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Nuka tututue nye SIADH?
Kpuie ko la, SIADH nye nɔnɔme si me wò ŋutilã wɔa lãmetsi si nye Antidiuretic Hormone (ADH) fũ akpa, alo le mɔ si mesɔ o nu. Wogayɔa ADH lãmetsi sia be Vasopressin. ADH lãmetsi sia dzɔna le hypothalamus me le míaƒe ahɔhɔ̃ me. Le ema megbe la, wodzranɛ ɖo ɖe megbeƒu ƒe lãkusi me eye woɖea asi le eŋu yia ŋutilãa me ne ehiã. Azɔ, mina míakpɔ nu vevi siwo ADH lãmetsi sia kpena ɖe míaƒe ŋutilã ŋu ɖa:- Tsi kple sodium ( dze ) ƒe agbɔsɔsɔ si le míaƒe ʋu me ƒe dadasɔ.
- Ekpena ɖe ame ŋu wòɖua ʋu ƒe sisi dzi .
- Ekpena ɖe ayikuwo ŋu wòwɔa dɔ nyuie.
Ameka ŋue SIADH ate ŋu agblẽ nu le wu?
Le nyateƒe me la, ame sia ame ate ŋu axɔ SIADH. Gake nɔnɔme sia ƒe afɔkua dzina ɖe edzi ne ame tsi. Le goawo katã me la, nɔnɔme sia si woyɔna be SIADH bɔ wu le:- Le amesiwo le hayahayam tso amekoko me le kɔdziwo dome la, esia ate ŋu adzɔ le tsi siwo wonana le amekoko vɔ megbe, atike aɖewo, kple alesi ŋutilãa wɔa nui ɖe vevesese kple nuteɖeamedzi ŋu ta.
- Le amesiwo ŋu lãkusi me dɔdzẽ le dome, vevietɔ amesiwo ŋu ƒomevi aɖe si woyɔna be Small Cell Lung Cancer ( SCLC )'' le.
Aleke gbegbee woyɔa nɔnɔme sia be SIADH?
SIADH nye nɔnɔme si bɔ ŋutɔ. Hyponatremia (sodium si bɔbɔ ɖe ʋu me) si ŋu míeƒo nu tsoe va yi lae nye Electrolyte ƒe dadasɔmakpɔmakpɔ si bɔ wu si wokpɔna le dɔnɔ siwo woxɔ ɖe kɔdzi me. SIADH ye nye nusi koŋ gbɔ Hyponatremia tsona.
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Check Availability →Aleke SIADH hea hyponatremia vɛ?
Tsɔe be tsikɔ le wuwòm vevie. Nukae wò ŋutilã wɔna? Enaa dzesi ŋutilã be wòaɖe lãmetsi si nye ADH ɖa. Emegbe ayikuawo ɖea tsi si dona le aɖuɖɔ me dzi kpɔtɔna, eye ŋutilãa léa tsi ma ɖe asi. Ne èno tsi, ne wò tsikɔwuame dzi ɖe kpɔtɔ la, ŋutilãa dzudzɔa ADH dodo, eye ayikuwo gadzea tsi dodo gɔme le aɖuɖɔ me le mɔ si sɔ nu. Esiae nye nusi wowɔna le mɔ si sɔ nu. Ke hã, le ame geɖe siwo ŋu SIADH le gome la, lãmetsi si nye ADH ƒe dodo dzi meɖena kpɔtɔna nyuie le tsinono vɔ megbe gɔ̃ hã o. Eyata woƒe aɖuɖɔ me yɔ fũ ŋutɔ (si fia be tsi mesɔ gbɔ o eye gbeɖuɖɔ sɔ gbɔ ɖe wo me). Esia nana tsi ƒoa ƒu ɖe ŋutilãa me. Ne tsi sia ƒo ƒu la, woɖea nuwo abe sodium ene le ʋua me. Ɣemaɣie sodium ƒe agbɔsɔsɔ le ʋu me dzi ɖena kpɔtɔna, si woyɔna be Hyponatremia. Le SIADH ƒe nɔnɔme aɖewo me la, ne tsi sɔ gbɔ ɖe ŋutilãa me la, woɖea dzesi na ayikuwo be woaɖe dze (sodium) geɖe ɖe aɖuɖɔ me. Esia nye nu bubu si hea hyponatremia vɛ.Nukae nye SIADH ƒe dzesiwo?
Ne SIADH le ŋuwò la, wò aɖuɖɔ ƒoa ƒu ŋutɔ. Ema fia be gbeɖuɖɔwo sɔ gbɔ akpa eye tsi hã mesɔ gbɔ akpa o. Esi wònye be zi geɖe la, wò ŋutilã meɖea tsi doa goe kple aɖuɖɔ o ta la, tsi si le wò ʋu me dzina ɖe edzi. Esia nana nuwo abe sodium ene nɔa wò ʋu me.Sodium ƒe agbɔsɔsɔ si bɔbɔ ɖe ʋu me (hyponatremia) ye nye nu vevitɔ si gbɔ SIADH ƒe dzesiwo tsona .Zi geɖe la, sodium ƒe agbɔsɔsɔ si bɔbɔ vie gɔ̃ hã mehea dzesi gã aɖeke vɛ o. Gake ne sodium ƒe agbɔsɔsɔ le sue alo le sue ŋutɔ la, dzesiwo abe esiawo ene ate ŋu ado mo ɖa:
- Lãmetsiwo ƒe ʋuʋu alo gbɔdzɔgbɔdzɔ. Kpɔe ɖa le susu me be yese le ye ɖokui me abe ɖe yeƒe afɔwo le ʋuʋum ko ene.
- Aɖuɖɔtoe kple ʋuʋudedi .
- Taɖuame .
- Kuxi siwo le dadasɔ me, si ate ŋu ana ame nadze anyi ɣeaɖewoɣi.
- Susu me tɔtrɔwo, abe susu ƒe dɔwɔwɔ sesẽ, ŋkuɖoɖonudzi ƒe gbɔdzɔgbɔdzɔ, kple/alo nuwɔna wɔnukuwo ene.
- Le nɔnɔme sesẽwo me la, alɔ̃madɔmadɔ alo alɔ̃madɔmadɔ ate ŋu adzɔ.
Nukawoe hea SIADH vɛ?
Zi geɖe la, atikewɔwɔ me nɔnɔme bubu aɖe gbɔe SIADH tsona. Domenyiŋusẽfianu si nye SIADH (si fia be wotsɔnɛ toa dzidzimewo me) mebɔ kura o.Etso domenyiŋusẽfianu ƒe tɔtrɔ le Vasopressin 2 (V2) receptors me le ayiku me. Nɔnɔme kple nusiwo gbɔ wòtsona siwo nana SIADH dzɔna zi geɖe la dometɔ aɖewoe nye esi:- Kansa ƒomevi aɖewo: Dɔdzẽ aɖewo ate ŋu awɔ woawo ŋutɔ ƒe ADH lãmetsi. Esia ate ŋu ana ADH nagbɔ eme le ŋutilãa me, si ana SIADH nadzɔ. Lãmenugbagbevi suewo ƒe lãkusi me dɔdzẽ (SCLC) ye nye kansa ƒomevi si bɔ wu si wɔa ADH le mɔ sia nu. Tsɔ kpe ɖe eŋu la, kansa abe lãmenugbagbevi suewo ƒe kansa siwo dona le lãkusi godo, ta kple kɔ me kansa, kple ʋeʋẽ ƒe ahɔhɔ̃mekawo hã ate ŋu ahe SIADH vɛ.
- Central Nervous System (CNS) ƒe Kuxiwo: Ahɔhɔ̃ kple aklãe nye míaƒe lãmekawo. Nu ɖesiaɖe si mesɔ o le ɖoɖo sia me, abe ʋusɔgbɔdɔ, ʋu si dona le ahɔhɔ̃a me, dɔlékuiwo xɔxɔ, abixɔxɔ, alo ƒã hafi susu ƒe dɔmawɔmawɔ nyuie ene ate ŋu ahe SIADH vɛ.
- Atike aɖewo: Atike aɖewo ateŋu adzi lãmetsi si nye ADH ƒe dodo alo dɔwɔwɔ ɖe edzi. Eyata SIADH ateŋu adzɔ. Le kpɔɖeŋu me, atike aɖewo na asrãdɔ, blanuiléle ƒe atikewo, kansa ƒe atikewo, kple dzidɔ, suklidɔ, kple ʋusɔgbɔdɔ ƒe atike aɖewo.
- Amekoko le atike si naa alɔ̃dɔdɔ ame me: Woate ŋu atsɔ SIADH asɔ kple amekoko. Esia ate ŋu atso susu kple ŋutilã me nuteɖeamedzi si ŋutilãa tona gbɔ.
- Aklãdɔ: Aklãdɔ, vevietɔ aklãdɔ (si dɔlékuiwo, dɔlékuiwo, alo yɔmekpe hena vɛ) ate ŋu ahe SIADH vɛ. Numekulawo meka ɖe nusitae wòdzɔna alea dzi haɖe o.
- Lãmetsiŋusẽ ƒe gbɔdzɔgbɔdzɔ: Nɔnɔme eve siwo woyɔna be Hypopituitarism (pituitary gland si mewɔa dɔ nyuie o) kple Hypothyroidism (thyroid gland si mewɔa dɔ nyuie o) ateŋu ahe SIADH vɛ.
Aleke wowɔna dea dzesi SIADH?
Ne hyponatremia (sodium si mebɔ o le ʋu me) ƒe dzesiwo le ŋuwò la, wò ɖɔkta awɔ wò ŋutilã dodokpɔ bliboe. Woalé ŋku ɖe wò tsi ƒe nɔnɔme hã ŋu. Esia le vevie be woate ŋu akpɔ dɔlélea nyuie. Woalé ŋku ɖe eŋu be tsi vɔ le ŋuwò, tsi le ŋuwò akpa, alo wòsɔ pɛpɛpɛ hã. Dodokpɔ nyuitɔ ɖeka aɖeke meli si woatsɔ anya SIADH o. Togbɔ be dodokpɔ aɖewo li siwo ate ŋu akpɔ ADH ƒe agbɔsɔsɔ le wò ʋu me hã la, ate ŋu axɔ kwasiɖa eve hafi emetsonuwo nagatrɔ ava. Eyata anɔ eme be wò ɖɔkta aɖe gbe be nàwɔ dodokpɔ bubuwo atsɔ akpɔe ɖa be ʋumenugbagbeviɣidɔ le ame ŋu hã, abe:- Nusiwo Wotsɔ Ða Nuwo ƒe Dɔwɔnawo Ŋuti Dɔwɔha (CMP).
- Ʋu ƒe osmolality dodokpɔ.
- Aɖuɖɔ ƒe Osmolality Dodokpɔ.
- Aɖuɖɔ me sodium kple potassium dodokpɔ.
- Toxicology Screens na atike aɖewo.
Aleke wowɔa atike na SIADH?
SIADH dada nɔ te ɖe nusi gbɔ wòtso dzi. Le kpɔɖeŋu me, ne dɔdzẽ aɖe le ŋuwò si le ADH wɔm la, wò ɖɔkta ate ŋu aɖo aɖaŋu be nàwɔ dɔ na wò atsɔ aɖee ɖa. Ne atike aɖe gbɔe dɔlélea tso la, wò ɖɔkta ate ŋu atrɔ atikeawo ƒe agbɔsɔsɔme alo aŋlɔ atike bubu na wò. Le SIADH ƒe nɔnɔmewo katã me la, afɔɖeɖe gbãtɔe nye be nàɖe tsi agbɔsɔsɔme si nàno dzi akpɔtɔ. Esia kpena ɖe ŋuwò be wò ŋutilã megaléa tsi fũ o. Wò ɖɔkta agblɔ tsi agbɔsɔsɔme si wòle be nàno gbesiagbe (si me tsi, kɔfi, tii, kple nunono siwo me sukli le hã le). Ne hyponatremia ƒe dzesi sesẽwo le ŋuwò (abe tɔtɔ, alɔ̃madɔmadɔ ene) la, ke enye atikewɔwɔ kpata. Zi geɖe la, wotsɔa saline (dzetsi si wotsɔna toa ʋuka me) si wotsɔ dea ʋuka me daa dɔ na esia le kɔdzi. Àte ŋu ahiã atike hã be woatsɔ axe mɔ ɖe ADH lãmetsiŋusẽa ƒe ŋusẽkpɔɖeamedzi ɖe wò ayiku dzi nu. Emegbe ayikuawo xɔa dzesiwo eye wodzea tsi si sɔ gbɔ ɖe ŋutilãa me to aɖuɖɔ me ɖeɖe ɖe go gɔme.Ðe woate ŋu axe mɔ ɖe SIADH nua?
Esi wònye be nu geɖewo li siwo gbɔ SIADH tsona ta la, zi geɖe la, esesẽna be woaxe mɔ ɖe enu. Ne ètsi dzi be SIADH alo hyponatremia ate ŋu anɔ ye ŋu la, ƒo nu kple wò ɖɔkta.Nukae nye SIADH ƒe ŋgɔdonya?
Mɔkpɔkpɔ na SIADH nɔ te ɖe nusi gbɔ wòtso dzi. Nya nyuiae nye be nusiwo gbɔ SIADH tsona dometɔ geɖe nye esiwo woate ŋu atrɔ eye/alo woate ŋu ada wo. Acute hyponatremia, si dzɔna kabakaba, le gaƒoƒo si mede gaƒoƒo 48 o me la, nye afɔku wu hyponatremia si dona vivivi le ɣeyiɣi aɖe megbe. Hyponatremia si nɔa anyi didi do ƒome kple ahɔhɔ̃mekawo ƒe kuxiwo (e.g., dadasɔ ƒe bu, ŋkuɖoɖonudzi ƒe bu). Ne SIADH nu sẽ eye sodium ƒe agbɔsɔsɔ le ʋua me ɖiɖi akpa la, nusiwo gbɔna ate ŋu adzɔ:- Ame ƒe susu ƒe dɔwɔwɔ, susumenuwo, alo alɔ̃madɔmadɔ.
- Ahɔhɔ̃ ƒe Ʋuʋudedi.
- Ku.
Ɣekaɣie wòle be nàkpɔ ɖɔkta le SIADH ŋu?
Ne èkpɔ dzesi siwo nye hyponatremia, abe lãmekawo ƒe ʋuʋu kple dadasɔ ƒe kuxiwo ene la, ƒo nu kple wò ɖɔkta. Esi wònye be nu vovovowo ate ŋu ahe dzesi siawo vɛ ta la, anɔ eme be wò ɖɔkta awɔ dodokpɔ vovovowo.Ne ʋumenugbagbeviɣidɔ sesẽ ƒe dzesiwo le ŋuwò, abe tɔtɔ, tagbɔdɔ, alo alɔ̃madɔmadɔ ene la, yi kɔdzi si te ɖe ŋuwò kaba ale si nàte ŋui.SIADH nye dɔléle si bɔ ŋutɔ si ate ŋu atso nu geɖe gbɔ. Zi geɖe la, edzea ame siwo woxɔ ɖe kɔdzi xoxo la dzi. Gake ne èkpɔ SIADH ƒe dzesiwo, abe ʋuʋudedi alo susu ƒe tɔtrɔ ene la, ele vevie be nàƒo nu kple ɖɔkta.
Nu vevitɔ kekeake siwo wòle be wòanɔ susu me na wò (Take-Home Message) .
Enyo, eyata mele mɔ kpɔm be fifia miese SIADH si ŋu míeƒo nu tsoe egbea la gɔme nyuie wu.- SIADH nye nɔnɔme si me ŋutilã léa tsi ɖe te eye wòɖea sodium dzi kpɔtɔna le ʋu me le lãmetsi ADH ƒe wɔwɔ fũ ta.
- Susu geɖewo ate ŋu anɔ esia ta; nuwo abe kansa, atike aɖewo, amekoko, lãkusidɔ, kple bubuawo ene.
- Dzesiawo ate ŋu anye ʋuʋudedi, ʋuʋudedi, taɖuame, kple susu ƒe tɔtrɔ . Le nɔnɔme sesẽwo me la, alɔ̃madɔmadɔ kple susu ƒe dɔwɔwɔ ate ŋu adzɔ.
- Atikewɔwɔ ate ŋu anye tsi dzi ɖuɖu, atike si gbɔ wòtso, kple dze alo atike nana ne ehiã .
- Nu vevitɔe nye be, ne dzesi siawo le ŋuwò la, mègatsi dzodzodzoe o eye nàdi atikewɔlawo ƒe aɖaŋuɖoɖo enumake. To mɔ sia dzi la, àte ŋu anya nusi tututu gblẽ eye nàdze atikewɔwɔ si hiã la gɔme.
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