Ua pehu kou mau wāwae a ua ʻāʻī paha ka ʻili? E aʻo kākou e pili ana i kēia (Pretibial Myxedema)!

Ua ʻike anei ʻoe i ka pehu koke ʻana o ka ʻili ma kou mau wāwae, ʻoi aku hoʻi ma lalo o nā kuli, a i kekahi manawa ua loli ke kala? A i ʻole ke ʻano o ka ʻili ʻalani ma kekahi mau wahi? Inā loaʻa iā ʻoe kēia mau hōʻailona, ​​​​loaʻa paha iā ʻoe kahi maʻi i kapa ʻia ʻo Pretibial Myxedema, a mākou e kamaʻilio nei i kēia lā.

He aha kēia (Pretibial Myxedema)? E hoʻomaopopo maʻalahi kākou!

I ka ʻōlelo maʻalahi, ʻo Pretibial Myxedema, i kapa ʻia i kekahi manawa ʻo Graves' Dermopathy, he ʻano ia o ka maʻi Graves, kahi maʻi e hoʻopilikia ai i ko mākou ʻili. Hoʻokumu ʻia ia e ka hōʻiliʻili ʻana o nā kalapona a me nā kō, a ʻoi aku ka pololei, glycosaminoglycans a i ʻole mucopolysaccharides, i loko o nā papa hohonu o ko mākou ʻili. Hōʻiliʻili nui kēia mau mea ma nā wāwae haʻahaʻa, ma lalo o nā kuli. ʻO kēia ka manawa e pehu ai nā wāwae, lilo ka ʻili i puʻupuʻu, a lilo ka ʻili i unahi (scaling plaques). He aha ka manaʻo o nā huaʻōlelo "Pretibial" a me "Myxedema"?

• "Pretibial": Pili kēia i ka iwi nui ma ka ʻaoʻao o ko kākou wāwae ma lalo o ke kuli, ʻo ia hoʻi ke alo o ka `(tibia)`. Inā mākou e ʻōlelo ma ka ʻōlelo Sinhala, ua like ia me "ma mua o ka iwi ʻūhā".
• "Myxedema": ʻO ke ʻano kēia o ka pehu ʻana o nā ʻiʻo ma lalo o ko mākou ʻili.

ʻO wai ka mea i hoʻopilikia nui ʻia e kēia kūlana?

(Pretibial Myxedema) ʻOiai hiki i kekahi ke loaʻa iā ia, ʻoi aku ka nui o ka poʻe e loaʻa iā ia. ʻO lākou:

• Nā kānaka me ka maʻi ʻo Graves: ʻO kēia ka mea nui e hopohopo nei.
• ʻO ka poʻe me nā pilikia thyroid: ʻO ia hoʻi nā kūlana e like me `(Hypothyroidism)` (haʻahaʻa ka hormone thyroid) a i ʻole `( Hyperthyroidism )` (kiʻekiʻe ka hormone thyroid ).
• ʻO nā kānaka me ka maʻi maka koʻikoʻi: Hoʻopili pinepine ʻia kēia me ka maʻi ʻo Graves.
• ʻO nā kānaka ma waena o 40 a me 60 mau makahiki.
• Nā wāhine: ʻOi aku ka maʻamau o kēia ʻano maʻi i nā wāhine ma mua o nā kāne.

E noʻonoʻo, ua loaʻa i kou hoalauna, ʻo ʻAnakē Susila, nā pilikia thyroid no kekahi manawa. Ua ʻike koke ʻo ia ua pehu ka ʻāpana ma lalo o nā kuli o kona mau wāwae, ua ʻulaʻula iki ka ʻili, a ua like ia me nā puʻupuʻu liʻiliʻi i ka wā e hoʻopā ʻia ai. I ka wā mua, ua manaʻo ʻo ia he mea ia no ka hoʻoikaika kino. Akā i kona hōʻike ʻana i ke kauka, ua ʻike ʻo ia he Pretibial Myxedema paha ia.

He aha nā ʻano nui o ka Pretibial Myxedema?

ʻEhā ʻano nui o kēia maʻi. Hiki ke ʻokoʻa iki nā hōʻailona e like me ia: 1. Hoʻolaha: ʻO kēia ke ʻano maʻamau. Hōʻike ʻia kēia e ka edema ʻaʻole e piʻi i ka wā e kaomi ʻia ai ka ʻili i ka ʻili. 2. Plaque:Ma waho aʻe o ka pehu ʻana, aia nā palaki mānoanoa, piʻi aʻe, a ʻōpala ma ka ʻili. 3. Nodular: Ma waho aʻe o ka pehu ʻana, aia nā nodules paʻakikī ma lalo o ka ʻili. 4. Elephantiasis: ʻO kēia ke ʻano kakaikahi loa. I kēia ʻano, hōʻiliʻili ka wai lymphatic ma lalo o ka ʻili, e hāʻawi ana i ka ʻili i kahi ʻano wart a ʻāʻī.

He aha nā hōʻailona o (Pretibial Myxedema)? E ʻike pono kākou iā lākou!

Inā loaʻa iā ʻoe kēia ʻano, hiki iā ʻoe ke ʻike i hoʻokahi a ʻoi aku paha o kēia mau hōʻailona:

• Pehu: ʻOi aku ka nui a me ka pehu o ka ʻili ma kou wāwae ma mua o ka lā ma mua.
• Nā puʻupuʻu paʻakikī ma lalo o ka ʻili: Hiki ke ʻike ʻia kēia mau mea ke hoʻopā ʻoe iā lākou me kou lima.
• Lilo kekahi mau wahi o ka ʻili i mānoanoa a lilo e like me nā ʻōpala: e like me nā unahi iʻa.
• ʻIke ka ʻili a me nā follicle lauoho i kahi ʻano ʻālohilohi a like me ka waxy: Hiki ke nānā aku me ka ʻili ʻalani .
• Hoʻololi ke kala o ka ʻili : hiki ke ʻano mai ka melemele a me ka ʻalani a i ka ʻeleʻele, ka ʻulaʻula, a me ka poni.
• Aia ka nui o ka hou ʻana a i ʻole ka ulu nui ʻana o ka lauoho ma nā wahi i hoʻopilikia ʻia.
• ʻEha a maneʻo paha ka ʻili.

I ka wā mua, hoʻomaka paha ke ʻano me he puʻupuʻu paʻakikī ma ka ʻili. Hiki i kēia puʻupuʻu ke ulu nui aʻe i ka hala ʻana o ka manawa, a i ʻole e hui pū me nā puʻupuʻu ʻē aʻe.

Ma hea ma ke kino e hoʻopilikia nui ai kēia mau hōʻailona?

ʻO nā hōʻailona maʻamau o ka Pretibial Myxedema:

• Ma nā wāwae ma lalo o nā kuli.
• Ma nā kapuwaʻi.
• ʻO nā ʻūhā ma ka ʻāpana ʻūhā.

I kekahi manawa hiki ke hoʻololi ʻia nā loli o ka helehelena e ka maʻi ʻo Graves a i ʻole kahi maʻi thyroid, akā he pilikia ʻokoʻa kēlā.

No ke aha mākou e loaʻa ai (Pretibial Myxedema)? He aha nā kumu?

ʻOiai ʻaʻole i maopopo loa ke kumu kikoʻī o kēia, ua puka mai kekahi mau kumu mai ka noiʻi ʻana. ʻO ke kumu nui o kēia, ʻo ia ka hōʻiliʻili ʻana o nā hui kō `(glycosaminoglycans a i ʻole mucopolysaccharides)` a mākou i ʻōlelo ai ma mua i loko o nā papa `(dermis)` a me `(hypodermis)` o ka ʻili. Akā no ke aha e hōʻiliʻili ai ia e like me kēlā? 1. He kaʻina hana ʻōnaehana pale `(Autoimmune response)`: I ka ʻōlelo maʻalahi, hoʻomaka ka ʻōnaehana pale ponoʻī o ko mākou kino e hana kūʻē iā mākou. Ma kēia, hōʻailona kā mākou ʻōnaehana pale i kā mākou mau cell e hana i `(antibodies)` e kūʻē i nā hormones thyroid. ʻO kēia mau `(antibodies)` ke kumu o nā cell e hana i kahi mea i kapa ʻia ʻo `(glycosaminoglycans)` i ka nui. 2. Hoʻoulu ʻana o nā cell (T lymphocyte): ʻO `(T lymphocytes)` kahi ʻano cell kūikawā i loko o kā mākou ʻōnaehana pale. Hele kēia mau cell i loko o ka ʻiʻo ʻili a hoʻokuʻu i nā protein ʻelele i kapa ʻia ʻo `(cytokines)`. ʻO kēia mau cytokines ke kumu o nā cell e hana i nā nui o nā glycosaminoglycans. 3. Pane ʻeha:E noʻonoʻo he ʻeha kou ma kou wāwae haʻahaʻa, ma ka ʻāpana pretibial. Inā loaʻa iā ʻoe ka hypothyroidism, hiki i nā pūnaewele pale a me nā protein ke hōʻiliʻili ma kahi o ka ʻeha. ʻO kēia no ka mea ke kāohi nei nā hormones thyroid i ka hōʻiliʻili ʻana o kēia mau hui i loko o nā ʻiʻo. Ke nele nā ​​hormones, nalowale kēlā mana.

Pehea e ʻike ai ke kauka i ka Pretibial Myxedema?

Ke ʻike ʻoe i ke kauka, e nīnau mua ʻo ia iā ʻoe e pili ana i kāu mau hōʻailona a me nā kūlana olakino ʻē aʻe āu e loaʻa ai (`(mōʻaukala lapaʻau)`). A laila e nānā lākou iā ʻoe (`(hoʻokolokolo kino)`). No ka hōʻoia inā he (Pretibial Myxedema) kēia, hiki i ke kauka ke hana i nā hoʻokolohua aʻe:

• Hoʻāʻo koko: E nānā i kāu pae hormone thyroid .
• ʻO ka biopsy ʻili: Hiki ke hoʻohana ʻia kēia e hoʻoholo ai inā loaʻa ke kūlana a e ana i nā pae o glycosaminoglycans i loko o ka ʻili.

Aia kekahi lāʻau lapaʻau no kēia? He aha ka mea hiki ke hana ʻia?

ʻO ka hapa nui o ka manawa, ʻo nā hōʻailona o Pretibial Myxedema he hoʻonaninani wale nō, no laila ʻaʻole pono mau ka mālama ʻana. ʻO ia hoʻi, ʻaʻole lākou e hōʻeha nui . Eia nō naʻe, inā ʻoluʻolu ʻole ʻoe i ke ʻano a i ʻole he mau hōʻailona ʻē aʻe (mani, ʻeha), aia nā lāʻau lapaʻau i loaʻa.

• Ke komo ʻana i nā kāʻei hoʻopaʻa a i ʻole nā ​​​​kāmaʻa: Hiki i kēia ke hōʻemi i ka pehu.
• Nā kirīmi a i ʻole nā ​​​​​​mea ʻaila topical: Kāohi i ka maneʻo a me ka pehu.
• Nā lāʻau lapaʻau a me nā inikini waha a me waho: No ka hōʻemi ʻana i nā puʻupuʻu ma lalo o ka ʻili a i ʻole e hōʻemi i nā loli i ke ʻano.
• Ke mālama ʻana i ka maʻi Graves a i ʻole ke ʻano Thyroid: ʻO kēia ka mea nui loa . Ke mālama ʻia ke kumu kumu, hoʻomaikaʻi pinepine nā hōʻailona o Pretibial Myxedema.
• Plasmapheresis: He ʻano hana paʻakikī iki kēia. Pili ia i ka wehe ʻana i ka ʻāpana wai o ke koko (plasma), hoʻololi i nā hunaola koko ʻulaʻula a me keʻokeʻo a me nā platelets i loko o kahi wai hou, a laila hoʻihoʻi hou iā lākou i loko o ke kino. ʻAʻole hiki i nā mea āpau ke hana.

He mea nui: ʻOiai hiki i ke ʻoki kino ke wehe i nā nodules subcutaneous, ʻaʻole ia i ʻōlelo pinepine ʻia. ʻO kēia no ka mea, i ka wā e ho'ōla ai ka ʻili ma hope o ke ʻoki kino, ʻoi aku ka nui o ka manawa e hoʻi hou ai nā nodules ma kahi o ka ʻeha. ʻO kēia no ka mea mālama ke kino i kahi ʻoki kino me he "ʻeha."

He aha nā lāʻau lapaʻau i hāʻawi ʻia no ka Pretibial Myxedema?

Hiki i kāu kauka ke hāʻawi iā ʻoe i nā lāʻau lapaʻau e like me kēia e kōkua i ka hōʻemi ʻana i nā hōʻailona o kēia ʻano:

• (Nā Corticosteroids):ʻO kēia nā lāʻau lapaʻau topical e kōkua ai i ka hoʻēmi ʻana i ka pehu, ka mumū, a me ka maneʻo.
• (Pentoxifylline): He lāʻau lapaʻau waha kēia e hoʻomaikaʻi ai i ke kahe koko ma nā wāwae.
• (Octreotide): He inikini kēia. Hiki iā ia ke hoʻēmi i ka nui o nā puʻupuʻu ma lalo o ka ʻili.
• (Rituximab): He hoʻokomo intravenous nō hoʻi kēia. Kōkua ia i nā antibodies o ko mākou kino e hana pono.
• ʻO ka immunoglobulin intravenous (IVIG): He lāʻau lapaʻau kēia i hāʻawi ʻia i loko o kahi aa. Hoʻomaikaʻi ia i ka hana o nā antibodies i loko o ka ʻōnaehana pale.

Ma mua o ka hoʻomaka ʻana i kahi lāʻau lapaʻau hou, e kamaʻilio me kāu kauka e pili ana i kona mau hopena ʻaoʻao, pehea ka lōʻihi o kou lawe ʻana, a inā paha e hoʻopilikia ia i nā lāʻau lapaʻau ʻē aʻe āu e lawe nei.

Pehea ka wikiwiki o koʻu ho'ōla ʻana ma hope o ka lāʻau lapaʻau?

ʻO ka lōʻihi o ka manawa e loaʻa ai iā ʻoe nā hōʻailona o Pretibial Myxedema e loli ma muli o ke koʻikoʻi o kou kūlana. Me ka mālama ʻana, hiki ke hoʻomaikaʻi ʻia nā hōʻailona i loko o kekahi mau pule a i kekahi mau mahina. Me ka ʻole o ka mālama ʻana, hiki i kekahi manawa ke hala i kekahi mau makahiki no ka hoʻoponopono ʻana o ke kūlana iā ia iho. Akā e hoʻomanaʻo, inā loaʻa iā ʻoe kahi ʻeha i kou mau wāwae haʻahaʻa, hiki i ke kūlana ke hoʻi hou.

Aia kekahi mau ala e pale aku ai i kēia (Pretibial Myxedema) mai ka hana ʻana?

ʻAʻohe ala e pale loa ai i kēia mai ka hana ʻana, akā hiki iā ʻoe ke hana i kēia mau mea e hōʻemi ai i kou pilikia:

• Mai hoʻohana i nā huahana paka.
• Inā loaʻa iā ʻoe nā maʻi e hoʻopilikia i kāu hana thyroid, e mālama pono iā lākou.
• E komo i nā kāʻei hoʻopaʻa a i ʻole nā ​​​​kāmaʻa paʻa ma kou mau wāwae.

A pehea inā loaʻa iaʻu kēia maʻi pū kekahi? He mea anei ia e makaʻu ai?

ʻO ka wānana no ka poʻe me Pretibial Myxedema ma ke ʻano laulā he maikaʻi. Inā pili wale kāu mau hōʻailona i kou helehelena, ʻaʻole paha ʻoe e pono i ka lāʻau lapaʻau. Inā he hihia iki kou, e nalo wale ia ma kāna iho. Inā ʻoi aku ka koʻikoʻi o kāu hihia, maikaʻi ka wānana, akā hiki ke hala i kekahi mau makahiki e hoʻōla piha ai.

Pono anei au e ʻike i ke kauka?

Hiki i ka Pretibial Myxedema ke hoʻi hou mai ma hope o kona ho'ōla ʻia ʻana, ʻoiai inā he ʻeha kou ma kou wāwae haʻahaʻa. No laila, inā ua emi iho kou mau hōʻailona a laila hoʻi hou mai, e kamaʻilio me kāu kauka. Eia kekahi, inā loaʻa iā ʻoe ka ʻeha a i ʻole ka ʻūlū nui, e ʻike pono i ke kauka.

He aha nā nīnau e pono iaʻu e nīnau aku i ke kauka?

He manaʻo maikaʻi e hoʻomākaukau i kekahi mau nīnau e like me kēia ke hele ʻoe i ke kauka:

• Hiki iaʻu ke hoʻohana i nā kāʻei hoʻopaʻa e kōkua ai me ka Pretibial Myxedema?
• Pono anei au i ka lāʻau no ka Pretibial Myxedema?
• Ke kumu ʻia nei koʻu mau hōʻailona e kahi maʻi thyroid?
• Pehea e mālama ai i koʻu ʻili i hoʻopilikia ʻia e ka Pretibial Myxedema?

He aha ka ʻokoʻa ma waena o (Pretibial Myxedema) a me (Erythema Nodosum)?

Hoʻopilikia kēia mau kūlana ʻelua i ko mākou ʻili, ʻoiai ka ʻili ma ko mākou mau wāwae ma lalo o nā kuli. Eia nō naʻe, aia nā ʻokoʻa o nā hōʻailona:

• (Pretibial Myxedema): Hoʻoulu kēia i ka pehu a me nā ʻōpala ʻālohilohi, mānoanoa, e like me ka coral.
• (Erythema Nodosum): Hoʻoulu kēia i ka pehu a me nā puʻupuʻu liʻiliʻi a ʻeha hoʻi ma ka ʻili.

ʻO ka mea hope loa, nā mea e hoʻomanaʻo ai

ʻO ka Pretibial Myxedema kahi maʻi i ʻole e pono ai ka lāʻau lapaʻau. I ka hapa nui o nā hihia, e nalo wale ia. Eia nō naʻe, inā hoʻopilikia nā loli i ke ʻano iā ʻoe, aia nā lāʻau lapaʻau i loaʻa. Hiki i ke komo ʻana i nā kāmaʻa compression ke kōkua i ka hōʻemi ʻana i ka pehu a hoʻoluʻolu iā ʻoe. Inā loaʻa iā ʻoe ka ʻeha a i ʻole ka ʻāʻī nui ma kou mau wāwae haʻahaʻa, e kamaʻilio me ke kauka. Eia kekahi, pili pinepine kēia maʻi me ka maʻi Graves a me nā pilikia thyroid, no laila he mea nui e makaʻala i kēlā mau mea.

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