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Living with Uncontrolled Body Movements? What You Need to Know About Austedo

Dr. Priya Sammani (MBBS)
Medically Reviewed by Dr. Priya Sammani (MBBS) ✓ Medically Reviewed
📅 Updated: Oct 23, 2026 • ⏱ 8 min read • Editorial Policy
Living with Uncontrolled Body Movements? What You Need to Know About Austedo
Table of Contents ▾

Do you ever feel like your own body is moving without your permission? It can feel very scary and helpless when your hands, face, or body start twitching, jerking, or twisting while you try to talk, eat, or sign your name.

These sudden and uncontrolled movements make everyday life hard. They can also make you feel worried about being around other people. If you or someone you love deals with these challenges, you are not alone, and help is available.

Today, we will look at a medicine called Austedo. We will explain how it works, how to use it safely, and what side effects you might experience along the way.

Key Takeaways at a Glance

  • What it treats: Austedo helps control involuntary body movements caused by Huntington's disease and tardive dyskinesia.
  • How it works: It balances chemical messengers in your brain to calm down extra signaling to your muscles.
  • Slow and steady start: Your doctor will start you on a low dose and slowly increase it over weeks to find the best fit.
  • Safety first: Always share your full list of current medicines, vitamins, and supplements with your doctor before starting.
  • Patience is key: It takes time for the medicine to work fully in your body, so keep in close touch with your care team.
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Two Main Conditions That Cause Uncontrolled Body Movements

Doctors prescribe Austedo primarily to treat two specific medical conditions that cause involuntary muscle movements. Let us explore both conditions in simple terms.

First is chorea due to Huntington's disease. This is an inherited health condition that runs in families. Over time, nerve cells in the brain break down, which leads to trouble with thinking, emotions, and body control. Chorea refers to the sudden, jerky, and twisting movements that happen without your control.

Second is tardive dyskinesia (TD). This condition also causes repeated, involuntary movements in your face, eyes, mouth, hands, and feet. The most common cause is taking certain medicines for mental health conditions, such as antipsychotics, over a long period of time.

How Austedo Works Inside Your Body

Your brain acts like a massive message center. It uses tiny nerve cells to send messages to your muscles telling them when to move and when to stop. Special chemical messengers called neurotransmitters carry these signals back and forth.

Think of neurotransmitters like mail carriers. They carry important letters and instructions from your brain directly to your muscles.

Dopamine is one of these main message carriers. In both chorea and tardive dyskinesia, these dopamine messengers send way too many messages to your muscles. Your muscles receive constant signals that say "move, move, move," which causes your body to shake and twist.

Austedo works by slowing down these extra messages. It helps calm the traffic in your brain so your muscles stop receiving so many accidental signals.

How to Use This Medicine Properly

Pharmacies supply Austedo in two main tablet types. Your doctor will choose the right one for your specific daily routine.

  • Regular tablets: You usually take these by mouth one or two times every day with food.
  • Austedo XR tablets: This is an extended-release tablet. It releases the medicine slowly into your body throughout the entire day, so you generally take it just once a day.

Your doctor will always start you on a very low starting dose. After that, they will raise your dose little by little each week until they find your ideal maintenance dose that controls your symptoms best. Always follow your doctor's exact instructions for changing your dose.

Important Tips When Taking Your Medicine

  • Take regular Austedo tablets with food. You can take Austedo XR tablets with or without food.
  • Never cut, crush, or chew the tablets. Swallow them whole with a full glass of water.
  • If you take Austedo XR, your body absorbs the medicine while leaving an empty shell behind. You might sometimes notice this empty shell in your bowel movements. This is completely normal and safe.
  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and stay on your normal schedule. Never take two doses at the exact same time to make up for a missed one. Ask your doctor if you feel unsure.

How to Know If the Medicine Is Working

You will not see results right away on day one. It usually takes anywhere from several weeks to a few months for your involuntary movements to slow down noticeably.

Because your doctor needs time to find the exact dose that works for your unique body, you must practice patience during your treatment journey.

If you feel like your symptoms are not getting any better, or if they seem to be getting worse, talk openly with your doctor right away. They may adjust your dose or explore other helpful treatment options.

Possible Side Effects and How to Handle Them

Just like any medicine, Austedo can cause side effects in some people, though not everyone experiences them. The table below lists common side effects and simple ways to manage them safely.

Side Effect How to Manage It
Drowsiness and fatigue Avoid driving or using heavy machinery until you know how this medicine affects your daily alertness.
Diarrhea Drink plenty of water and clear fluids to prevent dehydration. Eat plain foods like rice and bananas. Tell your doctor if it becomes severe.
Dry mouth Sip water often throughout the day. Try breathing through your nose instead of your mouth, and chew sugar-free gum for relief.
Trouble sleeping Avoid coffee, tea, and other caffeinated drinks in the afternoon and evening. Keep a steady bedtime routine and limit phone use before sleep.
Cold-like symptoms Mild stuffy nose or throat irritation usually passes in a few days. Rest and warm tea help. Call your doctor if symptoms linger.

Other Medicines That Do Not Mix Well with Austedo

This is a very important safety section. Certain medicines do not mix well with Austedo and must be avoided or used with extreme caution.

Medicines You Must Never Take Together

  • MAOIs (Monoamine Oxidase Inhibitors): These are specific medicines used for depression or Parkinson's disease.
  • Reserpine: An older medicine once used for high blood pressure.
  • Tetrabenazine and Valbenazine: These are other movement disorder medicines similar to Austedo. Taking them together can sharply increase your risk of severe side effects.

Medicines That Require Extra Caution

  • CYP2D6 inhibitors: These include common medicines like bupropion and fluoxetine for depression, or quinidine for heart rhythms. Taking them with Austedo can cause the medicine levels in your blood to rise too high. Your doctor may need to lower your Austedo dose if you take these.
  • Antipsychotics: Taking these mental health medicines with Austedo can raise your risk of muscle stiffness, parkinsonism symptoms, or severe restlessness.
  • Other sleepy medicines and alcohol: Austedo can already make you feel sleepy. Mixing it with allergy pills like Benadryl or other sedatives will make your drowsiness much worse. Do not drink alcohol while taking Austedo.

When to Seek Emergency Medical Help

Call 911 (US/Canada), 999 (UK), or go to your nearest Emergency Department right away if you experience severe allergic reactions (trouble breathing, swelling of your face or throat), sudden high fever with rigid muscles and confusion, or thoughts of self-harm.

💡 Take-Home Message

  • Austedo is a specialized prescription medicine designed to manage involuntary body movements caused by Huntington's disease and tardive dyskinesia.
  • Always take this medicine exactly as your doctor prescribes. Never change your dose or stop taking it on your own.
  • Because it takes time for your body to adjust and respond, remain patient as your doctor finds your ideal dose over several weeks.
  • Tell your doctor about all other medicines, vitamins, and supplements you use to keep your treatment safe.
  • Reach out to your doctor right away if you notice severe side effects or feel that your symptoms are getting worse.

❓ FAQ

Frequently Asked Medical Questions (FAQ)

Evidence-based clinical answers to common patient questions

Can Austedo cure Huntington's disease or tardive dyskinesia completely?

No, Austedo does not cure the underlying condition. Instead, it acts as a helpful management tool designed to reduce and control the sudden involuntary muscle movements so you can feel more comfortable in your daily life.

What should I do if I accidentally take too much Austedo?

If you or someone else takes too much Austedo, you should contact your local poison control center or seek medical help right away. An overdose can cause severe drowsiness, balance issues, and acute restlessness.

Is it safe to drink alcohol while taking Austedo?

No, you should avoid drinking alcohol while taking Austedo. Alcohol can increase side effects like extreme sleepiness, dizziness, and poor coordination.

Can I stop taking Austedo suddenly if my symptoms improve?

You should never stop taking Austedo abruptly without talking to your doctor first. Stopping suddenly can cause your involuntary movements to return quickly or become much worse.

How does Austedo XR differ from regular Austedo tablets?

Regular Austedo tablets are typically taken twice daily with food, whereas Austedo XR is an extended-release version designed to release medicine into your body slowly over 24 hours, usually requiring just one dose per day.

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Verified Scientific & Medical References (PubMed / WHO)

✓ Peer-Reviewed Sources
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⚠️ Important: Medical articles and information on Nirogi Lanka are strictly for educational and awareness purposes and do not substitute professional medical advice, diagnosis, or treatment. Always consult a qualified physician for any medical concerns.