Ua haʻi aku anei kāu kauka iā ʻoe a i ʻole kekahi o kou ʻohana e hoʻomaka e lawe i kahi lāʻau i kapa ʻia ʻo Pacritinib? He mea maʻamau ka loaʻa ʻana o kekahi mau nīnau a me nā hopohopo ke lohe ʻoe e pili ana i ia ʻano lāʻau kūikawā. No laila, i kēia lā e kamaʻilio mākou e pili ana i nā mea āpau ma ke ʻano maʻalahi a aloha hoʻi, e like me ke ʻano o kēia lāʻau, pehea e hoʻohana ai, a me nā mea āu e pono ai e makaʻala.
He aha kēia lāʻau lapaʻau i kapa ʻia ʻo Pacritinib?
I ka ʻōlelo maʻalahi, ʻo Pacritinib kahi lāʻau lapaʻau i hoʻohana ʻia e mālama i kahi maʻi i kapa ʻia ʻo myelofibrosis . ʻO Myelofibrosis kahi maʻi ʻaʻai e kū mai ana i loko o ko kākou iwi iwi. Ma kēia, hoʻololi nā ʻiʻo fibrous i nā ʻōpū olakino i loko o ka iwi iwi, e hoʻopilikia ana i ka hana ʻana o ke koko.
No loko o kahi papa lāʻau lapaʻau i kapa ʻia ʻo Pacritinib nā mea hoʻopaʻa kinase . E noʻonoʻo i loko o nā pūnaewele o ko kākou kino, aia nā ʻelele liʻiliʻi (nā protein) e hōʻailona ana i nā pūnaewele e ulu a māhele. ʻO ka hana a kēia lāʻau lapaʻau, ʻo ia ke hoʻōki i ka hana o kekahi mau protein e kōkua ana i kēlā mau pūnaewele maʻi e ulu. Ua like ia me ka hoʻopau ʻana i kahi kuapo hewa i loko o kahi mīkini e holo ana. Ma kēia ʻano, ʻo ka kaohi ʻana i ka ulu ʻana o nā pūnaewele maʻi ke kumu nui o kēia lāʻau lapaʻau.
Nā mea e pono ai ʻoe e haʻi i kāu kauka ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau
Ma mua o ka hoʻomaka ʻana i kēia lāʻau lapaʻau, he mea nui loa ia e loaʻa i kāu kauka kahi kiʻi piha o kou kūlana olakino. No ka mea, ʻo kēlā ʻike e hoʻoholo ai inā kūpono kēia lāʻau lapaʻau iā ʻoe, a pehea e hāʻawi ʻia ai. Inā loaʻa iā ʻoe kekahi o kēia mau mea, e hōʻoia e haʻi i kāu kauka.
| Kūlana/maʻamau | Wehewehena |
|---|---|
| Ke kahe koko a me nā ʻūpā koko | Inā loaʻa iā ʻoe kahi maʻi kahe koko a i ʻole ka pilikia o ke koko i ka wā ma mua. |
| Maʻi puʻuwai | Inā ua loaʻa iā ʻoe ma mua kahi hōʻeha puʻuwai, hahau, a i ʻole nā maʻi puʻuwai ʻē aʻe. |
| Nā kūlana olakino ʻē aʻe | Nā kūlana e like me nā maʻi kanesa ʻē aʻe, nā maʻi ate a me nā maʻi puʻupaʻa, kahi maʻi e kū nei, ka maʻi pākī, a i ʻole ka luaʻi ʻana. |
| ʻAno nohona | Inā he mea puhi paka a puhipaka paha ʻoe. |
| Nā hoʻolālā e hiki mai ana | Inā ʻoe e hana ʻoki kino i ka wā e hiki mai ana. |
| ʻIke pilikino | Inā ʻoe e hāpai ana, e hoʻāʻo ana e hāpai, a e hānai waiū ana paha. |
| Nā maʻi ʻaleka | Inā he maʻi ʻaleka kou i ka pacritinib a i ʻole kekahi lāʻau lapaʻau ʻē aʻe, meaʻai, a mea hoʻoluʻu paha. |
Pehea e hoʻohana pono ai i ka lāʻau lapaʻau?
He mea nui loa e lawe i kāu lāʻau lapaʻau e like me ke kauoha a kāu kauka, i ka manawa kūpono.
- Loaʻa kēia lāʻau lapaʻau ma ke ʻano he capsule .
- E ale i ke capsule me ka wai . Mai nau , uhaʻi, a wili paha.
- E hoʻomaʻamaʻa i ka lawe ʻana i kāu lāʻau lapaʻau i ka manawa like i kēlā me kēia lā. Ma kēlā ʻano, ʻaʻole ʻoe e poina.
- Hiki ke lawe ʻia kēia lāʻau lapaʻau ma mua a ma hope paha o ka ʻai ʻana.
- E hoʻomau i ka lawe ʻana i ka lāʻau a hiki i ka wā e ʻōlelo ai kāu kauka e hoʻōki.
ʻŌlelo Aʻo: Ua kuhikuhi ʻia kēia lāʻau lapaʻau nou wale nō. Mai kaʻana like me kekahi no kekahi kumu.
He aha kāu e hana ai inā e poina ʻoe i kahi mahele o ka lāʻau lapaʻau?
Mai hopohopo. Inā ʻoe e poina i kahi lāʻau, e hōʻalo loa. E lawe i kāu lāʻau aʻe i ka manawa i hoʻonohonoho ʻia. Mai lawe i ʻelua mau lāʻau i ka manawa hoʻokahi e hoʻopiha ai i kahi lāʻau i poina.
He aha inā lawe nui wau i ka lāʻau lapaʻau?
Inā manaʻo ʻoe ua lawe ʻoe ma mua o ka nui i kuhikuhi ʻia, e kāhea koke aku i ke Kikowaena ʻIke Poisons National ma ka Halemai Lahui ʻo Colombo.E kelepona mai a i ʻole e hele i ka Halemai Pilikia (ETU) kokoke loa.
Nā lāʻau lapaʻau ʻē aʻe e launa pū me kēia lāʻau lapaʻau
He mea nui loa e haʻi aku i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei (me nā huaora, nā lāʻau lapaʻau lāʻau, a me nā mea hoʻohui), no ka mea, hiki i kekahi mau lāʻau lapaʻau ke launa pū me ka pacritinib, e hoʻololi ana i kona hopena a i ʻole e hoʻonui ana i kona mau hopena ʻaoʻao.
ʻOi aku ka maikaʻi o ka ʻōlelo ʻana ʻaʻole e lawe pū me ka pacritinib me nā lāʻau lapaʻau ma lalo nei.
- ʻO kekahi mau lāʻau antiviral no ka maʻi HIV a i ʻole AIDS
- ʻO kekahi mau lāʻau antibiotic, e like me ka clarithromycin a me ka erythromycin
- Nā lāʻau lapaʻau no nā maʻi fungal, e like me ketoconazole a me itraconazole
- Nā lāʻau antiepileptic e like me ka carbamazepine a me ka phenytoin
- ʻO Rifampin
- ʻO ka huahana lāʻau wort a St. John
Eia kekahi, hiki iā ia ke launa pū me nā lāʻau lapaʻau ʻē aʻe e hiki ai ke hoʻololi i ka puʻuwai puʻuwai (e hoʻolōʻihi i ka wā QT). ʻAʻole i piha kēia papa inoa. No laila e hōʻoia e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei.
Nā mea e makaʻala ai i ka wā e lawe ai i ka lāʻau lapaʻau
- Nā nānā mau ʻana: E noi aku kāu kauka iā ʻoe e hele pinepine i ke keʻena lapaʻau e nānā i kou kūlana. E kauoha pū ʻo ia i nā hoʻāʻo koko (hana koko). Mai poina i kēia mau mea a hana mau.
- Ka pilikia o ke kahe koko: Hiki i kēia lāʻau lapaʻau ke hoʻonui iki i kou pilikia o ke kahe koko a i ʻole ka maʻalahi o ka palapū. E haʻi koke i kāu kauka inā ʻike ʻoe i kekahi kahe koko ʻē (e laʻa, mai kou ʻāʻī, ihu) a i ʻole ka palapū nui.
- Ka pilikia o ka maʻi: Hiki i kēia lāʻau lapaʻau ke hōʻemi iki i ka hana o kāu ʻōnaehana pale. No laila, ʻoi aku ka nui o ka pilikia o ka loaʻa ʻana o nā maʻi. Inā ʻike ʻoe i nā hōʻailona e like me ke kuni, ke anu, ka ʻeha o ka puʻu, a me ke kuni, mai hoʻōla ponoʻī a kāhea aku i kāu kauka. E hoʻāʻo e noho mamao mai nā wahi i loaʻa ai ka poʻe maʻi.
- Ka pilikia o ke kanesa: Aia kekahi mau hōʻike e hiki i kēia lāʻau lapaʻau ke hoʻonui iki i ka pilikia o kekahi mau ʻano kanesa ʻē aʻe. E kamaʻilio me kāu kauka e pili ana i kēia no ka ʻike hou aku.
- Nā hopena i ka momona: Hiki i kēia lāʻau lapaʻau ke hoʻopilikia i ka momona o nā kāne. Inā ʻoe e manaʻolana ana e loaʻa nā keiki, e kūkākūkā i kēia me kāu kauka ma mua o ka hoʻomaka ʻana i ka lāʻau.
- Ka hānai waiū: Mai hānai i kāu pēpē i ka waiū i ka wā e lawe ana i kēia lāʻau lapaʻau a no 2 mau pule ma hope o ka hoʻōki ʻana i ka lāʻau lapaʻau.
Nā hopena ʻaoʻao e hiki mai ana ma muli o ka lāʻau lapaʻau
E like me nā lāʻau lapaʻau āpau, hiki i kēia lāʻau lapaʻau ke hana i nā hopena ʻaoʻao i kekahi poʻe. Eia naʻe, ʻaʻole loaʻa i nā kānaka a pau. Aia ma lalo kekahi o nā hopena ʻaoʻao hiki ke loaʻa.
| Nā hopena ʻaoʻao koʻikoʻi e pono e hōʻike koke ʻia i kāu kauka | |
|---|---|
| Nā hopena maʻi ʻaleka | ʻŌhūhū ʻili, maneʻo, pehu o ka maka, nā lehelehe a i ʻole ke alelo. |
| Ke kahe ʻana o ke koko | ʻO ka ʻōpala ʻeleʻele a koko paha, ka luaʻi ʻana i kahi mea e like me ke kofe lepo, nā kiko ʻulaʻula ma ka ʻili, ke kahe koko ʻokoʻa mai nā maka/ʻāʻī/ihu. |
| ʻAʻa koko | ʻEha ka umauma, ka hanu pōkole, ka ʻeha o ka wāwae, ka pehu ʻana, a i ʻole ka mehana. |
| Nā Hōʻailona o ka Hōʻeha Puʻuwai | Paʻakikī ka hanu ʻana, ʻeha a ʻūmiʻi paha ma ka umauma/ʻāʻī/lima, luhi nui. |
| Nā loli i ka helu o ka puʻuwai | Pōniuniu, puʻuwai wikiwiki a ʻano ʻē paha, manaʻo nāwaliwali. |
| Nā hōʻailona o ka hahau ʻana | Nā loli o ka ʻike, huikau, paʻakikī i ka ʻōlelo ʻana a i ʻole ka hoʻomaopopo ʻana, mae koke ka hanu, paʻakikī i ka hele wāwae. |
| ʻĒ aʻe | Ka maʻi palahē nui a i ʻole ka luaʻi ʻana, nā hōʻailona o ka maʻi (kuni, anuanu). |
| Nā mea i maʻa mau ʻole i ka nui, akā pono e hōʻike ʻia i ke kauka inā hoʻomau lākou | |
| Pehu ʻana | Ka pehu ʻana o nā kuʻekuʻe wāwae, nā wāwae, a i ʻole nā lima. |
Leka Lawe-Home
- He lāʻau lapaʻau ʻo Pacritinib e pono e hoʻohana ʻia me ke akahele nui, ma lalo wale nō o ke aʻo ʻana a ke kauka.
- Ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau, e haʻi i kāu kauka e pili ana i kou mau kūlana olakino a me nā lāʻau lapaʻau ʻē aʻe āu e lawe nei.
- Inā ʻike ʻoe i ke kahe koko ʻē, nā hōʻailona o ka maʻi, a i ʻole nā hopena koʻikoʻi ʻē aʻe i ka wā e lawe ana i ka lāʻau lapaʻau, e ʻimi koke i ke kōkua lapaʻau.
- Mai kaʻana like i kāu lāʻau lapaʻau i kuhikuhi ʻia me nā poʻe ʻē aʻe no kekahi kumu.
- Inā makemake ʻoe e hānai i kahi keiki a hoʻolālā paha e hāpai, e kamaʻilio me kāu kauka ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau.
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