Loaʻa iā ʻoe ka maʻi diabetes Type 2? A i ʻole he maʻi puʻuwai a i ʻole ke koko? Inā pēlā, ua kuhikuhi paha kāu kauka iā ʻoe i kahi lāʻau lapaʻau i kapa ʻia ʻo Empagliflozin, i ʻike ʻia hoʻi ʻo Jardiance. Hāʻawi ʻia kēia lāʻau lapaʻau i ka poʻe ʻaʻohe maʻi diabetes akā he mau maʻi puʻuwai hāʻule. No laila, ʻoiai he lāʻau lapaʻau kēia e kuhikuhi ʻia nei i nā poʻe he nui i kēia manawa, e kamaʻilio kākou e pili ana i ia mea me nā kikoʻī hou aku i kēia lā, me he mea lā e kamaʻilio ana kākou me kahi hoaaloha.
Pehea ka hana a kēia lāʻau lapaʻau ʻo Empagliflozin (Jardiance)?
He ʻano ʻepekema iki paha kēia, akā he maʻalahi loa ia. No loko kēia lāʻau lapaʻau i kahi papa o nā lāʻau i kapa ʻia ʻo SGLT2 inhibitors. ʻO ka inoa piha ʻo Sodium-glucose co-transporter 2 inhibitor.
ʻAe, i kēia manawa ma nā ʻōlelo maʻalahi, eia ka mea e hana nei:
Loaʻa i ko kākou mau puʻupaʻa kahi protein i kapa ʻia ʻo SGLT2. ʻO kāna hana ke komo hou i ke kō (glucose) mai ke koko a hoʻi i loko o ke kino. Hoʻopaʻa ʻo Empagliflozin i kēia protein i kapa ʻia ʻo SGLT2. A laila , ʻaʻole e komo hou nā puʻupaʻa i ke kō keu i loko o ke koko a hoʻi i loko o ke kino, akā, e hoʻopuka aku i loko o ka mimi. Ua like ia me kahi kānana e wehe ana i nā mea makemake ʻole ʻia. Ma kēia ʻano, ua kāohi ʻia ka nui o ke kō i loko o ke kino.
Hoʻemi pū kēia lāʻau lapaʻau i ka reabsorption o ka sodium (paʻakai) mai nā puʻupaʻa i loko o ke kino. Hoʻemi kēia i ka ukana hana ma ka puʻuwai. ʻO ia ke kumu he mea pono loa kēia lāʻau lapaʻau no ka poʻe me ka maʻi puʻuwai.
He aha kāu e manaʻo ai i ka wā e hoʻohana ai i kēia lāʻau lapaʻau?
He pila ʻo Empagliflozin āu e lawe ai i hoʻokahi manawa i ka lā. ʻOi aku ka maikaʻi o ka hoʻomau ʻana i ka manawa like i kēlā me kēia lā. ʻŌlelo pinepine nā kauka iā ʻoe e lawe i ke kakahiaka. Hiki iā ʻoe ke lawe me ka meaʻai a me ka ʻole.
Loaʻa kēia lāʻau lapaʻau i ʻelua mau ikaika: 10 milligrams (10 mg) a me 25 milligrams (25 mg). Hiki i kāu kauka ke hoʻomaka iā ʻoe me kahi mahele haʻahaʻa a laila hoʻonui i ka mahele inā pono.
He aha kāu e hana ai inā poina iā ʻoe? Inā poina iā ʻoe ke lawe i kahi pila, e lawe koke i ka wā e hoʻomanaʻo ai ʻoe. Akā inā kokoke ka manawa no kāu pila aʻe, mai lawe i ka pila i poina a me ka pila aʻe i ka manawa like. E kāpae i ka pila i poina a lawe i ka pila aʻe i ka manawa i hoʻonohonoho ʻia.
I kekahi manawa e hāʻawi kāu kauka iā ʻoe i kēia lāʻau lapaʻau me ka hui pū ʻana me kekahi lāʻau lapaʻau maʻi diabetes. No ka laʻana, hiki iā ʻoe ke loaʻa iā ia me ka hui pū ʻana me ka metformin (i kapa ʻia ʻo Synjardy) a i ʻole me ka linagliptin (i kapa ʻia ʻo Glyxambi) ma ke ʻano he pila hoʻokahi.
I mea e loaʻa ai ka hopena maikaʻi loa mai kēia lāʻau lapaʻau, he mea nui e ʻai i ka meaʻai olakino a hoʻoikaika kino mau , e like me ka ʻōlelo a kāu kauka. A mai poina e inu i ka wai nui i ka lā a pau.
ʻOiai ʻoe e lawe ana i kēia lāʻau lapaʻau, e hana pinepine kāu kauka i nā hoʻokolohua koko e nānā i ka hana maikaʻi o kou mau puʻupaʻa. E haʻi aku nō hoʻi ʻo ia iā ʻoe e nānā mau i kou pae kō koko. Hiki ke hala a hiki i 6 mau mahina no ka ʻike piha ʻana i ka hopena o kēia lāʻau lapaʻau.
He aha nā hopena ʻaoʻao o kēia?
E like me nā lāʻau lapaʻau āpau, hiki i kēia ke loaʻa nā hopena ʻaoʻao liʻiliʻi. Akā, mai hopohopo, ʻaʻole koʻikoʻi ka hapa nui o lākou. E nānā kākou i kēia mau hopena ʻaoʻao.
| Ka hopena ʻaoʻao | Ka wehewehe a me nā mea e hana ai |
|---|---|
| Nā hopena ʻaoʻao maʻamau | |
| Nā maʻi hū ma ka ʻāpana genital | ʻOi aku ka maʻamau i nā wahine, akā hiki ke loaʻa i nā kāne. ʻO nā hōʻailona e komo pū me ka maneʻo, ka ʻeha, ka pehu ʻana, ka ʻulaʻula, a me ka kahe ʻana o ke koko. Aia nā lāʻau lapaʻau no kēia mau mea, no laila e ʻike i ke kauka inā loaʻa iā ʻoe kēia mau hōʻailona. |
| Nā maʻi ʻōpū mimi (UTI) | Hiki ke loaʻa nā hōʻailona e like me ke kuni, ka ʻeha, ka mimi pinepine, ka mimi ʻeleʻele, a i ʻole ke koko. Hiki nō hoʻi ke loaʻa ka ʻeha o ka ʻōpū. E haʻi i kāu kauka e pili ana i kēia mau mea no ka mea pono lākou i ka mālama ʻana. |
| Nā hopena ʻaoʻao liʻiliʻi ʻē aʻe | Hiki paha iā ʻoe ke ʻike i nā mea e like me ka makewai nui, ka mimi pinepine ʻana, ka nausea, ka ʻeha o nā hono, a me nā maʻi ʻāʻī. Nalowale pinepine kēia mau mea i ka hala ʻana o ka manawa ke hoʻomaʻamaʻa kou kino i ka lāʻau lapaʻau. Inā hoʻomau lākou, e haʻi i kāu kauka. |
| Nā hopena ʻaoʻao koʻikoʻi e pono ai ka nānā koke ʻana | |
| Nā maʻi ʻōpū mimi koʻikoʻi | Kuni, anuanu, ʻeha nui ma ka ʻōpū lalo a i ʻole ke kua. He mau hōʻailona paha kēia o kahi maʻi e hoʻopilikia ana i nā puʻupaʻa. E ʻimi koke i ke kōkua lapaʻau. |
| Ke koko haʻahaʻa | ʻO ka poʻo hina, ka māmā o ke poʻo, ʻoiai i ka wā e kū ana. |
| Haʻahaʻa ke kō koko | Hiki ke ʻike ʻia nā hōʻailona e like me ka hou ʻana, ka haʻalulu, ka piʻi ʻana o ka puʻuwai, ka pōloli, a me ka huikau, ʻoiai ke lawe ʻia me nā lāʻau lapaʻau maʻi diabetes ʻē aʻe. |
| ʻO ka gangrene o Fournier | He maʻi koʻikoʻi loa kēia o ka ʻāpana genital. ʻO nā hōʻailona e komo pū me ka ʻeha nui ma ia wahi, ka pehu ʻana, ke kuni, a me ka luhi nui. He pilikia kēia, e hele koke i ka Emergency Department (ETU) o ka haukapila. |
| Ketoacidosis maʻi diabetes | He maʻi koʻikoʻi loa ia i hoʻokumu ʻia e ke kō koko kiʻekiʻe. ʻO nā hōʻailona e komo pū me ka makewai nui, ka mimi pinepine, ka ʻeha o ka ʻōpū, ka nausea, ka nāwaliwali, a me kahi ʻala hua ma ka hanu. He pilikia nō hoʻi kēia, e hele koke i ka ETU. |
| Nā hopena maʻi ʻaleka | ʻŌhūhū ʻili, pehu ʻana o ka maka, nā lehelehe, a i ʻole ka ʻāʻī, paʻakikī ke ale a hanu paha. He pilikia nō hoʻi kēia, e ʻimi koke i ke kōkua lapaʻau. |
Nā ʻōlelo aʻo a me nā hana palekana e pono e hoʻomaopopo ʻia ma mua o ka hoʻohana ʻana
Ma mua o ka hoʻomaka ʻana i kēia lāʻau lapaʻau, he mea nui loa ia e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei (me nā lāʻau lapaʻau no nā kūlana ʻē aʻe, nā huaora, nā mea hoʻohui, a me nā lāʻau lapaʻau kuʻuna). Hiki i ka Empagliflozin ke launa pū me nā lāʻau lapaʻau ma lalo nei:
- Nā lāʻau lapaʻau maʻi diabetes ʻē aʻe
- Nā lāʻau lapaʻau koko e like me nā mea hoʻopaʻa ACE a me nā mea pale Angiotensin receptor (ARBs)
- ʻO nā diuretics a i ʻole "nā pila wai"
- Nā lāʻau hoʻopau ʻeha e like me ka aspirin, ibuprofen, a me ka naproxen
Pono paha kāu kauka e hoʻololi i ka nui o nā lāʻau lapaʻau ʻē aʻe āu e lawe nei a i ʻole e makaʻala hou aku i nā hopena ʻaoʻao.
Inā loaʻa iā ʻoe nā hōʻailona o ka ketoacidosis, hiki i kāu kauka ke noi iā ʻoe e nānā i kou koko no nā ketones. Aia nā mea hana kūikawā a i ʻole nā ʻāpana hoʻāʻo mimi no kēia.
Mai poina e inu i ka wai nui , no ka mea, hiki i kēia lāʻau lapaʻau ke hoʻomaloʻo i ka wai.
E haʻi i kāu kauka inā inu ʻoe i ka waiʻona, a inā he mau maʻi hū pinepine kāu a i ʻole nā maʻi ʻōpū urinary.
ʻO wai ka mea pono ʻole e lawe i kēia lāʻau lapaʻau?
ʻAʻole kūpono ʻo Empagliflozin no nā kānaka a pau. Aia kekahi mau kūlana kahi e pono ʻole ai e lawe ʻia kēia lāʻau lapaʻau:
- Inā ʻoe e hana ʻia ana i ka dialysis kidney.
- Inā he makuahine hānai ʻoe (hiki i ka lāʻau lapaʻau ke hele i ka pēpē ma o ka waiū umauma).
- Inā hāpai ʻoe a i ʻole e hoʻolālā ana e hāpai (no ka mea e hōʻeha paha i ka pēpē, e kamaʻilio me kāu kauka e pili ana i kēia).
- Inā he maʻi ʻoe i ka empagliflozin a i ʻole kekahi o kāna mau mea hoʻohui.
Eia kekahi, ʻaʻole i ʻae ʻia kēia lāʻau lapaʻau no ka poʻe me ka Type 1 Diabetes, no ka mea e hoʻonui paha i ko lākou pilikia o Ketoacidosis.
Pehea ka maikaʻi o ka Empagliflozin (Jardiance)?
Ua hoʻopaʻa maikaʻi ʻia ka pono o kēia lāʻau lapaʻau i nā hoʻokolohua lapaʻau. Ma kahi noiʻi 6 mahina i nā pākeke me ka maʻi diabetes type 2, ʻo Empagliflozin:
- Ua emi maʻamau ka nui o ke kō koko hoʻokē ʻai ma kahi o 19-25.
- Ua emi iho ka waiwai A1c, ka mea e hōʻike ana i ka awelika o ke kō koko i nā mahina 2-3 i hala, ma 0.7% - 0.8%.
Eia kekahi, ua emi ke kaumaha o kekahi poʻe. ʻO ka poʻe i lawe i ka mahele 10mg i kēlā me kēia lā ua emi ma kahi o 2.5% o ko lākou kaumaha kino (no ka laʻana, ma kahi o 2.25 kg no ke kanaka 90 kg). ʻO ka poʻe i lawe i ka mahele 25mg ua emi ma kahi o 2.8% o ko lākou kaumaha kino (no ka laʻana, ma kahi o 2.5 kg no ke kanaka 90 kg).
Ua emi iki hoʻi ke kaomi koko systolic i ka poʻe i lawe i kēia lāʻau lapaʻau.
Leka Lawe-Home
- He lāʻau lapaʻau ʻo Empagliflozin (Jardiance) i hoʻohana ʻia no ka mālama ʻana i ka maʻi diabetes a me kekahi mau maʻi puʻuwai. Hana ia ma ke kōkua ʻana i nā puʻupaʻa e hoʻoneʻe i ke kō keu mai ke kino ma o ka mimi.
- E lawe i kēia lāʻau lapaʻau e like me ke kauoha a kāu kauka, i ka manawa like i kēlā me kēia lā. Inā ʻoe e poina i kahi mahele lāʻau, mai lawe i ʻelua mau mahele lāʻau i ka manawa like i ka manawa aʻe.
- He mea maʻamau nā maʻi ʻōpū mimi a me nā maʻi hū genital me kēia lāʻau lapaʻau. E haʻi i kāu kauka inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona.
- E inu i ka wai he nui i ka lā a pau no ka mea hiki i kēia lāʻau lapaʻau ke hoʻomaloʻo i ka wai.
- He mea nui e hoʻomaopopo i kāu kauka e pili ana i nā lāʻau lapaʻau ʻē aʻe āu e lawe nei.
- Inā loaʻa iā ʻoe nā hōʻailona koʻikoʻi e like me nā hopena alerika koʻikoʻi, ka paʻakikī o ka hanu ʻana, ka gangrene ʻo Fournier, a i ʻole ketoacidosis , e hele koke i ka keʻena pilikia o ka haukapila (ETU).
- Mai ho'ōki i ka lawe ʻana i kēia lāʻau me ke aʻo ʻole ʻia e ke kauka.
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