Ke nānā ʻoe i kahi hoʻāʻo koko, nui paha kou nānā ʻana i ka cholesterol, ʻoiai ka cholesterol maikaʻi ʻole, ʻo LDL. No ka mea, ua ʻike mākou a pau i ka piʻi ʻana o nā pae LDL, piʻi ka manawa kūpono e loaʻa ai nā maʻi e like me nā hōʻeha puʻuwai a me nā hahau. Akā, ʻaʻole i pau ka moʻolelo ma laila. Ua ʻike ʻia nā noiʻi he 50% o ka poʻe i loaʻa i nā hōʻeha puʻuwai ʻaʻole i loaʻa nā pae LDL kiʻekiʻe. No laila, hoʻohana nā kauka i kahi hoʻāʻo ʻē aʻe e loiloi pololei i ka pilikia. ʻO ia ka mea a mākou e kapa nei ʻo ka hoʻāʻo C-Reactive Protein, a i ʻole CRP.
He aha maoli ka CRP?
I ka ʻōlelo maʻalahi, ʻo ka C-Reactive Protein (CRP) kahi protein i hana ʻia e ko kākou ake. Ke loaʻa ka mumū , ʻo ia hoʻi, ka pehu ʻana i hana ʻia e kekahi pōʻino, ma kekahi wahi o kou kino, piʻi aʻe kēia pae CRP i loko o ke koko.
E noʻonoʻo i kēia ʻano. ʻAʻole wale ka cholesterol maikaʻi ʻole (LDL) e pipili i nā paia o ko kākou mau kīʻaha koko, hōʻino pū kekahi iā lākou. ʻO kēia pōʻino ka mea a mākou e kapa nei he mumū. Ua like ia me kahi ʻeha liʻiliʻi. Ke hoʻāʻo ke kino e ho'ōla i kēia pōʻino, hana ia i nā protein kūikawā e hana ma ke ʻano he "hui kōkua." ʻO CRP kekahi o ia mau protein. ʻO ia hoʻi, inā he mumū ma kekahi wahi o ke kino, hiki iā mākou ke ʻike iā ia mai ka pae CRP. Ua like ia me ka wā e ʻike ai mākou i ka uahi, manaʻo mākou he ahi ma kekahi wahi.
No ke aha e ʻōlelo ai ke kauka i kahi hoʻokolohua CRP?
Ana ka hoʻāʻo CRP i ka nui o ka C-Reactive Protein i loko o kou koko. Hiki i kēia ke hāʻawi i kāu kauka i kahi manaʻo maikaʻi o ke kiʻekiʻe o ka mumū i loko o kou kino.
Manaʻo kekahi mau noiʻi he ʻoi aku ka maikaʻi o ka CRP i ka wānana ʻana i ka pilikia o ka maʻi cardiovascular (CVD) ma mua o ka LDL cholesterol. Eia naʻe, ʻaʻole ia he hoʻāʻo kikoʻī no ka maʻi puʻuwai. Hōʻike wale ia inā he mumū i loko o ke kino. Hiki ke hana ʻia ka mumū e ka maʻi puʻuwai a i ʻole kekahi mea ʻē aʻe.
Aia kekahi mau hihia ʻē aʻe kahi e hoʻohana ʻia ai kēia hoʻāʻo:
- Nā Maʻi Autoimmune: Hana ʻia kēia hoʻāʻo no ka poʻe me nā maʻi e like me Lupus a i ʻole Rheumatoid Arthritis. No ka mea, hoʻoulu kēia mau maʻi i ka mumū i loko o ke kino. Kōkua pū kēia hoʻāʻo e ʻike inā hōʻemi ka lāʻau i hāʻawi ʻia i kēlā mumū. Eia naʻe, ʻaʻole hiki i kēia hoʻāʻo ke haʻi i kahi o ke kino o ka mumū.
- Nā maʻi: Hana ʻia kēia hoʻāʻo inā he kānalua no kahi maʻi ʻōnaehana e like me ka sepsis, ka maʻi fungal, a i ʻole ka maʻi iwi.
- Ka pilikia o ka lua o ka hōʻeha puʻuwai: Hoʻohana ʻia hoʻi e ʻike i ka pilikia o ka loaʻa ʻana o kahi hōʻeha puʻuwai ʻē aʻe no kekahi mea i loaʻa mua i ka hōʻeha puʻuwai.
- Nā maʻi ʻē aʻe:Kōkua pū kēia i ka ʻike ʻana i nā kūlana e like me ka maʻi ʻōpū mumū a me ka maʻi māmā.
Pehea e hoʻomaopopo ai i nā waiwai i ka hōʻike CRP?
Hiki i kāu kauka ke kauoha i kēia hoʻāʻo CRP inā loaʻa iā ʻoe nā hōʻailona o kahi maʻi, e like me ke kuni, nā anu, ka wikiwiki o ka puʻuwai, ka piʻi ʻana o ka hanu ʻana, ka nausea, a me ka luaʻi.
He hoʻāʻo koko maʻalahi loa kēia. ʻO ka maʻamau, lawe ʻia kahi koko liʻiliʻi mai kahi aʻa koko ma kou lima. ʻAʻole pono ia i kekahi hoʻomākaukau kūikawā (e like me ka hoʻokē ʻai). ʻAʻohe ʻeha ʻē aʻe ma mua o kahi wahi ʻeha liʻiliʻi kahi i hoʻokomo ʻia ai ke kui. Eia nō naʻe, hiki i kekahi mau lāʻau lapaʻau āu e lawe nei ke hoʻopilikia i nā hopena o kēia hoʻāʻo. No laila e hōʻoia e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei.
Ke loaʻa iā ʻoe kāu mau hopena, e kōkua ka papa ma lalo nei iā ʻoe e hoʻomaopopo i nā waiwai. Akā e hoʻomanaʻo, hiki ke ʻokoʻa iki kēia mau waiwai mai ka hale hana a i ka hale hana. No laila e hōʻike pono i kāu hōʻike i kāu kauka a loaʻa ka ʻōlelo aʻoaʻo.
| Pae mumū | Ka waiwai CRP (mg/dL) | Manaʻo/kumu kūpono |
|---|---|---|
| Kiʻekiʻe Waena | 1.0 - 10.0 mg/dL | Nā maʻi Autoimmune e like me ka rheumatoid arthritis, lupus, ka hōʻeha puʻuwai, pancreatitis, bronchitis. |
| Kiʻekiʻe i hōʻailona ʻia | 10.0 - 50.0 mg/dL | Nā maʻi bacteria a viral paha, ka mumū o nā kīʻaha koko (Systemic Vasculitis), kahi ulia pōpilikia koʻikoʻi a i ʻole ka ʻeha. |
| Kiʻekiʻe koʻikoʻi | ʻOi aku ma mua o 50.0 mg/dL | ʻO ka hapa pinepine (90%) ua hoʻoulu ʻia e kahi maʻi bacteria koʻikoʻi. Hiki i nā kūlana e like me ka dengue, malaria, a me ka hepatitis C ke hana pū. |
ʻO ka pae CRP ma luna o 10 mg/dL i manaʻo ʻia he hōʻailona ia o ka mumū nui. Eia naʻe, ʻaʻole hiki i kēia hoʻāʻo wale nō ke haʻi i ke kumu. Pono kāu kauka e hana i nā hoʻokolohua hou aʻe e hoʻoholo ai i ke kumu.
He hoʻāʻo CRP kūikawā (hs-CRP) e nānā ana i ka pilikia o ka maʻi puʻuwai
Aia kekahi hoʻāʻo i ʻoi aku ka maʻalahi ma mua o ka hoʻāʻo CRP maʻamau, i hoʻohana ʻia e loiloi i ka pilikia o ka maʻi cardiovascular (CVD). Ua kapa ʻia ʻo High-Sensitivity CRP (hs-CRP) .
ʻOi aku ka pono o kēia hoʻāʻo no ka poʻe i loaʻa ka pilikia o 10%-20% o ka loaʻa ʻana o ka hōʻeha puʻuwai i loko o nā makahiki he 10 e hiki mai ana. Hiki i nā pae CRP, e like me nā pae cholesterol, ke kōkua i ka wānana ʻana i ka pilikia o ka maʻi puʻuwai. Ua ʻike ʻia kekahi noiʻi ua hoʻonui ʻia ka pilikia o ka loaʻa ʻana o nā pae CRP kiʻekiʻe i ʻekolu manawa.
Eia ke ʻano o ka wehewehe ʻana i nā hopena hs-CRP:
| ka waiwai hs-CRP (mg/L) | Ka pilikia o ka maʻi cardiovascular (CVD) |
|---|---|
| Ma lalo o 1.0 mg/L | Ka pilikia haʻahaʻa |
| 1.0 mg/L a i 3.0 mg/L | Ka pilikia kūpono |
| ʻOi aku ma mua o 3.0 mg/L | Kiʻekiʻe ka pilikia |
No ka mea hiki ke ʻokoʻa iki nā pae CRP i kēlā me kēia lā, ʻoi aku ka maikaʻi o ka hana ʻana i kēia hoʻāʻo ʻelua, ʻelua pule ka mamao, e loiloi pololei i kou pilikia o ka maʻi puʻuwai. Eia kekahi, ʻo ka loaʻa ʻana o kahi pae hs-CRP kiʻekiʻe ʻaʻole ia he manaʻo he maʻi puʻuwai kou. No laila he mea nui e hoʻohālikelike iā ia me kāu pae cholesterol LDL e loaʻa ai ke kiʻi piha.
He aha kāu e hana ai inā kiʻekiʻe kāu pae CRP?
Inā kiʻekiʻe kou pae CRP, e hilinaʻi ka lāʻau lapaʻau i ke kumu. Inā kiʻekiʻe kou pae CRP ma muli o kahi kumu pilikia no ka maʻi puʻuwai, aia kekahi mau mea hiki iā ʻoe ke hana e hōʻemi i kēlā pilikia:
- E ʻai i ka meaʻai olakino no ka puʻuwai: E ʻai i nā meaʻai haʻahaʻa i ka ʻaila, ka paʻakai, a me ke kō, a kiʻekiʻe i nā huaʻai a me nā mea kanu.
- E kāohi i ka cholesterol.
- E mālama i ke kaumaha o ke kino kūpono.
- E hoʻoikaika kino i nā manawa a pau.
- Inā loaʻa iā ʻoe ka maʻi diabetes a i ʻole ke koko kiʻekiʻe, e kaohi pono iā lākou.
- Inā ʻoe e puhipaka ana, e hoʻōki koke.
- E kaupalena i ka inu ʻana i ka waiʻona.
ʻO Statins, kahi ʻano lāʻau hoʻohaʻahaʻa cholesterol, hiki ke kōkua i ka hōʻemi ʻana i ka pilikia o ka maʻi puʻuwai i nā poʻe me nā pae CRP kiʻekiʻe. Eia nō naʻe, inā maʻamau kāu mau pae cholesterol, ʻaʻole paha ʻo statins ka pane kūpono no nā pae CRP kiʻekiʻe. ʻOi aku ka maikaʻi o ke kamaʻilio ʻana me kāu kauka e pili ana i ke koho lapaʻau kūpono loa iā ʻoe.
Leka Lawe-Home
- ʻO ka hoʻāʻo CRP ke ana i ka mumū i loko o ke kino, ʻaʻole i kahi maʻi kikoʻī.
- He mea pono loa kēia no ka loiloi ʻana i nā kūlana e like me ka pilikia o ka maʻi puʻuwai, nā maʻi, a me nā maʻi autoimmune.
- Inā kiʻekiʻe kāu pae CRP, pono paha i kāu kauka ke hana i nā hoʻokolohua hou aʻe e ʻike ai i ke kumu.
- Hoʻohana ʻia kahi hoʻokolohua ʻoi aku ka naʻauao i kapa ʻia ʻo hs-CRP e loiloi pono i ka pilikia o ka maʻi puʻuwai.
- He mea nui nā loli o ke ʻano o ka nohona no ka mālama ʻana i nā kiʻekiʻe CRP kiʻekiʻe, akā e ʻoluʻolu e nīnau i kāu kauka no kekahi lāʻau lapaʻau.
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