Ua manaʻo paha ʻoe ua nāwaliwali iki kou mau ʻiʻo, a i ʻole ʻaʻole lākou e hana maikaʻi e like me kou manaʻo? I kekahi manawa, kaumaha paha kou mau maka, paʻa paha kou alelo i kou ʻōlelo ʻana, a paʻakikī paha iā ʻoe ke ale. Hana nā kauka i nā hoʻokolohua kūikawā e ʻike i kekahi mau kūlana e hoʻoulu ai i kēia mau hōʻailona. I kēia lā, e kamaʻilio mākou e pili ana i kahi inikini e hiki ke kōkua me kēlā hoʻokolohua, a me ka ʻike pehea e pane ai kou kino i kekahi mau lāʻau lapaʻau. Ua kapa ʻia ʻo ia he edrophonium .
He aha ka Edrophonium? He aha kāna hana?
I ka ʻōlelo maʻalahi, he lāʻau lapaʻau ʻo Edrophonium e hoʻopilikia i kā mākou ʻōnaehana nerve . I mea e hana ai ko mākou mau ʻiʻo, pono e hoʻouna ʻia nā leka mai nā aʻalolo i nā ʻiʻo. I kekahi manawa, hiki ke loaʻa kahi hoʻopilikia iki i ka hoʻouna ʻana o kēia mau leka. ʻO ia ka manawa e hele mai ai ʻo Edrophonium e hoʻopakele.
I kēia manawa, e nānā kākou i ka mea i hoʻohana nui ʻia ai kēia no:
1. No ka ʻike ʻana i ka Myasthenia Gravis:
ʻOiai he inoa paʻakikī kēia, ʻo ka myasthenia gravis kahi maʻi e nāwaliwali ai a luhi koke ai ko kākou mau ʻiʻo. E noʻonoʻo, ala ʻoe i ke kakahiaka me ka manaʻo maikaʻi, akā i ka hala ʻana o ka lā, hoʻomaka kou kino e nāwaliwali, kaumaha kou mau lihilihi a ʻaʻole hiki iā ʻoe ke wehe iā lākou, paʻakikī kāu mau ʻōlelo ke ʻōlelo ʻoe, a paʻakikī paha ʻoe i ka moni ʻana. Hāʻawi ʻia kahi kanaka me kēia mau hōʻailona i kahi inikini o ka edrophonium e ʻike inā hoʻomaikaʻi nā hōʻailona. Inā hana lākou, he hōʻailona ikaika ia he myasthenia gravis paha.
2. E nānā i ka pane i ka lāʻau lapaʻau i hāʻawi ʻia i nā poʻe me Myasthenia Gravis:
Inā ke mālama ʻia nei kekahi no ka myasthenia gravis, hoʻohana ʻia ka hoʻāʻo edrophonium e ʻike ai inā e hana pono ana ka lāʻau lapaʻau, ua lawa, a keu paha.
3. Hoʻopau i nā hopena o nā mea hoʻomaha ʻiʻo i hoʻohana ʻia i ka wā o kekahi mau ʻoki kino:
I ka wā e hana ʻia ai ke ʻoki kino nui, hāʻawi ʻia nā lāʻau lapaʻau kūikawā i kekahi manawa e hoʻomaha ai i nā ʻiʻo o ka mea maʻi. Ma hope o ke ʻoki kino, hiki ke hoʻohana ʻia ka edrophonium e hoʻohuli koke i nā hopena o kēia mau lāʻau lapaʻau a kōkua i nā ʻiʻo e hoʻomaka hou e hana maʻamau.
Nā memo koʻikoʻi: Ua hoʻopau ʻia kēia lāʻau lapaʻau, ʻo Edrophonium, ma kekahi mau ʻāina, e like me ʻAmelika Hui Pū ʻIa. Eia nō naʻe, he mea nui e makaʻala i kēia, no ka mea, aia paha kekahi mau lāʻau lapaʻau ʻē aʻe e hana like ana, a i ʻole e hoʻomaopopo pehea i hoʻohana ʻia ai i ka wā ma mua. Inā he mau nīnau kāu e pili ana i kēia, hiki iā ʻoe ke nīnau i kāu kauka a mea kūʻai lāʻau paha.
ʻO kekahi o nā inoa lama o kēia lāʻau lapaʻau ʻo `(Enlon)`, `(Reversol)`, a me `(Tensilon)`.
He aha kaʻu e haʻi aku ai i ke kauka ma mua o ka lawe ʻana i kēia lāʻau lapaʻau?
Ma mua o ka hāʻawi ʻia ʻana iā ʻoe i ka inikini Edrophonium, e nīnau aku ke kime lapaʻau iā ʻoe i kekahi mau nīnau. Aia kekahi mau mea nui e pono ai ʻoe e ʻike a haʻi iā lākou. E kōkua kēia ʻike iā lākou e hoʻoholo inā kūpono kēia lāʻau lapaʻau iā ʻoe a inā paha ʻoe e pono i ka mālama kūikawā.
Eia kekahi mau mea e like me ia:
- Inā loaʻa iā ʻoe ka hānō .
- Inā he puʻuwai kūpono ʻole kou.
- Inā he ālai ʻōpū kou, ʻo ia hoʻi, he ālai ʻana i loko o nā ʻōpū.
- Inā pilikia ʻoe i ke kahe ʻana o ka mimi .
- Inā ua loaʻa iā ʻoe kahi hopena maʻi a i ʻole kahi hopena maʻamau ʻole i ka edrophonium, sulfites (i loaʻa i kekahi mau meaʻai a me nā lāʻau lapaʻau), nā lāʻau lapaʻau ʻē aʻe, nā meaʻai, nā kala, a i ʻole nā mea mālama.
- Inā ʻoe e hāpai ana a i ʻole e hoʻāʻo ana e hāpai.
- Inā he makuahine hānai waiū ʻoe.
ʻAʻole wale kēia mau mea, akā pono ʻoe e haʻi aku i kāu kauka e pili ana i nā maʻi ʻē aʻe āu e loaʻa nei, a e pili ana i nā lāʻau lapaʻau ʻē aʻe āu e lawe nei (inā paha i kuhikuhi ʻia e ke kauka, kūʻai ʻia mai kahi hale kūʻai lāʻau lapaʻau, a i ʻole nā lāʻau lapaʻau kuʻuna). Mai hūnā i kekahi mea. No ka mea, ʻo kou palekana ka mea nui loa.
Pehea e hāʻawi ʻia ai ʻo Edrophonium?
ʻAʻole kēia he lāʻau lapaʻau hiki iā ʻoe ke lawe ma ka home. He inikini ʻo Edrophonium. Hāʻawi ʻia ia ma ke ʻano he inikini i loko o kahi ʻiʻo a i ʻole he inikini i loko o kahi aa .
Hāʻawi wale ʻia kēia lāʻau pale e kekahi loea mālama ola kino , ma ka haukapila a i ʻole ke keʻena lapaʻau . No laila, ʻaʻohe mea e hopohopo ai. Ua ʻike pono lākou pehea e hāʻawi ai, pehea ka nui e hāʻawi ai, a pēlā aku.
Inā ʻoe e hāʻawi ana i kēia lāʻau lapaʻau i nā keiki ʻōpio, e kamaʻilio me ke kauka pediatric e pili ana i ia mea a e hana pēlā me ke akahele kūikawā.
He aha ka mea e hana ai inā lawe ʻoe i ka nui o ka lāʻau lapaʻau? (Overdosage)
ʻOiai ke hāʻawi ʻia nei kēia e kekahi loea lapaʻau, ua haʻahaʻa loa ka manawa kūpono o ka overdose. Eia nō naʻe, he mea maikaʻi ke makaʻala i nā mea āpau. Inā loaʻa kekahi mea e like me kēia, pono ʻoe e hoʻomaopopo koke i kahi kikowaena kaohi lāʻau make a i ʻole ka lumi pilikia .
E hoʻomanaʻo i hoʻokahi mea hou aʻe: Nou wale nō kēia lāʻau lapaʻau. ʻAʻole ia he manaʻo maikaʻi e hāʻawi i kekahi i kahi lāʻau lapaʻau i kuhikuhi ʻia nou, a i ʻole e lawe i kahi lāʻau lapaʻau i kuhikuhi ʻia no kekahi. He ʻokoʻa ke kino o kēlā me kēia kanaka, no laila e ʻokoʻa paha nā hopena.
He aha inā e hala wau i kahi lāʻau?
ʻOiai ʻaʻole kēia he lāʻau lapaʻau e lawe pinepine ʻia i kēlā me kēia lā ma ka home, ʻaʻole pili ka huaʻōlelo "missing a dose" ma aneʻi. He mea kēia i hāʻawi ʻia ma ka haukapila, ma lalo o ka nānā ʻana a ke kauka, i ka wā e pono ai.
He aha nā pilina ʻē aʻe e hiki ke hana me kēia lāʻau lapaʻau?
Aia kekahi mau lāʻau lapaʻau ʻē aʻe e hiki ke launa pū me ka edrophonium, ʻo ia hoʻi hiki iā lākou ke hoʻopili kekahi i kekahi. ʻO ia ke kumu he mea nui e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau a me nā mea hoʻohui āu e lawe nei.
Eia kekahi mau mea e like me ia:
- ʻO Atropine (he lāʻau lapaʻau kēia e hoʻopilikia i nā mea e like me ka helu o ka puʻuwai)
- ʻO nā lāʻau lapaʻau ʻē aʻe e hoʻoikaika i nā ʻiʻo a hoʻonui paha i kā lākou hana , e like me nā mea i hāʻawi ʻia no nā kūlana e like me ka myasthenia gravis
- Nā mea hoʻomaha ʻiʻo i hoʻohana ʻia i ka wā o kekahi mau ʻoki kino a i ʻole nā hoʻokolohua
- ʻO Quinidine (he lāʻau lapaʻau hoʻi no ka maʻi puʻuwai)
ʻAʻole i piha kēia papa inoa. Aia paha he nui aku. No laila, e hāʻawi i kāu kauka i kahi papa inoa piha o nā lāʻau lapaʻau āpau āu e lawe ai, me nā lāʻau lapaʻau lāʻau, nā lāʻau lapaʻau ʻole i kauoha ʻia, nā huaora, a i ʻole nā mea hoʻohui meaʻai. Eia kekahi, e hōʻoia e haʻi i kāu kauka inā ʻoe e puhipaka, inu waiʻona, a hoʻohana paha i nā lāʻau lapaʻau ʻē aʻe. Hiki i kekahi mau mea ke launa pū me kāu mau lāʻau lapaʻau.
He aha kā mākou e makaʻala ai i ka wā e lawe ai i ka lāʻau lapaʻau?
Ke hāʻawi ʻia kēia inikini Edrophonium iā ʻoe, e nānā pono ʻia kou kūlana e nā limahana lapaʻau. ʻO ia hoʻi, e nānā pono lākou i nā mea e like me kou helu puʻuwai, ka hanu ʻana, a me ke koko. No laila, ʻaʻohe mea e hopohopo ai, aia ʻoe i nā lima palekana.
He aha nā hopena ʻaoʻao e hiki ke loaʻa mai kēia lāʻau lapaʻau?
E like me nā lāʻau lapaʻau āpau, hiki i ka edrophonium ke hana i nā hopena ʻaoʻao i kekahi poʻe. ʻAʻole loaʻa i nā kānaka a pau, akā loaʻa i kekahi poʻe. ʻO kekahi o kēia mau mea nā mea āu e haʻi koke aku ai i kāu kauka , aʻo kekahi ʻaʻole koʻikoʻi a e nalo aku i loko o kekahi mau lā.
Nā hopena ʻaoʻao e pono e hōʻike koke ʻia i ke kauka a i ʻole ke kauka lapaʻau:
Hiki i kēia ke lilo i mea koʻikoʻi iki, no laila inā ʻike ʻoe i kahi mea e like me kēia, pono ʻoe e hōʻike koke iā ia:
- Nā hopena maʻi ʻaleka : ʻŌhūhū ʻili, maneʻo a hives paha, pehu ʻana o ka maka, lehelehe, a i ʻole ke alelo.
- Nā pilikia hanu.
- Nā loli i ka ʻike.
- Ke manaʻo nei i ka nāwaliwali a i ʻole ke poʻo māmā, hāʻule.
- Nā pilikia me ke kaulike, ka kamaʻilio ʻana, ka hele ʻana.
- Nā ʻōʻili.
- Puʻuwai lohi a ʻano ʻē paha.
Nā hopena ʻaoʻao ʻaʻole pono ka ʻōlelo aʻoaʻo lapaʻau (akā pono e hōʻike i ke kauka inā hoʻomau a hoʻopilikia paha):
Nalo pinepine kēia mau mea ma hope o kekahi mau lā, akā inā hoʻomau a hoʻopilikia paha lākou iā ʻoe, e haʻi i kāu kauka .
- Ka maʻi pākī.
- Hoʻonui ʻia ka pono e holo i ka mimi.
- Hoʻonui ʻia ka lawai, ka hou ʻana, nā waimaka.
- Ka ʻūmiʻi ʻana o nā ʻiʻo.
- Ka luaʻi, ka luaʻi.
- Manaʻo luhi a nāwaliwali paha i ʻano ʻē.
ʻAʻole i loko o kēia papa inoa nā hopena ʻaoʻao āpau. Inā ʻike ʻoe i kekahi mea ʻē aʻe i ʻike ʻole ʻia, e nīnau i kāu kauka e pili ana i ia mea.
Ma hea ʻoe e mālama ai i ka lāʻau lapaʻau?
E like me ka mea i ʻōlelo ʻia ma mua, he lāʻau lapaʻau ʻo Edrophonium i hāʻawi ʻia ma ka haukapila a i ʻole ke keʻena lapaʻau. No laila, ʻaʻole ʻoe e ʻae ʻia e lawe i ka home a mālama iā ia. E mālama ʻia ia ma laila ma ka haukapila.
Leka Hoʻihoʻi Hope Loa
ʻAe, ua kamaʻilio nui mākou e pili ana iā Edrophonium. Eia kekahi mau mea e hoʻomanaʻo ai:
- He ʻōʻō ʻo Edrophonium i hoʻohana nui ʻia no ka ʻike ʻana i kahi maʻi i kapa ʻia ʻo myasthenia gravis a e ʻike pehea e pane ai kou kino i kāna lāʻau lapaʻau. Kōkua nō hoʻi ia i ka hoʻohuli koke ʻana i nā hopena o nā mea hoʻomaha ʻiʻo ma hope o ke ʻoki ʻana.
- He lāʻau lapaʻau kēia i hāʻawi wale ʻia e kekahi loea lapaʻau ma ka haukapila a i ʻole ke keʻena lapaʻau.
- Ma mua o ka lawe ʻana i kēia lāʻau lapaʻau, e haʻi pono i kāu kauka e pili ana i nā maʻi ʻē aʻe āu e loaʻa nei, nā maʻi allergies, a me nā lāʻau lapaʻau ʻē aʻe āu e lawe nei .
- E like me nā lāʻau lapaʻau āpau, hiki i kēia ke loaʻa nā hopena ʻaoʻao. Inā ʻike ʻoe i kekahi mau mea koʻikoʻi, e haʻi koke i kāu kauka . E makaʻala hoʻi i nā mea ʻē aʻe.
- Inā he mau nīnau a hopohopo paha kāu e pili ana i kēia lāʻau lapaʻau, mai kānalua e nīnau i kāu kauka, kauka lāʻau, a i ʻole kekahi mea lawelawe olakino ʻē aʻe. Aia lākou ma laila e kōkua iā ʻoe.
E hoʻomanaʻo, no ka ʻike laulā wale nō kēia ʻatikala. ʻAʻole pono e lawe ʻia ma ke ʻano he ʻōlelo aʻoaʻo lapaʻau. E kūkākūkā mau me ke kauka i ka wā e hoʻoholo ai e pili ana i kou olakino.
👩🏽⚕️ Nā nīnau hou aku (FAQs)
💬 He aha ke ʻano o ka maʻi e lapaʻau ʻia ai ʻo Efavirenz (Efavirenz / Sustiva)?
He lāʻau koʻikoʻi loa kēia a he mana (NNRTI) i hāʻawi ʻia i nā poʻe maʻi 'HIV / AIDS'! ʻAʻole lawe wale ʻia kēia, lawe ʻia me ka hui pū ʻana me 2 mau lāʻau HIV ʻē aʻe (ART therapy). ʻO ka hana a kēia lāʻau, ʻo ia ke kāohi loa i ka laha ʻana a me ka ulu ʻana o ka maʻi HIV i loko o ke kino (pepehi i ka maʻi), a hoʻonui i ka pale ʻana o ka mea maʻi (CD4 Count).
💬 Pehea lā e kāohi ai kēia lāʻau lapaʻau (Efavirenz) i ka maʻi HIV?
Ke komo ka maʻi HIV i loko o kou koko, holo kahi 'mīkini' kūikawā (Reverse transcriptase) i loko o ka maʻi e hoʻololi i kāna RNA i loko o ka DNA o ko kākou kino. ʻO ka hana a kēia lāʻau Efavirenz, ʻo ia ke hele pololei i kahi huila o kēlā mīkini a hoʻopaʻa iā ia (Lock down/Inhibit)! A laila, ʻaʻole hiki i ka maʻi ke hana hou a paʻa i laila.
💬 No ke aha i loaʻa ai iaʻu nā moeʻuhane ma hope o ka lawe ʻana i kēia pila?
ʻO ia ka hopena kaulana loa a me ka hopena nui loa o kēia lāʻau lapaʻau (nā hopena o ka ʻōnaehana nerve waena)! Ke hele kēia lāʻau lapaʻau i ka lolo, ʻike ka mea maʻi i nā hallucinations, ka poniuniu, nā moeʻuhane ʻino a me ke kaumaha koke. (He pinepine ka hala ʻana o 2-4 mau pule). ʻO ia ke kumu e ʻōlelo ai nā kauka e 'lawe i kēia i ka wā moe a ma ka ʻōpū ʻole no ka mea ʻoi aku ka ʻino o kēia mau hopena ʻaoʻao inā ʻai ʻoe i nā meaʻai ʻaila/momona ma ka papaʻaina'!
ʻEdrophonium , ʻEdrophonium, Myasthenia Gravis, Myasthenia Gravis, Nāwaliwali o nā ʻiʻo, ʻŌnaehana aʻalolo, Nā hopena ʻaoʻao o nā lāʻau lapaʻau, Nā pilina me nā lāʻau lapaʻau
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