He aha ʻo Gastrin? Hoʻopilikia anei ia i kou mau pilikia ʻōpū?

Ua noʻonoʻo paha ʻoe i ka nui o nā mea e hana nei i loko o ko kākou kino, ʻoiai ma hope o kā kākou ʻai ʻana? Loaʻa iā kākou kahi hui o nā ʻelele kemika liʻiliʻi i loko o ko kākou kino e kōkua ana i kēia mau mea āpau. Kāhea mākou i kēia mau hormones. I kēia lā e kamaʻilio mākou e pili ana i kekahi hormone kūikawā. ʻO ia hoʻi ʻo gastrin. He mea nui loa kēia gastrin no ka hana ʻana o kā mākou ʻōnaehana hoʻoheheʻe.

He aha ka hana a Gastrin?

ʻAe, e nānā kākou i ka hana a kēia hoaaloha i kapa ʻia ʻo Gastrin no ko kākou kino. He nui kāna mau hana nui.

• Ka hana ʻana o ka waikawa o ka ʻōpū: ʻO ka mea nui loa, ʻo ia ke haʻi aku i kou ʻōpū e hoʻokuʻu i ka waikawa gastric. ʻO kēia waikawa gastric ka mea a mākou e kapa nei he waikawa hydrochloric. Me ka ʻole o kēia, he mea paʻakikī loa ka hoʻoheheʻe ʻana i ka meaʻai.
• Hana ʻiʻo o ka ʻōpū: Kōkua pū ʻo Gastrin i nā ʻiʻo i loko o kou ʻōpū e hana pono, ʻo ia hoʻi ke kumu o ka neʻe ʻana o ka gastric, kahi e kōkua ai i ka hoʻohuihui a me ka wāwahi ʻana i ka meaʻai.
• Hoʻoulu hou i ka paia o ka ʻōpū: Pono e hoʻoulu hou mau ʻia ka uhi palupalu o ko kākou ʻōpū, ʻo ia hoʻi ka mucosa. Kōkua pū ʻo Gastrin i kēia.
• Ka hoʻoulu ʻana o ka gallbladder a me ka pancreas: ʻO Gastrin, me kekahi hormone i kapa ʻia ʻo cholecystokinin, kōkua i kāu gallbladder a me ka pancreas e ʻaelike a hoʻokuʻu i nā wai ʻai.

He aha ka ʻokoʻa ma waena o Gastrin a me ka waikawa Gastric?

He mea huikau iki anei kēia? I ka ʻōlelo maʻalahi, penei. He hormone ʻo Gastrin. Ua like ia me kahi leka. Ke haʻi aku nei kēia leka i ka ʻōpū, "ʻAe, e hoʻokuʻu i ka waikawa gastric." A laila hoʻāla kēia waikawa gastric i ka enzyme digestive pepsin. I ka hui pū ʻana, hana kēia mau mea ʻelua i ka wai gastric i loko o ko kākou ʻōpū. Maopopo iā ʻoe?

Ma hea kahi i hana ʻia ai ʻo gastrin?

Hoʻopuka nui ʻia ʻo Gastrin e nā ʻōpū o kā mākou ʻōnaehana hoʻoheheʻe. Loaʻa kēia hormone mai kahi ʻano cell kūikawā i kapa ʻia ʻo G-cells. ʻO ka leka "G" ke kū nei no "gastrin."

ʻO ka hapa nui o ka gastrin mai kou ʻōpū mai , ʻoiai ka ʻāpana haʻahaʻa o kou ʻōpū (kapa mākou iā ia he antrum). Aia kēia mau G-cell i loko o nā kelepa gastric ma ka paia o kou ʻōpū. Eia kekahi, hana ʻia kekahi gastrin e ka duodenum, ka ʻāpana mua o kou ʻōpū liʻiliʻi, a e ka pancreas.

He aha nā mea e hoʻopilikia ai i ka hoʻokuʻu ʻana o gastrin?

He mea kupaianaha ke ʻano o ka hoʻokuʻu ʻia ʻana o ka gastrin ke noʻonoʻo ʻoe e pili ana i ka ʻai ʻana! Pehea ʻoe i ʻike ai i kēlā? Hoʻopili mau ʻia ko mākou lolo a me ka ʻōnaehana hoʻoheheʻe ma o kahi pūnaewele kūikawā o nā aʻalolo i kapa ʻia ʻo nā aʻalolo vagal. Hele ka ʻike i mua a i hope ma o kēia mau aʻalolo.

No laila, ke noʻonoʻo ʻoe e pili ana i ka meaʻai, hoʻouna nā aʻalolo vagal i loko o kou lolo i kahi leka i ka ʻōpū, e ʻōlelo ana, "ʻAe, e hiki mai ana ka meaʻai, e hoʻokuʻu i ka gastrin a e mākaukau no ka ʻai ʻana." A laila, ke hoʻomaka ʻoe e ʻai, ʻike nā aʻalolo i loko o kou ʻōpū ua komo ka meaʻai a hoʻokuʻu i nā gastrin hou aku.

Nā mea ʻē aʻe e hoʻoulu ai i ka hoʻokuʻu ʻana o gastrin:

• ʻO ka piʻi ʻana o ka pH o ka ʻōpū (ʻo ia hoʻi, ke emi ka acidity).
• Huki ʻia nā paia o ka ʻōpū ke komo ka meaʻai.
• ʻO kekahi mau meaʻai , ʻoiai nā mea i loaʻa ka protein, e komo i loko o ka ʻōpū.

Hoʻokuʻu ʻo Gastrin i ka waikawa gastric, ka mea e hoʻoulu ai i ka pepsin. I ka hui pū ʻana, wāwahi kēia mau mea a hoʻoheheʻe i nā protein i loko o ka ʻōpū. Hoʻoulu pū ʻo Gastrin i ka neʻe ʻana o nā ʻiʻo i loko o ka ʻōpū.

Pehea e hoʻōki ai i ka hoʻokuʻu ʻana o gastrin?

I ka wā e hemo ai ka meaʻai mai kou ʻōpū a neʻe i loko o ka ʻāpana mua o ka ʻōpū liʻiliʻi, ʻo ia hoʻi ka duodenum, hoʻomaka ka pae aʻe o ka ʻai ʻana. ʻO ia ka manawa e hoʻomaka ai ka emi ʻana o ka hoʻokuʻu ʻana o ka gastrin. I ka wā e haʻalele ai ka meaʻai mai ka ʻōpū a piʻi aʻe ka nui o ka waikawa o ka ʻōpū, emi iho ka gastrin.

Ke komo ka meaʻai i loko o ka duodenum, hoʻokuʻu kou gallbladder a me ka pancreas i ko lākou wai hoʻoheheʻe. A laila, hoʻokuʻu kā mākou ʻōnaehana hoʻoheheʻe i kahi hormone ʻē aʻe i kapa ʻia ʻo somatostatin. Hoʻopau kēia somatostatin i nā hormones ʻē aʻe (e like me gastrin). Ua like ia me ka hoʻopau ʻana i kahi kuapo.

Pehea e nānā ai i nā pae o ka gastrin?

Aia kekahi hoʻāʻo koko kūikawā e nānā i kou pae gastrin. Kāhea mākou ia he hoʻāʻo gastrin. ʻO kahi mea mālama ola kino, e like me ke kauka a kahu maʻi paha, e lawe i kahi hāpana koko liʻiliʻi mai kahi aʻa koko ma kou lima a hoʻouna aku i kahi lab no ka hoʻāʻo ʻana.

No ke aha he mea nui koʻu pae gastrin?

Nānā nā kauka i kāu mau pae gastrin e ʻike inā kiʻekiʻe loa lākou. He mea kākaʻikahi nā pae gastrin haʻahaʻa, akā hiki i nā pae gastrin kiʻekiʻe ke hōʻike i kekahi mau maʻi a me nā kūlana gastrointestinal.

He aha ka manaʻo o ka hoʻonui ʻia ʻana o ka gastrin (Hypergastrinemia)?

Ke kiʻekiʻe ka pae o ka gastrin, kapa mākou ia he hypergastrinemia. I kekahi manawa, hiki i ka hypergastrinemia ke ʻano he mau puʻupuʻu e hana ana i ka gastrin i loko o kou kino, i kapa ʻia ʻo gastrinomas. Hiki i kēia mau mea ke hana i loko o kou pancreas a i ʻole duodenum.

I kekahi manawa, hiki i ka hypergastrinemia ke ʻano he mea i loko o kou ʻōpū e pale ana iā ia mai ka hana ʻana i ka waikawa gastric. Ke emi ka waikawa o ka ʻōpū, hoʻokuʻu ʻia ka gastrin hou aku. Eia kekahi, ua hoʻopilikia ʻia nā hōʻailona e hoʻōki maʻamau i ka hana ʻana o gastrin.

He aha ka mea e hana ai inā piʻi aʻe ka nui o ka gastrin?

Inā kiʻekiʻe kou pae gastrin, hiki i ka nui o ka waikawa gastric i loko o kou ʻōpū a me ka duodenum ke lilo i kiʻekiʻe loa. Hiki i ka nui o ka waikawa ke hōʻino i ka uhi pale palupalu o kou ʻōpū a me ka duodenum, e hana ana i nā ʻōpū, i ʻike ʻia hoʻi he maʻi ʻōpū peptic.

Eia kekahi, ʻo ka nui o ka waikawa o ka ʻōpū hiki ke hana i kahi maʻi i kapa ʻia ʻo GERD (Gastroesophageal Reflux Disease), ʻo ia hoʻi kahi maʻi lōʻihi e piʻi ai ka waikawa i loko o ka puʻu. Inā loaʻa iā ʻoe ka maʻi ʻōpū peptic a i ʻole GERD a ʻaʻole ia e hoʻomaikaʻi me ka lāʻau lapaʻau, e nānā paha kāu kauka i kāu pae gastrin.

He aha nā kūlana olakino e pili ana me ke kiʻekiʻe o ka gastrin?

Inā loaʻa iā ʻoe nā gastrinomas, hiki ke kiʻekiʻe aʻe kou pae gastrin a me ka waikawa gastric. ʻO Gastrinomas kahi ʻano o ka pancreatic neuroendocrine tumor (PET) e hūnā ana i ka gastrin. Hiki iā lākou ke maʻi kanesa a ʻaʻole paha.

Nā kūlana e hoʻoulu ai i nā gastrinomas:

• ʻO ka maʻi Zollinger-Ellison.
• ʻO ka neoplasia endocrine lehulehu ʻano 1 (MEN1).

Nā kūlana i hoʻokiʻekiʻe ʻia ai ka gastrin a me ka waikawa gastric me ka ʻole o nā gastrinomas:

• Ka hāʻule mau ʻana o ka puʻupaʻa.
• Ka ālai ʻana o ka puka ʻōpū (GOO).

Inā haʻahaʻa kāu hana ʻakika gastric, loaʻa paha iā ʻoe nā pae gastrin kiʻekiʻe akā haʻahaʻa nā pae waikawa gastric. Hiki paha kēia ma muli o ka gastritis atrophic, ʻo ia ke ʻano i luku ʻia ai nā cell e hana ana i ka waikawa ʻōpū.

ʻO nā kumu nui o ka gastritis atrophic:

• ka maʻi H. pylori.
• Nā maʻi Autoimmune (e.g. autoimmune atrophic gastritis).

ʻO nā kumu ʻē aʻe o ka emi ʻana o ka hana ʻana o ka waikawa gastric:

• Nā lāʻau pale waikawa, e like me nā mea pale H2 a i ʻole nā ​​mea pale pamu proton (PPI).
• ʻO ka Vagotomy (ka wehe ʻoki ʻana a i ʻole ka ʻoki ʻana i ke aʻalolo vagal).

He aha kaʻu e hana ai inā loaʻa iaʻu nā hōʻailona o ke kiʻekiʻe o ka gastrin?

Inā loaʻa iā ʻoe nā hōʻailona o ka ʻōpū, ʻoiai inā pinepine lākou a i ʻole ua loaʻa no ka manawa lōʻihi, he mea nui e ʻike i ke kauka. Eia kekahi mau hōʻailona e pili ana paha me ka hoʻonui ʻia o ka gastrin:

• ʻEha a ʻūlū paha ka ʻōpū.
• ʻEha mau ka umauma a me ka ʻōpū ʻole.
• ʻO ka reflux waikawa a i ʻole ka meaʻai e paʻa ana i ka puʻu.
• ʻEha mau ka ʻāʻī a me ka leo honi.
• Ka maʻi pākī mau.
• Nā pilikia hoʻoheheʻe ʻana.

Hiki i kēia mau hōʻailona ke hōʻike he kiʻekiʻe kou pae o ka waikawa gastric, a i ʻole he atrophic gastritis kou, maʻi peptic ulcer, a i ʻole GERD. Pili paha kēia a ʻaʻole paha i ka gastrin. Eia nō naʻe, he mea nui e ʻike pono a mālama i kēia mau kūlana.

E hoʻomanaʻo, inā loaʻa iā ʻoe nā hōʻailona e like me kēia, mai ho'āʻo e nānā iā ʻoe iho ma ka nānā ʻana i ka ʻike ma ka pūnaewele. ʻOi aku ka maikaʻi o ke ʻike ʻana i ke kauka a loaʻa ka ʻōlelo aʻoaʻo.

Leka Lawe-Home

ʻAe, e nānā kākou i kekahi mau mea maʻalahi e hoʻomanaʻo e pili ana i ka gastrin a mākou i kamaʻilio ai.

• He hormone koʻikoʻi ʻo Gastrin i kā mākou ʻōnaehana hoʻoheheʻe .
• ʻO kāna hana nui, ʻo ia ke haʻi aku i ka ʻōpū e hoʻokuʻu i ka waikawa gastric .
• Inā kiʻekiʻe loa a haʻahaʻa paha ka waikawa o kou ʻōpū , pili paha ia i ka gastrin.
• Inā loaʻa iā ʻoe kekahi mau hōʻailona ʻōpū, a i ʻole nā ​​​​kūlana i hoʻomaikaʻi ʻole ʻia me ka mālama ʻana, hiki i ke kauka ke hoʻāʻo i kāu mau pae gastrin.
• Hiki i nā pae gastrin kiʻekiʻe ke hōʻailona i kahi maʻi, no laila he mea nui e ʻimi i ke aʻo lapaʻau inā loaʻa iā ʻoe nā hōʻailona.

No laila, he mea liʻiliʻi akā ikaika ʻo Gastrin e hana mālie ana i loko o ko kākou kino. ʻO ka ʻike ʻana i kēia he mea nui loa ia no kou olakino. Inā he mau nīnau hou aku kāu, mai kānalua e nīnau i kāu kauka.

ʻO Gastrin, hormones, digestion, acid ʻōpū, peptic ulcer, GERD, hypergastrinemia