Maopopo maoli iaʻu ka makaʻu, ka hopohopo, a me ke kānalua āu a i ʻole kāu mea aloha e manaʻo ai ma hope o ka lohe ʻana i kahi hōʻailona maʻi kanesa. Ke ʻōlelo kāu kauka i kahi lāʻau i kapa ʻia ʻo "R-CHOP," nui paha kāu mau nīnau e like me, "He aha ia?" a i ʻole "He aha ka mea e hana ʻia?" E ʻoluʻolu, mai hopohopo. I kēia lā, e kamaʻilio kākou e pili ana i ke ʻano o R-CHOP, pehea e hana ai, a pehea e hiki ai iā ʻoe ke hoʻokele i kēia lāʻau ma nā ʻōlelo maʻalahi a maopopo.
I nā huaʻōlelo maʻalahi, he aha ʻo R-CHOP?
ʻO R-CHOP kahi hui pū ʻana o ʻelima mau lāʻau lapaʻau i hoʻohana ʻia e luku i nā hunaola kanesa . He lāʻau lapaʻau maʻamau loa ia no kahi ʻano kanesa i ʻike ʻia ʻo non-Hodgkin lymphoma . Hōʻike kēlā me kēia leka ma ka inoa i kekahi o nā lāʻau lapaʻau i hoʻohana ʻia i kēia regimen.
| Leka | Lāʻau lapaʻau a me ka hana |
|---|---|
| R | Rituximab: He lāʻau lapaʻau i hoʻolālā ʻia kēia. Hoʻopaʻa ia i kahi protein kikoʻī i loaʻa ma ka ʻili o nā hunaola kanesa, e kōkua ana i kāu ʻōnaehana pale e ʻike a luku maʻalahi iā lākou. |
| C | Cyclophosphamide: He lāʻau chemotherapy kēia i hoʻolālā ʻia e pepehi i nā pūnaewele e māhele wikiwiki ana, e like me nā pūnaewele kanesa. |
| H | ʻO Doxorubicin hydrochloride (Hydroxydaunomycin): ʻO kekahi lāʻau chemotherapy ikaika ʻē aʻe. |
| ʻO | ʻO Vincristine sulfate (Oncovin): He lāʻau lapaʻau chemotherapy i hoʻohana ʻia e hoʻopilikia i ka ulu ʻana o nā cell cancer. |
| P | ʻO Prednisone: He corticosteroid e kōkua i ka luku ʻana i nā hunaola kanesa a hoʻemi i ka pilikia o nā hopena maʻi i nā lāʻau lapaʻau R-CHOP ʻē aʻe. |
E like me kāu e ʻike ai, ua komo pū kēia lāʻau lapaʻau me nā lāʻau chemotherapy a me kahi lāʻau lapaʻau e kuhikuhi ana i ka ʻōnaehana pale (Rituximab). Ma muli o kēia, kapa pinepine nā kauka iā ia he "immuno-chemotherapy."
He aha nā maʻi kanesa e hoʻohana ʻia ai ʻo R-CHOP?
Hoʻohana nui ʻia kēia lāʻau lapaʻau no ka lymphoma non-Hodgkin . He kūpono loa ia no ke ʻano maʻamau, ʻo ka lymphoma B-cell nui diffuse (DLBCL) . Eia kekahi, hiki ke hoʻohana ʻia ʻo R-CHOP no nā ʻano maʻi ʻē aʻe, me:
- ʻO ka lymphoma follicular holomua
- ʻO ka lymphoma cell mantle
- ʻO ka macroglobulinemia o Waldenstrom
I kekahi mau hihia, hiki i kāu kauka ke hoʻoholo e hoʻokomo iā R-CHOP ma ke ʻano he ʻāpana o kahi hoʻolālā lapaʻau ākea no nā ʻano maʻi ʻē aʻe.
Pehea e lawelawe ʻia ai ka lāʻau lapaʻau?
Hāʻawi ʻia ʻo R-CHOP i loko o nā "pōʻaiapuni." ʻO ka maʻamau, ʻekolu pule (21 mau lā) ka lōʻihi o kēlā me kēia pōʻaiapuni a he ʻelua mau pae:
1. Nā Lā Lapaʻau: Nā lā e loaʻa ai iā ʻoe kāu lāʻau lapaʻau.
2. Nā Lā Hoʻōla: ʻO ka manawa i ʻae ʻia ai kou kino e ho'ōla a hoʻōla ma mua o ke kaʻina hana aʻe.
Nā Lā Lapaʻau
Hiki ke hāʻawi ʻia ka lāʻau lapaʻau i loko o kekahi mau lā. Lawe pinepine ʻia ʻo Prednisone ( he corticosteroid ) ma ke ʻano he pila. Hoʻokele ʻia nā lāʻau lapaʻau ʻē aʻe ʻehā ma o kahi infusion intravenous (IV). E kipa aku ʻoe i kahi haukapila a i ʻole ke keʻena lapaʻau, kahi e hiki ai iā ʻoe ke noho ʻoluʻolu i ka wā e hāʻawi ʻia ai ka lāʻau lapaʻau ma o kahi aʻa i kou lima, lima, a i ʻole ka umauma. Inā lawelawe ʻia ka lāʻau lapaʻau ma o ka umauma, hiki ke waiho ʻia kahi mea liʻiliʻi i kapa ʻia ʻo "port-a-cath" (chemo port) ma lalo o kou ʻili.
I ka lā mua o ka lāʻau lapaʻau, e loaʻa iā ʻoe nā lāʻau lapaʻau e pale aku ai i ka nausea a me nā hopena allergies. I ka hoʻomaka ʻana iā Rituximab , he mea maʻamau ke manaʻo iki i ka poniuniu a mehana paha; ʻo ia ke kumu e hoʻomaka mālie ai ka hoʻokomo ʻana. E loaʻa iā ʻoe ka lāʻau lapaʻau e hoʻokele i kēia mau hōʻailona, no laila ʻaʻohe pono e hopohopo.
Nā Lā Hoʻōla
Ma hope o kou mau lā lapaʻau, maʻamau he 16 mau lā o ka ho'ōla ʻana. Ma muli o ka ikaika o R-CHOP, he mea maʻamau loa ke manaʻo luhi a me ka luhi . I loko o kēia manawa, paipai ikaika wau e noi i ka ʻohana a i ʻole nā hoaaloha no ke kōkua me kāu hana maʻamau i kēlā me kēia lā.
Inā lawa kou ikehu, e paipai paha kāu kauka i nā hana māmā, e like me ka hele wāwae. He mea nui nō hoʻi ka noho ʻana i ka wai a me ka ʻai ʻana i ka meaʻai kaulike a momona no kou hoʻōla ʻana.
He aha nā pilikia a me nā hopena ʻaoʻao?
E like me nā lāʻau lapaʻau āpau, hiki i ka R-CHOP ke loaʻa nā hopena ʻaoʻao. Eia nō naʻe, e hoʻomanaʻo e hāʻawi kāu hui lapaʻau Nirogi Lanka i nā lāʻau lapaʻau e pale aku ai a hoʻokele pono paha i kēia mau mea. ʻOkoʻa nā hopena ʻaoʻao mai kēlā kanaka a kēia kanaka; ʻaʻole e ʻike nā kānaka a pau iā lākou āpau. E nānā kākou i nā hopena ʻaoʻao maʻamau āu e hālāwai ai.
| Ka hopena ʻaoʻao maʻamau | Nā mea āu e ʻike ai a hana ai |
|---|---|
| Mimi ʻUlaʻula/Pōniʻoniʻo | He ʻulaʻula maoli ko Doxorubicin. E ʻike paha ʻoe he ʻulaʻula a poni paha kou mimi a hiki i 48 mau hola ma hope o ka mālama ʻana. He mea maʻamau loa kēia, no laila e ʻoluʻolu, mai hopohopo. |
| Ka luaʻi a me ka luaʻi | ʻOiai me ka lāʻau lapaʻau anti-nausea, hiki nō iā ʻoe ke ʻike i nā manaʻo liʻiliʻi o ka maʻi. E hoʻāʻo e ʻai i nā meaʻai liʻiliʻi a pinepine ma mua o nā mea nui, ʻaila, a ʻala paha. |
| Poho lauoho | He hopena maʻamau kēia o ka chemotherapy. Hiki iā ʻoe ke hoʻomaka e nalowale kou lauoho i loko o ʻekolu pule o kāu kau mua. Eia nō naʻe, e hoʻomanaʻo e ulu hou kou lauoho ma hope o ka pau ʻana o kāu lāʻau lapaʻau. |
| ʻĀʻī a me ke kuni | Hiki i ka chemotherapy ke hoʻohaʻahaʻa i kāu helu koko keʻokeʻo, e hoʻonui ana i kou pilikia o ka maʻi. Hiki ke kuhikuhi ʻia iā ʻoe nā inikini G-CSF e kōkua i ka hoʻonui ʻana i kāu helu. Akā naʻe, inā loaʻa iā ʻoe ke kuni, e kelepona koke aku i kāu kauka. |
| Luhi | Hiki i ka lāʻau lapaʻau ke alakaʻi i ka anemia ma muli o ka emi ʻana o ka helu o nā hunaola koko ʻulaʻula. E hoʻolohe i kou kino a hoʻomaha ke luhi ʻoe. Mai kānalua e noi i ke kōkua me kāu mau hana o kēlā me kēia lā. |
| ʻO ka palapū/kahe koko maʻalahi | Hiki paha kēia ma muli o ka emi ʻana o kāu helu platelet. E mālama pono e pale i nā ʻeha a e hoʻomaopopo i kāu kauka inā ʻike ʻoe i ka palapū i wehewehe ʻole ʻia. |
| ʻO ka mae/ʻūlū ma nā lālā | Ua kapa ʻia kēia ʻano he peripheral neuropathy. E ʻoluʻolu e hoʻomaopopo i kāu kauka inā loaʻa iā ʻoe kekahi ʻano mae, ʻūlū, a i ʻole ke kuni ʻana i kou mau lima a i ʻole kou mau wāwae. |
E hoʻomanaʻo mau: hiki i ke kuni ke hōʻailona o kahi maʻi koʻikoʻi. Inā he 100.4°F (38°C) a ʻoi aku paha kou mahana, e kelepona koke aku i kāu kauka a i ʻole e hele i ka keʻena pilikia kokoke loa.
Eia kekahi, hiki iā ʻoe ke loaʻa nā ʻeha waha, nā ʻulaʻula ʻili, nā ʻeha poʻo, ka paʻa ʻana o ka ʻōpū a i ʻole ka maʻi diarrhea, ka ʻeha puʻuwai, ka hiamoe ʻole, a i ʻole nā loli o ke ʻano. E kūkākūkā ākea i kekahi o kēia mau hōʻailona me kāu hui lapaʻau.
Āhea wau e hoʻokaʻaʻike aku ai i kaʻu kauka?
E hoʻomaopopo i kāu mea mālama ola kino inā loaʻa iā ʻoe kekahi mau hōʻailona hou a inā e koʻikoʻi nā mea i loaʻa i ka wā o kāu mālama ʻana. He mea nui loa ia e hōʻike koke i kekahi kuni.
I ke kūlana o nā pilikia, e like me ka pōkole o ka hanu a i ʻole ka ʻeha nui o ka umauma, e hele pololei i ka lumi pilikia o ka haukapila kokoke loa.
Pehea e hiki ai iaʻu ke maʻalahi i kēia wā lapaʻau?
ʻAʻole ʻoe hoʻokahi i kēia huakaʻi. Eia kekahi mau ala e hoʻokele ai i kēia manawa:
- E Noho Mālama: E kamaʻilio akāka me kāu kauka e pili ana i kāu hoʻolālā lapaʻau a me nā hopena ʻaoʻao. Mai kānalua e nīnau.
- E noi i ke kōkua: E hilinaʻi i nā hoaaloha a me ka ʻohana no nā hana o ka hale, nā meaʻai, a i ʻole ka halihali i kāu mau manawa i hoʻonohonoho ʻia.
- ʻAi a Hoʻomaʻemaʻe i ka Wai: E kālele i ka meaʻai momona a mālama i ka wai maikaʻi.
- E ʻimi i ke kākoʻo: E nīnau i kāu kauka e pili ana i nā hui kākoʻo no nā poʻe e kū nei i nā lāʻau lapaʻau like. Hiki i ka haʻi ʻana i kāu mau ʻike ke hāʻawi i ka hōʻoluʻolu nui i ka naʻau.
Hiki ke paʻakikī nā pule i hala ma ke ʻano o R-CHOP, no ka mea, he lōʻihi paha nā lā lapaʻau a ʻo ka mālama ʻana i nā hopena ʻaoʻao e pono ai ka mālama hou aku. Eia nō naʻe, no nā mea he nui, ʻo nā hopena i loaʻa ma o R-CHOP e hoʻolilo i kēia hoʻoikaika i mea kūpono. ʻO ka hui pū ʻana o kēia mau ʻano lāʻau lapaʻau ʻekolu (ka lāʻau lapaʻau i kuhikuhi ʻia, chemotherapy, a me nā steroids) he mea kūpono loa ia i ka luku ʻana i nā hunaola kanesa. Ma muli o kāu hōʻailona, hāʻawi kēia lāʻau i kahi manawa kūpono e hiki ai i ke kala piha.
Leka Lawe-Home
- He hui kūpono loa ʻo R-CHOP o 5 mau lāʻau lapaʻau i hoʻohana ʻia e mālama i nā maʻi ʻaʻai e like me ka non-Hodgkin lymphoma.
- Hoʻokele ʻia ka lāʻau lapaʻau ma nā "pōʻaiapuni." I loko o kēia manawa, manaʻo ʻia ka luhi, ka nausea, a me ka pohō lauoho i nā hopena ʻaoʻao.
- Hiki ke mālama ʻia ka hapa nui o nā hopena ʻaoʻao. E kamaʻilio ākea a pinepine me kāu hui lapaʻau Nirogi Lanka.
- Inā loaʻa iā ʻoe ke kuni i ka wā o ka mālama ʻana, e mālama iā ia ma ke ʻano he pilikia olakino a e ʻimi koke i ka mālama.
- ʻAʻole pono ʻoe e hele hoʻokahi ma kēia ala. E hilinaʻi i kou ʻohana, nā hoaaloha, a me kāu hui lapaʻau. He ikaika ʻoe, a hiki iā ʻoe ke lanakila ma luna o kēia.
R-CHOP, Kanesa, Non-Hodgkin lymphoma, chemotherapy, lāʻau lapaʻau i kuhikuhi ʻia, mālama ʻana i ka maʻi kanesa, nā hopena ʻaoʻao
