E ʻōlelo kākou ua hele ʻoe e ʻike i ke kauka no kahi nānā maʻamau a loaʻa iā ʻoe nā hopena o kāu hoʻāʻo koko. ʻŌlelo ke kauka, nāna i nānā i ka hōʻike, "Ua kiʻekiʻe iki kou mau enzymes akepaʻa." ʻIke ʻoe ua ʻoi aku ke kiʻekiʻe o nā waiwai ma mua o nā leka ʻelua ALT a me AST i kāu hōʻike ma mua o ka maʻamau. He mea maʻamau ke manaʻo iki i ka makaʻu i ka wā e hana ʻia ai kēia. Akā, mai hopohopo. I kēia lā, ke kamaʻilio nei mākou e pili ana i kahi maʻi i kapa ʻia ʻo "Transaminitis", kahi i hoʻokiʻekiʻe ʻia ai nā enzymes akepaʻa.
I ka ʻōlelo maʻalahi, he aha ka Transaminitis?
ʻAʻole he maʻi koʻikoʻi ka 'Transaminitis'. ʻO ia hoʻi, ua piʻi nui ka pae o kekahi mau enzymes i kapa ʻia ʻo 'transaminases' i loko o kou koko. ʻO nā enzymes nui ʻelua ʻo 'Alanine Transaminase (ALT)' a me 'Aspartate Transaminase (AST)' .
E noʻonoʻo i kou akepaʻa e like me kahi hale hana nui. ʻO kēia mau enzymes nā limahana i loko o nā cell o kēlā hale hana. ʻO ka maʻamau, aia kēia mau limahana i loko o ka hale hana. Akā i ka wā e pilikia ai ke akepaʻa, hōʻino ʻia, a i ʻole ke kaumaha, ua hōʻino ʻia nā cell ate a ua kahe kekahi o kēia mau limahana i waho, ʻo ia hoʻi, i loko o ko kākou koko. Me kahi hōʻike hoʻāʻo koko, ana mākou i ka nui o nā enzymes i hōʻiliʻili ʻia i loko o ke koko.
ʻO ka hapa nui o ka manawa, ʻike ʻia kēia ʻano ma ka manawa kūpono. Loaʻa nā pae ALT a me AST kiʻekiʻe i ka wā o kahi hoʻāʻo koko i hana ʻia no kekahi kumu ʻē aʻe. Eia nō naʻe, no kekahi poʻe, ke loaʻa iā lākou nā hōʻailona e like me ka jaundice, ka melemele o nā maka a me ka ʻili, a i ʻole ka ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū, kauoha ke kauka i kēia mau hoʻokolohua, ʻoiai e nānā i ka hana o ke akepaʻa.
He mea weliweli anei ke kiʻekiʻe o kēia mau enzymes?
He pilikia kēia i loaʻa i nā kānaka he nui. ʻO ka 'Transaminitis' ka ʻōlelo aʻo mua e hōʻike ana ua hōʻino ʻia nā hunaola akepaʻa. Ua like ia me ke kukui 'check engine' ma ke kaʻa e ʻā ana. Hōʻike ia iā ʻoe aia kekahi mea hewa me ke kaʻa, a pono ʻoe e nānā iā ia. A pēlā nō hoʻi kēia.
ʻO ke koʻikoʻi o kēia ma muli o ke kumu kumu .
- Nā kumu no ka manawa pōkole: Hiki ke hoʻokiʻekiʻe ʻia kēia mau enzymes no ka manawa pōkole i ka wā e lawe ai i kekahi mau lāʻau lapaʻau a i ʻole ma muli o kahi maʻi no ka manawa pōkole. Ke pau ke kumu, hoʻōla ke akepaʻa a hoʻi nā pae enzyme i ka maʻamau.
- Nā kumu lōʻihi: Eia nō naʻe, inā hoʻomau kēia pōʻino ma muli o kahi maʻi mau, hiki ke lilo i mea koʻikoʻi i ka hala ʻana o ka manawa. Loaʻa i ko kākou akepaʻa kahi hiki kupaianaha ke ho'ōla, akā i ka wā e hoʻomau ai ka pōʻino, nalowale kēlā hiki a hiki ke alakaʻi i kahi kūlana i kapa ʻia ʻo ka hāʻule ʻana o ke akepaʻa.
No laila, ʻaʻole kēia he helu hoʻokahi wale nō. He hōʻailona koʻikoʻi ia e hāʻawi iā ʻoe i kahi manaʻo o kou olakino holoʻokoʻa.
He aha nā kumu e hiki ai ke hoʻoulu i ka transaminitis?
Nui nā kumu no kēia. E hoʻokaʻawale kākou iā lākou i ʻelua mau ʻāpana: nā kumu maʻamau a me nā kumu i emi iki ka maʻamau.
| Kumu | He wehewehe maʻalahi |
|---|---|
| Nā Kumu Maʻamau | |
| Maʻi ʻAke Momona | I kēia manawa, he kumu maʻamau loa ia ma Sri Lanka. ʻO ke ʻano kikoʻī, he maʻi i kapa ʻia ʻo Metabolic dysfunction-associated steatotic liver disease (MASLD) . ʻO nā mea metabolic e like me ka ʻai maikaʻi ʻole, ka piʻi ʻana o ke kaumaha, ka maʻi diabetes, a me ke cholesterol kiʻekiʻe e kōkua i kēia. |
| Ka hoʻohana nui ʻana i ka waiʻona (Hepatitis i hoʻoulu ʻia e ka waiʻona) | ʻO ka inu nui ʻana i ka waiʻona e hōʻino pololei i ke akepaʻa, hiki ke alakaʻi i ka hōʻino ʻana i ke akepaʻa no ka manawa pōkole a i ʻole ka wā lōʻihi. |
| Nā maʻi viral (Viral Hepatitis) | Hiki i nā maʻi e like me ka hepatitis A, B, C, D, a me E ke kumu o ka mumū o ke ake. Hiki i kēia ke alakaʻi i ka hepatitis B a me C mau loa. |
| Nā hopena i hoʻoulu ʻia e ka lāʻau lapaʻau (Hepatitis ʻawahia) | Hiki i kekahi mau lāʻau ʻeha, nā lāʻau hoʻohaʻahaʻa cholesterol, nā lāʻau maʻi puʻupuʻu, a me nā lāʻau ʻē aʻe ke hoʻopilikia i ke akepaʻa. Ke makaʻala mau nei ke kauka i kēia. |
| Nā Kumu Maʻamau ʻole | |
| Nā kumu ʻē aʻe | Nā kūlana e like me nā pilikia o ka ʻōnaehana pale (autoimmune hepatitis), nā maʻi hoʻoilina (hemochromatosis, maʻi Wilson), hōʻeha puʻuwai, jaundice, maʻi thyroid, a me ka maʻi kanesa ate. |
He manaʻo kūikawā anei inā ʻoi aku ke kiʻekiʻe o AST ma mua o ALT?
ʻO ka maʻamau, ke hōʻino ʻia ke akepaʻa, hoʻonui pū ʻia kēia mau enzyme ʻelua. ʻOi aku ka kikoʻī o ka enzyme ALT i ke akepaʻa. ʻO ia hoʻi, loaʻa nui ia i loko o ke akepaʻa. Eia nō naʻe, loaʻa pū ka enzyme AST i loko o ka ʻiʻo puʻuwai, nā ʻiʻo iwi, a me nā ʻiʻo ʻē aʻe ma waho aʻe o ke akepaʻa.
No laila, inā ʻoi aku ka nui o ka waiwai AST ma mua o ka waiwai ALT , e noʻonoʻo pū ke kauka i nā kumu ʻē aʻe. Eia kekahi laʻana:
- Maʻi akepaʻa i hoʻoulu ʻia e ka waiʻona: I kēia kūlana, piʻi ka lakio AST/ALT.
- ʻO Cirrhosis: Hiki ke ʻike ʻia kēia ʻano i ka wā e holomua ana ka maʻi.
- Nā kumu extrahepatic: Hiki ke hoʻokiʻekiʻe ʻia nā pae AST i nā hihia e like me ka myocardial ischemia a i ʻole ka hōʻino nui ʻana o nā ʻiʻo (rhabdomyolysis).
ʻO ka mea nui loa: He mau ʻōlelo aʻoaʻo wale nō kēia. Mai hoʻāʻo e nānā iā ʻoe iho ma muli o kāu hōʻike. Pono e hana ʻia kēlā e kāu kauka.
Pehea lā e mālama ai ke kauka i kēia?
ʻO ka mea mua, e hoʻomanaʻo ʻaʻohe lāʻau lapaʻau pololei no ka 'Transaminitis'. No ka mea, ʻaʻole ia he maʻi, akā he hōʻailona. No laila, ʻo ka pahuhopu nui o ke kauka ke ʻimi i ke kumu o nā enzymes kiʻekiʻe a mālama i kēlā kumu.
ʻO ke kaʻina hana lapaʻau e like me kēia:
1. Mōʻaukala lapaʻau: E nīnau ke kauka iā ʻoe e pili ana i kou nohona (ʻai, hoʻoikaika kino, hoʻohana ʻana i ka waiʻona), nā lāʻau lapaʻau āu e lawe ai, a me nā kūlana olakino i loko o kou ʻohana.
2. Nā hoʻokolohua hou aʻe: E kauoha ʻia nā hoʻokolohua hou aʻe e hōʻoia i ke kumu.
- E hana hou i ka hoʻāʻo koko.
- Nā hoʻāʻo no ka maʻi hepatitis B a me C.
- ʻO ke kiʻi ʻana o ka ultrasound ʻōpū.
- Inā pono, nā hoʻāʻo koko kūikawā ʻē aʻe.
3. Lāʻau lapaʻau e like me ke kumu: Hoʻoholo ʻia ka lāʻau lapaʻau ma hope o ka loaʻa ʻana o ke kumu.
- ʻAke Momona: He mea nui nā hoʻololi ʻana i ke ʻano o ka nohona. He mea nui ka ʻai olakino , ka hoʻoikaika kino mau , a me ka pohō kaumaha .
- Inā ma muli o ka waiʻona: ʻO ka hopena wale nō, ʻo ia ke hoʻōki loa i ka hoʻohana ʻana i ka waiʻona .
- Inā ma muli o ka lāʻau lapaʻau: Na ke kauka e hoʻoholo inā e hoʻololi i ka lāʻau lapaʻau a hōʻemi paha i ka nui.
- Inā ma muli o kahi huakino: E hoʻomaka ka lāʻau no kēlā huakino.
I ka hapanui o nā hihia, ke mālama pono ʻia ke kumu kumu, e pau ka hōʻino ʻana i ke akepaʻa a hoʻi hou nā pae enzyme i ka maʻamau.
Leka Lawe-Home
- ʻO ka Transaminitis (nā enzymes akepaʻa kiʻekiʻe) he hōʻailona ia e hōʻike ana ua pilikia kou akepaʻa. Mai hopohopo ke ʻike ʻoe.
- Nui nā kumu no kēia. ʻO ke akepaʻa momona, ka hoʻohana ʻana i ka waiʻona, nā maʻi viral, a me kekahi mau lāʻau lapaʻau nā kumu maʻamau.
- ʻAʻole kuhikuhi ʻia ka lāʻau lapaʻau i ka pae enzyme, akā i ke kūlana kumu i hoʻoulu ai i kona piʻi ʻana.
- Inā ʻike ʻoe i nā pae ALT a me AST kiʻekiʻe i kāu hoʻāʻo koko, mai hoʻowahāwahā iā ia. E hōʻoia e ʻike i kāu kauka no ka ʻōlelo aʻo kūpono a me ka lāʻau lapaʻau.
- I nā manawa he nui, ʻo ka lawe ʻana i kahi nohona olakino (ʻai maikaʻi, hoʻoikaika kino) he mea kōkua nui ia i ka mālama ʻana i ke olakino o ke akepaʻa.
👩🏽⚕️ Nā nīnau hou aku (FAQs)
💬 He aha ka Syncope / Fainting?
ʻAʻole kēia he manawa hiamoe/luhi wale nō! ʻO ka 'Syncope' i ka lāʻau lapaʻau he pilikia olakino weliweli loa ia, ma muli o kekahi kumu make a koke paha, ua pau loa ke koko a me ka oxygen i ka lolo no kekahi mau kekona (Portatory lost of blood flow to the brain), e hiolo koke ai ke kanaka i ka honua (Loss of consciousness/Postural tone collapse) a nalowale ka ʻike!
💬 He aha nā kumu nui o ka syncope/hiolo ʻana i ka wā e kū/hele ana ke kanaka?
ʻEhā mau kumu nui o kēia: 1) 'Cardiogenic Syncope' - Inā pau koke ka puʻuwai i ke kuʻi ʻana/loaʻa i ka hōʻeha puʻuwai, ʻaʻole hiki i ka puʻuwai ke pamu i ke koko i ka lolo, e lilo ai ka ʻike! 2) Hypoglycemia (i nā maʻi diabetes). 3) Vasovagal syncope - Nalowale ka ʻike ma muli o ke kūpikipikiʻi o ke aʻalolo i ka ʻeha hiki ʻole ke hoʻomanawanui/i ka ʻike ʻana i ke koko/makaʻu nui. 4) Nā hopu/Epilepsy.
💬 Ke hāʻule kekahi, he aha nā 'kūlana make/pilikia' e pono ai ka lawe koke ʻia ʻana i ka haukapila, ma mua o ka ninini wale ʻana i ka wai ma ko lākou alo a noho ma ka home?
Inā hāʻule ʻoe a ala aʻe i loko o kekahi mau kekona/inā hāʻule ʻoe ma hope o ka moe ʻana, e hoʻāʻo e hāʻawi i kahi wai/kō. Akā ʻo ka pōʻino nui loa! Ma mua o kou nalowale ʻana o ka ʻike a hāʻule, inā 1) loaʻa iā ʻoe ka ʻeha umauma/hōʻeha puʻuwai a paʻakikī paha ka hanu ʻana, 2) ke hāʻule ʻoe, haʻalulu kou kino holoʻokoʻa a ʻūlū/huʻa ma ka waha (seizures/fits), 3) inā hāʻule ʻoe a ʻaʻole ʻōlelo i kahi huaʻōlelo/aia i loko o ka coma no kekahi mau minuke, pono ʻoe e kāhea koke i kahi ambulance a lawe iā lākou i ka haukapila!
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