He mau kiko a puʻupuʻu paha kou ma kou ʻili? He Cutaneous B-Cell Lymphoma paha kēia?

He mea kupanaha ko kākou ʻili, ʻeā? I kekahi manawa hele mai nā pimples liʻiliʻi a me nā kiko a hele aku. Akā i kekahi manawa kānalua paha ʻoe e pili ana i kahi kiko hou a puʻupuʻu paha ma kou ʻili, a i ʻole kahi mea lōʻihi i hoʻōla ʻole ʻia. I kēlā mau manawa, pono mākou e akahele iki. No ka mea, ʻoiai he mea kakaikahi loa, hiki i kēlā mau loli ʻili ke lilo i hōʻailona o kahi maʻi koʻikoʻi. I kēia lā e kamaʻilio mākou e pili ana i kahi maʻi ʻili kakaikahi, akā he mea nui loa e makaʻala ai. ʻO ia ke ʻano i kapa ʻia ʻo cutaneous B-cell lymphoma, a i ʻole `(Cutaneous B-Cell Lymphoma)`.

He aha ka Cutaneous B-Cell Lymphoma?

I ka ʻōlelo maʻalahi, ʻo Cutaneous B-Cell Lymphoma (CBCL) kahi ʻano maʻi kanesa e hoʻomaka ana i loko o kou ʻili. He mea kākaʻikahi iki ia. No loko ia o kahi hui o nā maʻi kanesa i kapa ʻia ʻo lymphoma. Akā ʻo ka mea kūikawā, hoʻomaka ia ma waho o ko mākou mau lymph nodes, i loko o ka ʻili. ʻO ia ke kumu i kapa ʻia ai he lymphoma extranodal.

ʻO ka hapa pinepine, ʻike ʻia kēia `(CBCL)` ma ke ʻano he kiko, ʻulaʻula, a puʻupuʻu paha ma ka ʻili. Ulu mālie kēia mau mea. Hiki ke hala nā mahina, a hiki i nā makahiki, no ko lākou ulu ʻana. Eia kekahi, ʻaʻole lākou e laha pinepine i nā wahi ʻē aʻe o ke kino. Kapa pū kekahi poʻe iā ia he `(B-cell skin lymphoma)`. No laila, inā ʻike ʻoe i kahi mea hou a ʻokoʻa paha ma kou ʻili, he manaʻo maikaʻi e hoʻolohe iā ia.

Pehea e ulu ai kēia lymphoma? He aha nā B-cell?

I kēia manawa, ke noʻonoʻo nei paha ʻoe no ke aha e hana ai kekahi mea e like me kēia. ʻO kaʻoiaʻiʻo, ʻaʻole i ʻike nā kānaka ʻepekema i ke kumu pololei o kēia `(CBCL)`. Akā hoʻokahi mea i maopopo: ʻaʻole ia he hoʻoilina a he maʻi lele paha.

Hoʻomaka ia me nā hunaola koko keʻokeʻo i kapa ʻia ʻo lymphocytes. He mau lālā koʻikoʻi kēia mau lymphocytes o kā mākou ʻōnaehana pale. Ua like lākou me ka pūʻali koa e pale ana i ko mākou ʻāina. ʻElua ʻano nui o nā lymphocytes: nā hunaola T a me nā hunaola B. Ke hoʻomaka nā hunaola B e ulu nui me ka ʻole o ke kaohi ʻana, hiki mai kēia ʻano i kapa ʻia ʻo B-cell lymphoma. I ka ʻōlelo maʻalahi, hele iki ko mākou mau hunaola ponoʻī a lilo i mau hunaola maʻi ʻaʻai.

He aha nā ʻano nui o ka lymphoma B-cell cutaneous?

ʻEhā ʻano nui o kēia "(CBCL)". Ua hoʻokaʻawale ʻia kēia mau mea ma muli o ke ʻano o nā cell ma lalo o kahi microscope. Hiki i kēlā me kēia ʻano ke ʻano like ʻole ma ka ʻili a pono paha nā ʻano lapaʻau like ʻole.

1. ʻO ka lymphoma kikowaena follicle ʻili mua:

• ʻO kēia ke ʻano i ʻike pinepine ʻia o `(CBCL)`.
• ʻO ka hapa pinepine, ʻike ʻia lākou ma ke poʻo, ka ʻāʻī, a i ʻole ka umauma/kino.
• ʻIke ʻia ia he ʻulaʻula-ʻeleʻele, nā nodules i hoʻokiʻekiʻe ʻia a i ʻole nā ​​​​​​huapalapala ma ka ʻili .
• He mea koʻikoʻi loa kēia, e ulu ana ma nā mahina, a i ʻole he mau makahiki.

2. ʻO ka lymphoma B-cell ʻāpana ʻili mua:

• He ʻano ulu maikaʻi nō hoʻi kēia.
• ʻIke pinepine ʻia ia he mau ʻeha ʻulaʻula-ʻulaʻula, nodules, a i ʻole nā ​​​​​​puʻupuʻu .
• ʻIke pinepine ʻia ia ma ke kino a i ʻole nā ​​​​lima.

3. ʻO ka lymphoma B-cell nui i hoʻolaha mua ʻia ma ka ʻili, ʻano wāwae:

• He ʻuʻuku iki kēia ma mua o nā ʻano ʻelua ʻē aʻe, akā ʻoi aku ka huhū. ʻO ia hoʻi, ulu koke ia, i loko o kekahi mau pule a i ʻole mau mahina.
• Hoʻike pinepine ʻia ia ma ke ʻano he hoʻokahi a ʻoi aku paha mau puʻupuʻu a i ʻole nā ​​​​nodules ma nā wāwae, nā lima, a i ʻole ka umauma/kino.

4. ʻO ka lymphoma B-cell nui i hoʻolaha ʻia ma ka ʻili mua, nā mea ʻē aʻe:

• He ʻano laha ʻole a huhū loa kēia.
• Hiki ke ʻokoʻa ke ʻano, akā hoʻomaka pinepine ia ma ke poʻo, ke kino, a me nā lālā.

ʻO wai ka mea i loaʻa pinepine i kēia maʻi? Pehea ka maʻamau?

ʻOiaʻiʻo, hiki ke ulu kēia kūlana i kapa ʻia ʻo ``(CBCL)`` i loko o kekahi. ʻAʻohe ʻokoʻa o ke kāne a me ka wahine, ʻaʻohe ʻokoʻa o ka makahiki, a ua ʻike ʻia e ulu ana i nā lāhui like ʻole. No laila, he mea paʻakikī ke noʻonoʻo, "ʻAʻole e hiki mai kēia iaʻu."

Akā, mai hopohopo. He maʻi laha ʻole kēia. E noʻonoʻo, inā ʻoe e lawe i ka awelika o hoʻokahi miliona mau kānaka, ʻehā wale nō o lākou e loaʻa i kēia. No laila, ʻaʻole pono ʻoe e hopohopo a manaʻo he "(CBCL)" kēia i ka manawa āu e ʻike ai i kahi mea ʻē ma kou ʻili. Eia nō naʻe, inā he kānalua kāu, he mea naʻauao ke ʻimi i ka ʻōlelo aʻoaʻo lapaʻau.

He aha nā hōʻailona? E nānā inā loaʻa iā ʻoe kēia mau hōʻailona pū kekahi

ʻO ka hōʻailona nui o ka `(CBCL)` ʻo ia nā loli i ka ʻili. Hiki ke ʻike ʻia kēia mau mea ma nā ʻano like ʻole:

• He ʻōhū
• He puʻupuʻu a puʻupuʻu paha ma ka ʻili
• He puʻupuʻu liʻiliʻi (nodule a tumor paha)

Hiki i kēia ke ʻulaʻula, poni, a ʻeleʻele paha. Ua piʻi a paʻa kekahi, akā laumania. Ua kapa ʻia kēia mau papules. ʻO kekahi he pālahalaha, e like me nā ʻāpana o ka ʻili mānoanoa. Ua kapa ʻia kēia mau plaques. Ua kapa ʻia hoʻi nā puʻupuʻu nui he nodules a he tumors paha.

Hiki ke loaʻa hoʻokahi wale nō wahi/puʻupuʻu, a i ʻole he nui. Eia kekahi, hiki ke ʻike ʻia lākou ma kahi hoʻokahi ma ke kino a i ʻole ma kekahi mau wahi. Aia paha lākou ma kahi kokoke kekahi i kekahi, a mamao paha.

E noʻonoʻo, he wahi ʻulaʻula liʻiliʻi ko ʻAnakala Sunil ma kona lima no nā mahina. Ua manaʻo ʻo ia he ʻōpala wale nō ia. Akā ua ulu mālie a lilo i mea nui a like me kahi puʻupuʻu. ʻO ia ka mea hiki ke lilo i hōʻailona mua o kēia.

I ka liʻiliʻi loa, hiki i kekahi poʻe ke ʻike i nā hōʻailona ʻē aʻe. Ua kapa ʻia kēia mau mea he "nā hōʻailona B". ʻO kēia mau mea:

• Ke kuni e hiki mai ana me ke kumu ʻole.
• Ka hou nui ʻana i ka pō.
• Ka pehu ʻana o nā lymph nodes ma ka ʻāʻī, nā armpits, a i ʻole ka groin.
• Ka pohō kaumaha me ke kumu ʻole.

ʻO ke alo o kēia mau "hiʻohiʻona B" ʻo ia hoʻi ua pālahalaha iki aku paha ka maʻi. Eia naʻe, he mea kakaikahi loa kēia ma `(CBCL)`.

Pehea e ʻike ai nā kauka i kēia?

Hoʻopaneʻe ka nui o ka poʻe i ka ʻimi ʻana i ke aʻo lapaʻau no ka mea hiki i nā kiko a me nā puʻupuʻu e kū mai ana ma ka ʻili ma CBCL ke like me ka ʻākena maʻamau, nā nahu pepeke, nā maʻi ʻaleka, nā ʻōpala, a i ʻole nā ​​​​maʻi ʻili ʻē aʻe e like me ka eczema a i ʻole psoriasis. Eia nō naʻe, inā he mea ʻē kou ma kou ʻili ʻaʻole e ho'ōla nei, pono ʻoe e ʻike i ke kauka, ʻoiai ke kauka dermatologist.

E hana mua ke kauka i kahi hoʻokolokolo kino piha o kou ʻili. E nānā lākou i nā wahi āpau o kou kino a loiloi i nā mea ʻē.

A laila, no ka ʻike maopopo ʻana i ka maʻi, pono ka "biopsy ʻili", ʻo ia hoʻi ka lawe ʻana i kahi ʻāpana ʻili liʻiliʻi mai kahi ʻano ʻē a nānā iā ia. Nānā ʻia kēia ʻāpana ʻili liʻiliʻi ma lalo o kahi microscope e kahi loea ("pathologist") e ʻike inā he mau hunaola kanesa, a inā pēlā, he aha ke ʻano o lākou. ʻO ka "biopsy" wale nō ke ala e ʻike pono ai inā he "lymphoma ʻili" a he aha ke ʻano o ia ʻano.

No ka ʻike ʻana inā ua pālahalaha ke kanesa, hiki i kāu kauka ke kauoha i nā hoʻokolohua hou aʻe ('nā hoʻokolohua staging'). Hiki i kēia mau mea ke komo pū me:

• Nā hoʻāʻo koko.
• Nā hoʻokolohua kiʻi e like me ka CT scan a i ʻole PET scan.
• ʻO ka biopsy iwi.
• ʻO ka biopsy o nā kīʻaha lymph.

E aʻo kākou e pili ana i nā pae a me ka laha ʻana o ka maʻi.

ʻO ke kahua o ka maʻi (CBCL) kahi ana o ka laha ʻana o ke kanesa a me ka mamao o kona laha ʻana. He mea nui loa kēia kahua no ka mea e hoʻoholo ai i ka lāʻau lapaʻau. E wehewehe kāu kauka iā ʻoe i ke kahua o ka maʻi a pehea e hoʻopilikia ai iā ʻoe.

• Pae 1E: ʻO ke "E" ke kū nei no "extranodal," ʻo ia hoʻi ma waho o nā lymph nodes. I kēia pae, ua kaupalena ʻia ke kanesa i ka ʻili a ʻaʻole i laha ma kahi ʻē aʻe. Inā ʻaʻohe hōʻailona "B" hou aʻe, e like me ke kuni a i ʻole ka pohō kaumaha, ua kapa ʻia kēia ʻo "Stage 1AE."

Inā ua pālahalaha ka "CBCL", hoʻohana nā kauka i kahi ʻōnaehana i kapa ʻia ʻo "TNM staging system".

• ʻO ka puʻupuʻu (T): ʻO ka leka "T" e pili ana i ka helu o nā papules, nodules, a i ʻole nā ​​puʻupuʻu ma ka ʻili, pehea ko lākou nui, a me ko lākou wahi. Ua helu ʻia kēia mai 1 a 3 (mai ka liʻiliʻi a i ka ʻino loa).
• Nā Pūnaehana (N):Hōʻike ka leka "N" inā ua hoʻopilikia ʻia nā lymph nodes, ehia, a ma hea lākou. Ua helu ʻia kēia mai ka 0 a i ka 3.
• Metastasis (M): Hōʻike ka leka "M" inā ua pālahalaha ka lymphoma ma ʻō aku o ka ʻili a i ʻole nā ​​​​​​kikowaena lymph (`M1`) a i ʻole (`M0`). ʻO ke ʻano o ka `(Metastasis)` ua pālahalaha ke kanesa i nā ʻōpū mamao.

He aha nā lāʻau lapaʻau? Hiki ke ho'ōla ʻia?

ʻO ka lāʻau no ka `(CBCL)` e pili ana i ke ʻano a me ke kahua o ka maʻi. Hiki ke ho'ōla pinepine ʻia, ʻoiai hoʻi i nā ʻano holomua. Eia nō naʻe, i kekahi manawa hiki i ka maʻi ke `hoʻi hou`.

Aia kekahi mau koho lapaʻau:

• Nānā pono: I kekahi mau hihia kahi e ulu ana ka maʻi a ʻaʻole hoʻi e hoʻopilikia nui, hiki i nā kauka ke hoʻohana i kahi ala "nānā a kali". ʻO ia hoʻi, nānā lākou i ka maʻi a hiki i ka hoʻomaka ʻana o ka lāʻau lapaʻau.
• Kemoterapi: Ke hāʻawi ʻana i nā lāʻau lapaʻau e pepehi i nā hunaola kanesa. Hiki ke lawe ʻia kēia mau mea ma ke ʻano he mau pila a i ʻole e hāʻawi ʻia ma ke ʻano he mau inikini.
• Nā lāʻau lapaʻau topical a i ʻole injectable: Hiki ke hoʻopili ʻia nā lāʻau lapaʻau e like me corticosteroids i ka ʻili a i ʻole e hoʻokomo pololei ʻia i loko o ka puʻupuʻu.
• Nā antibodies monoclonal: No kēia hui nā lāʻau lapaʻau e like me `(Rituximab)`. Hana kēia mau mea ma ke ʻano he mau lāʻau lapaʻau i kuhikuhi ʻia a luku i nā cell-B.
• Lapaʻau radiation: ʻO ka hoʻohana ʻana i nā kukuna ikehu kiʻekiʻe e luku i nā hunaola kanesa. He mea kūpono pinepine kēia no nā puʻupuʻu kūloko.
• Wehe ʻana i ke ʻoki kino: I kekahi manawa, inā he puʻupuʻu hoʻokahi, hiki ke wehe loa ʻia me ke ʻoki kino.

E kūkākūkā kāu kauka me ʻoe i ke ʻano lapaʻau kūpono loa iā ʻoe.

Aia kekahi ala e pale aku ai i kēia mai ka hana ʻana?

ʻO ka mea pōʻino, ʻoiai ʻaʻole ʻike ʻia ke kumu kikoʻī o `(CBCL)`, ʻaʻohe ala i hōʻoia ʻia e pale aku ai. No laila, ʻo ka mea maikaʻi loa hiki iā mākou ke hana, ʻo ia ka makaʻala i nā loli ʻē aʻe i ko mākou ʻili a ʻimi koke i ke kōkua lapaʻau inā ʻike mākou i kekahi mea.

He aha ka wānana? (Wānana)

ʻO ka wānana, a i ʻole ka nānā ʻana, e pili ana i kekahi mau kumu, ʻo ke ʻano nui o ka lymphoma a me ke kahua o ka maʻi.

• ʻO nā ʻano ʻelua i maʻamau loa (ʻO ka primary cutaneous follicle center lymphomaʻ a me ka ʻO ka primary cutaneous marginal zone B-cell lymphomaʻ): He ʻelima makahiki ka nui o ke ola o kēia mau mea ma kahi o 95%. ʻO ia hoʻi, ʻelima mau makahiki ma hope o ka hōʻoia ʻana, 95 o 100 o kēia mau maʻi e ola nei. He ʻano maikaʻi loa kēia.
• ʻO nā ʻano ʻino loa (ʻO ka lymphoma B-cell nui diffuse cutaneous mua, ʻano wāwae` a me `ʻē aʻe`): He ʻelima makahiki ka nui o ke ola o kēia mau mea ma kahi o 60%.

He awelika wale nō kēia mau helu. Hiki ke ʻoi aku ka maikaʻi a ʻoi aku paha ka maikaʻi ʻole o kou kūlana, no laila ʻoi aku ka maikaʻi o ke kamaʻilio ʻana me kāu kauka e pili ana i kēia.

Hiki iaʻu ke hoʻi mai ma hope o ka lāʻau lapaʻau?

ʻAe, hiki i ka lymphoma ʻili ke hoʻi hou ma hope o ka mālama ʻana. Hiki i nā puʻupuʻu ke hoʻi mai ma kahi like a i ʻole ma kahi hou. ʻO ka hapa pinepine, hoʻi mai ka ʻano like. Eia naʻe, he mea kākaʻikahi loa, hiki i ka CBCL relapsed ke lilo i maʻi ʻōnaehana a i ʻole kekahi ʻano lymphoma ʻē aʻe.

No laila, he mea nui loa e nānā pinepine i kou ʻili ('skin checks') a hana i nā nānā maʻamau me ke kauka dermatologist a i ʻole kekahi loea ʻē aʻe.

Pehea ʻoe e mālama ai i kou olakino ma ke ʻano he kanaka me CBCL?

Inā loaʻa iā ʻoe (CBCL) a i ʻole ua loaʻa mua iā ʻoe a ua hoʻōla ʻia, he mea nui loa ia e hahai i nā ʻōlelo a kāu kauka. Pono ʻoe e hoʻomau i nā hoʻokolohua e hōʻoia ʻaʻole i hoʻi hou mai ka maʻi.

ʻO ka pinepine o ka hana ʻana o kēia mau hoʻokolohua e loli ma muli o ke ʻano o CBCL a me kona ʻano huhū. Hiki ke hana ʻia i kēlā me kēia mau pule, i kēlā me kēia mau mahina, a i ʻole hoʻokahi manawa i ka makahiki. Hiki i kēia mau manawa hoʻopaʻa ke komo pū me nā hoʻokolohua ʻili, nā hoʻokolohua koko, nā x-ray, a i ʻole nā ​​biopsies.

Nā nīnau āu e nīnau pono ai i kāu kauka

Inā ua ʻike ʻia ʻoe me ka `(Cutaneous B-Cell Lymphoma)`, mai poina e nīnau i kāu kauka i kēia mau nīnau:

• He aha ke ʻano `(CBCL)` aʻu?
• I ke kahua hea kēia?
• He aha ke ʻano o ka lāʻau lapaʻau āu e paipai nei?
• He aha nā hopena ʻaoʻao a me nā pilikia o kēlā mau lāʻau lapaʻau?
• He aha kaʻu wānana?
• ʻEhia ka lōʻihi e ʻike ai inā ua holomua ka lāʻau lapaʻau a ʻaʻole paha?
• ʻEhia mau manawa e pono ai iaʻu e ʻike iā ʻoe e hōʻoia ʻaʻole i hoʻi mai ka lymphoma?

E kōkua nā pane i kēia mau nīnau iā ʻoe e hoʻomaopopo maikaʻi i ka maʻi a me nā hana aʻe.

Leka Lawe-Home mai ka Mea a Mākou i Kamaʻilio Nei

ʻO ka Cutaneous B-Cell Lymphoma kahi ʻano maʻi kanesa kakaikahi e hoʻomaka ana i loko o nā pūnaewele i kapa ʻia he lymphocytes i loko o ka ʻili.

• Ulu mālie ka hapa nui o nā hihia a ʻaʻole e laha i nā ʻāpana ʻē aʻe o ke kino. Eia nō naʻe, hiki i kekahi mau ʻano ke lilo i mea hoʻouka a laha.
• Inā ʻike ʻoe i kahi puʻupuʻu hou, kahi kiko, a i ʻole ka ʻulaʻula ma kou ʻili, mai hoʻowahāwahā iā ia. E ʻike koke i ke kauka, ʻoiai he kauka ʻili.
• Hiki ke ho'ōla ʻia nā ʻano CBCL he nui me ka ʻike mua ʻana a me ka mālama kūpono.
• No ka mea, hiki ke hoʻi hou mai ka maʻi ma hope o ka mālama ʻia ʻana,He mea nui e hoʻāʻo ʻia i nā manawa i kauoha ʻia e ke kauka.

E hoʻomanaʻo, no nā kumu hoʻonaʻauao wale nō kēia ʻike. Inā he mau hopohopo olakino kou, ʻoi aku ka maikaʻi o ka ʻimi ʻana i ke kōkua lapaʻau.

ʻO ka Lymphoma Cell-B ʻili, Kanesa ʻIli, Lymphoma, Cell-B, Nā Puʻupuʻu ʻIli, Maʻi ʻIli