E aʻo kākou e pili ana i kēia lāʻau lapaʻau kūikawā no ke koko a me ka puʻuwai? (Aldosterone Antagonists)

Loaʻa iā ʻoe ke koko kiʻekiʻe, a i ʻole ka mea a mākou e ʻike ai he 'kaomi'? A i ʻole he paʻa wai kou a he pehu kou mau wāwae ma muli o kahi maʻi e like me ka hōʻeha puʻuwai? A laila ua kuhikuhi paha kāu kauka iā ʻoe i kahi lāʻau lapaʻau kūikawā. ʻO ia ke ʻano lāʻau lapaʻau a mākou e kamaʻilio ai ma kēia ʻatikala i kēia lā, me ka maʻalahi a me ke akahai. Kāhea mākou i kēia mau Aldosterone Antagonists.

I ka ʻōlelo maʻalahi, he aha kēia mau Aldosterone Antagonists?

ʻAe, e hoʻomaopopo kākou i kēia ma kēia ʻano. Loaʻa iā kākou ʻelua mau ʻāpana liʻiliʻi i loko o ko kākou kino i kapa ʻia ʻo nā kelepa adrenal. Hoʻopuka kēia i kahi hormone i kapa ʻia ʻo aldosterone. ʻO ka hana nui o kēia hormone ka hoʻomalu ʻana i ke koko ma ka mālama ʻana i ka paʻakai a me ka wai i loko o ke kino i ka wā e pono ai. ʻAʻole kēia he pilikia no ke kanaka maʻamau.

Akā e noʻonoʻo, inā ua loaʻa i kekahi ke koko kiʻekiʻe, a inā paha he nui ka wai i loko o ko lākou kino ma muli o ka maʻi puʻuwai, e hoʻonui wale kēia hormone aldosterone i ke kūlana.

ʻO ia kahi e kōkua mai ai kahi papa o nā lāʻau lapaʻau i kapa ʻia ʻo Aldosterone Antagonists iā mākou. Hana kēia mau lāʻau lapaʻau ma ke ālai ʻana i ka hana o ka hormone aldosterone (ʻo ke ʻano o ka antagonist ka hana kūʻē iā ia). ʻO ia ke kumu i kapa ʻia ai kēia papa o nā lāʻau lapaʻau ʻo 'potassium-sparing diuretics'.

He aha nā ʻano lāʻau lapaʻau nui ma kēia māhele?

Aia kekahi mau ʻano lāʻau lapaʻau Aldosterone Antagonist i kuhikuhi pinepine ʻia e nā kauka. Ua ʻike paha ʻoe i kēia mau inoa.

Pehea e hana ai kēia lāʻau lapaʻau i loko o ke kino?

He mea maʻalahi loa ia. Ke lawe ʻoe i kahi lāʻau Aldosterone Antagonist, hele ia a ālai i nā mea loaʻa e ʻae ai i ka hormone aldosterone e hoʻopaʻa i nā ʻāpana o ke kino. He aha ka mea e hana ʻia?

ʻAʻole hiki i ka hormone aldosterone ke hoʻopaʻa i ka paʻakai a me ka wai i loko o ke kino. No laila, hoʻomaka ko mākou mau puʻupaʻa e hoʻokuʻu i ka paʻakai a me ka wai keu ma o ka mimi. ʻO ka mea kūikawā e pili ana i kēia, ʻoiai e hoʻokuʻu ana i kēlā paʻakai a me ka wai, pale ia i ke kino mai ka nalowale ʻana o ka mineral potassium koʻikoʻi.

He aha nā kūlana nui e hoʻohana ʻia ai nā Aldosterone Antagonists?

Paipai nā kauka i kēia ʻano lāʻau lapaʻau ma ke ʻano he lāʻau lapaʻau no kekahi maʻi, akā, no kekahi mau maʻi.

• Ka Hāʻule ʻana o ka Puʻuwai: Ke nāwaliwali ka puʻuwai, hōʻiliʻili ka wai i loko o ke kino (edema) a hoʻoulu i ka pehu ʻana i nā wāwae a me nā māmā. Kōkua kēia lāʻau lapaʻau i ka wehe ʻana i kēlā wai keu a hoʻēmi i ke kaumaha ma ka puʻuwai.
• Ke koko kiʻekiʻe: Kōkua kēia lāʻau lapaʻau i ka hoʻokele ʻana i ke koko kiʻekiʻe i paʻakikī ke kaohi me nā lāʻau lapaʻau ʻē aʻe.
• Maʻi Puʻupaʻa Mau Loa: Hoʻohana ʻia kēia mau mea e mālama i nā maʻi puʻupaʻa, ʻoiai nā mea e hele mai me ka maʻi diabetes.
• Hyperaldosteronism: He kūlana kēia kahi e hana nui ai ke kino i ka hormone aldosterone. He mea nui kēia lāʻau lapaʻau e mālama i kēia.
• ʻEdema i hoʻokumu ʻia e ka maʻi akepaʻa: Hāʻawi ʻia kēia mau mea e kāohi i ka paʻa ʻana o ka wai ma muli o ka maʻi akepaʻa.
• Ka pae potassium haʻahaʻa i loko o ke koko: Hāʻawi ʻia kēia lāʻau lapaʻau no kēia kūlana no ka mea kōkua ia i ka mālama ʻana i ka pae potassium i loko o ke kino.
• ʻAki: Paipai pū kekahi mau dermatologists iā Spironolactone no ka ʻaki no ka mea e hoʻoponopono ana i ka hana o kekahi mau hormones.

Nā pōmaikaʻi a me nā hopena ʻaoʻao o kēia mau lāʻau lapaʻau

E like me nā lāʻau lapaʻau āpau, hiki i kēia mau mea ke loaʻa nā pōmaikaʻi a me kekahi mau hopena ʻaoʻao.

Nā pono nui

• Hoʻolōʻihi i ke ola o nā poʻe maʻi me ka maʻi puʻuwai.
• Loaʻa iā lākou ka ikaika hou aku e hoʻoikaika kino a hana i nā hana o kēlā me kēia lā.
• Hoʻemi i ka pono no ka hoʻokipa ʻana i ka haukapila.
• Hoʻemi nui i ka pilikia o ka make koke e pili ana i nā maʻi puʻuwai.

Nā hopena ʻaoʻao hiki ke loaʻa

Ke lawe ʻoe i kēia lāʻau lapaʻau, hiki iā ʻoe ke mimi pinepine ma mua o ka maʻamau no ka mea he diuretic ia. He mea maʻamau kēia. Eia kekahi, hiki ke hana ʻia nā mea ʻē aʻe.

• Kuke
• ʻO ka poniuniu (vertigo)
• ʻEha poʻo (ʻeha poʻo)
• Ka maʻi pākī
• Ke kiʻekiʻe o ka pae potassium i loko o ke koko: ʻO kēia ka mea nui e hopohopo ai. He kiʻekiʻe loa kēia pilikia i ka poʻe me ka maʻi puʻupaʻa. No laila, e nānā mau ke kauka i ka pae potassium ma ka hana ʻana i nā hoʻokolohua koko.

Nā hopena ʻaoʻao e pili ana iā Spironolactone

Ma muli o ka launa pū ʻana o ka lāʻau Spironolactone me kekahi mau hormones ʻē aʻe i loko o ke kino (androgen a me progesterone), hiki i kekahi poʻe ke ʻike i kēia mau mea:

• Ka hoʻonui ʻana o ka umauma (Gynecomastia) i nā kāne a me nā wahine.
• Ka hana pono ʻole o ka moekolohe i nā kāne (nā pilikia erection).
• ʻO ke kahe koko ʻana o ka wahine ma hope o ka menopause.

No kēia mau kumu, makemake paha kekahi poʻe e hoʻololi i ka Eplerenone. Akā e hoʻomanaʻo, ʻo kāu kauka wale nō ke hoʻoholo i ka lāʻau lapaʻau kūpono iā ʻoe .

I ka manawa hea e kamaʻilio ai me kāu kauka

Inā loaʻa iā ʻoe kekahi mau hopena ʻaoʻao i ka wā e lawe ana i kēia lāʻau lapaʻau, mai hoʻōki i ka lawe ʻana iā ʻoe iho. E kamaʻilio koke me kāu kauka. Hiki paha iā ia ke hoʻololi i ka nui o ka lāʻau a hoʻololi paha iā ʻoe i kahi lāʻau lapaʻau ʻē aʻe.

Eia kekahi, inā ʻaʻole e hoʻomaikaʻi kāu mau ʻōuli ma hope o ka hoʻohana ʻana i ka lāʻau lapaʻau no kekahi mau pule, e hoʻomaopopo i kāu kauka e pili ana i kēlā.

Eia kekahi, inā ʻoe e lawe nei i kēia lāʻau lapaʻau, e ʻoluʻolu e nīnau i kāu kauka ma mua o ka inu ʻana i ka wai huaʻai a i ʻole ka hoʻohana ʻana i nā mea paʻakai ʻē aʻe, no ka mea, aia paha i loko o kekahi o kēia mau mea ka potassium.