Ðe ayikudɔnɔwo nya esia ne wowɔ MRI na yewoa? Mina míaƒo nu tso Nephrogenic Systemic Fibrosis (NSF) ŋu!

Ðe ayiku me kuxi aɖewo le ŋuwòa? Alo ɖe ɖɔkta aɖe gblɔ na wò be wò ayikuwo mele dɔ wɔm nyuie oa? Ɣeaɖewoɣi ne ele be woawɔ scan na wò abe Magnetic Resonance Imaging (MRI) ene la, ele be nàɖɔ ŋu ɖo vie le amadede tɔxɛ si nèzã ŋu. Egbea la, míele nu ƒom tso nɔnɔme aɖe si ate ŋu adzɔ le ɣeyiɣi mawo tɔgbe me, gake mebɔ kura fifia o, gake enyo be míanya nu tso eŋu. Woyɔa esia be Nephrogenic Systemic Fibrosis (NSF) ƒe dɔléle.

Nukae nye NSF (Nephrogenic Systemic Fibrosis) sia? Kpuie ko la,...

Kpuie ko la, Nephrogenic Systemic Fibrosis (NSF) nye dɔléle si mebɔ kura o. Ame siwo ŋu ayikudɔ le koŋue wòdzɔna le, vevietɔ amesiwo ƒe ayiku megawɔa dɔ nyuie o. Ne wona gadolinium-based contrast agents (GBCA) ame aɖe le fotoɖeɖe me, abe MRI ene, be nɔnɔmetataawo me nakɔ nyuie ko hafi nɔnɔme sia ate ŋu adzɔ.

Bu eŋu kpɔ, míaƒe ayikuwoe ɖea nusiwo míedi o le míaƒe ŋutilã me ɖa eye wotsɔa aɖuɖɔ ɖea wo doa goe. Eyata, ne nusi woyɔna be ``GBCA'' siawo ge ɖe ame aɖe si ƒe ayikuwo mele dɔ wɔm nyuie o ƒe ŋutilã me la, womeɖea wo ɖa le ŋutilãa me nyuie o. Ɣemaɣie NSF ƒe afɔkua doa mo ɖa.

Ènya nusi hea NSF vɛa? Wò ŋutigbalẽ ate ŋu aƒo, abla, avuvu, eye wòavuvu. Ɣeaɖewoɣi la, ƒunukpeƒewo gɔ̃ hã te ŋu sesẽna eye wotua wo ɖe teƒe ɖeka. Woyɔa esia be ``ƒunukpeƒe ƒe ʋuʋu''. Menye ema ɖeɖeko o, ke le ame aɖewo gome la, nɔnɔme sia ate ŋu agblẽ nu le ŋutinu siwo le ŋutilãa me, abe akɔta ƒe lãmekawo, dzitodzitowo, kple lãkusiwo ene hã ŋu. Nusi dzɔnae nye be lãmeka siwo ƒo xlã ŋutinu mawo hã ƒoa ke ɖe to eye wosẽna.

Nu vevitɔe nye be, ne NSF nya dzɔ ko la, fifia la, atikewɔwɔ si me kɔ aɖeke meli si dzi woato atɔ te alo atrɔe o.

Gake, mègatsi dzi o! United States ƒe Nuɖuɖu Kple Atike Ŋuti Dɔwɔƒe (FDA) gɔ̃ hã ɖo aɖaŋu vevie be woagazã GBCA xoxo aɖewo le ayikudɔlélawo ŋu o. Womeka nya ta be GBCA yeye siwo le asi me la hea NSF vɛ le ayikudɔnɔwo me o. Ema nye gbɔdzɔe gã aɖe.

Aleke gbegbee NSF bɔ fifiae?

Le nyateƒe me la, ƒã ŋutɔ, ƒã ŋutɔ fifia. Le nyateƒe me la, womekpɔ NSF dɔlékui yeye aɖeke le ƒe 10 kple edzivɔ me o. Le ƒe 2006 megbe la, esi atikewɔlawo va nya kadodo si le ``(GBCAs)`` siawo kple ayikudɔ dome la, dɔléle sia ŋuti nyatakakawo ƒe xexlẽme dzi ɖe kpɔtɔ ŋutɔ.

Aleke NSF dzɔnae? Nukawoe nye dzesiawo?

NSF ƒe dzesiwo ate ŋu adze le gbesigbe wodo atike siwo me gadolinium le (GBCAs) ɖe ŋutilãa me. Alo, woate ŋu ado le ɣleti aɖewo megbe. Le numekuku aɖe me la, ame siwo ade 50% ƒe dzesiwo dze le ŋkeke 12 me.

Dzesi vevi siwo woate ŋu akpɔe nye:

• Ŋutilã ƒe vuvu, eƒe tete, kple eƒe ƒoƒoe: Esia gblẽa nu le teƒewo abe abɔwo, afɔwo, kple akɔta kpakple ƒodo ene ŋu wu. Ƒã hafi wògblẽa nu le mo ŋu.
• Teƒe doviviti alo ƒoƒo ɖe ŋutigbalẽa ŋu: Ɣeaɖewoɣi la, ŋutigbalẽa ate ŋu azu ƒuƒlu, abe amititsetse ƒe aŋgba ene.
• Ŋutilã ƒe ʋuʋu, abi, alo vevesese.
• Mate ŋu aʋuʋu abɔ kple ƒunukpeƒewo le mɔ si sɔ nu le ŋutigbalẽa ƒe ƒoƒo kple vuvu ta.

Le ame aɖewo gome la, dzesi siawo ate ŋu agblẽ nu le ŋutilãa ƒe ŋutinuwo kple lãmekawo hã ŋu. Nu siwo nàte ŋu ato la dometɔ aɖewoe nye esi:

• Lãmetsiwo ƒe gbɔdzɔgbɔdzɔ sesẽ.
• Le lãmekawo ƒe tete ta la, abɔwo mate ŋu abɔbɔ alo akeke wo ɖe enu nyuie o (i.e., ʋuʋu ƒe didime dzi ɖena kpɔtɔna).

Ne fibrosis sia, alo lãmekawo ƒe ƒoƒo ɖe edzi yi ŋgɔe la, ate ŋu ana nu sesẽwo naƒo ƒu ɖe lãmekawo, lãkusiwo, nuɖuɖutome, ŋkuwo, kple dzi gɔ̃ hã me. Esia ate ŋu agblẽ nu le ŋutinu siawo ƒe dɔwɔwɔ ŋu. Esia ate ŋu ana ame nazu nuwɔametɔ ɣeyiɣi didi, si anɔ anyi ɖaa, eye le go aɖewo me la, aku gɔ̃ hã.

Nuka koŋ gbɔe NSF tsona?

NSF anya tso `(gadolinium-based contrast agents - GBCAs)` si míeyɔ va yi gbɔ. Wozãa atike sia si woyɔna be gadolinium tsɔ naa nɔnɔmetatawo me kɔna le `(MRI)` ƒe fotoɖeɖewo me. Womenya alesi tututu gadolinium hea NSF vɛ haɖe o. Ke hã, eme kɔ ƒã be kadodo aɖe le ayikudɔ kple `(GBCAs)` dome. Woɖee fia hã be afɔkua dzina ɖe edzi ne gadolinium si wodona na ŋutilãa sɔ gbɔ, alo ne wozã `(GBCAs)` ƒomevi aɖewo.

NSF bɔ ɖe amesiwo ŋu ayikudɔléle si nɔa anyi didi (CKD) le kple amesiwo le ʋumenugbagbeviɣidɔ wɔm le ayiku ƒe dɔmawɔmawɔ nyuie ta me wu.

Gake, ɖo ŋku edzi be womekpɔ NSF dɔlékui yeye aɖeke le ƒe 15 kloe me o!

Esia le alea elabena GBCA siwo li fifia la li ke wu eye aɖi mele wo me o. Azɔ hã, amesiwo ŋu ayikudɔ le koe wozãa gadolinium. FDA gɔ̃ hã kafui be amesiwo ŋu ayikudɔ alo ayiku me kuxiwo le la nagazã GBCA xoxoawo o.

Amekae ate ŋu atu esia ɖo wu? (Afɔku Siwo Le Ame Ŋu) .

Afɔku vevitɔ si ate ŋu ana NSF nadze ame dzi enye ayikudɔ alo ayiku ƒe dɔmawɔmawɔ nyuie. Esia lɔ ayiku ƒe dɔwɔwɔ na ame va yi, ayiku dodo na ame, alo ayiku ɖeka ko wɔwɔ ɖe eme. Azɔ hã, ne nɔnɔme bubuwo le amesi ŋu ayikudɔ le ŋu, abe ʋu ƒe sisi ƒe kuxiwo alo dɔlékuiwo ene la, NSF ƒe afɔkua ate ŋu asɔ gbɔ vie.

Gake fifia ɖɔktawo nya nu tso nusiwo GBCA xoxowo ate ŋu agblẽ le amesiwo ƒe ayiku ƒe dɔwɔwɔ dzi ɖe kpɔtɔ ŋu nyuie wu. Eyata esi mɔnu siwo le dedie wu li egbea ta la, afɔku si le wò be nàxɔ dɔléle sia la le ʋɛ wu kura.

Nukawoe nye kuxi siwo ate ŋu ado tso NSF me?

NSF ƒe kuxiwo ate ŋu anye nu sesẽ ŋutɔ eye ɣeaɖewoɣi woate ŋu awu ame. Dzesi gbãtɔe nye ŋutigbalẽa ƒe ƒoƒo alo eƒe ƒoƒo. Gake ne nɔnɔmea le sesẽm ɖe edzi la, sesẽ sia ate ŋu agblẽ nu le ŋutinuwo kple lãmeka siwo le ŋutilãa me hã ŋu. Le kpɔɖeŋu me, wò lãmekawo kple ƒunukpeƒewo ate ŋu asẽ ale gbegbe be màte ŋu aʋuʋu wo o, si ana màte ŋu azɔ o. Ne NSF gblẽ nu le lãkusi alo dzi ŋu la, ate ŋu ana gbɔgbɔ nasesẽ alo agblẽ nu le dzia ƒe ŋutete be wòakɔ ʋu ŋu.

Aleke wowɔna dea dzesi dɔléle sia pɛpɛpɛ? (Dɔléle ƒe dzesi) .

Mɔ ɖeka kolia si dzi nàto anya kple kakaɖedzi ne NSF le ŋuwòe nye be nàwɔ ŋutigbalẽ ƒe lãmenugbagbeviwo ƒe dodokpɔ. Esia bia be ɖɔkta naɖe wò ŋutigbalẽ sue aɖe atsɔ aɖoe ɖe dodokpɔxɔ me be woadae kpɔ. Gake ne, le wò atikewɔwɔ ŋutinya xɔxɔ kple ŋutilãmedodokpɔ vɔ megbe la, ɖikeke si sɔ be ɖewohĩ NSF le ŋuwò ko hafi ɖɔkta aɖe gbe be woadoe kpɔ.

Nukawoe nye atike siwo wozãna na NSF?

Le nyateƒe me la, fifia la, atikewɔmɔnu tɔxɛ aɖeke meli si dzi woda asi ɖo na NSF o. Esi dɔlélea mebɔ o ta la, numekuku siwo wowɔna le atikewɔmɔnuwo ŋu mesɔ gbɔ o. Gake atikewɔwɔ ʋɛ aɖewo li siwo ŋu woka nya ta le be wonaa gbɔdzɔe aɖe NSF dɔnɔ aɖewo:

• Ne wowɔ MRI vɔ la, ʋumenugbagbeviɣidɔ ate ŋu aɖe gadolinium la ɖa le ŋutilãa me. Esia ate ŋu akpe ɖe amesiwo ŋu ayikudɔléle si nɔa anyi didi le ŋu. Gake kpeɖodzi aɖeke meli be esia ana NSF ƒe ŋgɔyiyi natɔ te keŋkeŋ o.
• Lãmesẽfefewɔwɔ ate ŋu akpe ɖe ame ŋu be ƒunukpeƒewo nate ŋu atrɔ ɖe nɔnɔmewo ŋu ahanɔ ʋuʋum.
• Ayiku dodo nye tiatia si ŋu NSF dɔnɔ aɖewo ate ŋu abu.

Ne ayikudɔ le ŋuwò la, anyo wu be nàƒo asa na gadolinium zazã. Gake ɣeaɖewoɣi la, ate ŋu ahiã be woatsɔ gadolinium awɔ nɔnɔmetata nyuitɔwo kekeake tso MRI me. Le nɔnɔme mawo me la, ele be ɖɔktawo nada viɖe siwo le MRI ŋu akpɔ kple afɔku siwo le gadolinium zazã me. Ne ayiku me kuxiwo le ŋuwò eye wò ɖɔkta bia be woatsɔ amadede awɔ MRI la, kpɔ egbɔ be yebia wò ɖɔkta nenye be NSF le afɔku me.

Ðe mɔ aɖewo li siwo dzi woato aƒo asa na NSF? (Mɔxexe ɖe enu) .

Mɔ nyuitɔ si dzi woato axe mɔ ɖe NSF nu enye be woaƒo asa na GBCA xoxowo zazã le amesiwo ŋu ayikudɔ le ŋu. GBCA yeyewo le dedie wu eye aɖi mele wo me na ayiku dɔnɔwo o.

FDA kafui be amesiwo ŋu ayikudɔ aɖewo le la nagazã amadede siwo me gadolinium le o negbe ɖe mɔnu bubu aɖeke meli o hafi.

Le amesiwo ƒe ayikuwo wɔa dɔ nyuie gome la, edze abe afɔku aɖeke mele GBCA-tikewo zazã me o ene.

Nukae nye ame siwo kuna le NSF ta?

Do ŋgɔ na ƒe 2019 la, FDA ka nya ta be ame 3,094 ye xɔ NSF eye ame 742 ku le esia ta. Gake abe alesi míegblɔe va yi ene la, womekpɔ dɔléle yeye aɖeke le ƒe 10 kple edzivɔ me o. Susu vevitɔ si tae nye be FDA kple atikewɔlawo nya nu tso ŋusẽ si GBCA-wo kpɔna ɖe ayikudɔnɔwo dzi.

Ɣekaɣie wòle be míadi atikewɔlawo ƒe aɖaŋuɖoɖo?

Ne ayikudɔ le ŋuwò eye dzesi siwo gbɔna dometɔ aɖe dze ŋuwò la, yi ɖɔkta enumake elabena woate ŋu anye NSF ƒe dzesi:

• Ŋutilã ƒe tete alo eƒe ʋeʋẽ lilili.
• Ŋutilã si le vuvu alo abi.
• Teƒe dzĩ alo viviti siwo le ŋutigbalẽa ŋu.

Le dedienɔnɔ ŋuti ɖoɖo siwo li fifia nu la, mɔnukpɔkpɔ si li be woakpɔ NSF le ŋuwò la le sue ŋutɔ. Gake ne ayikudɔ le ŋuwò eye wòhiã be woawɔ MRI la, ƒo nu kple wò ɖɔkta tso NSF kple afɔku siwo le eme na wò ŋu. Togbɔ be aɖi mele GBCA yeyeawo me nenema o eye edze abe wole dedie ene hã la, anyo ɣesiaɣi be nàgblɔ wò lãmesẽ ŋutinya na wò ɖɔkta eye nàdzro afɔku siwo le eme me.

Gbedasi si Wotsɔ Yi Aƒeme

Enyo, eyata fifia èse NSF si ŋu míeƒo nu tsoe la gɔme nyuie wu. Mina míagadzro nu vevitɔwo me ake:

• NSF nye dɔléle si mebɔ kura o, vevietɔ le amesiwo ŋu ayikudɔ le gome, eye ate ŋu atso MRI ƒe vovototodedeameme ƒe atike xoxo aɖewo gbɔ.
• Womeka nya ta tso NSF dɔlékui yeye aɖeke ŋu fifia o. Esia tso atike yeye siwo le dedie wu zazã kple ɖɔktawo ƒe nyanya gbɔ.
• Dzesi vevitɔwoe nye ŋutigbalẽ ƒe ƒoƒo, tete, ʋuʋudedi, kple ƒunukpeƒewo ƒe kuxiwo.
• Ne ayikudɔ le ŋuwò la, kpɔ egbɔ be yeƒo nu tso amadede siwo nèzã kple afɔku si le NSF me ŋu na wò ɖɔkta hafi nàwɔ MRI.
• Naneke meli woavɔ̃ o, elabena le mɔnu siwo li fifia gome la, afɔku sia le sue ŋutɔ. Ke hã, enyo ɣesiaɣi be nànɔ ŋudzɔ.

Wò lãmesẽ dzi kpɔkpɔe nye nu vevitɔ kekeake. Ne nyabiase alo dzimaɖitsitsi aɖe le asiwò la, mègahe atikewɔlawo ƒe aɖaŋuɖoɖo didi ɖe megbe gbeɖe o.

` Nephrogenic systemic fibrosis, ayikudɔ, MRI scan, gadolinium, ŋutigbalẽdɔlélewo, GBCAs, dɔléle siwo mebɔ o