Ke haʻi aku kāu kauka iā ʻoe he maʻi diabetes kou, ʻo ka mea mua paha e kuhikuhi ʻia iā ʻoe he pila i kapa ʻia ʻo Metformin. I kēia lā, e kamaʻilio maʻalahi a maopopo mākou e pili ana i kēia lāʻau maʻamau i kuhikuhi ʻia i nā poʻe he nui no ka maʻi Diabetes Type 2, ʻaʻole wale ma Sri Lanka, akā a puni ka honua. E nānā mākou i nā mea āpau mai kona ʻano, kāna hana i ke kino, a me nā mea e pono ai mākou e makaʻala.
He aha nā biguanides? Ua like anei ia me ka metformin?
I ka ʻōlelo maʻalahi, ʻo Biguanides ka inoa i hāʻawi ʻia i kahi hui o nā lāʻau lapaʻau i hoʻohana ʻia e mālama i ka maʻi diabetes. E like me nā ʻano kaʻa. E like me nā ʻano kaʻa, nā van, a me nā kaʻa, aia nā hui like ʻole o nā lāʻau lapaʻau maʻi diabetes. ʻO Biguanides kekahi o ia mau hui.
I kēia manawa, ʻo Metformin wale nō ka lāʻau lapaʻau i hoʻohana ʻia ma kēia māhele ma ka hapa nui o nā ʻāina o ka honua. ʻO ia hoʻi, inā ʻoe e lawe iā Metformin, ke lawe nei ʻoe i kahi lāʻau lapaʻau no ka papa Biguanide. He lāʻau lapaʻau kēia i lawe ʻia ma ka waha ma ke ʻano he papa. Hiki ke loaʻa kēia lāʻau lapaʻau ma lalo o nā inoa inoa like ʻole e like me Glucophage®, Fortamet®, akā aia ka Metformin iā lākou āpau.
He aha nā kūlana e hoʻohana ʻia ai ʻo Metformin?
ʻO ka hoʻohana nui a i ʻae ʻia e ka metformin, ʻo ia ke kāohi ʻana i ka maʻi diabetes type 2. ʻO ka ʻoiaʻiʻo, ʻo ka metformin ka lāʻau lapaʻau mua a nā kauka e hoʻomaka ai no ka maʻi diabetes type 2.
Akā eia kekahi, ua kuhikuhi pū nā kauka i kēia lāʻau no kekahi mau kūlana olakino ʻē aʻe. Ua kapa ʻia kēia he "off-label" use. ʻO ia hoʻi, ua hāʻawi ʻia ka lāʻau no nā hoʻohana pono ʻē aʻe ma mua o nā mea i ʻāpono mua ʻia ai.
| Nā hoʻohana ʻē aʻe o Metformin | He wehewehe maʻalahi |
|---|---|
| Maʻi diabetes hāpai | E kāohi i ka maʻi diabetes e kū mai ana i kekahi mau makuahine i ka wā hāpai. |
| Prediabetes | E kāohi i nā pae kō koko i loko o ka poʻe i pilikia i ka loaʻa ʻana o ka maʻi diabetes a hoʻopaneʻe a pale paha i ka ulu ʻana o ka maʻi diabetes. |
| ʻO ka maʻi ovary polycystic (PCOS) | Kōkua i ka hoʻoponopono ʻana i nā hormonal imbalances a me nā menstrual cycles i nā wahine me PCOS. |
| ʻO kekahi mau lāʻau lapaʻau psychiatric e hoʻonui ai i ke kaumaha | E kāohi i ka piʻi ʻana o ke kaumaha i hoʻokumu ʻia e nā lāʻau lapaʻau no kekahi mau maʻi noʻonoʻo. |
Eia kekahi, ua ʻike kekahi mau noiʻi e hiki i ka poʻe e lawe ana i ka metformin ke emi iho ka pilikia o ka hoʻomohala ʻana i ka maʻi kanesa, akā aia nō kēia ma ke kahua noiʻi.
Pehea ka hana ʻana o kēia lāʻau Metformin i loko o ke kino?
Kōkua ʻo Metformin i ke kāohi ʻana i nā pae kō o ko mākou kino ma nā ʻano nui ʻelua.
1. Hoʻemi i ka nui o ke kō i hoʻohui ʻia i ke koko e ke akepaʻa: ʻO ka maʻamau, hoʻokuʻu ko mākou akepaʻa i ke kō (glucose) i loko o ke koko no ka ikehu. Hoʻomalu ʻo Metformin i kēia kaʻina hana a hoʻemi i ka hōʻiliʻili pono ʻole o ke kō i loko o ke koko.
2. Hoʻonui i ka ʻike o ka insulin i loko o nā ʻiʻo: ʻO kekahi o nā hana nui o ka hormone insulin i loko o ko mākou kino, ʻo ia ke kōkua i nā ʻāpana e lawe i ke kō mai ke koko a hoʻohana iā ia no ka ikehu. I ka maʻi diabetes, ua hoʻopilikia ʻia kēia kaʻina hana. Hoʻomaikaʻi ʻo Metformin i ko mākou mau ʻiʻo i ka pane ʻana i ka insulin. A laila, hiki i nā ʻiʻo ke omo maʻalahi a hoʻohana i ke kō i loko o ke koko.
Kōkua kēia mau ʻano hana ʻelua i ka kaohi ʻana i nā pae kō koko kiʻekiʻe. I ka PCOS, hoʻohaʻahaʻa kēia lāʻau lapaʻau i nā pae insulin, kahi e kōkua ai i ke kaulike ʻana i nā hormones a hoʻoponopono i ke kaʻina hana menstrual.
He aha nā pono nui o Metformin?
- Ka kaohi maikaʻi ʻana i ka maʻi diabetes: Ua hōʻike ʻia nā noiʻi hiki i ka metformin ke hōʻemi i kāu waiwai hoʻāʻo HbA1c, e hōʻike ana i kou awelika o ke kō koko i nā mahina ʻekolu i hala, ma kahi o 1% .
- Ke pale ʻana i ka maʻi diabetes: Ua ʻike ʻia ʻo ka lawe ʻana i ka Metformin me nā hoʻololi ʻana i ke ʻano o ka nohona hiki ke hōʻemi i ka pilikia o ka hoʻomohala ʻana i ka maʻi diabetes ma kahi o 31% i nā poʻe me ka prediabetes.
- Hoʻemi ʻia ka pilikia o ka maʻi puʻuwai: Manaʻo kekahi mau noiʻi e hōʻemi paha ka metformin i ka pilikia o ka maʻi puʻuwai a me nā pilikia e pili ana (maʻi cardiovascular).
Aia kekahi mau hopena ʻaoʻao i kēia lāʻau lapaʻau?
ʻAe, e like me nā lāʻau lapaʻau āpau, hiki i ka Metformin ke hana i kekahi mau hopena ʻaoʻao. Eia nō naʻe, no ka hapa nui o ka poʻe, hiki wale kēia mau mea ke hoʻomaka mua lākou e lawe i ka lāʻau lapaʻau a laila nalowale ke hoʻomaʻamaʻa ke kino iā ia.
| Ka hopena ʻaoʻao | E aʻo e pili ana i kēia |
|---|---|
| Nā hopena ʻaoʻao maʻamau e ʻike ai ka poʻe he nui | |
| ʻAʻai ʻole, diarrhea | ʻO kēia ka hopena ʻaoʻao maʻamau. Nalo pinepine ia i loko o kekahi mau lā. Hiki iā ʻoe ke hōʻemi i kēia ma ka lawe ʻana i ka lāʻau me ka meaʻai. |
| Ka luaʻi a me ka luaʻi | He mea maʻamau nō hoʻi kēia i nā wā mua. |
| Nā hopena ʻaoʻao kakaikahi | |
| ʻO ka ʻeha o ka umauma, ka ʻeha poʻo, ka hou nui ʻana (diaphoresis), a me ka manaʻo palaualelo. | ʻAʻole kēia mau mea maʻamau, akā inā hoʻomau ʻoe i kēia mau hōʻailona, e haʻi i kāu kauka. |
| Ke kō koko haʻahaʻa (Hypoglycemia) | ʻAʻole paha e hiki mai kēia inā ʻoe e lawe i ka metformin wale nō, akā hiki ke hana ʻia ke lawe pū ʻoe me nā lāʻau lapaʻau maʻi diabetes ʻē aʻe. |
He aha nā pilikia kūikawā e pono ai ke makaʻala me ka metformin?
He lāʻau palekana loa ka Metformin ma ke ʻano laulā. Eia nō naʻe, aia kekahi mau pilikia kikoʻī e pono ai kākou āpau e makaʻala.
Ka nele o ka wikamina B12
ʻO Metformin no ka manawa lōʻihiKe hoʻohana ʻia, hiki ke hoʻemi iki ʻia ka omo ʻana o ke kino i ka wikamina B12. No laila, e nānā paha kāu kauka i kāu mau pae wikamina B12 a, inā pono, e kuhikuhi i kahi mea hoʻohui wikamina B12.
ʻAkika Lactic
ʻO kēia ka mea nui loa e pono ai i nā mea a pau ke makaʻala i ke kamaʻilio ʻana e pili ana i ka Metformin. Akā ʻo ka mea mua, pono e ʻōlelo ʻia he mea laha ʻole kēia, akā he kūlana koʻikoʻi hiki ke hoʻoweliweli i ke ola inā loaʻa. Ma kahi o hoʻokahi i loko o 30,000 mau kānaka e lawe ana i ka Metformin he pilikia kēia.
- He aha ka Lactic Acidosis? I ka ʻōlelo maʻalahi, ʻo ia ka hōʻiliʻili pono ʻole ʻana o kahi kemika i kapa ʻia ʻo ka lactic acid i loko o ke kino.
- ʻO wai ka mea i ʻoi aku ka pilikia no kēia?
- No ka poʻe me nā maʻi puʻupaʻa a i ʻole ke akepaʻa.
- No nā poʻe ma luna o 65 mau makahiki.
- No ka poʻe i hana ʻia i ke ʻoki kino i hala koke aku nei.
- No ka poʻe e inu nui ana i ka waiʻona.
- Nā hōʻailona o ka lactic acidosis:
- Luhi nui a me ka nāwaliwali koke.
- Ka luaʻi, ka luaʻi ʻana, a me ka ʻeha o ka ʻōpū.
- Hanu wikiwiki a hanu hohonu a lōʻihi paha.
ʻŌlelo Aʻo: Inā ʻoe e lawe ana i ka Metformin a ʻike i kekahi a ʻoi aku paha o kēia mau hōʻailona, e hele koke i ka keʻena pilikia o ka haukapila kokoke loa (ETU). ʻAʻole kēia he mea e hoʻopaneʻe ai.
Nā Hana like ʻana o nā Lāʻau Lapaʻau
Inā ʻoe e lawe ana i ka Metformin, he mea nui loa ia e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau ʻē aʻe āu e lawe nei (me nā lāʻau lapaʻau no nā kūlana ʻē aʻe, nā huaora, a me nā mea hoʻohui meaʻai). Hiki i kekahi mau lāʻau lapaʻau ke hoʻonui i ka pilikia o ka lactic acidosis a i ʻole ke kō koko haʻahaʻa (hypoglycemia) ke lawe pū ʻia me Metformin.
Āhea wau e kamaʻilio ai me ke kauka?
Inā ʻoe e lawe ana i ka Metformin, he mea nui e ʻike pinepine i kāu kauka e hōʻoia i ka hana ʻana o ka lāʻau lapaʻau a ua kaohi ʻia kou kō koko. Eia kekahi, e kamaʻilio pū me kāu kauka e pili ana i kēia mau mea.
- Inā nui loa nā hopena ʻaoʻao no ʻoe e lawelawe.
- Inā manaʻo ʻoe ʻaʻole e kaohi pono ʻia kou mau maʻi e like me ka maʻi diabetes a i ʻole PCOS me ka lawe ʻana i ka lāʻau lapaʻau.
- Inā manaʻo ʻoe e pono ʻoe e hoʻōki i ka lawe ʻana i kēia lāʻau lapaʻau ( mai hoʻōki i ka lawe ʻana i ka lāʻau lapaʻau me ka ʻole o ke nīnau ʻana i kāu kauka ).
Leka Lawe-Home
- He lāʻau lapaʻau maʻamau, palekana, a maikaʻi hoʻi ka Metformin no ka maʻi diabetes type 2.
- Hana nui kēia ma ka hoʻemi ʻana i ka hana kō e ke akepaʻa a me ka hoʻonui ʻana i ka ʻike o ka insulin i loko o nā ʻiʻo.
- ʻO nā hopena ʻaoʻao maʻamau, e like me ka pehu ʻana, hiki ke loaʻa mua a laila nalo i ka wā e hoʻololi ai ke kino.
- He maʻi laha ʻole akā he maʻi koʻikoʻi ka Lactic Acidosis. E makaʻala i kona mau hōʻailona a e hele koke i ka ETU inā ʻike ʻoe i kekahi o kēia mau hōʻailona.
- He mea nui e hoʻomaopopo i kāu kauka e pili ana i nā lāʻau lapaʻau ʻē aʻe āu e lawe nei.
- Mai ho'ōki i ka lawe ʻana i ka Metformin me ke aʻo ʻole ʻia e ke kauka. Inā he mau nīnau kāu, mai kānalua e nīnau i kāu kauka.
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