Do you also often get heartburn? Do you feel like you have acid in your throat when you eat or drink? This is a very annoying problem for some people. Most of the time, we call this ``( GERD )`` or the disease of stomach acid coming back into the esophagus. So, today we are going to talk about a medicine that is given in very limited quantities for such conditions, but only when other treatments have not been successful. That is the oral liquid medicine called ``Cisapride``.
What is Cisapride? Why is it so special?
Simply put, Cisapride is a medication used to treat heartburn and gastroesophageal reflux disease (GERD) . However, the important thing to note here is that this medication is not for everyone, all the time.
In fact, because this medication can have some serious risks , doctors only decide to prescribe it if lifestyle changes and other medications fail to provide relief. Remember, this is only used as a last resort .
Another special fact is that this medicine has not been available in pharmacies since August 2000. If you need this medicine, your doctor will have to register with the pharmaceutical company and meet special criteria to give you this medicine. This means that this is not just a medicine for a disease. If you want to know more about this, the manufacturer has provided a toll-free number at (877) 795-4247 (this is probably a number for use in the United States).
This medicine may also be used for other conditions, so if you have any questions, it's best to ask your doctor or pharmacist .
A well-known brand name for this medicine is `(Propulsid)`.
Things you need to tell your doctor before taking this medicine!
Before your doctor prescribes Cisapride, it is important to know your complete medical history. This is because some people with certain medical conditions may not be able to take this medicine. Therefore, you should tell your doctor if you have any of the following conditions:
- Eating disorders, for example, anorexia (not eating properly due to lack of appetite ) or bulimia ( purging after eating).
- Heart disease or heart failure .
- Heart rhythm problems.
- Heart valve problems.
- If you have ever had low levels of calcium, potassium, or magnesium in your body.
- Kidney disease.
- Liver disease.
- Lung disease.
- Stomach bleeding, blockage, or ulceration.
- If you have ever had an unusual or allergic reaction to Cisapride, other medicines, foods, artificial colours or preservatives.
- If you are pregnant or trying to get pregnant.
- If you are a breastfeeding mother.
It is very important for your own safety to tell the doctor without hiding these things!
How do you use this medicine correctly?
This is an oral suspension. If your doctor prescribes this for you, you should take it exactly as directed on the label.
- Shake the bottle well before using.
- When measuring your medicine, you should use a spoon or cup that has a special measuring cup. If you don't have one, ask your pharmacist for one. Don't use regular teaspoons, which are not accurate.
- This medicine should be taken on an empty stomach . That is, at least 15 minutes before eating or before going to bed at night.
- Do not take more medication than the doctor prescribed, or take it more often than prescribed.
Should this medicine be given to small children?
You should talk to your pediatrician about giving this medicine to children. Special care may be required.
What if I take too much medicine? (`Overdosage`)
If you think you have taken too much medicine, call a poison control center or the nearest hospital emergency room immediately.
Important note: This medicine has been prescribed for you only. Do not share it with anyone else for any reason.
What to do if you miss a dose of medication?
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Never take a double dose or an extra dose.
Other medications that may interact with this medicine (Interactions)
This is a section that you should read very carefully. Cisapride is a drug that can cause serious problems when taken with certain other medications. Therefore, it is important to tell your doctor what other medications you are taking.
Do not take Cisapride with any of the following medications:
- Alfuzosin `(alfuzosin)`
- Antiviral medicines for HIV or AIDS
- Apomorphine `(apomorphine)`
- Aprepitant
- Arsenic trioxide `(arsenic trioxide)`
- Some antibiotics: for example, ciprofloxacin, clarithromycin, dalfopristin;quinupristin, erythromycin, gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin, norfloxacin, ofloxacin, pentamidine, sparfloxacin, telithromycin, troleandomycin
- Some types of cancer medications: for example, daunorubicin, doxorubicin
- Some medications for depression, anxiety, or other mental illnesses: for example, clozapine, haloperidol, isoniazid, pimozide, risperidone, ziprasidone
- Some medications for sexual dysfunction: For example, sildenafil, tadalafil, vardenafil
- Some medications for fungal infections: For example, fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
- Some medicines for irregular heart beat: for example, amiodarone, bretylium, disopyramide, dofetilide, dronedarone, flecainide, ibutilide, procainamide, propafenone, quinidine, sotalol
- Chloroquine `(chloroquine)`
- Cimetidine `(cimetidine)`
- Conivaptan
- Cyclobenzaprine
- Cyclosporine
- Danazol `(danazol)`
- Diltiazem `(diltiazem)`
- Dolasetron `(dolasetron)`
- Droperidol `(droperidol)`
- General and local anesthetics
- Grapefruit juice - This is very important!
- Halofantrine
- Hawthorn `(hawthorn)` (herbal extract)
- Imatinib `(imatinib)`
- Isoniazid (a medicine for tuberculosis, also mentioned here)
- Methadone
- Mifepristone `(mifepristone)`
- Nicardipine `(nicardipine)`
- Octreotide
- Other medicines that affect the heart rhythm (cause an abnormal heartbeat - prolong the `QT interval`)
- Palonosetron `(palonosetron)`
- Phenothiazines: For example, chlorpromazine, fluphenazine, mesoridazine, perphenazine, prochlorperazine, promethazine, thioridazine, trifluoperazine
- Quinine
- Ranolazine
- Sodium phosphates
- Tacrolimus
- Verapamil `(verapamil)`
- Zafirlukast `(zafirlukast)`
- Zileuton `(zileuton)`
This medicine may also interact with the following drugs:
- Diuretics (medicines that cause more urine to be excreted)
- Insulin (a medicine for diabetes)
This list may not include all possible interactions. Therefore, tell your doctor about all medications, herbs, vitamins, and supplements you are taking. Also, tell your doctor if you smoke, drink alcohol, or use illegal drugs. Some things can interact with your medication.
What should I be careful about when taking this medicine?
See your doctor regularly to check your health and make sure the medicine is working. It is important to make some changes to your lifestyle for this medicine to work properly.
- Don't eat a lot at one time, eat small meals .
- When you sleep, elevate your head about 6 to 8 inches.
- Reduce or eliminate fatty foods, chocolate, alcohol, smoking, caffeine (like coffee), and carbonated drinks (like soda) . These can aggravate your GERD.
Urgent warning! If you experience fainting spells, rapid heartbeat, or irregular heartbeat, stop taking this medicine immediately and see your doctor.
Another important thing: Do not drink grapefruit juice while taking this medication. Grapefruit juice can increase the risk of serious side effects from this medication.
What are the possible side effects of this medicine?
There are some side effects that you should tell your doctor or healthcare professional as soon as possible if they occur:
- Allergic reactions: skin rash, itching or hives, swelling of the face, lips or tongue.
- Breathing problems.
- Fainting, feeling weak, and falling.
- Rapid or irregular heartbeat.
- Unusually weak and tired.
- Vomiting.
Side effects that usually do not require medical advice, but should be reported to your doctor if they persist or are bothersome:
- Diarrhea or constipation.
- Headache.
- Nausea.
- Stomach pain.
- Stuffy nose.
This list may not include all side effects. Talk to your doctor for medical advice about side effects. You may also report side effects to the FDA (number: 1-800-FDA-1088, this is a number in the United States).
Where should I keep this medicine?
- Keep it out of the reach of children.
- Store at room temperature (between 15 and 30 degrees Celsius / 59 and 86 degrees Fahrenheit).
- Protect from light.
- Throw away unused medicine that has passed its expiration date.
Note: This article is a summary only. It may not contain all the details. If you have any further questions about this medicine, talk to your doctor, pharmacist, or healthcare provider.
Finally, things to remember
Okay, so we've talked a lot about Cisapride. The most important thing is that this is a very special, restricted medication. It's not something you can just go to a pharmacy and get.
- Use only as directed by your doctor.
- Tell your doctor about every medication you take and every illness you have.
- Lifestyle changes (very important for GERD).
- If you notice any serious side effects, tell your doctor immediately.
- Never share this medicine with others.
Your health is as important to you as it is to us. Therefore, always be aware and responsible.
` Cisapride, GERD, heartburn, Propulsid, oral suspension, medication side effects, drug interactions, stomach inflammation, gastroesophageal reflux, drug side effects
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