Nukae nye POEMS Syndrome? Ðe nèdi be yeanya nu tso esia hã ŋua?

Èse POEMS Syndrome ŋkɔ kpɔa? Esia nye nɔnɔme si mebɔ o si ŋu ƒã hafi wosea nu tsoe. Gake ele vevie be míanya nu vi aɖe tso eŋu elabena ate ŋu akpɔ ŋusẽ ɖe míaƒe ŋutilã ƒe ɖoɖo geɖe dzi zi ɖeka. Kpuie ko la, enye nɔnɔme sesẽ aɖe si do ƒome kple míaƒe ʋu. Egbea, míaƒo nu tso nusi POEMS Syndrome nye, eƒe dzesiwo, alesi wokpɔnɛ, kple nenye be atike aɖe li ŋu.

Nuka tututue nye POEMS Syndrome?

Enyo, mina míakpɔ nusi POEMS Syndrome nye ɖa. Esia nye ʋumedɔ si mebɔ ŋutɔŋutɔ o. Ʋumenugbagbevi ƒomevi aɖe si woyɔna be plasma cells le míaƒe ŋutilã me. Ne POEMS ƒe dɔlélea dzɔ la, ʋumenugbagbevi siawo ma hedzina ɖe edzi le mɔ si mesɔ o nu, eye womate ŋu aɖu wo dzi o. Plasme lãmenugbagbevi siawo siwo mesɔ o ɖea protein tɔxɛ aɖe ɖe míaƒe ʋu me. Woyɔa esia be monoclonal protein, alo M-protein kpuie. Fifia àte ŋu akpɔe le susu me, alo? Ne ʋumenugbagbevi dzĩ siawo siwo mesɔ o, siwo nye M-protein, dzi ɖe edzi akpa le ʋua me la, ate ŋu agblẽ nu le míaƒe lãmekawo kple míaƒe ŋutinuwo ŋu.

Woɖe ŋkɔ POEMS tso dɔléle sia ƒe dzesi vevi atɔ̃awo ƒe ŋɔŋlɔdzesi gbãtɔwo me:

• P - Polyneuropathy: Esia fia lãmekawo ƒe gbegblẽ le ŋutilã bliboa me. Le HAKPEKPEWO me la, nusiwo gblẽ sia ate ŋu ana nàse veve alo seselelãme bubu siwo meɖea dzi ɖi o (abe ʋuʋudedi, dzobibi, kple bubuawo ene) nanɔ wò afɔwo, abɔwo, afɔkpodziwo, kple asiwo me.
• O - Organomegaly: Esia fia be ŋutinu ememetɔwo va lolona le mɔ si mesɔ o nu. Ame si ŋu POEMS le ƒe ŋutinuwo abe aklã, dɔgbo, kple ʋuka siwo me ʋu sina tona ene ate ŋu akeke.
• E - Endocrinopathy: Kpuie ko la, esia nye lãmetsiŋusẽ ƒe kuxi. Le POEMS me la, lãmetsiŋusẽ agbɔsɔsɔme si míaƒe lãmenugbagbeviwo ƒe dɔwɔwɔ ɖe go ate ŋu anye esi mesɔ o. Woate ŋu ado lãmetsi aɖewo ɖe go fũ alo le agbɔsɔsɔ sue aɖe me.
• M - Monoclonal protein (M-protein): Esia nye protein tɔxɛ si ƒoa ƒu ɖe ʋu me le POEMS me. Ne plasma cell ɖeka wɔ eɖokui ƒe kɔpi (clones) geɖe la, lãmenugbagbevi mawo dometɔ ɖesiaɖe tsɔa M-protein sia kpena ɖe ʋua ŋu. Mlɔeba la, M-protein ƒe agbɔsɔsɔ si le ʋua me dzina ɖe edzi ŋutɔ.
• S - Ŋutilã ƒe tɔtrɔ: Ame siwo ŋu POEMS le ate ŋu akpɔ ŋutigbalẽ ƒe tɔtrɔ vovovowo, abe ŋutigbalẽ ƒe viviti dodo kple ŋutigbalẽ ƒe ƒoƒo ene.

Wogayɔa POEMS ƒe dɔlélea be ƒumeŋuɖui ƒe dɔléle , Crow-Fukase ƒe dɔléle , PEP ƒe dɔléle , kple Takatsuki ƒe dɔléle .

Amekae ate ŋu axɔ POEMS ƒe dɔlélea wu?

POEMS ƒe dɔlélea nye dɔléle si mebɔ kura o. Ame ʋɛ aɖewo koe wògblẽa nu le le xexeame godoo. Wokpɔnɛ zi geɖe le amesiwo xɔ tso ƒe 50 va ɖo ƒe 60. Ate ŋu adze ŋutsu kple nyɔnu siaa dzi, gake edze abe ebɔ ɖe ŋutsuwo me wu ene.

Nukae nye POEMS ƒe dɔlélea ƒe dzesiwo?

Abe alesi míegblɔe va yi ene la, ŋɔŋlɔdzesi siwo le ŋkɔ POEMS me fia dzesi vevi aɖewo. Eyae nye be, Polyneuropathy, Organomegaly, Endocrinopathy, M-protein ƒe kɔkɔ, kple ŋutigbalẽ ƒe tɔtrɔe nye dzesi vevitɔwo. Amesiame kloe si ŋu POEMS le la ƒe ahɔhɔ̃mekawo ƒe dɔléle kple M-protein ƒe dzidziɖedzi le eŋu. Dzesi bubuwo ate ŋu ato vovo tso ame ɖeka gbɔ yi bubu gbɔ.

Dzesi siwo ahɔhɔ̃mekawo ƒe dɔléle si nye polyneuropathy hena vɛ

Dzesi siwo lãmeka ƒe gbegblẽ sia hena vɛ lae bɔ wu le POEMS me. Zi geɖe la, afɔwo kple afɔwo dzie wosea vevea le wu. Gake ɣeaɖewoɣi la, ate ŋu agblẽ nu le abɔwo kple asiwo ŋu. Alesi nàte ŋu ase le ɖokuiwò me ne nɔnɔme sia le ŋuwòe nye esi:

• Gbɔdzɔgbɔdzɔ
• Ʋuʋudedi
• Gbɔdzɔgbɔdzɔ
• Prickling / Pins-kple-aŋewo ƒe seselelãme
• Dzobibi ƒe seselelãme

Organomegaly - ŋutinu ememetɔwo ƒe lolome

Nɔnɔmetata siwo ɖɔktawo wɔna ate ŋu ade dzesii ne ŋutinu siawo lolo:

• Aklã (Aklã - `(Aklã ƒe lolome)`) .
• Aɖuɖɔtoe (Splenomegaly) .
• Lãmetsiŋusẽ ƒe ʋukawo (Lymph nodes - `(Lymphadenopathy)`) .

Endocrinopathy - lãmetsiŋusẽ ƒe kuxiwo

Lãmetsiŋusẽ ƒe kuxi vevitɔ si dona tso POEMS me enye gbɔdɔdɔ ƒe lãmetsiwo ƒe agbɔsɔsɔ dzi ɖeɖe kpɔtɔ. Woyɔa gbɔdɔdɔ ƒe lãmetsi siawo be ``Testosterone`` le ŋutsuwo me eye ``Estrogen`` le nyɔnuwo me. Tsɔ kpe ɖe eŋu la, àte ŋu akpɔ dzesiwo abe:

• Kuxi siwo le sukli ƒe agbɔsɔsɔ le ʋu me dzi ɖuɖu me (e.g. suklidɔ) .
• Lãmetsiŋusẽ ƒe kuxiwo (e.g. Hypothyroidism) .
• Addison ƒe dɔléle (Adrenal insufficiency - `(Addison ƒe dɔléle)`)

Ŋutsuwo ate ŋu akpɔ vidzidzi dzi ɖeɖe kpɔtɔ kple no ƒe lolome (Gynecomastia).

Le nyɔnuwo gome la , dzinukpɔkpɔ ate ŋu atɔ (`(Amenorrhea)`), no ate ŋu alolo. Le fufɔɣi la, lãmetsi si nye `(Prolactin)`, si kpena ɖe notsi wɔwɔ ŋu, ateŋu awɔ wòagbɔ eme. Eyata ate ŋu adzɔ be notsi nado le no me ne mèfɔ fu o gɔ̃ hã.

M-Protein si dzi ɖe edzi

Nu vevi aɖe si ɖe dzesi le POEMS ŋue nye M-protein ƒe agbɔsɔsɔ si dzina ɖe ʋua me. M-protein ƒe agbɔsɔsɔ sia ate ŋu ana dɔdzẽwo nado le ʋua me. Azɔ hã, le M-protein ƒe agbɔsɔsɔ si sɔ gbɔ ta la, wò...Ƒuwo ate ŋu asẽ eye woasẽ (ƒumeŋuɖui) .

Ŋutilã ƒe tɔtrɔ

Ŋutilã ƒe tɔtrɔ vovovowo ate ŋu adzɔ, abe:

• Ŋutilã si do viviti wu
• Ŋutilã si le kpekpem wu
• Asibidɛ ɣiwo
• Taɖa ƒe tsitsi ɖe wò mo kple afɔwo dzi ƒe dzidziɖedzi
• Ʋuka siwo le abe cherry suewo ene ƒe tsitsi le akɔta ƒe ŋutigbalẽ dzi

Dzesi bubuwo

Tsɔ kpe ɖe esia ŋu la, woate ŋu akpɔ dzesi bubuwo:

• Asiwo kple afɔwo ƒe vuvu
• Lolo dzi ɖeɖe kpɔtɔ le susu aɖeke manɔmee
• Vevesese le ƒuwo kple ƒunukpeƒewo ŋu
• Nukpɔkpɔ ƒe kuxiwo
• Yagbɔgbɔ sesẽ
• Ɖeɖiteameŋu
• Asrã

Dɔléle aɖe ate ŋu anɔ ame aɖewo siwo ŋu POEMS ƒe dɔlélea le hã ŋu, si woyɔna be Castleman Disease (CD), si gblẽa nu le ʋuka siwo me ʋu sina tona ŋu. Ne Castleman Dɔléle ƒe dzesiwo le ŋuwò la, wò ɖɔkta ate ŋu asusui hã be POEMS.

Nukae hea POEMS ƒe dɔlélea vɛ?

Ne POEMS le ŋuwò la, èkpɔa dzesi kple ŋusẽkpɔɖeamedzi vovovowo le ʋumenugbagbeviɣidɔ si nye monoclonal plasma cell disorder ta . Kpuie ko la, ʋumenugbagbevi dzĩ si mesɔ o la wɔa eɖokui ƒe kɔpi geɖe akpa. Zi alesi lãmenugbagbevi siawo sɔ gbɔe la, zi nenemae woate ŋu agblẽ nu le lãmekawo ŋui. Lãmenugbagbevi siawo tsɔa M-protein kpena ɖe ʋua ŋu, si wɔnɛ be M-protein ƒe agbɔsɔsɔ si le ʋua me dzina ɖe edzi. Lãmenugbagbevi siawo siwo sɔ gbɔ wu kple M-protein ye gblẽa nu le ŋutilãa ƒe ɖoɖo vovovowo ŋu.

Gake dzɔdzɔmeŋutinunyalawo menya nusita tututu ʋumenugbagbevi dzĩ siawo dzea tsitsi gɔme le mɔ si mesɔ o nu le gɔmedzedzea me o.

Numekulawo kpɔe be protein aɖe si woyɔna be Vascular Endothelial Growth Factor (VEGF) ate ŋu akpɔ gome le eme. VEGF sɔ gbɔ ɖe ame akpa gãtɔ siwo ŋu POEMS ƒe dɔlélea le ƒe ʋu me. Wogale numekuku wɔm tso ƒomedodo si le VEGF kple POEMS ƒe dɔlélea dome ŋu.

Aleke wokpɔa POEMS ƒe dɔlélea? (Dɔléle ƒe dzesi) .

Wò ɖɔkta abia wò gbã tso wò atikewɔwɔ ŋutinya kple dzesi siwo le ŋuwò fifia ŋu. Emegbe, woawɔ ŋutilãmedɔdada atsɔ akpɔe ɖa be POEMS ƒe dɔlélea ƒe dzesiwo le wo ŋu hã.

Tsɔ kpe ɖe eŋu la, ɖɔkta ate ŋu awɔ dodokpɔ geɖe hã, abe:

• Ʋu kple aɖuɖɔ dodokpɔ: Dodokpɔ siawo ate ŋu akpe ɖe ŋuwò nàkpɔe ɖa be M-protein alo VEGF sɔ gbɔ ɖe wò ʋu alo aɖuɖɔ me hã. Woate ŋu alé ŋku ɖe ʋumenugbagbevi dzĩwo ƒe xexlẽme si mesɔ o alo ʋumenugbagbevi siwo dzena abe ɖe womesɔ o hã ŋu. Esiawo ate ŋu anye HAKPƆKPƆWO ƒe dzesiwo.
• Nɔnɔmetatawo dodokpɔ: Dodokpɔwo abe X-ray kple CT scan ene ate ŋu aɖee afia ne wò ƒuwo ƒo tititi alo wosẽ. Tɔtrɔ siawo ate ŋu ava ne M-protein ƒe agbɔsɔsɔ dzi ɖe edzi.
• Ƒumeŋuɖui me lãmenugbagbeviwo ɖeɖe: Esia ate ŋu anya ne ʋumenugbagbevi dzĩ siwo ƒe dzedzeme mesɔ o le wò ƒumeŋuɖui me, alo ne ʋumenugbagbeviɣiwo sɔ gbɔ akpa.
• Electromyogram (EMG): EMG nye dodokpɔ si wotsɔ dzidzea lãmekawo ƒe dɔwɔwɔ. Ate ŋu akpe ɖe wò ɖɔkta ŋu wòakpɔ ahɔhɔ̃mekawo ƒe dɔléle si nye polyneuropathy.

Le wò dzesiwo nu la, wò ɖɔkta ate ŋu awɔ dodokpɔ bubuwo hã, abe gbɔgbɔ dodokpɔ, echocardiogram, alo lãmenugbagbeviwo ƒe dodokpɔ ene.

Ne wokpɔ dɔléle aɖe si woyɔna be Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) , le ŋuwò la, wò ɖɔkta ate ŋu ado wò hã akpɔ be POEMS ƒe dɔlélea le ŋuwò hã.

Aleke wokpɔa POEMS ƒe dɔlélea gbɔe alo daae?

Atike aɖeke meli na POEMS ƒe dɔlélea o. Gake atikewɔwɔ ate ŋu akpe ɖe ame ŋu wòaɖu dzesiawo dzi ahakpɔ wo dzi. Atikewɔwɔ ƒe tiatia aɖewoe nye:

• Kekeli ƒe dɔdamɔnu: Esia bia be woahe keklẽŋusẽ gbogbo aɖe ayi ʋumenugbagbevi dzĩ siwo mesɔ o gbɔ be wòatsrɔ̃ wo.
• Chemotherapy: Wozãa atike siwo wua kansa, siwo woyɔna hã be ``Chemotherapy,'' tsɔ wua ʋumenugbagbevi dzĩ siwo mesɔ o ƒe tsitsi alo ɖea woƒe tsitsi dzi kpɔtɔna. Atikewɔwɔ na POEMS sɔ kple atikewɔwɔ na multiple myeloma. Dɔdamɔnu siawo wɔa dɔ ŋutɔ eye zi geɖe la, womehea nugbegblẽ le ame ŋu vevie o.
• Autologous stem cell transplant: Dɔwɔwɔ sia tsɔa lãmenugbagbevi siwo le lãmesẽ me ɖɔlia wò ʋumenugbagbevi dzĩ siwo mesɔ o. Stem cells nye lãmenugbagbevi siwo tsina zua lãmenugbagbevi tsitsiwo abe plasma cells ene. Le amedodo sia me la, wò ɖɔkta ɖea lãmenugbagbevi siwo le lãmesẽ me dometɔ aɖewo ɖa le wò ŋutilã me gbã. Emegbe, wozãa atikewɔmɔnu alo keklẽŋusẽdɔdamɔnu tsɔ tsrɔ̃a ʋumenugbagbevi dzĩ siwo mesɔ o. Le atikewɔwɔa megbe la, wogatsɔa lãmenugbagbevi siwo woɖe ɖa la dea wò ŋutilã me. Emegbe wotsina zua ʋumenugbagbevi dzĩ siwo le lãmesẽ me.
• Lãmesẽfefe: Ne azɔlizɔzɔ sesẽ na wò le ahɔhɔ̃mekawo ƒe dɔléle ta la, atikewɔwɔ sia ate ŋu akpe ɖe ŋuwò.

Tsɔ kpe ɖe eŋu la, ɖɔkta ate ŋu aŋlɔ atikewo abe steroids be wòaɖe dzesiawo dzi akpɔtɔ kple atike siwo naa tsinyegoe (tsitikewo) be woaɖe abi dzi akpɔtɔ.

Kuxi kawoe do ƒome kple POEMS ƒe dɔlélea?

Le POEMS ƒe dɔlélea gome la, lãmekawo ƒe gbegblẽ kple gbɔdzɔgbɔdzɔ ate ŋu adzi ɖe edzi le ɣeyiɣi aɖe megbe. Ate ŋu ana hã be ʋuʋu le teƒeteƒewo nasesẽ. Ne tsi geɖe ƒo ƒu ɖe lãkusi gbɔ alo akɔta ƒe do me la, ate ŋu ana akɔta nase veve eye gbɔgbɔ nasesẽ.

Gake ɖo ŋku edzi be, .Atikewɔwɔ dzidzedzetɔe ate ŋu atɔ te lãmekawo ƒe gbegblẽ alo ana wòagbɔdzɔ. Ate ŋu akpe ɖe ame ŋu hã be wòaɖe dzesi bubuwo dzi akpɔtɔ. Lãmetsiŋusẽ ƒe gbegblẽ gɔ̃ hã ate ŋu ahaya vivivi le ɣeyiɣi aɖe megbe.

Ðe afɔku aɖewo li na POEMS ƒe dɔlélea?

Fifia womede dzesi afɔku siwo ate ŋu ana POEMS ƒe dɔlélea nadze ame dzi o.

Ðe woate ŋu axe mɔ ɖe POEMS ƒe dɔlélea nua?

Nublanuitɔe la, womate ŋu axe mɔ ɖe POEMS ƒe dɔlélea nu o.

Nukae nye amesiwo ŋu POEMS ƒe dɔlélea le ƒe ŋgɔdonya?

Wò lãmesẽ nɔ te ɖe nu geɖe dzi, siwo dometɔ aɖewoe nye wò ŋutilã ƒe akpa siwo ŋu wògblẽa nu le, alesi wokpɔa dɔlélea dzea sii kabakaba eye wodzea atikewɔwɔ gɔme, kple alesi nèwɔa nu ɖe ​​atikewɔwɔ ŋui.

Ele vevie be woaxɔ atike na POEMS. POEMS ƒe dɔlélea ate ŋu ade ame ƒe agbe afɔku me ne womewɔ atike nɛ o. Le go bubu me la, atikewɔwɔ dzidzedzetɔe siwo gblẽa ʋumenugbagbevi dzĩ siwo mesɔ o la ate ŋu akpe ɖe ŋuwò nànɔ agbe didi wu. Tsɔ kpe ɖe eŋu la, atikewɔwɔ ate ŋu aɖe dɔlélea ƒe dzesiwo dzi akpɔtɔ eye wòana wò agbenɔnɔ nanyo ɖe edzi.

Ame akpa gãtɔ siwo ŋu POEMS le ƒe agbetsitsi le mama dedie nu anɔ abe ƒe 14 ene. Ema fia be ame siwo ade afã nɔa agbe mede ƒe 14 o, evɔ afã mamlɛa ya nɔa agbe didi wu. Wò agbenɔƒe nɔ te ɖe wò dɔlélea ŋuti nuteƒekpɔkpɔ kple atikewɔwɔ tɔxɛ dzi.

Bia wò ɖɔkta tso wò etsɔme ŋu abe amesi le agbe kple POEMS ƒe dɔlélea ene.

Ɣekaɣie wòle be nàkpɔ ɖɔkta le POEMS ƒe dɔlélea ŋu?

Ne èkpɔ dzesi aɖe si do ƒome kple POEMS ƒe dɔlélea, vevietɔ gbɔdzɔgbɔdzɔ le abɔwo kple afɔwo me , yi ɖɔkta gbɔ enumake.

Nya kawoe wòle be mabia nye ɖɔkta tso POEMS ƒe dɔlélea ŋu?

Àte ŋu abia nya siawo tɔgbe:

• Aleke gbegbee nye nɔnɔmea nu sẽe?
• Atikewɔwɔmɔnu kawoe le asinye?
• Nukae wòle be mawɔ be maɖe eƒe nugbegblẽ le ame ŋu dzi akpɔtɔ alo akpɔ wo gbɔ?
• Kpekpeɖeŋunadɔ kawoe li nam?
• Ðe wòhiã be makpɔ ɖɔkta si bi ɖe ʋumenugbagbevi dzĩwo ƒe dɔlélewo me be wòafia mɔ nye atikewɔwɔa?

Ɣekaɣie mate ŋu atrɔ ayi nye dɔwɔna siwo mewɔna ɖaa dzi ne POEMS ƒe dɔlélea le ŋunye?

POEMS ƒe dɔléle ate ŋu akpɔ ŋusẽ ɖe wò ŋutete be nàwɔ wò gbesiagbedɔwo dzi. Wò ɖɔkta aɖe alesi nɔnɔme sia akpɔ ŋusẽ ɖe wò gbesiagbegbenɔnɔ dzii me na wò.

Ðe POEMS ƒe dɔlélea nye dɔléle si dɔlélenutsiŋutete wɔna?

POEMS nye dɔléle si nye paraneoplastic syndrome.Menye dɔléle si dɔlélenutsiŋutete ŋutɔ hena vɛ o. Paraneoplastic syndrome nye dzesi siwo woƒo ƒu tso atikewɔwɔ me nɔnɔme aɖe si le ete gbɔ. Le POEMS me la, kuxi si gbɔ wòtsoe nye be ʋumenugbagbevi dzĩ siwo mesɔ o wɔa M-protein fũ akpa le ʋua me (si nye ʋumenugbagbeviɣidɔ si nye monoclonal plasma cell disorder). POEMS ƒe dzesiwo tsoa ʋumenugbagbevi dzĩ siwo mesɔ o kple M-protein si gblẽa nu le ŋutilã ƒe lãkusiwo ŋu gbɔ.

Ðe POEMS ƒe dɔlélea sɔ kple multiple myeloma?

Multiple myeloma nye kansa si gblẽa nu le ʋumenugbagbevi dzĩwo ŋu. POEMS ƒe dɔlélea nye dzesi siwo tso ʋumenugbagbevi dzĩ siwo mesɔ o kple M-protein ƒe dzidziɖedzi gbɔ la ƒe ƒuƒoƒo. POEMS ƒe dɔlélea ƒe agbetsitsi nyo wu agbenɔƒe si wokpɔ mɔ na le multiple myeloma me.

Gake zi geɖe la, atikewɔmɔnu siwo wozãna tsɔ daa POEMS kple multiple myeloma la sɔ. Dzesi aɖewo hã ate ŋu asɔ kple wo nɔewo.

POEMS ƒe dɔlélea nye dɔléle si wokpɔna le ame ŋu si sesẽ ŋutɔ. Ðewohĩ axɔ ɣeyiɣi aɖe hafi wò ɖɔkta nakpɔe be POEMS ƒe dɔlélea gbɔe wò dzesiawo tso ke menye nɔnɔme bubu aɖe gbɔe wòtso o. Ne wonya kpɔ dɔlélea le ŋuwò ko la, wɔ dɔ kplikplikpli kple wò atikewɔlawo ƒe ƒuƒoƒoa be nànya atikewɔmɔnu siwo ana gbɔdzɔe wò wu tso wò dzesiawo me. Bia wò ɖɔkta tso habɔbɔ alo kpekpeɖeŋunaha siwo kpena ɖe ame ɖekaɖekawo kple ƒome siwo le dɔlélewo abe POEMS ƒe dɔléle ene gbɔ kpɔm ŋu.

Gbedasi si Wotsɔ Yi Aƒeme

Enyo, eyata míeƒo nu geɖe tso POEMS Syndrome ŋu egbea. Nu vevitɔe nye be nàse egɔme be esia nye nɔnɔme si mebɔ o, gake wòsẽ . Ate ŋu akpɔ ŋusẽ ɖe míaƒe ŋutilã ƒe ɖoɖo geɖe dzi.

• Woɖe ŋkɔ POEMS tso Eŋlisigbe me ŋkɔ siwo nye dzesi vevi atɔ̃ (lãmeka ƒe dɔléle, ŋutinuwo ƒe lolome, lãmetsiŋusẽ ƒe kuxiwo, M-protein ƒe dzidziɖedzi, kple ŋutigbalẽ ƒe tɔtrɔ) ƒe ŋɔŋlɔdzesi gbãtɔwo me.
• Nusi koŋ gbɔ esia tsonae nye ʋumenugbagbevi dzĩ siwo mesɔ o kple M-protein si wowɔna.
• Togbɔ be womate ŋu adae bliboe o hã la, atikewɔmɔnu nyui aɖewo li siwo dzi woato aɖu dzesiawo dzi ahana agbenɔnɔ nanyo ɖe edzi.
• Ele vevie ŋutɔ be woakpɔ dɔlélea ahadze edada gɔme kaba .

Ne dzesi siawo dometɔ aɖe le ŋuwò la, taflatse di atikewɔlawo ƒe aɖaŋuɖoɖo. Mègatsi dzodzodzoe o, ne nyatakaka nyuitɔ kple atikewɔlawo ƒe kpekpeɖeŋu le asiwò la, àte ŋu anɔ te ɖe nɔnɔme sia nu.

` POEMS syndrome, ʋumenugbagbeviɣiwo, lãmekawo ƒe gbegblẽ, lãmetsiŋusẽ ƒe kuxiwo, M-protein, ŋutigbalẽ ƒe tɔtrɔ, ʋumenugbagbevi dzĩwo