Makemake pū ʻoe e ʻike e pili ana i ka Hairy Cell Leukemia? E kamaʻilio kākou!

Ke luhi mau nei ʻoe? A i ʻole ke ʻeha mau nei ʻoe i ke anu a me nā maʻi? I kekahi manawa ua manaʻo ʻia kēia mau mea he mea maʻamau, akā ʻaʻole hiki ke lilo i hōʻailona o kahi mea ʻē aʻe. I kēia lā e kamaʻilio mākou e pili ana i kahi maʻi koko kakaʻikahi akā koʻikoʻi loa he mea nui loa e makaʻala. Ua kapa ʻia ʻo "Hairy Cell Leukemia".

He aha kēia "Hairy Cell Leukemia"?

I ka ʻōlelo maʻalahi, he ʻano maʻi kanesa kēia e hoʻomaka ana i loko o ke koko. Loaʻa iā mākou kahi ʻāpana o ko mākou kino i kapa ʻia ʻo ka iwi iwi. Mai ia iwi iwi mai i hana ʻia ai nā ʻano o nā cell i loko o ko mākou koko. No kēia mau mea, ʻo nā cell-B (i kapa ʻia hoʻi ʻo 'B lymphocytes') he ʻano o nā cell koko keʻokeʻo. ʻO kā lākou hana nui ka hakakā ʻana i nā germs e komo i loko o ko mākou kino a pale iā mākou mai nā maʻi.

No laila, ma kēia kūlana i kapa ʻia ʻo 'Hairy Cell Leukemia', ʻo ka mea e hana ʻia ana, ʻo ia ka hana ʻana o kou iwi iwi i nā cell-B ʻano ʻē . Ke nānā ʻoe i kēia mau cell ʻano ʻē ma lalo o kahi microscope, hiki iā ʻoe ke ʻike he mau puka liʻiliʻi e like me ka lauoho e puka mai ana mai loko mai o lākou. ʻO ia ke kumu i kapa ʻia ai kēia maʻi ʻo "hairy cell leukemia" ma muli o kēlā ʻano "huluhulu". Ua ʻike ʻia e nā pathologists nāna e nānā i nā cell ma lalo o kahi microscope.

No ke aha e hana ʻia ai kēia? He aha ka mea e hana ʻia i ke kino?

ʻOiai ʻaʻole i ʻike maopopo ʻia ke kumu o kēia hana, aia kekahi mau mea e hana ʻia i ke kino ke hana ʻia kēia ʻano. E noʻonoʻo he māla mea kanu kāu, a he aha ka mea e hana ai inā ulu ka mauʻu me ke kaohi ʻole? Nalowale ka hakahaka o nā mea kanu maikaʻi a ʻaʻole ulu pono, ʻeā? Pēlā nō hoʻi ka mea e hana ʻia ma ʻaneʻi.

• Nā hopena o ka iwi iwi: Hoʻomaka kēlā mau cell-B ʻano ʻē e hōʻiliʻili i loko o ka iwi iwi, e like me nā nāhelehele. Hoʻemi kēlā i ka hiki ke hana i nā cell koko keʻokeʻo olakino, nā cell koko ʻulaʻula, a me nā platelets (nā cell e kōkua i ke kāpili ʻana o ke koko).
• Nā pūnana Lymph a me ka pehu ʻana o ka spleen: Hoʻomaka kēia mau pūnaewele maʻamau i loko o kā mākou mau pūnana lymph a me ka spleen e māhele a hoʻonui, e hoʻoulu ai i kēlā mau ʻōkana.
• Nā hopena o ke akepaʻa: I kekahi manawa hiki i kēia mau ʻāpana ʻano ʻē ke laha i ke akepaʻa ma o ke koko a hōʻino iā ia. Hiki i kēia ke alakaʻi i ka hōʻiliʻili ʻana o ka wai i loko o ka ʻōpū (kahi ʻano i kapa ʻia ʻo 'ascites').

He mea maʻamau kēia?

He maʻi laha ʻole ka `Hairy Cell Leukemia`. ʻOiai ma kahi ʻāina e like me ʻAmelika, loaʻa ia ma kahi o hoʻokahi i loko o hoʻokahi haneli tausani kānaka. Ua ʻōlelo ʻia hoʻi he ʻoi aku ka maʻamau o kēia ʻano ma waena o ka poʻe keʻokeʻo ma mua o nā hui lāhui ʻē aʻe.

He aha nā hōʻailona?

I kekahi manawa , ʻaʻohe hōʻailona o ka poʻe me ka `Hairy Cell Leukemia`. Eia nō naʻe, ke ʻike ʻia nā hōʻailona, ​​hiki iā lākou ke hōʻike i nā mea e like me:

• Luhi: Hiki ke hana ʻia kēia luhi ma muli o ka emi ʻana o nā pae koko ʻulaʻula (anemia).
• Ke kuni a me nā maʻi pinepine:Ma muli o ka haʻahaʻa o nā pae koko keʻokeʻo olakino e hakakā nei i ka maʻi, ʻoi aku ka nui o ka hiki ʻana mai o nā anu pinepine a me nā maʻi koʻikoʻi.
• ʻEha ʻōpū hema lalo: Ke hōʻiliʻili nā pūnaewele ʻano ʻē i loko o ka spleen a hoʻoulu i ka spleen e pehu, hiki iā ʻoe ke ʻeha ma ka ʻāpana ʻōpū hema lalo. Hiki i ka spleen ke hoʻonui a hoʻopiha iā ʻoe, a hiki iā ʻoe ke piha ma hope o ka ʻai ʻana i kahi liʻiliʻi. Hiki iā ʻoe ke emi ke kaumaha me ka hoʻāʻo ʻole.
• ʻEha ma ka ʻōpū ʻākau lalo: Inā hoʻonui ʻia ke akepaʻa, hiki iā ʻoe ke ʻeha ma ka ʻaoʻao ʻākau.
• Paʻakikī ka hanu ʻana: ʻO kēia kekahi hōʻailona o ka anemia.
• Nā kini lymph pehu: Hiki ke ʻike ʻia nā puʻupuʻu ʻeha ʻole ma ka ʻāʻī, nā armpits, a me ka ʻōpū.
• ʻO ka palapū a i ʻole ke kahe koko maʻamau ʻole: No ka mea, ʻaʻole hana ka iwi iwi i nā platelets lawa, e kōkua ana i ke kāpili ʻana o ke koko, hiki i nā palapū liʻiliʻi loa a me ke kahe koko ke hana ʻia.

He mea nui: ʻO ka loaʻa ʻana o hoʻokahi a ʻoi aku paha o kēia mau hōʻailona ʻaʻole ia he manaʻo he Hairy Cell Leukemia kou. Eia nō naʻe, inā hoʻomau kēia mau hōʻailona, ​​​​ʻoi aku ka maikaʻi o ka ʻimi ʻana i ke kōkua lapaʻau.

He aha nā kumu? Aia kekahi mau mea pilikia?

ʻAʻole ʻike nā loea i ke kumu kikoʻī o ka Hairy Cell Leukemia. Eia nō naʻe, ua ʻike ʻia e ka noiʻi he 90% o ka poʻe me ka maʻi he mutation genetic. Hoʻopilikia ia i kahi gene i kapa ʻia ʻo BRAF. Kōkua kēia gene i nā cell e ulu. No laila, ke loli ia, hoʻomaka nā cell ʻano ʻē e ulu a hoʻonui me ka hiki ʻole ke kāohi. Hana ʻia kēia loli genetic ma hope o ko kākou hānau ʻana. Eia naʻe, ʻaʻole maopopo i ke kumu o kēlā loli.

Eia nō naʻe, ua ʻike ʻia kekahi mau mea pilikia e hoʻonui ai i ka pilikia o ka hoʻomohala ʻana i kēia maʻi:

• Makahiki: Hoʻopilikia pinepine kēia maʻi i ka poʻe ma waena o 40 a me 70 mau makahiki. ʻO ka awelika o ka makahiki i ka wā i ʻike ʻia ai ka maʻi ma kahi o 58 mau makahiki.
• Kāne: ʻOi aku ka maʻamau o kēia maʻi i nā kāne ma mua o nā wahine.
• Ka hōʻike ʻana o ka Agent Orange: Manaʻo nā kānaka noiʻi aia kahi pilina ma waena o kēia kemika a me ka leukemia B-cell mau loa a me ka lymphoma (me ka leukemia cell lauoho).

He aha nā pilikia e hiki ai i kēia ke hana?

ʻO ka Hairy Cell Leukemia ke kumu o ka emi nui ʻana o ka nui o nā hunaola koko keʻokeʻo i loko o kou kino e hakakā ana i ka maʻi, kahi e hoʻonui ai i kou pilikia o ka loaʻa ʻana o nā maʻi . Hiki i kēia ke lilo i maʻi bacteria, viral, a fungal paha. I kekahi manawa, hiki i kēia mau maʻi ke hoʻoweliweli i ke ola.

Aia kekahi manawa liʻiliʻi e loaʻa ai kahi ʻano maʻi ʻaʻai ʻelua i nā makahiki he nui ma hope o ka ʻike ʻana a me ka mālama ʻana. No ka laʻana, ua hōʻike nā haʻawina i hahai i nā poʻe i mālama pono ʻia no ka 'Hairy Cell Leukemia' no 10-20 mau makahiki i nā hihia o kekahi poʻe e loaʻa ana i nā maʻi ʻaʻai ʻē aʻe.

Pehea e ʻike ʻia ai kēia maʻi?

Ke ʻike ʻoe i ke kauka, e nīnau ʻo ia iā ʻoe e pili ana i nā mea e like me ka wā i hoʻomaka ai kāu mau hōʻailona a inā loaʻa pinepine iā ʻoe nā maʻi. E nīnau pū ʻo ia e pili ana i kou mōʻaukala olakino. A laila, e hana lākou i kahi hoʻokolokolo kino. Hiki paha iā lākou ke nānā i kāu mau lymph nodes, spleen, a me ke akepaʻa no ka pehu ʻana.

A laila, hiki ke kuhikuhi ʻia ʻoe i kahi hematologist a i ʻole oncologist lapaʻau no nā hoʻokolohua hou aʻe e hōʻoia i ka hōʻailona. Hiki i kēia mau hoʻokolohua ke komo pū me:

• Helu koko piha (CBC) a me ka ʻokoʻa: Ke ana kēia i ka helu o nā hunaola koko ʻulaʻula a me ke keʻokeʻo, a me nā platelets. Ke ana nei ka ʻokoʻa i ka helu o nā ʻano hunaola koko keʻokeʻo like ʻole.
• ʻO ka paʻi koko peripheral: Nānā nā pathologists i kahi hāpana koko ma lalo o kahi microscope e ʻimi i nā cell maʻamau me nā protrusions e like me ka "lauoho".
• ʻO ka makemake ʻana i ka ʻiʻo iwi a me ka biopsy ʻiʻo iwi: Hiki i kēia mau hoʻokolohua ke ʻike i nā cell ʻano ʻē i loko o ka ʻiʻo iwi.
• ʻO ke scan CT (Computed tomography - `CT` scan): Hiki i ke scan `CT` ke kiʻi i nā kiʻi kikoʻī o loko o ke kino. Hiki ke hoʻohana ʻia kēia e ʻike i ka nui o ka spleen, ke akepaʻa, a me nā lymph nodes, a i ʻole he ultrasound o ka ʻōpū.
• ʻO ke kahe ʻana o ka cytometry: Nānā kēia i ke koko a me ka iwi iwi no nā pūnaewele ʻē, e like me nā pūnaewele lauoho. Nānā pū ia i ka nui, ke ʻano o nā pūnaewele, a me ke alo o nā māka tumor. Hiki i nā māka tumor ke lilo i mau protein i hana ʻia e nā pūnaewele kanesa.

Pehea e mālama ʻia ai?

Inā loaʻa iā ʻoe kahi maʻi, pono ʻoe e mālama mua. A laila, e hoʻomaka ʻia nā lāʻau ʻē aʻe e kāohi i nā hōʻailona o ka 'Hairy Cell Leukemia'. Eia naʻe, e like me kā mākou i ʻōlelo ai ma mua, ʻaʻole e loaʻa i nā kānaka a pau nā hōʻailona. No kēlā poʻe, hiki i kāu hematologist a oncologist paha ke kuhikuhi i kahi ʻano i kapa ʻia ʻo active surveillance . Inā he mau hōʻailona, ​​​​hiki iā lākou ke kuhikuhi i nā lāʻau lapaʻau.

Nānā Hana

He maʻi ulu lohi loa ka Hairy Cell Leukemia. Hiki ke hala nā makahiki no ka ʻike ʻia ʻana o nā hōʻailona. No ka mea hiki i nā lāʻau lapaʻau maʻi kanesa ke hana i nā hopena ʻaoʻao a me nā pilikia, inā ʻaʻohe hōʻailona o kou ʻano, hiki i kāu kauka ke hoʻoholo e hoʻopaneʻe i ka hoʻomaka ʻana o ka lāʻau a hiki i ka ʻike ʻia ʻana o nā hōʻailona.

I ka wā o ka nānā pono ʻana, e ʻike ʻoe i kāu kauka i kēlā me kēia ʻekolu a ʻeono mahina. I loko o kēlā mau kipa:

• E nīnau lākou e pili ana i kou olakino holoʻokoʻa, ʻoiai inā ʻoi aku kou luhi ma mua o ka maʻamau.
• E hana ʻia kahi hoʻokolohua kino e nānā ai i ka pehu ʻana o ke akepaʻa a me ka spleen.
• Hoʻoholo ʻia nā hoʻāʻo koko e hoʻoholo i ke kiʻekiʻe o nā sela koko a me nā platelet.

Hiki ke paʻakikī iki ka naʻau ke kali a ʻike ʻia nā hōʻailona ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau. Akā e hoʻomaopopo kāu kauka i kou mau manaʻo a wehewehe i ke kumu e ʻōlelo ʻia ai ka nānā pono ʻana.

Lāʻau lapaʻau

ʻO ke chemotherapy ka lāʻau lapaʻau mua no ka poʻe me ka leukemia cell hairy. ʻO nā lāʻau anticancer i hoʻohana pinepine ʻia ʻo Cladribine (Leustatin®) a i ʻole Pentostatin (Nipent®).

Inā ʻaʻole holo pono ka chemotherapy, a inā hoʻi hou ka maʻi, aia kekahi mau lāʻau lapaʻau ʻē aʻe:

• ʻO ka Immunotherapy: ʻO ka `Rituximab (Rituxan®)` he lāʻau `monoclonal antibody` i hoʻohana ʻia no ka `Hairy Cell Leukemia`. Hiki ke hāʻawi ʻia ma ke ʻano he lāʻau mua me ka chemotherapy a i ʻole inā hoʻi hou ka maʻi. ʻO kekahi immunotherapy ʻo `Recombinant Interferon Alfa-2b (Intron A®)`.
• Lapaʻau i hoʻolālā ʻia: No ka Hairy Cell Leukemia i hoʻi hou mai, hiki ke hoʻohana ʻia nā lāʻau i kapa ʻia ʻo Rituximab lāua ʻo Moxetumomab pasudotox (Lumoxiti®) (he ʻano hui pū ʻia kēia o ka antibody-drug).
• Splenectomy: He mea kākaʻikahi loa, hiki ke ʻōlelo ʻia kēia ʻoki inā ʻaʻole kōkua nā lāʻau lapaʻau e like me ka chemotherapy a hoʻomau ka pehu ʻana o ka spleen ma muli o nā cell maʻamau ʻole i loko o ka spleen.

Aia kekahi mau hopena ʻaoʻao o ka lāʻau lapaʻau?

E like me nā lāʻau lapaʻau maʻi kanesa, hiki iā ia ke loaʻa nā hopena ʻaoʻao. ʻOi aku ka nui, ʻo nā lāʻau chemotherapy no ka leukemia cell hairy e hoʻonui i ka pilikia o nā maʻi e hoʻoweliweli ana i ke ola . E wehewehe kāu kauka iā ʻoe i nā hana āu e hiki ai ke hana e pale aku i nā maʻi a me nā loli i kou kino e hiki ke lilo i mau hōʻailona o ka maʻi.

He aha kāu e manaʻo ai i kou wā e ola nei me kēia maʻi?

ʻAʻohe lāʻau lapaʻau no ka Hairy Cell Leukemia i kēia manawa . Eia nō naʻe, hōʻike ka noiʻi e hiki i ka lāʻau lapaʻau, me ka chemotherapy, ke hoʻomau i ka maʻi no 10 mau makahiki a ʻoi aku paha . ʻO ke kala ʻana, ʻo ia hoʻi, ʻaʻohe ou hōʻailona a ʻaʻohe hōʻailona o ka maʻi e loaʻa ma nā hoʻokolohua. Ua ʻike ʻia kahi noiʻi i kālailai i nā ʻike o ka poʻe me Hairy Cell Leukemia ma hope o ka lāʻau lapaʻau, hiki iā lākou ke ola e like me ka poʻe me ka ʻole o ka maʻi.

Eia nō naʻe, hiki i ka leukemia cell hairy ke hoʻi hou mai i kekahi mau makahiki ma hope o ka mālama mua ʻana. Eia nō naʻe, inā hana ʻia kēlā, aia nā lāʻau lapaʻau e hiki ai ke hoʻihoʻi i ka maʻi i ke kala ʻana.

He nui ka poʻe e pono ai ke kōkua olakino a me ke kākoʻo no ke ola holoʻokoʻa, no ka mea, pono nā kauka e nānā i nā hoʻi hou ʻana. ʻOiai inā loaʻa iā ʻoe ka maʻi akā ʻaʻohe hōʻailona, ​​​​pono ʻoe e loaʻa nā hoʻokolohua a me nā manawa hoʻopaʻa i kēlā me kēia ʻekolu a ʻeono mahina ma hope o ka hōʻoia ʻana.

He aha ka helu ho'ōla?

Wahi a ka Leukemia and Lymphoma Society, 90% o ka poʻe i mālama ʻia me ka lāʻau chemotherapy ʻo Cladribine e ola ana i ʻelima mau makahiki ma hope o ka mālama ʻana. Eia nō naʻe, ʻo kāu prognosis - ka mea e hana ʻia ma hope o ka mālama ʻana - e hilinaʻi ʻia i nā kumu he nui . ʻO kou makahiki, ke olakino holoʻokoʻa, nā hōʻailona, ​​a me ke ʻano o ka pane ʻana o kou kino i ka mālama ʻana he kuleana ko lākou. Inā he mau nīnau kāu e pili ana i kēia, e nīnau i kāu kauka.

Pehea lā wau e mālama ai i koʻu olakino?

Hoʻonui ka Hairy Cell Leukemia i ka pilikia o nā maʻi e hoʻoweliweli ana i ke ola. Hiki iā ʻoe ke hoʻoikaika i kāu ʻōnaehana pale a pale iā ʻoe iho mai nā maʻi . Eia kekahi mau manaʻo:

• E ʻai i ka meaʻai olakino: ʻO nā mea e like me nā huaʻai, nā mea kanu, nā protein lean, a me nā palaoa holoʻokoʻa e kōkua i ka hana ʻōnaehana pale.
• Hoʻoikaika kino i kēlā me kēia lā: ʻO ka hana ikaika i kēlā me kēia lā he mea maikaʻi ia no nā ʻano he nui o kou olakino, me kāu ʻōnaehana pale kino.
• E hiamoe nui: ʻO ka loaʻa ʻole o ka hiamoe nui e hiki ai ke hoʻemi i ka maikaʻi o kāu ʻōnaehana pale.
• E kiʻi i kāu mau lāʻau pale i ka manawa kūpono: Hoʻomaʻamaʻa nā lāʻau pale i kou kino e hakakā i nā germs e hoʻoulu ai i nā maʻi. E kamaʻilio me kāu kauka e pili ana i nā lāʻau pale āu e pono ai a me ka wā e kiʻi ai iā lākou.

Āhea ʻoe e ʻike ai i ke kauka?

Hiki i ka Hairy Cell Leukemia a me kāna lāʻau lapaʻau ke hoʻonui i kou pilikia o ka loaʻa ʻana o nā maʻi koʻikoʻi, i kekahi manawa e hoʻoweliweli ana i ke ola. E ʻike koke i ke kauka inā loaʻa iā ʻoe kēia mau hōʻailona:

• He kuni i ʻoi aku ma mua o 38 kekelē Celsius (100.4 kekelē Fahrenheit) a ʻaʻole i iho.
• ʻO ka ʻeha o ka ʻāʻī e mau ana ma mua o kekahi mau lā a i ʻole e ʻoi aku ka ʻino.
• ʻEha ʻōpū ʻaʻole e nalo a i ʻole e ʻoi aku ka ʻino.

Hōʻuluʻulu Manaʻo a me ka Hope (Leka Lawe-Home)

Malia paha ua luhi loa ʻoe ma mua o ka maʻamau me ke kumu ʻole. A i ʻole ua noʻonoʻo paha ʻoe i kahi maʻi hanu i nalowale ʻole me ka nānā ʻole i nā lāʻau lapaʻau āpau āu i lawe ai. I kēia manawa ua hōʻike ʻia nā hoʻokolohua he maʻi koko laha ʻole kou i kapa ʻia ʻo 'Hairy Cell Leukemia', kahi mea hiki ʻole ke ho'ōla ʻia me ka lāʻau lapaʻau.

, . ‍ ‍ . `remission` ‍ ‍ . , `Hairy Cell Leukemia` , `remission` ‍ .

Aia kekahi mau mea hiki iā ʻoe ke hana ma kāu ʻaoʻao. No ka laʻana, hiki i nā lāʻau lapaʻau maʻi kanesa ke hoʻonui i kou pilikia o ka maʻi. E nīnau i kāu kauka e pili ana i nā lāʻau pale a me nā hana ʻē aʻe hiki iā ʻoe ke hana e hōʻemi i kou pilikia o ka maʻi.ʻAʻole ʻoe hoʻokahi, aia nā kauka a me nā limahana mālama ola e kōkua iā ʻoe ma kēia huakaʻi.

ʻO ka maʻi leukemia o nā cell huluhulu, leukemia, maʻi ʻaʻai koko, nā cell B, ka iwi ʻiʻo, ka spleen, nā hōʻailona