ʻOiai ke lohe kākou i ka huaʻōlelo kanesa, he makaʻu nui ko kākou a pau i loko o ko kākou mau manaʻo. Akā i kēia lā, ua holomua nui ka ʻepekema lapaʻau. Ua loaʻa nā ʻano lapaʻau kupaianaha e hakakā ai i nā hunaola kanesa. I kēia lā e kamaʻilio kākou e pili ana i kekahi ʻano lapaʻau kūikawā. I ka ʻōlelo maʻalahi, hoʻohana ʻia kēia mau mea e hoʻopilikia i ka meaʻai, ʻo ia hoʻi, ka lako koko, o nā puʻupuʻu kanesa a hoʻolohi i ko lākou ulu ʻana.
He aha kēia mau mea hoʻopale Angiogenesis?
I mea e hoʻomaopopo ai i kēia, e lawe kākou i kahi laʻana liʻiliʻi. E noʻonoʻo, no ka ulu nui ʻana o kekahi lāʻau, pono ia e loaʻa mau ka wai a me nā meaʻai. Pēlā nō, no ka ulu nui ʻana o kahi puʻupuʻu a laha i nā ʻāpana ʻē aʻe o ke kino, he mea nui ka lako koko maikaʻi.
He liʻiliʻi loa ka puʻupuʻu kanesa i ka wā mua. I kēlā manawa, hoʻopili ia i nā meaʻai e pono ai mai nā ʻiʻo olakino a puni. Akā i ka wā e ulu ai ka puʻupuʻu i kahi 1-2 milimita, pono ia e hoʻomohala i kahi ʻōnaehana kīʻaha koko hou nona iho. E like me ka ulu ʻana o nā lālā hou o kahi mea kanu. Mai kēia mau kīʻaha koko hou e 'hānai' ai ka puʻupuʻu kanesa, ulu nui aʻe, a hoʻomaka e laha.
Hana kēia mau lāʻau lapaʻau kūikawā, i kapa ʻia ʻo Angiogenesis Inhibitors , ma ke kāohi ʻana i nā hunaola kanesa mai ka hana ʻana i nā kīʻaha koko hou. Hoʻolohi kēia i ka ulu ʻana o nā hunaola kanesa, a i kekahi manawa hiki i nā hunaola ke emi iho. ʻOiai ʻaʻole hiki i kēia lāʻau ke ho'ōla loa i ke kanesa, hiki iā ia ke kāohi i ka ulu ʻana o ke kanesa a hiki iā ʻoe ke noho pū me kāu poʻe aloha no kekahi manawa lōʻihi.
Pehea e hana ai kēia lāʻau lapaʻau?
Ke ālai nei kēia mau lāʻau i kahi kaʻina hana i kapa ʻia ʻo Angiogenesis e hana ʻia ana i loko o ko mākou kino. ʻO ka maʻamau, he kaʻina hana koʻikoʻi loa kēia no ko mākou kino. E noʻonoʻo he ʻeha kou ma kou lima. A laila hoʻopuka kēlā mau ʻeha i kahi hōʻailona kūikawā (hōʻailona SOS) e ʻōlelo ana, 'E kōkua mai iā mākou!'. Ma muli o kēia hōʻailona, hana ʻia nā capillaries koko hou mai nā kīʻaha koko a puni ka ʻeha, e hāʻawi ana i ka ʻeha me ka lako koko e pono ai a ho'ōla iā ia.
ʻO ka mea ʻino loa ma ʻaneʻi, ʻo ia ka hoʻohana ʻana o nā hunaola kanesa i kēia kaʻina hana maikaʻi i loko o ko kākou kino no ko lākou pono. Hoʻouna pū lākou i nā hōʻailona like a hana i nā kīʻaha koko hou e hānai iā lākou iho.
ʻO ka mea a nā Angiogenesis Inhibitors e hana ai, ʻo ia ke hoʻopilikia i kēlā ʻōnaehana hōʻailona.
- ʻO ka hōʻailona nui ma kēia ʻōnaehana hōʻailona he protein i kapa ʻia ʻo VEGF (Vascular Endothelial Growth Factor) .
- Ke hoʻopaʻa kēia protein, ʻo VEGF, i nā mea loaʻa ma ka ʻili o nā cell, hoʻouna ia i ka leka no nā kīʻaha koko hou e hana.
- Hoʻōki kēia mau lāʻau i kēia kaʻina hana ma nā ʻano like ʻole.
| Pehea e hana ai | Nā laʻana o nā ʻano lāʻau lapaʻau |
|---|---|
| Hoʻopaʻa ia i ka protein VEGF a hoʻōki iā ia mai ka hoʻopaʻa ʻana i nā mea loaʻa. | Nā lāʻau lapaʻau antibody monoclonal e like me Bevacizumab (Avastin®). |
| Hoʻopili pololei ia i ka hōʻailona mai nā mea loaʻa VEGF. | ʻO nā mea hoʻopale Tyrosine Kinase e like me Sorafenib (Nexavar®) a me Sunitinib (Sutent®). |
| Hoʻopili ia i nā ʻōnaehana hōʻailona ʻē aʻe e pili ana i ka hoʻokumu ʻia ʻana o nā kīʻaha koko i nā ʻōpū kanesa. | Nā lāʻau hoʻoponopono palekana e like me Thalidomide a me Lenalidomide (Revlimid®). |
He aha nā kūlana e hoʻohana ʻia ai kēia lāʻau lapaʻau?
ʻO ka maʻamau, ʻōlelo pinepine nā kauka i kēia lāʻau lapaʻau no nā maʻi ʻaʻai i holomua a i ʻole i hoʻi hou mai ma hope o ka lāʻau lapaʻau. Eia kekahi laʻana:
- Ka maʻi ʻaʻai lolo
- Ka maʻi ʻaʻai umauma
- Ka maʻi ʻaʻai o ka ʻōpū
- Ka maʻi ʻaʻai kolona
- Ka maʻi ʻaʻai puʻupaʻa
- Ka maʻi ʻaʻai ate
- Ka maʻi ʻaʻai māmā
- ʻO Lymphoma a me ka Myeloma Multiple
- Ka maʻi ʻaʻai pancreatic
- Ka maʻi ʻōpū
- Ka maʻi ʻaʻai thyroid
- Ka maʻi ʻōpū
Eia kekahi, hoʻohana ʻia kēia ʻano lāʻau, i kapa ʻia ʻo VEGF inhibitors, e mālama i kekahi mau maʻi maka i hoʻokumu ʻia e ka ulu ʻana o nā kīʻaha koko maʻamau ʻole i loko o nā maka.
He aha ka mea e hana ʻia i ka wā o ka mālama ʻana?
ʻAʻole hāʻawi wale ʻia kēia mau lāʻau lapaʻau. Hāʻawi pinepine ʻia lākou me ka hui pū ʻana me nā lāʻau lapaʻau ʻē aʻe e like me ka chemotherapy a i ʻole immunotherapy. I ka ʻōlelo maʻalahi, hoʻopau nā mea hoʻopaʻa angiogenesis i ka maʻi kanesa ma ka hoʻonele ʻana iā ia i kāna meaʻai, ʻoiai ʻo nā lāʻau lapaʻau ʻē aʻe e pepehi pololei i nā hunaola kanesa.
Ma muli o ke ʻano o ka lāʻau lapaʻau i hāʻawi ʻia iā ʻoe, hiki ke hāʻawi ʻia iā ʻoe ma ke ʻano he pila i hoʻokahi a ʻelua paha i ka lā, a i ʻole hiki ke hāʻawi ʻia ma ke ʻano intravenous (IV) me ka saline i hoʻokahi manawa i kēlā me kēia mau lā.
ʻO ka lōʻihi o ka mālama ʻana ma muli o ke ʻano o ka lāʻau lapaʻau i hāʻawi ʻia iā ʻoe a me kou kūlana olakino. Hoʻomau kekahi poʻe i ka lawe ʻana i ka lāʻau lapaʻau inā e hana ana. Pono kekahi e hoʻōki i ka wā ʻaʻole hiki iā lākou ke ʻae i nā hopena ʻaoʻao. Hoʻoholo ʻia kēia ma ke kamaʻilio ʻana me kāu kauka a me ke kaupaona ʻana i nā pono a me nā pōʻino o ka mālama ʻana.
He aha nā pilikia a me nā hopena ʻaoʻao?
He mea nui loa e ʻike ʻoe i nā pilikia a me nā hopena ʻaoʻao o ka hoʻohana ʻana i kēia lāʻau lapaʻau ma mua, i hiki iā ʻoe ke ʻike koke i nā loli i loko o kou kino.
Hiki i kekahi o nā hopena ʻaoʻao o kēia mau lāʻau lapaʻau ke lilo i mea weliweli, no laila he mea nui e makaʻala i kēia.
| Ka hopena ʻaoʻao/pilikia | He aha e ʻike ai |
|---|---|
| Ke koko kiʻekiʻe | He mea nui e nānā mau i kou koko i ka wā o ka mālama ʻana. |
| Ke kahe koko ʻana o loko | E makaʻala i nā hōʻailona e like me ke koko i loko o ka ʻeke a me ka ʻūlū ʻana ma kekahi wahi o ke kino. |
| Hoʻopaneʻe ka ho'ōla ʻana o ka ʻeha | Hoʻomaopopo pono ke kauka i ka hāʻawi ʻana i kēia mau lāʻau lapaʻau ma mua a ma hope paha o ke ʻoki ʻana. |
| Ka puka ʻana o ka ʻōpū | ʻOiai he mea kakaikahi loa kēia, inā loaʻa iā ʻoe ka ʻeha ʻōpū koke a koʻikoʻi, e hoʻomaopopo koke i kāu kauka. |
| Nā ʻūpā koko | He kūlana weliweli loa kēia a hiki ke alakaʻi i nā kūlana e like me ka hōʻeha puʻuwai a i ʻole ka hahau ʻana. |
| Nā hopena ʻaoʻao ʻē aʻe | Hiki nō hoʻi ke hōʻemi ʻia ka hana thyroid a me ka hōʻino ʻana o ke ake. |
He mea weliweli paha kēia, akā e nānā mau ana kāu kauka i kāu mau hoʻokolohua olakino a me ke koko, no laila hiki ke ʻike ʻia a mālama ʻia kēia mau pilikia i kahi nui.
Pehea e hiki ai iaʻu ke mālama iaʻu iho? Āhea wau e kāhea aku ai i ke kauka?
ʻO ka mea nui loa hiki iā ʻoe ke hana, ʻo ia ka ʻike pono e pili ana i nā hopena ʻaoʻao ma mua o ka hoʻomaka ʻana i kēia lāʻau lapaʻau. A laila, inā ʻike ʻoe i kekahi mau loli i kou kino, hiki iā ʻoe ke ʻike koke iā lākou a haʻi i kāu kauka. Hiki i kāu kauka ke hāʻawi iā ʻoe i nā lāʻau lapaʻau ʻē aʻe e kāohi i kēlā mau hopena ʻaoʻao, a i ʻole e hoʻololi i ka nui o ka lāʻau lapaʻau āu e lawe nei.
E ʻimi koke i ke kōkua lapaʻau inā loaʻa iā ʻoe kekahi mau hōʻailona koke a ʻano ʻē. ʻOi loa aku inā loaʻa iā ʻoe nā hōʻailona o ka hahau ʻana a i ʻole ka hōʻeha puʻuwai (e.g., ʻeha nui o ka umauma, paʻakikī ka hanu ʻana, mae wale ka maka a i ʻole nā lālā), e hele koke i ka Emergency Department (ETU) o ka haukapila kokoke loa.
Aia kekahi mau mea e hoʻōki kūlohelohe ai i kēia kaʻina hana?
ʻAe, aia kekahi mau meaʻai i nā hui e hiki ke ālai i kekahi o nā hōʻailona e pili ana i kēia kaʻina hana angiogenesis. Loaʻa pinepine kēia mau meaʻai i ka ʻai Mediterranean. Eia kekahi laʻana:
- Kī ʻōmaʻomaʻo
- ʻAila ʻoliva
- Nā hua waina ʻulaʻula
- Pīnati
- ʻAseparagus
Ke noiʻi nei nā kauka i nā lāʻau lapaʻau hou e hoʻohana ana i kēia mau pūhui kūlohelohe, akā aia nō kēlā noiʻi i kona wā mua.
He mea nui e hoʻomanaʻo i kahi mea nui ma aneʻi. ʻAʻole e ho'ōla ka ʻai ʻana i kēia mau meaʻai i ka maʻi kanesa a i ʻole e hoʻōki i ka ulu ʻana o nā puʻupuʻu kanesa. ʻAʻole loa kēia he pani no nā lāʻau lapaʻau kanesa i kauoha ʻia e ke kauka.
Eia nō naʻe, ʻo ka ʻai ʻana i ka meaʻai momona e hiki ke kōkua nui i ka hoʻomau ʻana i ke kanaka e hele ana i ka lāʻau lapaʻau maʻi kanesa. No laila, e hōʻoia e ʻai i ka meaʻai kaulike.
Leka Lawe-Home
- ʻO nā mea hoʻopale angiogenesis kahi ʻano lāʻau e hoʻōki ai i ke kūkulu ʻia ʻana o nā kīʻaha koko e hoʻolako i ke koko i nā ʻōpū kanesa, e kaohi ana i ko lākou ulu ʻana.
- ʻOiai ʻaʻole hiki i kēia mau mea ke ho'ōla loa i ka maʻi kanesa, hiki iā lākou ke kōkua i ka kaohi ʻana i ka holomua o ka maʻi a hoʻolōʻihi i ke ola.
- Hoʻohana pinepine ʻia kēia mau lāʻau me nā lāʻau ʻē aʻe, e like me ka chemotherapy.
- No ka mea hiki ke loaʻa nā hopena ʻino e like me ke koko kiʻekiʻe a me nā ʻūpā koko, e hoʻomaopopo koke i kāu kauka e pili ana i nā hōʻailona ʻē aʻe e kū mai ana i ka wā o ka mālama ʻana.
- Mai hoʻohana i nā mea hoʻohui meaʻai kūlohelohe ma ke ʻano he pani no ka lāʻau lapaʻau. E hahai mau i ka ʻōlelo aʻo a kāu kauka.
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