He HER2-Positive anei kou maʻi ʻaʻai umauma? E kamaʻilio kākou e pili ana i kēia me nā kikoʻī!

Ua lohe paha ʻoe i ke kanesa o ka umauma? Malia paha ua loaʻa i kahi hoaaloha a ʻohana paha kou. Aia kekahi mau ʻano kanesa o ka umauma like ʻole. I kēia lā e kamaʻilio mākou e pili ana i kekahi o lākou, he mea kūikawā a hiki ke laha wikiwiki iki. ʻO ia ka maʻi kanesa o ka umauma HER2-Positive (HER2-positive) . Ke lohe ʻoe i kēia inoa, manaʻo paha ʻoe he mea paʻakikī iki ia, akā mai hopohopo. E kamaʻilio maʻalahi mākou e pili ana iā ia, ma ke ʻano hiki iā ʻoe ke hoʻomaopopo.

He aha ka maʻi ʻaʻai umauma HER2-Positive (HER2+)?

I ka ʻōlelo maʻalahi, ʻo ka maʻi ʻaʻai umauma HER2-positive (HER2+) he ʻano maʻi ʻaʻai e ulu koke ana a hiki ke laha maʻalahi ma waho o ka umauma (`invasive`) . Ke ʻōlelo nā kauka he ʻano maʻi ʻaʻai kou, ʻo ia hoʻi, he kiʻekiʻe nā pae o kahi protein kūikawā i loko o kāu mau cell maʻi ʻaʻai e kāohi ana i ka ulu ʻana a me ka mahele ʻana o nā cell i loko o kou kino - i kapa ʻia ʻo "Human Epidermal Growth Factor Receptor 2" , a i ʻole HER2 no ka pōkole. Ua like kēia protein HER2 me kahi "hōʻailona" e haʻi ana i nā cell e ulu. Ke nui loa ia, māhele koke nā cell a hiki ʻole ke kāohi ʻia, e alakaʻi ana i ka maʻi ʻaʻai.

ʻOi aku ka nui o ka laha ʻana o kēia ʻano maʻi ʻaʻai umauma (metastasize) mai ka umauma a i nā ʻāpana ʻē aʻe o kou kino, e like me nā lymph nodes, ke akepaʻa, nā māmā, a i ʻole kou lolo. Akā ʻo ka mea nui, inā ʻike mua ʻia kēia maʻi ʻaʻai, ma mua o kona laha ʻana i nā ʻāpana ʻē aʻe o ke kino, hiki i nā kauka ke mālama pono iā ia me nā lāʻau lapaʻau holomua i loaʻa i kēia lā. ʻO ia ke kumu he mea nui ka ʻike mua ʻana.

Pehea ka maʻamau o ka maʻi ʻaʻai umauma HER2-positive?

Wahi a ka American Cancer Society, e ʻoi aku ma mua o 290,000 mau wahine e ʻike ʻia me ka maʻi ʻaʻai umauma invasive (invasive ductal carcinoma a me ka maʻi ʻaʻai umauma lobular) i ka makahiki 2023 wale nō. Ma waena o kēia mau mea , he 15% a 20% he HER2-positive. Hiki i nā kāne ke loaʻa i ka maʻi ʻaʻai umauma, akā ʻoi aku ka liʻiliʻi o ka maʻi ʻaʻai umauma HER2-positive i nā kāne.

He aha nā hōʻailona o ka maʻi ʻaʻai umauma HER2-positive?

E like me nā ʻano maʻi ʻaʻai umauma he nui, ʻaʻole hōʻike kēia ʻano HER2-positive i nā hōʻailona maopopo i ka wā mua. Akā i ka wā e ʻike ʻia ai nā hōʻailona, ​​ua like lākou me nā mea i ʻike ʻia i ka maʻi ʻaʻai umauma maʻamau. E nānā kākou i ke ʻano o lākou:

• He loli i ka nui, ke ʻano, a i ʻole ke ʻano o ka umauma . Hiki i kekahi umauma ke manaʻo ʻia he ʻoi aku ka nui ma mua o kekahi, a i ʻole e loli paha kona ʻano.
• He puʻupuʻu a puʻupuʻu paha ma ka umauma a i ʻole ka ʻāpana lima. Hiki i kēia ke liʻiliʻi e like me ka pī. Inā hoʻomau ka puʻupuʻu ma hope o ka pau ʻana o kāu pōʻaiapuni menstrual, pono ʻoe e hopohopo.
• He loli i ke ʻano a i ʻole ke ʻano o ka ʻili o ka umauma a i ʻole ka nipple. Hiki i ka ʻili ke lilo i ʻākala, ʻōniʻoniʻo a ʻūlū paha, a i ʻole e like me ka unahi a pehu paha. I kekahi manawa ʻulaʻula a ʻeleʻele paha ka ʻili ma mua o ka maʻamau.
• Ke manaʻo nei i kahi ʻāpana paʻakikī ma lalo o ka ʻili, e like me ke kinikini .
• He wai koko a moakāka paha e puka mai ana mai loko mai o ka nipple.

E noʻonoʻo, e kou hoaaloha, e kapa kākou iā ia ʻo "Sunita". I kekahi lā, i kona ʻauʻau ʻana, ua ʻike ʻo Sunita i kahi loli liʻiliʻi i loko o kona umauma. Ua like ia me kahi puʻupuʻu liʻiliʻi. I ka wā mua, ʻaʻole ʻo ia i nānā nui iā ia, me ka manaʻo, "E nalo wale nō ia." Akā ma hope o kekahi mau pule, aia nō ia ma laila. Ma hope mai, i kona hōʻike ʻana i ke kauka, ua ʻike ʻo ia he hōʻailona ia o ka maʻi ʻaʻai umauma. No laila, inā ʻike ʻoe i kekahi mau loli ʻē i loko o kou mau umauma, he mea nui loa ia e ʻimi i ka ʻōlelo aʻo lapaʻau me ka nānā ʻole ʻana iā ia.

He aha ke kumu o ka maʻi ʻaʻai umauma HER2-positive?

Hoʻokumu ʻia ka maʻi ʻaʻai umauma HER2-positive e kahi mutation i loko o kahi gene i kapa ʻia ʻo HER2. Hoʻopuka kēia gene HER2 i ka protein HER2 a mākou i kamaʻilio ai ma mua. Loaʻa kēia mau protein HER2 (i kapa ʻia hoʻi he 'receptors') ma ka ʻili o nā hunaola umauma āpau.

Ma lalo o nā kūlana maʻamau, hoʻomalu kēia mau protein HER2 i ka ulu ʻana a me ka hoʻoponopono ʻana o nā cell umauma, e hōʻoiaʻiʻo ana e māhelehele ana nā cell hou i nā helu lawa e pani i nā cell i hōʻino ʻia a make paha.

Eia nō naʻe, ke hoʻololi ʻia ka gene HER2, hana ia i nā kope he nui o ia iho. Ke hoʻonui nui ʻia ka gene HER2, hana pū ia i ka nui o ka protein HER2. Ke nui loa ka protein HER2, māhele koke nā hunaola umauma a ulu me ke kāohi ʻole ʻia, e lilo ana i mau puʻupuʻu kanesa.

He aha nā kumu pilikia no kēia?

E like me ke kanesa o ka umauma, ua like nā kumu pilikia no ka maʻi kanesa o ka umauma HER2-positive me ke kanesa o ka umauma maʻamau. Hiki iā ʻoe ke loaʻa i ka maʻi kanesa o ka umauma inā loaʻa iā ʻoe kēia mau mea pilikia a i ʻole. Eia naʻe, hiki i kēia mau mea ke hoʻonui i kou pilikia:

• Loaʻa kahi hoʻololi hoʻoilina i hoʻoilina ʻia . Eia kekahi laʻana, kahi hoʻololi i loko o nā genes BRCA1 a i ʻole BRCA2.
• Ua loaʻa mua iaʻu ka maʻi ʻaʻai umauma.
• Loaʻa nā maʻi ʻē aʻe e pili ana i ka umauma e like me ka 'atypical ductal hyperplasia'.
• Hoʻomaka mua ka pōʻaiapuni menstrual ma mua o ka maʻamau.
• Hiki mai ka menopause ma hope o ka makahiki maʻamau.
• Ke lawe nei i ka lāʻau lapaʻau hoʻololi hormone.
• ʻO ka inu ʻana ma mua o hoʻokahi mea inu ʻona i ka lā.
• Ua loaʻa ka radiation therapy no kekahi mau kūlana e like me ka lymphoma (ka maʻi ʻaʻai o ka ʻōnaehana lymphatic).

He aha nā pilikia o ka maʻi ʻaʻai umauma HER2-positive?

Hiki i ka maʻi ʻaʻai umauma HER2-Positive ke laha i nā ʻāpana ʻē aʻe o ke kino, a i ʻole 'metastasize'. Ma kahi o ka hapalua o ka poʻe me kēia ʻano maʻi ʻaʻai umauma, ua laha mua ke kanesa i nā ʻāpana ʻē aʻe o ke kino, ʻoiai ka lolo, i ka manawa i ʻike ʻia ai lākou. ʻO ke kanesa umauma i laha i ka lolo ('metastatic breast cancer to your brain') hiki ke hoʻoweliweli i ke ola. ʻO ia ke kumu he mea nui ka ʻike mua ʻana a me ka mālama koke ʻana.

Pehea e ʻike ʻia ai ka maʻi ʻaʻai umauma HER2-positive?

Hoʻohana nui nā kauka i ka biopsy umauma e ʻike i nā maʻi ʻaʻai umauma āpau. Pili kēia i ka lawe ʻana i kahi ʻāpana liʻiliʻi mai kahi wahi kānalua o ka umauma a nānā iā ia ma lalo o kahi microscope.

Inā hōʻoia ka biopsy umauma he maʻi kanesa, e hana kekahi kauka lapaʻau (he kauka loea i ka ʻike ʻana i nā maʻi) i nā hoʻokolohua kūikawā e ʻike ai inā loaʻa i nā pūnaewele ʻiʻo umauma ka protein HER2. ʻElua ʻano nui o nā hoʻokolohua no kēia:

1. Immunohistochemistry (IHC): Hiki i kēia hoʻāʻo i nā pathologists ke ʻimi i ka protein HER2 i loko o nā cell cancer umauma. Hoʻohana kēia hoʻāʻo i kahi dye kūikawā (immunostaining) e nānā i ka pae o ka protein HER2 i loko o nā cell cancer.

2. Fluorescence in situ hybridization (FISH): Hoʻohana ʻia kēia hoʻāʻo FISH i kekahi manawa e hōʻoia i nā hopena o ka hoʻāʻo IHC. Hiki i kēia hoʻāʻo ke ʻike inā he mau kope keu o ka gene HER2.

Ma hope o kēia mau hoʻokolohua, hoʻokaʻawale hou nā kauka i ke kanesa. Hoʻohana lākou i kahi 'ʻōnaehana helu'. Nānā kēia i ke kiʻekiʻe o ka pae o ka protein HER2 i loko o ka hāpana ʻiʻo umauma, a me ka nui o nā hunaola kanesa i loaʻa. E noʻonoʻo e pili ana i kēia ʻano:

• Inā hōʻike ka hoʻāʻo ʻana ua haʻahaʻa ka pae protein HER2, e helu ʻia he 0 a i ʻole 1+ . A laila e ʻōlelo ke kauka pathology he HER2 maikaʻi ʻole ia.
• Inā he mau hunaola kanesa a he kaulike ka pae protein, hiki iā ʻoe ke loaʻa kahi helu o 2+ . A laila e hōʻoia pū ka pathologist i ka hoʻāʻo 'FISH' i ʻōlelo ʻia ma mua.
• Inā he nui nā hunaola kanesa a kiʻekiʻe loa ka pae protein, loaʻa iā ʻoe kahi helu o 3+ . ʻO ia ka manawa e ʻōlelo ai ka pathologist he HER2 maikaʻi .

Hoʻoholo pololei kēia ʻōnaehana helu inā he HER2-maikaʻi ʻoe a he HER2-maikaʻi ʻole paha.

He aha nā lāʻau lapaʻau no ka maʻi ʻaʻai umauma HER2-positive?

No ka mea he ʻano "invasive" kēia o ka maʻi ʻaʻai umauma, ua hoʻoholo ʻia nā koho lapaʻau e nā kumu he nui, e like me ke kahua o ke kanesa a me ke kūlana HER2. Hiki ke hoʻohana ʻia nā lāʻau lapaʻau aʻe:

• Hoʻōla i kuhikuhi ʻia:ʻO kēia ka lāʻau lapaʻau kikoʻī loa no ka maʻi kanesa HER2-positive. Pili ia i ka hāʻawi ʻana i nā lāʻau lapaʻau e kuhikuhi ana i ka protein HER2 a pepehi i nā hunaola kanesa. Aia kekahi mau ʻano lapaʻau nui ma lalo o kēia:
• ʻO ka lāʻau lapaʻau antibody monoclonal: Hoʻopaʻa kēia i ka protein HER2 a hoʻōki i ka ulu ʻana o nā hunaola kanesa.
• ʻO ka lāʻau lapaʻau Tyrosine kinase inhibitor: Komo kēia mau lāʻau lapaʻau i loko o nā hunaola kanesa a ālai i nā ala hōʻailona e kōkua ai i ka ulu ʻana o nā hunaola.
• Nā hui lāʻau lapaʻau antibody (ADCs): He ʻano holomua loa kēia. Ma kēia, hoʻopili ʻia kahi lāʻau anti-cancer i kahi antibody e ʻimi nei i nā cell cancer. A laila hele pololei kēia hui i nā cell cancer a hoʻokuʻu i ka lāʻau, e hōʻemi ana i ka hōʻino ʻana i nā cell olakino.
• Kemoterapia: Hāʻawi ʻia ka kemoterapia ma mua o ke ʻoki ʻana e hoʻēmi i ka puʻupuʻu (neoadjuvant therapy) a i ʻole e pepehi i nā hunaola kanesa i koe ma hope o ke ʻoki ʻana (adjuvant therapy). I kekahi manawa hāʻawi pū ʻia ka kemoterapia me ka kemoterapia i kuhikuhi ʻia.

Ma waho aʻe o kēia, ma muli o ke kahua o ke kanesa, hiki ke hana ʻia nā mea e like me ke 'ʻoki kino', 'radiation therapy', a i ʻole 'hormone therapy'.

He aha nā hopena ʻaoʻao o nā lāʻau lapaʻau?

Hiki ke ʻokoʻa nā hopena ʻaoʻao ma muli o ka lāʻau lapaʻau. Inā ʻoe e loaʻa ana i ka lāʻau lapaʻau, e kamaʻilio me kāu kauka e pili ana i ka hopena o ka lāʻau lapaʻau iā ʻoe a pehea e pili ai i kou ola o kēlā me kēia lā. Eia kekahi, e nīnau i kāu kauka e pili ana i ka mālama palliative . ʻO ka mālama palliative kahi lawelawe e kōkua iā ʻoe e hoʻokele i nā hōʻailona o ke kanesa a me nā hopena ʻaoʻao o ka lāʻau lapaʻau a hoʻolilo iā ʻoe i ʻoluʻolu e like me ka hiki i ka wā o ka lāʻau lapaʻau. ʻAʻole wale ia no ka poʻe hiki ʻole ke ho'ōla i ke kanesa, akā hiki ke kōkua i kekahi mea e mālama ʻia ana.

Hiki i kēia mau lāʻau ke ho'ōla loa i ka maʻi ʻaʻai umauma HER2-positive?

Ke ʻōlelo nā kauka e "ho'ōla" lākou i kahi maʻi kanesa, ʻo ia hoʻi, ua hoʻokuʻu ka lāʻau lapaʻau i ke kanesa i ka hoʻomaha no nā makahiki. ʻO ke kala ʻana, ʻo ia hoʻi, ua noa ʻoe i nā hōʻailona o ke kanesa a ʻaʻohe kanesa e hiki ke ʻike ʻia ma nā hoʻokolohua. ʻO ke kanaka i ʻike ʻia he maʻi kanesa umauma HER2-positive, i mālama ʻia, a ola no ʻelima mau makahiki, ua manaʻo ʻia ua "ho'ōla ʻia."

Wahi a ka US National Cancer Institute (NCI), ʻoi aku ma mua o 90% o ka poʻe i ʻike ʻia me ka maʻi ʻaʻai umauma HER2-positive e ola mau ana ma hope o ʻelima mau makahiki. Hiki ke manaʻo ʻia ua ho'ōla ʻia lākou mai ko lākou maʻi ʻaʻai. Eia nō naʻe, hiki i ka maʻi ʻaʻai HER2-positive ke hoʻi hou a laha i nā wahi ʻē aʻe o ke kino. No laila, he mea nui e hoʻomau i ka hele ʻana no nā nānā lapaʻau.

He aha ka nui o ke ola no ka maʻi ʻaʻai umauma HER2-positive?

ʻOkoʻa nō hoʻi nā manawa kūpono e ola ai i ka maʻi ʻaʻai umauma HER2-positive ma muli o ka mea inā he hormone receptor-positive (HR+) a i ʻole hormone receptor-negative (HR-) ke kanesa. (ʻO kēia mau mea loaʻa hormone nā mea loaʻa ma luna o nā cell e hiki ke hoʻopaʻa i nā hormones. Ma kahi o ka hapalua o nā maʻi ʻaʻai HER2-positive āpau i loaʻa kēia mau mea loaʻa. Hoʻokaʻawale ka NCI i kēia mau manawa kūpono ma ke kahua o ke kanesa: kūloko (i kaupalena ʻia i ka umauma), ʻāpana (hoʻolaha i nā lymph node kokoke), a mamao (hoʻolaha i nā ʻāpana mamao o ke kino). Hiki iā ʻoe ke kamaʻilio me kāu kauka e pili ana i kēia e aʻo hou aku.

Hiki ke pale ʻia ka maʻi ʻaʻai umauma HER2-positive?

ʻAʻole paha. ʻOiai aia kekahi mau mea hiki iā ʻoe ke hana e hōʻemi i kou pilikia o ka maʻi ʻaʻai umauma, ʻo ka maʻi ʻaʻai umauma HER2-positive ke kumu o kahi mutation i loko o ka gene HER2 e hoʻoulu ai i nā hunaola kanesa. Ke aʻo nei nā kānaka noiʻi i ke kumu o kēia hana, no laila ʻaʻole hiki iā lākou ke ʻōlelo pololei i ka mea hiki ke hana ʻia e pale aku i ka maʻi ʻaʻai HER2-positive.

Eia nō naʻe, hiki iā ʻoe ke hana i kēia mau mea e hōʻemi i kou pilikia o ka maʻi ʻaʻai umauma ma ke ʻano laulā:

• E mālama i ke olakino o kou umauma. E hana i nā hoʻokolokolo umauma maʻamau, a e kiʻi i nā mammograms i ka makahiki a me nā manawa i ʻōlelo ʻia e kāu kauka. E makaʻala i nā loli i kou mau umauma. Ma kēia ʻano, hiki ke ʻike mua ʻia ka maʻi kanesa a mālama maʻalahi ʻia.
• E mālama i ke kaumaha olakino. Pono kēia e lilo i kaumaha e ʻoluʻolu ai iā ʻoe. E noi i kāu kauka no ka ʻōlelo aʻo no ka mālama ʻana i ke kaumaha olakino.
• E ʻai i ka meaʻai olakino. Ua hōʻike kekahi mau noiʻi e hiki i ka meaʻai waiwai i nā mea kanu, nā huaʻai, nā huahana waiū momona i ka calcium, a me nā protein lean ke hōʻemi i ka pilikia o ka maʻi ʻaʻai umauma. He manaʻo maikaʻi nō hoʻi e kaupalena i ka ʻai ʻana i nā ʻiʻo ʻulaʻula a me nā ʻiʻo i hana ʻia.
• E hana ikaika. Ua hōʻike ʻia nā noiʻi e hōʻemi ana ka hana kino mau i ka pilikia o ka maʻi ʻaʻai umauma. ʻOiai ka hele wāwae wale no 30 mau minuke i ka lā he mea maikaʻi ia.
• E pale i nā mea inu ʻona. Hōʻike ka noiʻi i kahi pilina ma waena o ke kanesa o ka umauma a me ka waiʻona. Paipai ka American Medical Association i nā wahine e kaupalena i kā lākou inu ʻona i hoʻokahi mea inu i kēlā me kēia lā.

Pehea wau e mālama ai iaʻu iho?

ʻO ke ola ʻana me ka maʻi ʻaʻai umauma, ʻo ia hoʻi ke ola ʻana me nā hōʻailona o ka maʻi ʻaʻai, nā lāʻau lapaʻau, a me nā hopena ʻaoʻao o ka lāʻau lapaʻau. A, i kekahi manawa, pono paha ʻoe e noho me ka manaʻo kānalua e pili ana i ka wā e hiki mai ana. Hiki paha iā ʻoe ke manaʻo kaumaha a hoʻonāukiuki i kekahi manawa. Inā manaʻo ʻoe pēlā, e noʻonoʻo i kēia mau manaʻo no ka mālama ʻana iā ʻoe iho:

• E hoʻomaha pono.He mea luhi loa ka maʻi ʻaʻai umauma a me ka mālama ʻana. E hoʻomanaʻo e hoʻomaha i ka wā āu e makemake ai, ʻaʻole wale i ka wā e loaʻa ai ka manawa.
• ʻAi maikaʻi. Hiki i ka lāʻau lapaʻau ke hōʻemi i kou makemake, akā ʻo ka ʻai ʻana i ka meaʻai momona i nā huaʻai, nā mea kanu, nā protein lean, a me nā palaoa olakino e kōkua iā ʻoe e noho ikaika i ka wā o ka lāʻau lapaʻau.
• E hoʻokele i kou kaumaha. ʻO ke kanesa kekahi mea hoʻokaumaha nui. Hiki i ka hoʻoikaika kino ke kōkua i kēia. He mea maikaʻi ka hele wāwae mau a me ke komo ʻana i nā papahana hoʻoikaika kino e like me ka yoga.
• E kiʻi i ke kākoʻo. He mea ola ʻoe i ka maʻi ʻaʻai umauma, a hoʻomaka kēlā i ka lā i ʻike ʻia ai ʻoe. E nīnau i kāu kauka e pili ana i nā papahana ola maʻi ʻaʻai . Hiki i kēia mau mea ke kōkua iā ʻoe e lanakila i nā pilikia o ke ola ʻana me ka maʻi ʻaʻai umauma. ʻO ke kamaʻilio ʻana me kou ʻohana a me kou mau hoaaloha he ala maikaʻi loa ia e kākoʻo ai iā ʻoe iho.

Āhea wau e ʻike ai i ke kauka?

Pono ʻoe e ʻike pinepine i kāu kauka i ka wā o ka mālama ʻana. Eia nō naʻe, inā ʻike ʻoe i kekahi mau loli hou i kou mau umauma a i ʻole ke kino e hiki ke lilo i mau hōʻailona ua laha kāu maʻi ʻaʻai HER2-positive, e haʻi koke i kāu kauka. No ka laʻana, inā ua laha ka maʻi ʻaʻai umauma i nā māmā, hiki iā ʻoe ke ʻike i nā hōʻailona e like me ka ʻeha o ka umauma, nā maʻi umauma pinepine, ka paʻakikī o ka hanu ʻana, a i ʻole ke ʻū ʻana i ke koko.

Āhea wau e hele ai i ka lumi pilikia?

Inā ʻoi aku ka ʻino o ka pane a kou kino i ka mālama ʻana i ka maʻi kanesa ma mua o kou manaʻo, pono ʻoe e hele i ka lumi pilikia. Eia kekahi laʻana, inā ua maloʻo loa ʻoe ma muli o ka luaʻi mau ʻana, e hele koke i ka haukapila.

He aha nā nīnau e pono iaʻu e nīnau aku i kaʻu kauka?

Inā hōʻike kāu mau hoʻokolohua he maʻi ʻaʻai umauma HER2-positive kou, makemake paha ʻoe e nīnau i kāu kauka i nā nīnau e like me:

• He aha maoli koʻu kūlana HER2 ? (ʻo ia hoʻi, he aha kaʻu helu IHC/FISH?)
• He aha ke kūlana o koʻu mea hoʻokipa hormone ? (HR+ a i ʻole HR-?)
• Pehea ka hopena o kēia mau kūlana HER2 a me ka mea loaʻa hormone i kaʻu prognosis (ʻo ia hoʻi, ka prognosis a me ke kaʻina o ka maʻi i ka wā e hiki mai ana)?
• He aha nā lāʻau lapaʻau āu e ʻōlelo mai ai noʻu? No ke aha mai?
• Pono anei iaʻu e noʻonoʻo e komo i kahi hoʻokolohua lapaʻau e mālama i ka maʻi ʻaʻai umauma HER2-positive?

He mea kākaʻikahi nā holomua i ka mālama ʻana i ka maʻi kanesa. ʻO ia ke kumu i hauʻoli nui ai nā kānaka noiʻi kanesa i ka wā i hōʻike ai nā haʻawina e hoʻoulu nā mutations i loko o ka gene HER2 i nā cell e māhele wikiwiki ma mua o ka maʻamau. Ua ʻike koke lākou i kahi pilina ma waena o nā mutations gene HER2 a me kekahi mau ʻano maʻi umauma e ulu wikiwiki ana. Mai laila mai, ua hoʻomohala lākou i nā lāʻau lapaʻau e hiki ke mālama pono i ka maʻi umauma HER2-positive mua. I kēia manawa, ke kālele nei nā kānaka noiʻi i ka loaʻa ʻana o nā lāʻau lapaʻau ʻoi aku ka maikaʻi e hiki ke hoʻolohi a hoʻōki paha i ka laha ʻana o ka maʻi kanesa. ʻO nā hoʻokolohua lapaʻau kahi e hana ʻia ai kēia mau ʻike hou. Inā loaʻa iā ʻoe ka maʻi umauma metastatic ('metastatic'), e kamaʻilio me kāu kauka e pili ana i ke komo ʻana i kahi hoʻokolohua lapaʻau. Hiki iā lākou ke kōkua iā ʻoe.

ʻO ka mea hope loa, leka lawe i ka home

He ʻano maʻi kanesa koʻikoʻi a laha wikiwiki ka maʻi ʻaʻai umauma HER2-positive. Eia nō naʻe, me ka ʻike pololei a me ka wā mua a me nā koho lapaʻau holomua, hiki i kēia manawa ke kāohi a hoʻōla pono i kēia maʻi.

• E makaʻala mau i kou kino, ʻoiai kou mau umauma. Inā ʻike ʻoe i kekahi mau loli ʻē, mai hoʻowahāwahā iā lākou a e ʻimi koke i ke kōkua lapaʻau.
• E hahai pono i nā hoʻokolohua a me nā lāʻau lapaʻau a kāu kauka e ʻōlelo ai. Mai makaʻu e kamaʻilio me kāu kauka e pili ana i nā nīnau a hopohopo paha āu e loaʻa ai.
• He mea nui loa ka noho maikaʻi. ʻAʻole ʻoe hoʻokahi. Aia ka ʻohana, nā hoaaloha, nā kauka, a me nā lawelawe aʻoaʻo e kōkua iā ʻoe.

Lana ko mākou manaʻo he mea pono kēia ʻike iā ʻoe. E noho olakino!

ʻO ke kanesa o ka umauma, HER2-Positive, nā hōʻailona o ke kanesa, ka mālama ʻana i ke kanesa, ke olakino o nā wahine, nā hoʻololi genetic, mammogram