Hoʻonui ʻia ka nui o ka calcium i ke kino: No ka hyperparathyroidism anei?

Ke manaʻo pinepine nei ʻoe ua nāwaliwali a ʻeha kou mau iwi? A i ʻole ua nānā kāu kauka i kahi hōʻike koko a ʻōlelo, "Ua kiʻekiʻe iki kou pae calcium"? Malia paha ke kumu ma hope o kēia he kūlana a mākou e kamaʻilio nui ʻole ai, akā he mea nui loa ia. I kēia lā, e kamaʻilio kākou e pili ana i kēia kūlana i kapa ʻia ʻo hyperparathyroidism ma ke ʻano maʻalahi hiki iā ʻoe ke hoʻomaopopo.

He aha ka hyperparathyroidism?

I ka ʻōlelo maʻalahi, ʻo ka hyperparathyroidism ka wā e hana nui ai kekahi a ʻoi aku paha o kāu mau kelepa parathyroid a hana i ka nui o ka hormone parathyroid (PTH). ʻO kēia ke kumu e piʻi ai ka pae calcium i loko o kou koko. Kapa mākou i kēia ma ke ʻano lapaʻau he hypercalcemia .

E noʻonoʻo, ma hope o ke kelepa thyroid i loko o ko kākou ʻāʻī, aia ʻehā mau kelepa liʻiliʻi e like me ka nui o kahi hua laiki. Ua kapa ʻia kēia mau mea ʻo nā kelepa parathyroid. E like me ka pōpō e hoʻomalu ana i ka pae wai i loko o kā mākou pahu wai ma ka home, ʻo ka hana nui o kēia mau kelepa ka hoʻomalu ʻana i nā pae calcium a me phosphate i loko o ko kākou koko ma nā pae kūpono.

Penei ka hana ʻana:

• Ke hāʻule ka nui o ka calcium i ke koko, hana kēia mau kelepa i ka hormone PTH.
• Hoʻouna kēia hormone PTH i kahi hōʻailona i ko kākou mau iwi e "hoʻokuʻu i kekahi calcium i loko o ke koko."
• Hōʻike pū ia i nā puʻupaʻa e "hoʻemi i ka nui o ka calcium i hoʻokuʻu ʻia i loko o ka mimi a mālama i loko o ke kino."
• A laila, hoʻāla nā puʻupaʻa i ka wikamina D a hoʻouna iā ia i ko kākou ʻōpū . A laila, omo nā ʻōpū i ka calcium i ka meaʻai a kākou e ʻai maikaʻi ai.

He ʻōnaehana kaulike loa kēia. Eia nō naʻe, i ka hyperparathyroidism, hana nui ʻia ka hormone PTH, e hoʻokuʻu mau ana nā iwi i ka calcium, e hoʻolilo iā lākou i lahilahi a palupalu. Eia kekahi, hiki ke waiho ʻia ka calcium keu i hōʻiliʻili ʻia i loko o ke koko i loko o nā puʻupaʻa (hiki ke hana i nā pōhaku), nā kīʻaha koko, ka puʻuwai, a me nā ʻōpū ʻē aʻe, e hoʻoulu ai i nā pilikia olakino like ʻole.

He aha nā ʻano nui o kēia maʻi?

Hiki ke hoʻokaʻawale ʻia ka Hyperparathyroidism i ʻekolu mau ʻano nui, i hoʻokaʻawale ʻia e like me ke ʻano o ko lākou hanana ʻana.

He aha nā hōʻailona?

ʻAʻohe hōʻailona o ka hapa nui o ka poʻe me kēia maʻi. ʻIke pinepine ʻia nā pae calcium koko kiʻekiʻe i ka wā o kahi hoʻāʻo koko i hana ʻia no kekahi kumu ʻē aʻe. Eia nō naʻe, hiki i kekahi poʻe, ʻoiai ke kiʻekiʻe loa ko lākou pae calcium, ke ʻike i kēia mau hōʻailona:

• ʻEha iwi a me nā hono
• Nāwaliwali o nā ʻiʻo
• Ka luhi mau a me ka luhi
• Kaumaha
• Ka paʻakikī i ka noʻonoʻo ʻana i hoʻokahi mea
• Makemake nui
• Ka luaʻi a me ka luaʻi
• Ka huikau, ka poina ʻana i nā mea
• Ke manaʻo nei i ka make wai nui a me ka pono e mimi pinepine
• Ka paʻa ʻana o ka ʻōpū

He aha ke kumu o kēia?

E nānā kākou i nā kumu no nā ʻano ʻekolu a mākou i kūkākūkā ai ma mua.

Nā kumu o ka Hyperparathyroidism mua

• Adenoma: He puʻupuʻu ʻaʻole kanesa kēia e hana ʻia ana i loko o kahi kelepa parathyroid. ʻO kēia ke kumu maʻamau o ka hyperparathyroidism mua.
• Hyperplasia: ʻO kēia ka wā e nui ai kekahi o nā kelepa parathyroid.
• Ka maʻi ʻaʻai:He kumu laha ʻole loa ka maʻi ʻaʻai o nā kelepa parathyroid.

Nā kumu o ka Hyperparathyroidism Secondary

ʻO ke kumu nui o kēia, ʻo ia ka maʻi puʻupaʻa mau loa (CKD) . Ke hana pono ʻole nā ​​puʻupaʻa, piʻi aʻe nā pae phosphate i loko o ke kino a emi iho nā pae wikamina D. ʻO kēia ke kumu e emi ai nā pae calcium i loko o ke koko. No laila, no ka hoʻoponopono ʻana i kēia hemahema calcium, hana nui nā kelepa parathyroid i ka hormone PTH.

Eia kekahi, ʻo ka nele nui o ka wikamina D (ma muli o ka nele o ka lā a i ʻole nā ​​​​hemahema meaʻai) hiki ke hana i kēia.

Pehea e ʻike ai i kēia maʻi?

E hoʻolohe kāu kauka i kāu mau hōʻailona, ​​​​e nānā iā ʻoe, a kuhikuhi iā ʻoe no kekahi mau hoʻokolohua inā manaʻo lākou i kēia ʻano.

Pehea e mālama ʻia ai?

Hoʻoholo ʻia nā ʻano lapaʻau ma ke ʻano mua a lua paha kou ʻano a me ke koʻikoʻi o ka maʻi.

Lapaʻau no ka hyperparathyroidism mua

ʻO ka hopena maikaʻi loa a mau loa hoʻi no kēia, ʻo ia ka hana ʻana i kahi ʻoki kino (parathyroidectomy) e wehe i ke kelepaʻi a i ʻole nā ​​kelepaʻi hana nui. Ma hope o kēia ʻoki kino, ʻoi aku ma mua o 90% o ka poʻe e hoʻi i nā pae calcium koko maʻamau.

Inā ʻoe ma lalo o 50, loaʻa iā ʻoe nā hōʻailona, ​​​​he kiʻekiʻe loa nā pae calcium, he mau pōhaku puʻupaʻa, a he lahilahi paha kou mau iwi, e ʻōlelo maoli aku kāu kauka i ke ʻoki ʻana.

I nā hihia ʻaʻole koʻikoʻi a ʻaʻole pono ke ʻoki ʻana, e nānā mau kāu kauka i kou kūlana. A i kekahi manawa:

• ʻO Bisphosphonates: Pale kēia mau lāʻau i ka hoʻokuʻu ʻia ʻana o ka calcium mai nā iwi a hoʻoikaika iā lākou.
• Calcimimetics: Hoʻopunipuni kēia mau lāʻau lapaʻau i nā ʻāpana parathyroid i mea e hōʻemi ai i ka hana ʻana o ka hormone PTH.
• Nā loli o ke ʻano o ka nohona: E aʻo ʻia paha ʻoe e hoʻōki i ka lawe ʻana i kekahi mau lāʻau lapaʻau (e laʻa, thiazide diuretics, lithium) a hana i nā hoʻololi i ka meaʻai.

Lapaʻau no ka hyperparathyroidism lua

ʻO ke kī ma ʻaneʻi, ʻo ia ka mālama ʻana i ke kumu kumu , e like me ka kaohi ʻana i nā maʻi puʻupaʻa a me ka mālama ʻana i ka nele o ka wikamina D.

• ʻO ke kanaka me ka maʻi puʻupaʻa e pono paha i ka dialysis a i ʻole ka hoʻoili puʻupaʻa.
• Hāʻawi ʻia nā lāʻau lapaʻau e like me nā mea hoʻopaʻa phosphate e hōʻemi i nā pae phosphate i loko o ke koko.
• Hoʻohana pū ʻia ka Vitamin D a me nā lāʻau calcimimetic no kēia kumu.

Inā ʻaʻole hiki i kēia mau lāʻau lapaʻau ke kaohi i ke kūlana, pono paha ke ʻoki ʻana.