔ le mɔ si sɔ nua?
Wò ɖɔkta aɖo biabia siawo katã ŋu eme nakɔ eye wòana mɔfiame siwo nèhiã la wò.
Ðe woate ŋu axe mɔ ɖe vodada siawo ƒomevi nu le fufɔɣia?
Esia nye kuxi si le ame geɖe ŋu. Ne míagblɔe tututu la, mɔ aɖeke meli si dzi woato axe mɔ ɖe Müller ƒe duct ƒe gbagbãwo nu keŋkeŋ o.Elabena zi geɖe la, domenyiŋusẽfianu alo vodada aɖe si dzɔna le vome le fugboea ƒe tsitsime gbɔe esiawo tsona.
Gake, ema mefia be naneke meli míate ŋu awɔ o. Abe vidada si le mɔ kpɔm na fu ene la, àte ŋu azɔ ɖe agbe nyui nɔnɔ dzi be wòaɖe vidzidzi ƒe gbɔdzɔgbɔdzɔ ƒe afɔkua dzi akpɔtɔ le goawo katã me. Menye nɔnɔme madeamedzi siawo ƒomevi koe esia le vevie o, ke boŋ na viwòa ƒe lãmesẽ bliboa hã.
- Ƒo asa na atike vɔ̃ɖi siwo ŋu se meɖe mɔ ɖo o kple marijuana kura.
- Ƒo asa na atamanono kple aha sesẽ nono keŋkeŋ. Esiawo gblẽa nu le fugboea ŋu ŋutɔ.
- Kpɔ egbɔ be yexɔ atikewɔlawo ƒe aɖaŋuɖoɖo nyuiwo kple beléle na ye do ŋgɔ na vidzidzi le fufɔɣi.
- Ne dɔléle siwo nɔa anyi didi abe suklidɔ alo ʋusɔgbɔdɔ ene le ŋuwò la, ɖu wo dzi nyuie hafi nàfɔ fu.
- No vitamin siwo me folic acid le do ŋgɔ na vidzidzi abe alesi wò ɖɔkta kafui ene pɛpɛpɛ.
- Lé lolo si sɔ me ɖe asi.
- Ðu nuɖuɖu si da sɔ eye nàde kame vie gbesiagbe.
Àte ŋu azã nu bɔbɔe siawo atsɔ awɔ nɔnɔme nyuitɔ kekeake na viwò si le dɔme na wò be wòatsi le lãmesẽ me.
Gbedasi si Wotsɔ Yi Aƒeme
- Müllerian ducts nye ducts ƒe ɖoɖo aɖe si dzɔna le fugboe ƒe nɔnɔme me eye wònye nu vevi aɖe le nyɔnu ƒe vidzidziŋutetewo abe vidzidɔ kple vidzidɔ ƒe ʋukawo ene ƒe tsitsi me.
- Tsitsi ƒe gbɔdzɔgbɔdzɔ siawo nɔa vidzidzi me eye ɖewohĩ womade dzesii o vaseɖe esime wova tsi alo ne wole mɔ kpɔm na vi.
- Gbɔdzɔgbɔdzɔ siawo mebɔ kura o, eye wo dometɔ akpa gãtɔ ƒe atikewɔwɔ kple wo gbɔ kpɔkpɔ ƒe mɔnuwo le wo si.
- Ne dzitsitsi alo ɖikeke aɖe le mewò ku ɖe esia ŋu la, ele vevie ŋutɔ be nàƒo nu tso eŋu kple wò ɖɔkta gaglãa eye nàxɔ aɖaŋuɖoɖo nyuitɔ.
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