Ke hoʻopunipuni nei anei ka ʻōnaehana pale ponoʻī o kou kino iā ʻoe? E aʻo kākou e pili ana i ka Autoimmune Pancreatitis ma ke ala maʻalahi!

He ʻōnaehana pale kupaianaha ko kākou i loko o ko kākou kino, ʻeā? ʻO ia ka mea a kākou e kapa aku nei he ʻōnaehana pale. Mālama ia iā kākou ma ke kaua ʻana i nā germs, bacteria, a me nā virus e hoʻoulu ai i nā maʻi. Akā e noʻonoʻo, pehea inā i kekahi manawa e huikau kēia ʻōnaehana pale ponoʻī o kākou me nā cell maikaʻi i loko o ko kākou kino ponoʻī a hoʻomaka e hoʻouka iā lākou? ʻO ia ka manawa e hana ʻia ai, i kapa ʻia ʻo "Autoimmune Pancreatitis". I ka ʻōlelo maʻalahi, hoʻomaka kāu ʻōnaehana pale ponoʻī e hana kūʻē i kāu pancreas.

He aha ka "Autoimmune Pancreatitis"? I ka pōkole...

E noʻonoʻo i ka ʻōnaehana pale o kou kino e like me kahi pūʻali koa e pale ana i kahi ʻāina. ʻO ka hana a kēia pūʻali koa, ʻo ia ka pale ʻana i ka ʻāina mai nā ʻenemi o waho (e like me nā germs a me nā virus). Akā i loko o ka `(Autoimmune Pancreatitis)`, hana hewa kēia pūʻali koa a hoʻouka i nā kamaʻāina hala ʻole o kona ʻāina ponoʻī (ʻo ia hoʻi, nā cell olakino i loko o ka pancreas) me ka manaʻo he ʻenemi lākou. ʻO ka hopena, lilo ka pancreas i mumū, ʻeha, a ua hoʻopilikia ʻia kāna hana. ʻO kēia ka mea a mākou e kapa nei he autoimmune pancreatitis .

Pehea ka maʻamau o kēia maʻi?

ʻOiaʻiʻo, he maʻi laha ʻole ka `(Autoimmune Pancreatitis)`. Loaʻa pinepine ia i hoʻokahi i loko o hoʻokahi haneli tausani kānaka. Inā mākou e lawe i nā kūlana mumū lōʻihi o ka pancreas (`chronic pancreatitis`), aia wale nō ma kahi o 2% o lākou e hāʻule i loko o kēia māhele `(Autoimmune Pancreatitis)`. No laila, ʻaʻole kēia he maʻi e hoʻopilikia i nā mea āpau.

Aia kekahi mau ʻano o ka `(Autoimmune Pancreatitis)`?

ʻAe, ʻelua mau ʻano nui o ka `(Autoimmune Pancreatitis)`. E nānā kākou i ke ʻano o lākou.

1. ʻAno 1 Autoimmune Pancreatitis

ʻO kēia ke ʻano maʻamau . Ma kēia, loaʻa iā mākou kahi protein i kapa ʻia ʻo `(Immunoglobulin G4)` a i ʻole `(IgG4)` i loko o ko mākou kino. ʻO kēia `(IgG4)` kahi ʻano antibody. Ke pehu a mumū paha ma kekahi wahi o ke kino, piʻi ka pae o kēia `(IgG4)`.

Akā ma kēia ʻano mua, ʻaʻole wale ka pilikia me ka pancreas. Hiki iā ia ke hoʻopilikia i nā ʻāpana ʻē aʻe o ko mākou kino. Eia kekahi laʻana:

• Nā ʻauwai bile: He mau ʻauwai like kēia e like me ka ʻauwai e lawe ana i ka bile mai ke akepaʻa a i ka ʻōpū liʻiliʻi.
• Nā ʻōmole puʻupaʻa: ʻO nā ʻōmole i loko o nā puʻupaʻa.
• Ake
• Nā māmā
• ʻŌpū Gall
• Nā ʻōpū salivary
• ʻO ke kele thyroid

Hiki nō hoʻi ke pehu a me ka hōʻino ʻia ma nā wahi e like me kēia.

2. ʻAno 2 Autoimmune Pancreatitis

Hoʻopilikia wale kēia ʻano i ka pancreas . ʻO ka mea e hana ʻia ma ʻaneʻi, ʻo ia ka hōʻino ʻana o kahi ʻano o ke koko keʻokeʻo i kapa ʻia ʻo "neutrophils" i ka pancreas a me nā ducts pancreatic. ʻIke pinepine ʻia kēia ʻano ma ka poʻe ʻōpio.ʻOi aku ka nui o ko lākou loaʻa ʻana i ka maʻi ʻōpū mumū (IBD).

He aha nā kumu o ka `(Autoimmune Pancreatitis)`? Aia kekahi mau mea pilikia?

Ke hoʻāʻo nei nā kānaka noiʻi e ʻike i ke kumu kikoʻī , akā ʻike pinepine ʻia ia i nā poʻe ma waena o 50 a me 60 mau makahiki. Eia nō naʻe, hiki ke hiki ma mua. ʻOi aku ka pālua o ka loaʻa ʻana o ka maʻi i nā kāne ma mua o nā wahine.

I kekahi manawa, ua manaʻo ʻia he hopena ia o ka ʻōnaehana pale o ke kino i kahi maʻi bacteria. Eia kekahi, ʻoi aku ka nui o ka pilikia o ka poʻe me nā maʻi autoimmune ʻē aʻe i ka loaʻa ʻana. Eia kekahi laʻana:

• (ʻO ka thyroiditis o Hashimoto): ʻO kēia ke kumu e hana iki ai ka ʻōpū thyroid (hypothyroidism).
• (Maʻi ʻōpū mumū - IBD): ʻOi aku hoʻi nā kūlana e like me ka `(ulcerative colitis)`.
• (ʻO ka cholangitis biliary mua)
• ʻO ka fibrosis retroperitoneal: ʻO ke kūkulu ʻia ʻana o nā ʻiʻo e like me ka ʻōpala ma ka ʻaoʻao o ke kua o ka ʻōpū.
• ʻO ka rumatika: Ka mumū o nā hono.
• (ʻO ka maʻi sarcoidosis)
• (ʻO ka maʻi Sjögren)

Inā loaʻa iā ʻoe nā maʻi autoimmune ʻē aʻe e like me kēia, he mea maikaʻi e hopohopo iki e pili ana i ka Autoimmune Pancreatitis pū kekahi.

He aha nā hōʻailona o ka `(Autoimmune Pancreatitis)`?

I nā pae mua o kēia maʻi , ʻaʻohe paha he mau hōʻailona . Eia nō naʻe, i ka holomua ʻana o ka maʻi, hoʻomaka nā ala pancreatic e haiki, e pale ana i nā enzymes i hūnā ʻia e ka pancreas mai ka hiki ke hele pono.

ʻO ka paʻa ʻana o ka ʻōpū pancreatic e hiki ke hana i nā hōʻailona e like me:

• ʻEha ʻōpū o luna
• ʻEha kua waena
• Ka maʻi pākī
• Ka luaʻi/ka luaʻi ʻana
• Ka emi ʻana o ke kaumaha

He mea nui: Hiki ke ʻike ʻia kekahi o kēia mau hōʻailona i ka maʻi kanesa pancreatic. No laila, inā loaʻa iā ʻoe kēia mau hōʻailona, ​​​​he mea naʻauao ke ʻole e hopohopo a ʻike koke i ke kauka e ʻike pono i ke kumu o ka pilikia . ʻO ka loaʻa ʻana o ka `(Autoimmune Pancreatitis)` ʻaʻole ia he manaʻo he maʻi kanesa kou.

Eia kekahi, hiki i ka pancreatitis autoimmune ke hoʻoulu i ka pehu ʻana, nā ulu ʻana ʻaʻole maʻi kanesa, a me nā cysts piha i ka wai i loko o ka pancreas. Inā loaʻa kēia mau pehu, puʻupuʻu, a i ʻole cysts i loko o ke poʻo o kou pancreas, hiki iā lākou ke ālai i ke ala bile, hiki ke pale i ka bile mai ke kahe pono ʻana i loko o ka ʻōpū liʻiliʻi. Loaʻa i ka Bile kahi pigment i kapa ʻia ʻo bilirubin. Ke hōʻiliʻili kēia bilirubin i loko o ke koko, hiki iā ia ke hana i ka jaundice.Lilo ka ʻili a me ke keʻokeʻo o nā maka i melemele (jaundice), a luhi paha ʻoe. Ke piʻi ka bilirubin i loko o ka mimi , lilo ka mimi i ʻeleʻele . Ke hoʻokuʻu ʻia ka bilirubin i loko o nā ʻōpū , lilo paha nā ʻōpala i kala melemele .

He aha nā pilikia e hiki mai ana o ka `(Autoimmune Pancreatitis)`?

Hiki i ka mumū mau o ka pancreas ke hoʻoulu i ka nausea, ka pohō kaumaha, a me ka ʻeha mau ma ka ʻōpū o luna a me ke kua. Eia kekahi, inā ua hōʻino ʻia nā hunaola e hana ana i ka insulin i loko o ka pancreas , hiki ke ulu ka maʻi diabetes .

Hiki i nā antibodies IgG4 ke hoʻouka ʻaʻole wale i ka pancreas, akā i nā ʻōpū ʻē aʻe, ʻoi aku hoʻi i ka Type 1. ʻO ia mau ʻōpū:

• Nā ʻauwai bile
• Nā ʻōpū salivary
• Nā kelepa waimaka
• ʻO ke kelepaʻi thyroid (ʻO ka thyroid)
• nā puʻupaʻa
• Puʻuwai
• Nā māmā a me ka pleura (ka uhi o nā māmā)

Pehea e ʻike ʻia ai ka pancreatitis autoimmune?

I mea e ʻike pololei ai i kēia maʻi a e hōʻoia ʻaʻole ia he maʻi ʻaʻai pancreatic, pono kekahi mau hoʻokolohua. Pono ʻoe e loaʻa nā hoʻokolohua e like me kēia:

• Nā hoʻāʻo koko: Nānā kēia i nā pae kiʻekiʻe o IgG4, a me ka hana o ke akepaʻa a me nā pae o kekahi mau ʻano cell koko.
• Nā hoʻāʻo kiʻi: Nānā kēia i ka nui o ka pancreas, inā he mau ʻeha, a inā paha ua ʻūmiʻi nā ducts. ʻO nā hiʻohiʻona o kēia mau hoʻāʻo ʻo `(CT scan)` a me `(MRI scan)`.
• Biopsy: Pili kēia i ka lawe ʻana i kahi ʻāpana liʻiliʻi o ka ʻiʻo mai kou pancreas a nānā iā ia ma lalo o kahi microscope. Hana pinepine ʻia kēia ma o kahi kaʻina hana endoscopic minimally invasive i kapa ʻia ʻo Endoscopic Ultrasound (EUS). Ma kēia kaʻina hana, hoʻokomo kāu kauka i kahi paipu lōʻihi a palupalu (me kahi kukui a me kahi mea ultrasound ma kekahi ʻaoʻao) i loko o kou ʻōpū a me nā ʻōpū e nānā i kāu pancreas. A laila lawe ʻia kahi laʻana biopsy ma o kou ʻōpū a i ʻole nā ​​​​ʻōpū. I kekahi manawa, pono paha ke kauka lapaʻau e hana i kahi ʻoki liʻiliʻi i kou ʻili (laparoscopy) e lawe i kahi laʻana biopsy.
• Hoʻāʻo Corticosteroid: Kōkua pū kēia i ka hōʻoia ʻana i ka hōʻailona. Hāʻawi ʻia ʻoe i nā steroids no kahi manawa pōkole e ʻike ai inā e emi ana kāu mau pae IgG4 a hoʻomaikaʻi kāu mau hoʻokolohua kiʻi.

Pehea e mālama ʻia ai ka `(Autoimmune Pancreatitis)`?

ʻO ka mea kupanaha, no kahi poʻe liʻiliʻi loa, hoʻopau kēia maʻi iā ia iho me ka ʻole o ka lāʻau lapaʻau . Akā no ka poʻe he nui, pono ka lāʻau lapaʻau .

Hoʻomaʻamaʻa pinepine ʻia ka Autoimmune pancreatitis me nā corticosteroids.He ʻano lāʻau lapaʻau i kapa ʻia he steroid. Eia kekahi laʻana, he lāʻau lapaʻau e like me `(prednisone)` a i ʻole `(prednisolone)`. Hana kēia mau lāʻau lapaʻau ma ka hōʻemi ʻana i ka pehu a me ka hōʻoluʻolu ʻana i kahi ʻōnaehana pale ikaika loa. Hoʻomaka ka lāʻau lapaʻau me kahi mahele nui o nā steroid. A laila hoʻemi mālie ʻia ka mahele (`tapered`).

Inā ʻaʻohe ou pilikia, ʻaʻole pono ʻoe i kekahi lāʻau lapaʻau hou aʻe. Aia ka lāʻau lapaʻau e pono ai ma ke ʻano o ka pilikia. Inā he ʻūmiʻi o ke ala pancreatic ('duct narrowing'), hiki ke hana ʻia kahi hana e wehe i ke ala a hoʻoikaika iā ia me kahi mea hollow mesh ('stent').

Hiki iaʻu ke pale aku i ka loaʻa ʻana o ka `(Autoimmune Pancreatitis)`?

ʻOiaʻiʻo, ʻaʻohe mea hiki iā ʻoe ke hana e pale aku i kēia maʻi mai ka ulu ʻana no ka mea he pilikia ia me kā mākou ʻōnaehana pale ponoʻī.

He aha ka manaʻo no ka poʻe me ka `(Autoimmune Pancreatitis)`?

Hoʻōla maikaʻi ka hapa nui o ka poʻe ma hope o ka mālama ʻana i ka corticosteroid , a ʻaʻohe pilikia. ʻAʻole pili ka loaʻa ʻana o ka pancreatitis autoimmune i kou manaʻolana ola .

Eia nō naʻe, hiki i ka `(Autoimmune Pancreatitis)` ke hoʻi hou (relapse) . He mea maʻamau kēia i nā poʻe me ke ʻano mua (`Type 1`). ʻOi aku ka nui o ka maʻi e hoʻi hou i loko o nā makahiki ʻekolu mua ma hope o ka ʻike ʻia ʻana. ʻOi aku ka nui o ka loaʻa ʻana o nā pilikia i ka mea i loaʻa i ka maʻi.

He aha ka mea e hana ʻia inā hoʻi hou mai ka maʻi?

Inā mālama pono ʻia, hiki i ka poʻe me ka maʻi e hoʻi hou ana ke ola i nā ola hana a olakino .

Pono paha ʻoe e hoʻomaka hou i ka hoʻohana ʻana i nā corticosteroids. Hoʻomau kekahi poʻe i ka mālama ʻana i ka steroid no kekahi mau makahiki e pale ai i nā hōʻailona mai ka hoʻi hou ʻana mai. Hiki i nā kauka ke hoʻāʻo i nā lāʻau lapaʻau ʻē aʻe e mālama ai i kahi ʻōnaehana pale overactive (nā lāʻau immunomodulatory a me nā immunosuppressive).

Pehea koʻu manaʻo i ka wā o ka mālama ʻana?

Hiki ke loaʻa kekahi mau hopena ʻaoʻao i ka wā e hoʻohana ai i nā steroids. No ka laʻana, ka ʻōpū ʻeha, ka makemake nui, ka hoʻomaha ʻole, a me ka paʻakikī o ka hiamoe. Hiki i kēia mau hopena ʻaoʻao ke hoʻopilikia iki i ke ola o kēlā me kēia lā, akā he manawa pōkole wale nō . No ka loaʻa ʻana o ka mea nui loa mai kāu lāʻau Autoimmune Pancreatitis, he mea nui e hoʻomau i ka lawe ʻana i nā steroids e like me ke kauoha a kāu kauka .

Inā pilikia loa nā hopena ʻaoʻao e hoʻomanawanui, e hōʻoia e hoʻomaopopo i kāu kauka ma mua o ka hoʻōki ʻana i ka lāʻau. Hiki iā ia ke kuhikuhi i nā lāʻau lapaʻau hou e kōkua iā ʻoe e loaʻa ka hōʻoluʻolu, a i ʻole e hoʻololi i kāu hoʻolālā lapaʻau.

Āhea e hiki ai iaʻu ke hoʻi i nā hana maʻamau ma hope o ka mālama ʻana no ka `(Autoimmune Pancreatitis)`?

ʻO ka maʻamau, hāʻawi ka lāʻau steroid i ka hōʻoluʻolu mai nā hōʻailona o ka '(Autoimmune Pancreatitis)' i loko o kekahi mau pule.Hoʻi ka nui o ka poʻe i kā lākou hana maʻamau ma hope o ka pau ʻana o kā lākou mau hōʻailona.

He maʻi mumū kakaikahi ka Autoimmune Pancreatitis e hiki ke hoʻopilikia i ka hana o ka pancreas. ʻO ka ʻike ʻana i kahi kauka i kamaʻāina i nā maʻi pancreatic hiki ke kōkua iā ʻoe e loaʻa ka mālama maikaʻi loa āu e pono ai. Hoʻōla piha ka hapa nui o ka poʻe ma hope o ka lawe ʻana i nā steroids . Pono paha kekahi poʻe i nā lāʻau lapaʻau Autoimmune Pancreatitis hou e hoʻokō ai i ka hōʻoluʻolu lōʻihi.

ʻO ka mea hope loa, e hoʻomanaʻo i kēia (Leka Lawe-Home)

• ʻO ka Autoimmune Pancreatitis kahi maʻi kakaikahi kahi e hoʻouka ai kāu ʻōnaehana ponoʻī i kāu pancreas.
• Inā loaʻa iā ʻoe nā hōʻailona e like me ka ʻeha o ka ʻōpū, ka pohō kaumaha, a i ʻole ka jaundice , e ʻimi pono i ke kōkua lapaʻau .
• ʻAʻole kēia he maʻi ʻaʻai pancreatic, akā ua like nā hōʻailona, ​​​​no laila he mea nui ka ʻike pololei .
• ʻO ka lāʻau lapaʻau nui he corticosteroids.
• Hoʻōla maikaʻi nā kānaka he nui me ka lāʻau lapaʻau, akā hiki i ka maʻi ke hoʻi hou mai.
• He mea nui loa e hahai pololei i nā ʻōlelo a ke kauka no ka ho'ōla koke ʻana .

E hoʻomanaʻo, ʻaʻole ʻoe hoʻokahi. He mea maʻamau ka nui o nā manaʻo e holo ana i loko o kou noʻonoʻo i kahi kūlana e like me kēia. No laila, e wehe i kāu kauka a nīnau i kāu mau nīnau. Eia lākou e kōkua iā ʻoe.

ʻO ka Pancreatitis Autoimmune, Pancreatitis, Autoimmunity, IgG4, Ola kino o ka pancreas, Pancreatitis Sinhala, Ola kino ʻōpū