Me yasa cutar hanta da ake kira PBC ta fi yawa a cikin mata? (Primary Biliary Cholangitis - PBC)

Shin kun taɓa jin labarin cutar hanta ta PBC? Wataƙila ba ku san sunan ba. Amma shin kun san cewa mutane tara cikin goma da ke fama da wannan matsalar mata ne? Wannan abin mamaki ne, ko ba haka ba? To me yasa wannan cutar ta shafi mata? Menene dalilin hakan? A yau, za mu yi magana game da wannan a sauƙaƙe, ta hanyar da za ku iya fahimta.

Bari mu fara gani, menene PBC?

To, wannan ɗan suna ne na kimiyya, amma abin da ke faruwa abu ne mai sauƙi. PBC, wanda ke nufin Primary Biliary Cholangitis, cuta ce da tsarin garkuwar jikinmu ke shiga ta hanyar da ba ta dace ba kuma tana kai hari ga hantarmu. Muna kiran irin waɗannan cututtuka da cututtukan da ke haifar da garkuwar jiki. Ka yi tunanin, tsarin garkuwar jikinmu kamar rundunar da ke kare ƙasa ne. Aikin wannan rundunar shine yaƙi da ƙwayoyin cuta da ƙwayoyin cuta da ke fitowa daga waje da kuma ceton mu daga cututtuka. Amma wani lokacin wannan rundunar tana yin kuskure kuma tana fara kai hari ga mutanen da ba su da laifi a ƙasarsu. Wani abu makamancin haka yana faruwa a PBC. Tsarin garkuwar jikinmu yana kai hari ga ƙananan hanyoyin bile a cikin hantarmu. Waɗannan hanyoyin bile suna da matukar muhimmanci na bututun da ke ɗauke da bile da hanta ke samarwa zuwa hanji. Lokacin da waɗannan hanyoyin suka lalace, bile ba ya gudana yadda ya kamata kuma yana taruwa a cikin hanta, yana lalata hanta a hankali.

To me yasa hakan ya fi shafar mata?

Yanzu bari mu duba amsar babbar tambayar da kowa ke da ita. Masu bincike har yanzu ba su sami wani dalili na gaskiya ba game da wannan. Duk da haka, sun yi imanin cewa manyan abubuwa uku ne ke taimakawa wajen hakan.

1. Tasirin hormones

Ka sani, jikin mata ya bambanta da jikin maza. Babban dalilin hakan shine hormones. Musamman ma, hormone estrogen yana taka muhimmiyar rawa a kowane mataki na rayuwar mace. Ka yi tunani game da shi, tare da zagayowar al'ada ta wata-wata, musamman ma lokacin da mace ta daina al'ada, wanda ke faruwa tsakanin shekaru 40-60, akwai manyan canje-canje a matakan wannan hormone estrogen. Waɗannan canje-canjen hormones suna shafar yadda ƙwayoyin garkuwar jikinmu ke aiki kai tsaye. Hormon ɗin estrogen na iya ƙarfafa tsarin garkuwar jiki sosai. Wato, kunna "rundunar" da muka yi magana a kai a baya. Lokacin da wannan ya faru, haɗarin kai hari ga ƙwayoyin halittarsa ​​yana ƙaruwa. Za mu iya tunanin wannan haɗin tunda PBC ya fi yawa a tsakanin mata a wannan rukunin shekaru.

2. Kwayoyin cuta a cikin hanji

Wannan na iya zama sabon abu a gare ku. Triliyoyin ƙwayoyin cuta masu kyau da marasa kyau suna rayuwa a cikin hanjinmu. Wannan al'umma ta ƙwayoyin cuta tana da matuƙar muhimmanci ga lafiyarmu. Bincike ya gano cewa mutanen da ke ɗauke da kwayar halittar da ke haifar da PBC suna da nau'ikan ƙwayoyin cuta daban-daban a cikin hanjinsu fiye da wasu. Hakanan suna da matakan ƙwayoyin cuta mafi girma waɗanda galibi ke da alaƙa da cututtukan fitsari (UTIs). Don haka wannan yana nuna cewa wasu cututtukan ƙwayoyin cuta da rashin daidaituwa a cikin ƙwayoyin cuta na hanji na iya taimakawa wajen haɓaka PBC ta hanyar lalata tsarin garkuwar jiki.

3. Tasirin kwayoyin halitta da gado

"Shin wannan cuta ce ta gado?" za ka iya yin mamaki. Haka ne, a wani ɓangare, kwayoyin halitta suna taka rawa.

• Tsakanin kashi 1% zuwa 9% na mutanen da ke dauke da cutar PBC suna da wani dan uwa da ke dauke da cutar.
• Idan ɗaya daga cikin tagwaye biyu masu kama da juna ta kamu da cutar PBC, akwai kashi 63% na yiwuwar ɗayan ma ya kamu da cutar.

Mafi muhimmanci fiye da duk wannan shine shigar kwayar halittar X. A taƙaice dai, mata suna da kwayar halittar X guda biyu (XX), yayin da maza kuma suna da kwayar halittar X guda ɗaya da kwayar halittar Y guda ɗaya (XY). Bincike ya nuna cewa mata masu dauke da kwayar halittar PBC ba su da kwayar halittar X guda ɗaya ko kuma suna da wasu canje-canje a cikin kwayar halittar X a wasu ƙwayoyin jikinsu. Waɗannan canje-canjen na iya shafar aikin kwayoyin halittar da ke cikin tsarin garkuwar jiki, wanda hakan ke ƙara haɗarin kamuwa da wannan cuta ta garkuwar jiki.

Shin zai yiwu a zauna lafiya da PBC?

Hakika eh! PBC cuta ce da za a iya magance ta da kyau tare da ingantaccen magani da canje-canjen salon rayuwa. Da zarar an gano cutar da wuri, da sauƙi a shawo kan lalacewar hanta. Abu mafi mahimmanci lokacin rayuwa da wannan cutar shine a ci gaba da dangantaka mai kyau da likitanka . Yana da mahimmanci a sha maganin da ya rubuta a kan lokaci, a halarci asibitoci a kan lokaci. Bugu da ƙari, ta hanyar cin abinci mai kyau, guje wa barasa gaba ɗaya, da kuma yin motsa jiki mai kyau kamar yadda likitanka ya ba da shawara, za ku iya rayuwa mai kyau. Yanzu akwai magunguna masu kyau don magance alamun cutar, kamar gajiya mai yawa da kaikayi fata. Don haka yi magana a fili da likitanka game da shi. PBC, Babban Ciwon Hanta, Cututtukan Hanta, Lafiyar Mata, Cututtukan Kai-tsaye, Estrogen, Hormones, Kwayoyin Halitta, Cutar Hanta a Mata Sinhala, akmawe leda