Loaʻa iā ʻoe kēia mau hōʻailona? E kamaʻilio kākou e pili ana i ka Cushing Syndrome!

Ua lohe paha ʻoe i ka Cushing Syndrome? He mea hou paha ka inoa iā ʻoe. I ka ʻōlelo maʻalahi, he ʻano ia e kū mai ana i ka wā e hana nui ai ko mākou kino i ka hormone cortisol . Ua kapa pū kekahi poʻe iā ia he hypercortisolism. ʻO ka "syndrome" kahi hōʻiliʻili o nā hōʻailona e hui pū ana. Ua ʻike paha ʻoe iā ia i kapa ʻia ʻo Cushing's syndrome e kekahi poʻe.

No laila he aha kēia cortisol?

He hormone steroid ka Cortisol i loko o ko kākou kino. Kapa pinepine mākou iā ia ʻo ka "hormone stress" no ka mea ke kaumaha mākou, hoʻokuʻu ko mākou kino i ka cortisol hou aku. I loko o kēia mau manawa, kōkua ka cortisol iā mākou:

• Piʻi ka helu o kou puʻuwai.
• Ke piʻi nei kou koko.
• Hoʻomalu i nā pae kō koko.
• Hoʻomalu i ka hanu ʻana.
• Hoʻonui i ka ʻeha o nā ʻiʻo.

ʻAʻole wale ia, akā i ka wā e kaumaha ai mākou, kōkua pū ka cortisol i ka pani ʻana i nā ʻōnaehana i mea nui ʻole i ko mākou kino i kēlā manawa, no ka laʻana, ka ʻōnaehana hoʻoheheʻe a me ka ʻōnaehana hānau keiki.

He hormone koʻikoʻi ka Cortisol no ko kākou kino. He mea nui ka Cortisol no kēia mau mea:

• E mālama i ke koko.
• E hoʻoponopono i nā pae kō koko.
• E hōʻemi i ka mumū.
• Kūkulu i nā hoʻomanaʻo.
• E kāohi i kou hanu ʻana.
• E mālama i ke kaulike o ka paʻakai i loko o ke kino.
• E hoʻolilo i ka meaʻai a kākou e ʻai ai i ikehu.

Hoʻomalu ʻia nā pae Cortisol e ʻelua mau kelepa liʻiliʻi ma luna o ko kākou mau puʻupaʻa, nā kelepa adrenal, ka kelepa pituitary i loko o ka lolo, a me ka hypothalamus, aia ma luna o ka kelepa pituitary.

ʻO ka maʻamau, hoʻokumu ʻia ka maʻi Cushing e kahi puʻupuʻu . Hiki ke hana ʻia kēia ma nā ʻano nui ʻelua:

• Endogenous: ʻO ia hoʻi, he kūlana ia i hoʻokumu ʻia e ka cortisol i hana ʻia i loko o ko mākou kino.
• Exogenous: ʻO ke ʻano kēia, ua hoʻokumu ʻia kahi kūlana e nā kumu o waho ma ke ʻano he hopena ʻaoʻao o kekahi mau lāʻau lapaʻau i lawe ʻia e mālama i nā kūlana olakino ʻē aʻe.

ʻO wai ka mea e loaʻa pinepine ai i ka Cushing Syndrome?

ʻO ka maʻi Cushing ka mea maʻamau i nā keiki, nā ʻōpio, a me nā pākeke. ʻO ia ka mea maʻamau i nā poʻe ma waena o 25 a me 50 mau makahiki. ʻO ka poʻe e lawe ana i nā lāʻau lapaʻau i loaʻa ka cortisol (no ka laʻana, nā lāʻau lapaʻau no ka hānō a me ka rheumatoid arthritis) ʻoi aku ka nui o ka pilikia o ka loaʻa ʻana o ke ʻano. Ma kahi o 70% o ka poʻe me ka maʻi Cushing he mau wahine a he 30% he mau kāne.

Pehea ka maʻamau o kēia kūlana?

He maʻi laha ʻole ka maʻi Cushing, e pili ana ma waena o 40 a me 70 o hoʻokahi miliona mau kānaka i kēlā me kēia makahiki.

He aha ka ʻokoʻa ma waena o ka Cushing Syndrome a me ka maʻi Cushing?

ʻO ka maʻi Cushing kekahi ʻano o ka maʻi Cushing. Hoʻokumu ʻia ia e kahi puʻupuʻu maikaʻi ʻole i loko o ka pituitary gland. Hoʻopuka nui kēia puʻupuʻu i ka hormone ACTH (adrenocorticotropic hormone) . ʻO kēia ke kumu o ka hoʻopuka nui ʻana o nā kelepa adrenal i ka cortisol.

ʻO ka poʻe me ka maʻi Cushing, ʻoi aku ma mua o 70% o nā pākeke a ma waena o 60% a me 70% o nā keiki a me nā ʻōpio i loaʻa i kēia ʻano maʻi Cushing.

He aha ke ʻano o nā kauka e mālama nei i ka Cushing Syndrome?

E kuhikuhi aku kāu kauka lapaʻau iā ʻoe i kahi loea i kapa ʻia he endocrinologist e nānā a mālama i kēia maʻi.

Hiki i ka Cushing Syndrome ke lilo i mea make?

ʻAe, hiki i ka Cushing's Syndrome ke make inā ʻaʻole mālama pono ʻia. Inā waiho ʻole ʻia, hiki i kēia pae cortisol kiʻekiʻe (hypercortisolism) ke alakaʻi i nā ʻano pilikia olakino like ʻole. Eia kekahi laʻana:

• Nā maʻi
• Nā ʻūpā koko, ʻoiai ma nā māmā a me nā wāwae
• Kaumaha
• Maʻi hohola
• Piʻi ke kaumaha
• Nā pilikia hoʻomanaʻo a i ʻole ka paʻakikī i ka noʻonoʻo ʻana
• Ke koko kiʻekiʻe a i ʻole ka cholesterol kiʻekiʻe
• Nā iwi haki
• ʻO ka maʻi diabetes type 2, prediabetes, a i ʻole ka glucose hoʻokē ʻai i hoʻopilikia ʻia

Inā haʻalele ʻia, hiki i ka maʻi Cushing ke alakaʻi i ka make.

He aha nā kumu o ka Cushing Syndrome?

Hoʻokumu ʻia ka maʻi Cushing e nā pae kiʻekiʻe o ka cortisol i loko o ke kino. Aia kekahi mau kumu e hiki ke kōkua i kēia:

• Ka Hoʻohana ʻana i nā Lāʻau Glucocorticoid: Hoʻohana ʻia nā lāʻau Glucocorticoid (no ka laʻana, prednisone) e mālama i ka hānō mau loa, ka rheumatoid arthritis, lupus, sarcoidosis, a me nā maʻi autoimmune ʻē aʻe e hoʻoulu ai i ka mumū mau loa. ʻO ka lawe ʻana i kēia mau lāʻau no ka manawa lōʻihi hiki ke hana i ka "iatrogenic" a i ʻole exogenous Cushing syndrome. ʻO ka huaʻōlelo "iatrogenic" ʻo ia hoʻi ke kumu ʻia kekahi mea ʻē aʻe e kahi lāʻau lapaʻau.
• ʻO nā puʻupuʻu pituitary: ʻO ka maʻi Cushing ( koe naʻe ka iatrogenic Cushing syndrome) i hoʻokumu ʻia e nā puʻupuʻu pituitary e hana nui ana i ka ACTH, kahi hormone e haʻi aku i nā kelepa adrenal e hana i ka cortisol, a hoʻopilikia i 8 o 10 mau kānaka. Ua kapa ʻia kēia ʻano maʻi Cushing.
• Nā puʻupuʻu cortical adrenal: Hiki i kahi puʻupuʻu e ulu ana ma luna o ke kelepa adrenal ke hana i ka nui o ka cortisol. He mau puʻupuʻu benign kēia. Eia nō naʻe, i kekahi manawa hiki i kēia puʻupuʻu ke lilo i carcinoma cortical adrenal, kahi ʻano maʻi ʻaʻai adrenal kakaʻikahi loa.
• ʻO nā puʻupuʻu māmā, pancreas, thyroid a me thymus: Ke hana ʻia ka ACTH e nā puʻupuʻu ma waho o ka pituitary gland, ua kapa ʻia ʻo ia he ectopic ACTH syndrome. He maʻi ʻino kēia mau puʻupuʻu. ʻO ka mea maʻamau o kēia mau mea, ʻo ia ka maʻi kanesa māmā liʻiliʻi.

He maʻi hoʻoilina anei ka Cushing Syndrome?

ʻO ka maʻamau, ʻaʻole . ʻO ka hapa nui o nā hihia o ka Cushing's syndrome ʻaʻole ia he hoʻoilina.

He aha nā hōʻailona o ka Cushing Syndrome?

Ma waho aʻe o nā hōʻailona e pili pono ana i ka maʻi Cushing, aia kekahi mau hōʻailona e like me nā maʻi ʻē aʻe he nui. ʻAʻole like nā hōʻailona o kēlā me kēia kanaka. Eia nā hōʻailona e hiki ke kū mai:

• Piʻi koke ke kaumaha ma ka maka (kapa kekahi he "moon face"), ka ʻōpū, ke kua o ka ʻāʻī (kapa kekahi he "buffalo hump"), a me ka umauma.
• He helehelena ʻulaʻula a poepoe.
• He manawa ka manawa e ho'ōla ai i nā ʻeha.
• Ke koko kiʻekiʻe (hypertension).
• Ka ulu nui ʻana o ka lauoho ma ka maka, ka ʻāʻī, ka umauma, ka ʻōpū, nā umauma, a me nā ʻūhā, a i ʻole ka nalowale o ka lauoho (ʻōhule).
• Ka maʻi diabetes.

ʻO nā hōʻailona ʻē aʻe paha:

• ʻO ke ʻano o nā māka kikoo poni ma ka ʻōpū.
• ʻO ka maʻalahi o ka palapū o nā lima a me nā wāwae.
• Ka nāwaliwali a me ka luhi nui.
• ʻIke pōwehiwehi a me ka poniuniu.
• Ka nāwaliwali o nā ʻiʻo a me ka nāwaliwali o nā lālā.
• Nā loli o ka libido a me ka hana erectile i nā kāne.
• Ka ulu ʻana o nā keiki me ka ʻole o ka hoʻopōpilikia.

Pehea ka lōʻihi o ke ola ʻana o ka Cushing Syndrome?

ʻO ka lōʻihi o ke ola ʻana o ka maʻi Cushing e pili ana i ke ʻano o kāu pane ʻana i ka lāʻau lapaʻau. Hoʻōla ka hapa nui o ka poʻe me nā pae cortisol kiʻekiʻe (hypercortisolism) ma hope o kekahi mau pule o ka lāʻau lapaʻau.

Ke hoʻopilikia nei anei ka Cushing Syndrome i ka hanu ʻana?

ʻAʻole.ʻAʻole ka hanu pōkole kahi hōʻailona maʻamau o ka maʻi Cushing.

Ke kumu nei anei ka Cushing Syndrome i ka osteoporosis?

ʻAe. Hiki i ka maʻi Cushing ke hoʻonāwaliwali i nā iwi. Hiki i kēia ke alakaʻi i nā haki, ʻoiai inā ua loaʻa iā ʻoe ke ʻano no ka manawa lōʻihi. Hiki i nā iwi nāwaliwali ke hoʻoulu i ka ʻeha.

Ke kumu nei anei ka maʻi Cushing i ka hypokalemia?

ʻO ka Hypokalemia kahi kūlana kahi i haʻahaʻa ai ka pae o ka potassium i loko o kou koko. Hiki ke loaʻa kēia kūlana inā loaʻa iā ʻoe ka Cushing's syndrome.

Pehea e ʻike ʻia ai ka Cushing Syndrome?

Inā kānalua kāu kauka i nā pae cortisol kiʻekiʻe (hypercortisolism), aia kekahi mau alakaʻi a lākou e hahai ai. E nīnau lākou i nā nīnau, lawe i kāu mōʻaukala olakino, hana i kahi hoʻokolokolo kino, a laila kauoha i kekahi mau hoʻokolohua lab. Hiki iā lākou ke nānā iā ʻoe no kekahi manawa.

Hiki i kekahi manawa ke paʻakikī iki ka ʻike ʻana i ka maʻi Cushing. Inā ʻoe e haʻi aku i kāu kauka ua luhi ʻoe a ke piʻi nei ke kaumaha, ʻaʻole paha lākou e noʻonoʻo koke e pili ana i ka maʻi Cushing. ʻO kēia no ka mea he mea maʻamau kēia mau hōʻailona i nā maʻi like ʻole.

Eia kekahi, hiki ke huikau ʻia ka maʻi Cushing me ka polycystic ovary syndrome a i ʻole ka metabolic syndrome . Pono kāu kauka e kāpae i nā kūlana ʻē aʻe e hana i kahi hōʻailona.

He aha nā hoʻokolohua e hana ʻia e hōʻoia i ka Cushing Syndrome?

Hiki i kāu kauka ke hana i kekahi o kēia mau hoʻokolohua:

• Hoʻāʻo cortisol mimi 24-hola: Ke ana kēia hoʻāʻo i ka nui o ka cortisol i loko o kou mimi ma nā micrograms (mcg). E noi aku kāu kauka iā ʻoe e hōʻiliʻili i kāu mimi ma luna o kahi manawa 24-hola.
• Hoʻāʻo cortisol salivary waena pō: ʻO ka maʻamau, haʻahaʻa loa nā pae cortisol i ka pō. Nānā kēia hoʻāʻo i nā pae cortisol ma waena o 11 a me 12 am. Inā loaʻa iā ʻoe ka maʻi Cushing, e kiʻekiʻe loa kāu mau pae cortisol i kēlā manawa.
• Hoʻāʻo hoʻopau dexamethasone haʻahaʻa:He lāʻau lapaʻau like ʻo Dexamethasone me cortisol. No kēia hoʻāʻo, lawe ʻoe i hoʻokahi milligram (mg) o kēia lāʻau lapaʻau ma ka waha i ka pō, a laila ana ʻia kou mau pae cortisol ma waena o 8 a me 9 a.m. Nānā kēia hoʻāʻo koko inā ua pane kāu mau kelepa adrenal i ka dexamethasone ma ka hoʻemi ʻana i ka nui o ka cortisol a lākou e huna ai. Inā loaʻa iā ʻoe ka maʻi Cushing, e kiʻekiʻe kou mau pae cortisol.
• Hoʻāʻo koko: Ke ana nei kahi hoʻāʻo koko i ka pae o ka ACTH i loko o kou koko. Inā haʻahaʻa ka pae ACTH, loaʻa paha iā ʻoe kahi puʻupuʻu adrenal. Inā maʻamau a kiʻekiʻe paha ka pae, loaʻa paha iā ʻoe kahi puʻupuʻu pituitary a i ʻole kahi puʻupuʻu ectopic.
• Hoʻāʻo hoʻopau dexamethasone kiʻekiʻe: Ua like kēia me ka hoʻāʻo hoʻopau dexamethasone haʻahaʻa, akā ʻo ka nui he 8 milligrams ma kahi o 1. Hana pinepine ʻia kēia hoʻāʻo ma hope o ka hōʻike ʻana o ka hoʻāʻo haʻahaʻa i nā pae cortisol kiʻekiʻe i ke kakahiaka a hōʻike nā hoʻāʻo koko i nā pae kiʻekiʻe o ACTH i loko o ke koko. Hiki i kēia hoʻāʻo ke kōkua i ka ʻike ʻana i ke kumu o ka maʻi Cushing. Hiki iā ia ke kōkua i ka hoʻokaʻawale ʻana ma waena o kahi adenoma pituitary (i ʻike ʻia hoʻi ʻo ka maʻi Cushing) a me kahi puʻupuʻu ma kahi ʻē aʻe o kou kino (e like me nā māmā).

Ke hōʻoia kāu kauka ua loaʻa iā ʻoe ka maʻi Cushing, ʻo ka hana aʻe e ʻike i ke kumu o ia mea. I ka hapa nui o nā hihia, he lāʻau lapaʻau a he puʻupuʻu paha. Inā ʻoe e lawe ana i nā glucocorticoids, ʻo ia paha ke kumu, no laila e hōʻemi paha kāu kauka i kāu mahele. Inā ʻaʻole ʻoe e lawe ana i nā glucocorticoids, hiki iā ia ke hōʻike i kahi puʻupuʻu i loko o kou mau kelepa adrenal, ke kele pituitary, a i ʻole ma kahi ʻē aʻe. Hiki i kāu kauka ke paipai i nā haʻawina kiʻi e like me kēia e kōkua i ka ʻike ʻana i ka puʻupuʻu:

• ʻO ke scan CAT (CT scan) a i ʻole MRI ʻōpū: Hiki i kāu kauka ke hana i kahi CT scan a i ʻole MRI e ʻike inā he puʻupuʻu kou i loko o kou mau kelepa adrenal. Hiki ke hana ʻia kēia mau scan me a i ʻole me ka ʻole o ka hoʻohālikelike intravenous (IV contrast). He koʻikoʻi loa kēia mau hoʻokolohua no ka ʻike ʻana i nā puʻupuʻu adrenal.
• ʻO ke kiʻi hoʻohālikelike magnetic (MRI) o ka pituitary:Lawe kahi MRI i nā kiʻi o kou kelepa pituitary e ʻimi i kahi puʻupuʻu. I kekahi mau hihia, ʻaʻole he hōʻailona piha ka MRI. Ma kahi o 50% o ka poʻe me ka Cushing's syndrome he MRI "maʻamau", ʻoiai he 10% paha he mau puʻupuʻu e pili ʻole ana i ka syndrome.
• ʻO ka laʻana sinus petrosal inferior bilateral (BIPPS): Loaʻa i kēia hoʻāʻo ke kumu o ka hoʻokuʻu ʻia ʻana o ACTH. Hoʻokuʻu ʻia ʻo ACTH a me nā hormones pituitary ʻē aʻe mai ka pituitary gland i loko o ke koko. Hana kekahi radiologist interventional akamai i kēia hoʻāʻo ma o ʻelua mau aa koko i kapa ʻia ʻo nā sinuses petrosal inferior. ʻO ka helu pololei o kēia hoʻāʻo ma waena o 95% a me 98%.
• ʻO ka CT scan umauma: Inā kānalua kāu kauka i kahi puʻupuʻu ectopic, hiki iā lākou ke kauoha i kahi CT scan o ka umauma e nānā i ka maʻi kanesa o ka māmā.

Pehea e mālama ʻia ai ka Cushing Syndrome?

ʻO ke ʻano o ka lāʻau lapaʻau e pili ana i ke kumu nui o nā pae cortisol kiʻekiʻe. Inā ʻoe e lawe ana i nā glucocorticoids, e hōʻemi paha kāu kauka i kāu mahele lāʻau a kuhikuhi paha i kahi lāʻau lapaʻau ʻaʻole glucocorticoid.

Inā hana ʻia ka maʻi Cushing e kahi puʻupuʻu, hiki i kāu kauka ke kuhikuhi i ke ʻoki ʻana a i ʻole ka radiation therapy.

ʻO kekahi koho ʻē aʻe, ʻo ia ke kuhikuhi ʻana o kāu kauka i kahi lāʻau lapaʻau e hōʻemi ana i ka hana cortisol, e like me ketoconazole. Pono paha ʻoe e hana pū me kekahi mau kauka like ʻole e mālama i ka puʻupuʻu a me nā hōʻailona o ka maʻi Cushing.

• Kemoterapi: Inā he maʻi kanesa kahi puʻupuʻu a ua pālahalaha i nā ʻāpana ʻē aʻe o ke kino, pono paha ka chemotherapy. E kamaʻilio me kāu kauka e pili ana i nā hopena ʻaoʻao.
• Nā lāʻau lapaʻau: Ke hoʻohui nei i nā lāʻau lapaʻau e hoʻohaʻahaʻa i ka cortisol a i ʻole ke wehe ʻana i nā lāʻau lapaʻau e hiki ai ke hana i ka Cushing's Syndrome.
• Pāhawewe: ʻAʻole paha e wehe ʻia kahi puʻupuʻu pituitary ma ke ʻoki ʻana. I kēlā mau hihia, pono paha ʻoe e hana i ʻeono pule o ka radiation therapy. Hiki ke hala nā makahiki no ka hoʻi ʻana o nā pae cortisol i ka maʻamau. E kamaʻilio me kāu kauka e pili ana i nā hopena ʻaoʻao.
• ʻO ke ʻoki kino:Ua holomua ka wehe ʻana i nā ʻōpū pituitary, nā ʻōpū adrenal, a me nā ʻōpū ectopic ma ke ʻoki ʻana, akā pono ʻoe e hoʻololi i nā pae cortisol hou a haʻahaʻa. I loko o kēia manawa, pono paha ʻoe e lawe i ka lāʻau cortisol ma ke ʻano o nā pila hydrocortisone. Hiki iā ʻoe ke hoʻōki i ka lawe ʻana i kēia lāʻau ma hope o 6 a 18 mau mahina. I ka hapa nui o nā hihia, ma hope o ke ʻoki laparoscopic, hiki iā ʻoe ke haʻalele i ka haukapila i hoʻokahi a ʻelua paha lā.

Inā mālama pono ʻia ka maʻi Cushing, hiki ke hala ma waena o 2 a 18 mau mahina e hoʻōla ai. E noho pili loa me kāu kauka i kēia manawa a ma hope aku.

He aha kaʻu e manaʻo ai inā loaʻa iaʻu ka Cushing Syndrome?

Hiki i kāu kauka ke mālama i ka maʻi Cushing a pono ia e mālama. Inā ʻaʻole mālama ʻia, hiki ke make. E ʻike i ke kauka i ka wā hikiwawe e kūkākūkā i kāu mau hōʻailona me kāu kauka.

Hiki ke hoʻonui i ka ʻino o ka Cushing Syndrome?

Hiki i ka maʻi Cushing ke ʻoi aku ka ʻino inā ʻaʻole mālama pono ʻia. E hoʻomau i ka launa pū me kāu kauka a e haʻi iā lākou e pili ana i nā hōʻailona hou, nā hōʻailona e ʻoi aku ka ʻino, a i ʻole nā ​​​​pilikia ʻē aʻe.

Pehea e hiki ai iaʻu ke hōʻemi a pale aku paha i ka pilikia o Cushing Syndrome?

Pono kou kino i ka cortisol i nā manawa a pau. Pono ʻoe iā ia e noho ikaika. Hoʻomalu ia i kou hanu ʻana, hoʻolilo i ka meaʻai āu e ʻai ai i ikehu, hoʻoponopono i kou pae kō koko, kōkua iā ʻoe e hoʻoponopono i ke kaumaha, a hana nui aku. ʻAʻole ʻo Cortisol ka ʻenemi o kou kino, akā ʻo ka nui ʻole o ia mea ʻaʻole maikaʻi. Eia naʻe, ʻaʻole hiki iā ʻoe ke ola me ka ʻole o ka cortisol.

Inā ʻoe e lawe ana i nā glucocorticoids a i ʻole nā ​​steroids, e nānā pono kāu kauka i kāu mau pae cortisol. ʻO ka mea pōʻino, ʻaʻohe ala e pale aku ai i kahi puʻupuʻu mai ka hoʻoulu ʻana i ka Cushing's Syndrome (hypercortisolism).

He aha ke ʻano o ka noho ʻana me ka Cushing Syndrome?

Hiki ke paʻakikī ke ola me ka maʻi Cushing, akā, ʻaʻole pono ia he maʻi e hoʻoweliweli i ke ola. Aia nā kauka i aʻo ʻia e kōkua iā ʻoe, a aia nā lāʻau lapaʻau. Hiki i kēia mau lāʻau lapaʻau ke ho'ōla i ka maʻi Cushing a hoʻomaikaʻi i nā hōʻailona o nā pae cortisol kiʻekiʻe (hypercortisolism).

Hiki i ka maʻi Cushing ke hoʻoulu iā ʻoe e ʻike i kekahi mau pilikia naʻau a me nā pilikia pili kanaka. Hilahila paha kekahi poʻe i ka hāʻule ʻana o ka lauoho, ka ulu nui ʻana o ka lauoho, a/a i ʻole ka piʻi ʻana o ke kaumaha ma ka maka a me ke kua o ka ʻāʻī. ʻO ka "moon face" a me ka "buffalo hump" e hoʻohālua paha iā ʻoe e pili ana i ke komo ʻana i nā kūlana pili kanaka. I ka hala ʻana o ka manawa, hiki i ka lāʻau lapaʻau ke kōkua i ka hoʻomaikaʻi ʻana i kēia mau hōʻailona. Hiki i ka maʻi Cushing ke hoʻoulu i ke kaumaha a me nā maʻi noʻonoʻo ʻē aʻe. Inā pono, e ʻike i kahi mea lapaʻau no ke aʻo ʻana a me kahi psychiatrist no ka lāʻau lapaʻau e kōkua iā ʻoe e hana me nā hopena naʻau o nā pae cortisol kiʻekiʻe (hypercortisolism).

Āhea wau e ʻike ai i ke kauka?

E ʻike i ke kauka inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona o Cushing's syndrome:

Nā hōʻailona e pili pono ana i nā wahine:

• Ka ulu ʻana o ka lauoho maka hou a nui paha.
• Ka loli ʻana o ka makemake moe kolohe.
• Ka loli ʻana o ke kaʻina hana menstrual.

Nā hōʻailona e pili ana i nā mea āpau:

• Piʻi koke ke kaumaha ma ka maka (kapa kekahi he "moon face"), ka ʻōpū, ke kua o ka ʻāʻī (kapa kekahi he "buffalo hump"), a me ka umauma.
• He helehelena ʻulaʻula a poepoe.
• Ke koko kiʻekiʻe (hypertension).
• Ka ulu nui ʻana o ka lauoho ma ka maka, ka ʻāʻī, ka umauma, ka ʻōpū, a me nā ʻūhā.
• Ka maʻi diabetes.
• ʻAkeka hou a nui paha.
• ʻO ke ʻano o nā māka kikoo poni ma ka ʻōpū.
• ʻO ka maʻalahi o ka palapū o nā lima a me nā wāwae.
• Ka nāwaliwali a me ka luhi nui.
• ʻIke pōwehiwehi a me ka poniuniu.
• He manawa ka manawa e ho'ōla ai i nā ʻeha.
• Ka nāwaliwali o nā ʻiʻo.

He aha nā nīnau e pono iaʻu e nīnau aku i kaʻu kauka?

• He aha nā lāʻau lapaʻau e hiki iaʻu ke lawe e kōkua ai i kaʻu Cushing's Syndrome?
• Aia kekahi mau hoʻoikaika kino e hiki iaʻu ke hana e kōkua ai i koʻu mau ʻiʻo nāwaliwali?
• Aia kekahi mau lāʻau lapaʻau e hiki ke hoʻohana ʻia e kōkua ai me nā māka hoʻolōʻihi?
• Pono anei au e ʻike i kahi loea no ka Cushing Syndrome?
• Pono anei iaʻu e hoʻōki i ka lawe ʻana i kekahi o nā lāʻau lapaʻau aʻu e lawe nei i kēia manawa?
• He aha ka lāʻau lapaʻau maikaʻi loa noʻu?
• Aia kekahi mau hana pale ʻē aʻe e pono iaʻu e hana?

Hiki i ka maʻi Cushing ke lilo i maʻi paʻakikī e hoʻoponopono ai. Hiki iā ia ke hoʻoulu i ka nāwaliwali, ke koko kiʻekiʻe, a me ka luhi. Hiki ke paʻakikī nā lāʻau lapaʻau e like me ke ʻoki kino, ka lāʻau lapaʻau, ka radiation therapy, a me ka chemotherapy. Akā, kūpono lākou, no ka mea , me ka lāʻau kūpono, hiki ke ho'ōla ʻia ka maʻi Cushing.

Hōʻuluʻulu Manaʻo (Leka Lawe-Home)

ʻO ka Cushing's Syndrome kahi maʻi i hoʻoulu ʻia e ka piʻi ʻana o ka hormone cortisol i loko o ko mākou kino. He mea kākaʻikahi kēia, akāInā ʻike ʻia a mālama pono ʻia, hiki ke ho'ōla ʻia . He mea nui loa ka ʻimi ʻana i ke aʻo lapaʻau inā loaʻa iā ʻoe nā hōʻailona e like me ka pehu ʻana o ka maka, ka piʻi ʻana o ke kaumaha, ka ulu nui ʻana o ka lauoho, a i ʻole ke koko kiʻekiʻe. ʻOkoʻa nā koho lapaʻau ma muli o ke kumu. No laila e kamaʻilio me kāu kauka e pili ana i nā mea āpau a hahai i kā lākou ʻōlelo aʻo. E hoʻomanaʻo, ʻaʻole ʻoe hoʻokahi, a loaʻa ke kōkua.

ʻO Cushing's Syndrome, cortisol, hormones, adrenal glands, pituitary gland, ACTH, nā hōʻailona, ​​​​lāʻau lapaʻau, endocrinologist