Pono anei mākou e aʻo e pili ana i nā H2 Blockers no kou ʻeha puʻuwai a me ka gastritis?

Ke manaʻo nei ʻoe i kekahi manawa i ka piʻi ʻana o ka waikawa o ka ʻōpū, ka ʻeha puʻuwai, a i ʻole ka ʻeha ʻōpū ma hope o ka ʻai ʻana? A i ʻole he maʻi koʻikoʻi kou e like me ka gastritis? A laila ua lohe paha ʻoe i kahi ʻano lāʻau i kapa ʻia ʻo H2 blockers. I kēia lā, e kamaʻilio kākou e pili ana i ke ʻano o kēia mau mea pale H2, pehea lākou e hana ai, a ma nā kūlana hea lākou e hoʻohana ʻia ai.

He aha nā mea pale H2 (nā mea pale H2)?

I ka ʻōlelo maʻalahi, ʻo nā mea pale H2 he ʻano lāʻau lapaʻau e hōʻemi ana i ka nui o ka waikawa i hana ʻia i loko o kou ʻōpū. I kēia manawa ke noʻonoʻo nei paha ʻoe i ke kumu o ka waikawa ʻōpū. He mea nui ka waikawa ʻōpū no ka ʻeli ʻana i ka meaʻai a mākou e ʻai ai. Eia naʻe, hoʻomaka nā pilikia ke nui loa kēia waikawa. A laila hiki ke hōʻino ʻia nā ʻiʻo palupalu o kā mākou ʻōnaehana ʻai (GI - gastrointestinal tract). ʻO ia ke kumu e kū mai ai nā hōʻailona e like me ka ʻeha o ka ʻōpū a me ka heartburn. I kekahi manawa, hiki ke paʻakikī ka ʻai ʻana i ka meaʻai ʻala a hiki iā ʻoe ke noʻonoʻo, "Auē, no ke aha wau i ʻai ai i kēlā?"

No laila, inā ʻoe kekahi e ʻeha nei i nā hōʻailona i hoʻoulu ʻia e ka hoʻonui ʻia o ka waikawa o ka ʻōpū, makemake paha ʻoe e noʻonoʻo e hoʻohana i kahi mea pale H2.

He aha nā kūlana i mālama ʻia me nā mea pale H2?

Hoʻohana nui ʻia nā mea pale H2 e mālama i nā kūlana e pili ana i ka hana nui ʻana o ka waikawa o ka ʻōpū. Akā hoʻokahi mea e hoʻomanaʻo ai: Me ka hoʻomau ʻana o ka hoʻohana ʻana i kēia mau lāʻau lapaʻau, hiki ke emi mālie ko lākou pono i ka hala ʻana o ka manawa.

Inā loaʻa iā ʻoe kahi maʻi mau loa e pili ana i ka nui o ka waikawa ʻōpū, makemake paha ʻoe e noʻonoʻo i kahi ʻano lāʻau i kapa ʻia he proton pump inhibitor (PPI) . ʻOiai ʻaʻole hana wikiwiki nā PPI e like me nā mea pale H2, hōʻemi pū lākou i ka hana ʻana o ka waikawa ʻōpū a hiki ke hoʻohana ʻia no nā manawa lōʻihi ma mua o nā mea pale H2. ʻO nā PPI kahi ʻano lāʻau i ʻoi aku ka ikaika i ka kaohi ʻana i ka waikawa ma mua o nā mea pale H2.

E nānā kākou i kekahi o nā kūlana nui i mālama ʻia me nā mea pale H2:

Nā ʻōpū ʻōpū a me nā ʻōpū duodenal

Ke piʻi nui ka waikawa o ka ʻōpū, hiki iā ia ke ʻinoʻino i ka uhi o ka ʻōpū a hoʻoulu i nā ʻōpū. Hoʻemi nā mea pale H2 i ka hana ʻana o ka waikawa o ka ʻōpū, e hāʻawi ana i kēia mau ʻōpū i ka manawa e ho'ōla ai.

Eia kekahi, hiki i ka waikawa o ka ʻōpū ke hele i luna i ka ʻāpana mua o ko mākou ʻōpū liʻiliʻi (duodenum) a hoʻoulu i nā ʻeha ma laila. Kāhea mākou i kēia mau ʻeha duodenal . ʻOiai ʻo PPI ka lāʻau lapaʻau kūpono loa no kēia, hiki i nā mea pale H2 ke mālama i kēia ʻano. Ua ʻae ka US Food and Drug Administration (FDA) i nā mea pale H2 no ka mālama mālama pōkole e pale aku i nā ʻeha hou mai ka hoʻokumu ʻana. Hiki i kāu kauka ke kamaʻilio me ʻoe e pili ana i ka mālama kūpono a me ke ʻano mālama nou.

ʻO ka reflux waikawa a me ka GERD

He pilikia kēia i loaʻa i nā poʻe he nui. ʻO ka reflux waikawaʻO ia hoʻi, piʻi hou mai ka waikawa i loko o ka ʻōpū, ʻo ia hoʻi, piʻi aʻe, a komo i loko o ka puʻu ma o ko kākou esophagus (paipu meaʻai). ʻO kēia ke kumu o ka heartburn. Inā hoʻomau kēia ʻano, hiki nō hoʻi ke loaʻa ka mumū o ka esophagus (esophagitis). Hiki i kahi mea pale H2 ke hāʻawi i ka hōʻoluʻolu no ka reflux acid i kekahi manawa. Akā inā loaʻa iā ʻoe kahi ʻano reflux acid lōʻihi, ʻo ia hoʻi, GERD (Gastroesophageal Reflux Disease) , ʻoi aku ka maikaʻi o ka hoʻohana ʻana i ka PPI.

ʻO ka maʻi Zollinger-Ellison

He kūlana kākaʻikahi loa kēia. Hana ʻia ia i ka wā e hana ai kekahi mau puʻupuʻu i loko o ko kākou kino i ko kākou ʻōpū e hana i ka nui o ka waikawa. Hiki i nā mea pale H2 ke kōkua ma ka pale ʻana i ka hana ʻana o ka waikawa ʻōpū. Eia nō naʻe, i kēia hihia, e kuhikuhi paha kāu kauka i kahi PPI.

Ua hōʻoluʻolu ʻia nā hōʻailona e nā mea pale H2

Hiki i kēia mau lāʻau lapaʻau ke hōʻoluʻolu i nā hōʻailona ma lalo nei:

• ʻŌhū, ʻai ʻole
• ʻEha ʻōpū
• ʻO ka ʻāʻī a me ka reflux
• Ka luaʻi a me ka luaʻi
• ʻŌpū ʻawaʻawa, ʻono ʻawaʻawa i ka puʻu

Pehea e hana ai nā mea pale H2?

ʻO kekahi inoa no nā mea pale H2 ʻo ia nā histamine-2 (H2) antagonists . Hāʻawi kēia inoa iā mākou i kahi manaʻo iki pehea e hana ai kēia mau lāʻau. Ua aʻo paha ʻoe e pili ana i ke kuleana o kahi 'antagonist' ma ka papa Pelekania i kou wā ma ke kula. Ma kahi ʻōlelo, ʻo ka antagonist kahi mea e hoʻopilikia ai. Ma ke ʻano like, pale nā ​​​​​​antagonists H2 i ka hana ʻana o ka waikawa o ka ʻōpū.

E noʻonoʻo i kēia ʻano. Ma hope o kou ʻai ʻana i ka ʻai, hoʻokuʻu kou kino i kahi kemika i kapa ʻia ʻo H2. Hele kēia H2 a hoʻopili i nā wahi kikoʻī (nā mea loaʻa H2) ma nā pūnaewele i loko o nā paia o kou ʻōpū. ʻO kēia hoʻopili ʻana ke kumu e hoʻokuʻu ai kou ʻōpū i ka waikawa.

Ke lawe ʻoe i kahi antagonist H2, a i ʻole ka mea pale H2, hele ka lāʻau i kēlā mau mea loaʻa H2 ma mua o ka hiki ʻana o H2 ke hoʻopaʻa iā lākou. I ka ʻōlelo maʻalahi, "ālai" nā mea pale H2 iā H2 mai ka hoʻopaʻa ʻana i kēlā mau mea loaʻa. Hoʻemi kēia i ka hana ʻana o ka waikawa i loko o ka ʻōpū.

ʻAʻole kēia e hoʻopilikia i kāu kaʻina hana hoʻoheheʻe. Akā e hōʻemi ia i ka nui o ka waikawa keu e hoʻoulu ai i kēlā mau hōʻailona ʻeha. Ua maopopo iaʻu?

He aha nā ʻano o nā mea pale H2? (Nā lāʻau lapaʻau i loaʻa ma ka mākeke)

Aia kekahi mau ʻano o nā mea pale H2. Hiki iā ʻoe ke kūʻai i kekahi ma luna o ke kūʻai aku (OTC) ma kahi hale kūʻai lāʻau me ka ʻole o ke kauoha (Rx). Pono kekahi i ke kauoha mai ke kauka. ʻOkoʻa kēia ma muli o ke ʻano o ka lāʻau a me ka nui o ka lāʻau.

ʻO nā ʻano o nā mea pale H2 i loaʻa i kēia manawa:

• ʻO Cimetidine ( inoa inoa, no ka laʻana, Tagamet®) - Loaʻa kēia ma OTC a me Rx.
• ʻO Famotidine(Inoa inoa, no ka laʻana, Pepcid®) - Loaʻa pū kēia ma OTC a me Rx.
• ʻO Nizatidine (inoa inoa ʻo Axid®, no ka laʻana) - Hiki ke loaʻa kēia me kahi Rx wale nō.

Ua lohe paha ʻoe iā Ranitidine ( i ʻike ʻia ma ka inoa inoa ʻo Zantac®). ʻO ia ka mea pale H2 mua i ʻāpono ʻia e ka FDA i ka makahiki 1983. Eia nō naʻe, i ʻApelila 2020, ua kauoha ka FDA i nā mea hana e wehe iā Ranitidine mai ka mākeke. ʻO ke kumu o kēia, ua ʻike nā hoʻokolohua FDA i ka wā i mālama ʻia ai ʻo Ranitidine no ka manawa lōʻihi, ua piʻi aʻe nā pae o kahi carcinogen hiki (nitrosodimethylamine, a i ʻole NDMA) i nā pae palekana ʻole. Ua ʻike pū nā kānaka noiʻi ua piʻi aʻe nā pae NDMA i ka wā i mālama ʻia ai ʻo Ranitidine ma nā mahana kiʻekiʻe.

Pehea e hoʻohana ai i kēia lāʻau lapaʻau?

Loaʻa ka hapa nui o nā mea pale H2 ma ke ʻano o nā pila a i ʻole nā ​​capsules āu e lawe ai ma ka waha. I kekahi manawa hele mai lākou i loko o ka pauka hiki iā ʻoe ke hoʻohui me ka wai a inu no ka poʻe pilikia i ka ale ʻana i nā pila.

Hiki ke hāʻawi ʻia kekahi mau mea pale H2 ma ke kino (IV) , ʻoiai inā ʻoe e mālama ʻia ana i ka haukapila a ʻaʻole hiki ke lawe i ka lāʻau lapaʻau ma ka waha.

ʻO ka manawa hea ka maikaʻi loa e lawe ai i kahi H2 blocker?

Inā ʻike ʻoe e ʻai ana ʻoe i kahi mea āu e makemake ʻole ai, e like me ka meaʻai ʻala, he manaʻo maikaʻi ia e lawe i kahi mea pale H2 ma kahi o 30 a 60 mau minuke ma mua o kou ʻai ʻana. Ma kēlā ʻano, loaʻa i ka lāʻau ka manawa e hoʻomaka ai e hana. He mea maikaʻi ke lawe iā ia ma hope o kou pau ʻana i ka ʻai ʻana, akā hiki ke hala a hiki i hoʻokahi hola no ka emi ʻana o kāu mau hōʻailona.

Ma ke ʻano he lāʻau lapaʻau pōkole no kahi maʻi e like me ka ʻōpū ʻōpū, hiki i kāu kauka ke haʻi iā ʻoe e lawe i kēia lāʻau lapaʻau penei:

• I hoʻokahi manawa i ka lā, ma mua o ka moe ʻana i ka pō.
• A i ʻole hoʻokahi manawa i ke kakahiaka a hoʻokahi manawa i ka pō.

ʻO ka mea nui loa, inā pono ʻoe e hoʻohana i kahi mea pale H2 no nā pule ʻelua a ʻoi aku e kāohi i kāu mau hōʻailona, ​​​​pono ʻoe e ʻike i ke kauka. ʻAʻole ia he manaʻo maikaʻi e hilinaʻi i nā mea pale H2 no ka manawa lōʻihi me ka ʻole o ke kamaʻilio ʻana me ke kauka.

Pehea ka lōʻihi o ka hana ʻana o nā mea pale H2? Pehea kona ʻokoʻa mai nā lāʻau lapaʻau ʻē aʻe?

ʻO ka maʻamau, ma kahi o hoʻokahi hola e manaʻo ai i ka hōʻoluʻolu mai nā hōʻailona ma hope o ka lawe ʻana i kahi mea pale H2. ʻO ka maʻamau, mau nā hopena mai ʻehā a ʻumi hola . ʻO kēia hana wikiwiki e lilo ia i koho maikaʻi inā makemake ʻoe i ka hōʻoluʻolu koke a i ʻole inā loaʻa wale iā ʻoe ka ʻeha puʻuwai i kekahi manawa.

Inā makemake ʻoe i ka hōʻoluʻolu wikiwiki, hiki iā ʻoe ke hoʻāʻo i kahi antacid . Hoʻopau nā antacids i ka waikawa i loko o kou ʻōpū. E hoʻomaka lākou e hana wikiwiki ma mua o kahi mea pale H2, akā ʻaʻole e mau ko lākou hopena e like me ka mea pale H2.

Inā lōʻihi kou mau hōʻailona, ​​ʻoiai inā ʻaʻole lawa ka hōʻoluʻolu o ka mea pale H2, pono paha ʻoe e lawe i ka PPI. Hiki i ka PPI ke hala i hoʻokahi a ʻehā mau lā e hoʻopau piha ai, akā ʻoi aku ka lōʻihi o kona mau hopena ma mua o ka mea pale H2.

Loaʻa iā ʻoe nā hopena ʻaoʻao o nā mea pale H2?

Hāʻawi nā mea pale H2 i ka hōʻoluʻolu me ka haʻahaʻa o ka pilikia o nā hopena ʻaoʻao. Eia nō naʻe, e like me nā lāʻau lapaʻau āpau, hiki ke loaʻa nā hopena ʻaoʻao liʻiliʻi.

Nā hopena ʻaoʻao maʻamau

• ʻEha ʻōpū
• ʻEha ʻiʻo
• Ka paʻa ʻana o ka ʻōpū
• Ka maʻi kahe (pehu ʻana)
• Waha maloʻo
• Luhi
• ʻEha poʻo

Nā mea e makaʻala nui ai

ʻOiai he mea kakaikahi loa, hiki i nā mea pale H2 ke hana i nā hōʻailona neurological (e laʻa me ka huikau, ka ʻōlelo slurred) i kekahi mau hui pilikia kiʻekiʻe. ʻOi aku ka nui o kou ʻike ʻana i kēia mau hōʻailona inā ʻoi aku ʻoe ma mua o 50 a ua emi ka hana o nā puʻupaʻa a i ʻole ke akepaʻa . Eia nō naʻe, nalo pinepine kēia mau hōʻailona i loko o kekahi mau lā ma hope o ka hoʻōki ʻana i ka lāʻau lapaʻau.

Hiki paha nā pilikia me nā lāʻau lapaʻau ʻē aʻe?

Hiki i kekahi mau mea pale H2 (no ka laʻana, cimetidine) ke pale i kekahi mau lāʻau lapaʻau ʻē aʻe āu e lawe nei mai ka hana pono ʻana. No ka laʻana, hiki i ka cimetidine ke hōʻemi i ka pono o kekahi mau SSRI (kahi ʻano lāʻau lapaʻau i hoʻohana ʻia e mālama i nā maʻi noʻonoʻo e like me ke kaumaha) a me ka warfarin (kahi lāʻau lapaʻau e pale ai i nā ʻōpū koko).

No laila, ma mua o ka hoʻomaka ʻana i kahi lāʻau lapaʻau hou, he mea nui loa e kamaʻilio me kāu kauka e ʻike ai inā he mau pilina maikaʻi ʻole me nā lāʻau lapaʻau āu e lawe nei.

He palekana anei ka hoʻohana ʻana i nā mea pale H2 i ka wā hāpai a me ka hānai waiū?

Pono nā noiʻi hou aku e hoʻoholo ai i ka palekana o ka hoʻohana ʻana i nā mea pale H2 i ka wā hāpai, akā ua ʻike nā kānaka noiʻi e hele ka lāʻau i loko o ka waiū umauma .

Inā ʻoe e lawe ana i kahi mea pale H2 a hāpai, e kamaʻilio me kāu kauka. E nīnau iā ia inā palekana ke lawe ʻana i kēia lāʻau i ka wā hāpai a i ka wā e hānai waiū ana paha.

Āhea ʻoe e pono ai e ʻike i ke kauka?

E like me kā mākou i ʻōlelo ai ma mua, inā pono ʻoe e hoʻohana i nā mea pale H2 no nā pule ʻelua a ʻoi aku e kāohi i kāu mau hōʻailona, ​​​​pono ʻoe e ʻike i ke kauka. He mea nui e ʻike pono i ke kumu o kāu mau hōʻailona. Pono paha ʻoe i kahi hopena lōʻihi, e like me ka PPI.

Eia kekahi, e haʻi i kāu kauka inā loaʻa iā ʻoe kekahi mau hopena maikaʻi ʻole i ka lāʻau lapaʻau a ʻike paha i kekahi mau hopena ʻaoʻao. Pono paha e hoʻololi ʻia kāu dosage a i ʻole pono paha ʻoe e hoʻololi i kahi lāʻau lapaʻau ʻē aʻe.

He aha ka mea pale H2 palekana loa? He aha ka mea maikaʻi loa no GERD?

Ua like like nā mea pale H2 i ʻāpono ʻia e ka FDA ma ke ʻano o ko lākou palekana a me ka pono.

Eia nō naʻe, inā ʻoe e lawe ana i nā lāʻau lapaʻau ʻē aʻe a ke noʻonoʻo nei e hoʻohana i kahi mea pale H2, ʻoi aku ka maikaʻi o ke kamaʻilio ʻana me kāu kauka. He mea nui e koho i kahi lāʻau lapaʻau e ʻole e hoʻopilikia i ka pono o nā lāʻau lapaʻau āu e lawe nei.

No GERD, hiki i kekahi mea pale H2 ke kōkua i ka hōʻoluʻolu ʻana i nā hōʻailona reflux acid. Eia nō naʻe, inā he maʻi mau kou reflux acid (e like me GERD), ʻoi aku ka maikaʻi o ka haʻalele ʻana i nā mea pale H2 a koho i kahi PPI. E kamaʻilio pū me kāu kauka e pili ana i kēia.

ʻO ka mea hope loa, nā mea e hoʻomanaʻo ai (Leka Lawe-Home)

ʻAe, ua kamaʻilio nui mākou e pili ana i nā mea pale H2 i kēia lā, ʻeā?

Hoʻohana ʻia nā mea pale H2, nā antacid, a me nā PPI e mālama i nā kūlana i hoʻokumu ʻia e ka nui o ka waikawa o ka ʻōpū. I kekahi manawa, me ka nui o nā koho, hiki ke huikau ka ʻike ʻana i ka mea e koho ai.

E noʻonoʻo i kēia ʻano: Inā ʻoe e ʻimi nei i ka hoʻomaha pōkole e mau ana no kekahi mau hola, ʻo nā mea pale H2 paha ke koho maikaʻi loa nāu. ʻOi loa inā ʻike ʻoe e loaʻa paha iā ʻoe ka ʻeha puʻuwai ma hope o ka ʻai ʻana i kahi mea ʻala, he manaʻo maikaʻi e lawe i kahi mea pale H2 ma mua.

E hoʻomanaʻo, inā he mau nīnau hou kāu e pili ana i kēia lāʻau lapaʻau, mai makaʻu e nīnau i kāu kauka. He mea nui loa ka ʻike e pili ana i kou olakino!

Nā mea pale H2 , gastritis, mumū o ka ʻōpū, waikawa o ka ʻōpū, mumū o ka umauma, nā ʻōpū ʻeha, nā ʻatikala lapaʻau Sinhala