Aldosterone yog dab tsi? Cia peb kawm seb nws cuam tshuam li cas rau koj cov ntshav siab!

Koj puas tau hnov ​​txog Aldosterone? Tej zaum koj tus kws kho mob tau hais txog nws, lossis tej zaum koj tau hnov ​​lub npe thaum tham txog koj cov ntshav siab. Nws yog ib qho tshuaj hormones me me tab sis tseem ceeb heev hauv peb lub cev. Nws pab tswj cov sodium thiab potassium hauv peb lub cev thiab ua kom peb cov ntshav siab nyob hauv kev tswj. Yog li, cia peb tham txog Aldosterone hnub no hauv txoj kev yooj yim uas koj tuaj yeem nkag siab, puas yog?

Aldosterone yog dab tsi? Nws los qhov twg los?

Hais yooj yim xwb, Aldosterone yog ib yam tshuaj hormones uas koj cov qog adrenal tsim tawm. Koj puas paub cov qog adrenal no yog dab tsi? Lawv yog ob lub qog me me, zoo li peb ceg uas zoo li lub kaus mom me me saum koj lub raum. Lawv yog ib feem ntawm peb lub cev endocrine . Cov qog no tsim ntau yam tshuaj hormones uas tseem ceeb rau peb lub cev.

Cov tshuaj hormones zoo li cov tshuaj xa xov uas sib koom tes ua haujlwm ntawm peb lub cev. Lawv mus ncig thoob plaws hauv cov ntshav thiab qhia rau cov kabmob, cov leeg, thiab lwm cov nqaij txog yam yuav tsum ua thiab thaum twg yuav tsum ua.

Tam sim no, cov tshuaj hormones no, Aldosterone, tswj cov sodium thiab potassium hauv koj cov ntshav. Cov sodium thiab potassium no hu ua electrolytes . Cov no yog cov uas pab kom cov kua dej hauv lub cev sib npaug thiab pab cov hlab ntsha thiab cov leeg ua haujlwm kom zoo. Tsis tas li ntawd, Aldosterone tswj cov dej uas lub raum nqus rov qab. Qhov no ua rau cov ntshav ntim ntau ntxiv thiab cuam tshuam rau cov ntshav siab.

Yog li, txawm tias koj cov aldosterone qis lossis siab, nws tuaj yeem cuam tshuam rau koj txoj kev noj qab haus huv.

Aldosterone muab kev pabcuam dab tsi rau peb lub cev?

Lub luag haujlwm tseem ceeb ntawm Aldosterone yog los pab tswj koj cov ntshav siab. Nws pab txhawb rau txoj haujlwm tseem ceeb no hauv ntau txoj kev:

• Aldosterone ua rau cov kabmob xws li koj lub raum thiab txoj hnyuv loj kom ntxiv cov sodium rau hauv koj cov ntshav lossis kom ntxiv cov potassium uas tawm hauv koj cov zis.
• Thaum cov sodium nce ntxiv li no, lub cev pib khaws dej, uas ua rau cov ntshav ntim ntau ntxiv.

Tag nrho cov no yog qhov tseem ceeb, thaum cov ntshav siab qis, kom coj nws rov qab mus rau qib noj qab haus huv.

Tsis ncaj qha, aldosterone kuj pab tswj lub pH (piv txwv li, acid-base sib npaug) thiab cov electrolyte ntawm koj cov ntshav.

Cov theem aldosterone raug tswj li cas? Cia peb saib ze dua!

Aldosterone yog ib feem ntawm ib lub network ntawm cov tshuaj hormones, enzymes, proteins, thiab cov tshuaj tiv thaiv hu ua Renin-Angiotensin-Aldosterone System (RAAS) . Nws yog lub luag haujlwm tseem ceeb rau kev tswj cov ntshav siab.

Xav txog qhov no ua ib kauj ruam zuj zus:

1. Ua ntej, thaum koj cov ntshav siab poob qis , ib qho enzyme hu ua renin raug tso tawm rau hauv koj cov ntshav los ntawm koj lub raum.

2. Cov renin no mus thiab rhuav tshem cov protein hu ua angiotensinogen , uas yog tsim nyob rau hauv koj lub siab. Ib qho ntawm cov khoom yog angiotensin I. Qhov no tsis ua haujlwm rau lub sijhawm ntawd, uas txhais tau tias nws tsis muaj ntau yam cuam tshuam.

3. Tom qab ntawd, Angiotensin-Converting Enzyme (ACE) los ntawm koj lub ntsws tuaj txog thiab rhuav Angiotensin I no ua ntau daim. Ib qho ntawm cov daim ntawd yog cov tshuaj hormones hu ua Angiotensin II .

4. Qhov no yog qhov uas Angiotensin II ua haujlwm tseem ceeb:

• Ib qho yog ua kom cov ntshav siab ntxiv los ntawm kev ua rau cov leeg ntawm cov hlab ntsha me me (arterioles) qaug zog.
• Qhov thib ob yog tias nws "qhia" koj cov qog adrenal kom tso aldosterone.
• Nws kuj qhia koj lub qog pituitary kom tso tawm Antidiuretic Hormone (ADH) , tseem hu ua Vasopressin .

5. Yog li, Aldosterone thiab ADH ua haujlwm ua ke los qhia rau lub raum kom khaws sodium hauv lub cev. Aldosterone ua rau lub raum tso potassium tawm hauv cov zis. Thaum cov sodium hauv cov ntshav nce ntxiv, dej yuav khaws cia rau hauv lub cev. Qhov no ua rau cov ntshav ntim thiab ntshav siab ntxiv.

Nov yog li cas Renin-Angiotensin-Aldosterone System thiaj ua tiav. Koj puas nkag siab txog cov txheej txheem ntawd?

Lub cev no kuj tseem tuaj yeem ua haujlwm los ntawm lwm cov tshuaj hormones xws li corticosteroids , estrogen, thiab thyroid hormones .

Yog tias muaj teeb meem nrog ib feem ntawm lub cev no, nws tuaj yeem cuam tshuam rau koj cov ntshav siab thiab sodium thiab potassium. Txawm li cas los xij, nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias muaj ntau yam ntxiv uas tuaj yeem cuam tshuam rau koj cov ntshav siab, xws li cov roj cholesterol ntau, cov noob caj noob ces, thiab qee yam tshuaj.

Yuav ua li cas los xyuas cov theem ntawm aldosterone?

Qhov kev kuaj tseem ceeb uas cov kws kho mob siv los kuaj xyuas cov teeb meem ntsig txog aldosterone yog Aldosterone: Renin Ratio Test . Vim tias renin thiab aldosterone muaj feem cuam tshuam ze, qhov kev kuaj no tuaj yeem txiav txim siab seb qhov teeb meem tsuas yog teeb meem nrog kev tsim thiab kev ua haujlwm ntawm aldosterone, lossis seb puas muaj teeb meem nrog lub cev renin-angiotensin nws tus kheej.

Rau qhov kev xeem Aldosterone: Renin Ratio no, feem ntau yuav muab cov ntshav los ntawm cov leeg ntshav hauv koj txhais caj npab.

Cov kws kho mob kuj tseem tuaj yeem ntsuas qhov ntau ntawm aldosterone hauv koj cov ntshav thiab / lossis zis.

Qee zaum, koj tus kws kho mob yuav hais kom koj muab ib qho kev kuaj ntshav los ntawm cov hlab ntsha hauv koj lub raum (rau renin) lossis cov hlab ntsha hauv koj lub qog adrenal (rau aldosterone). Qhov no yog ib qho kev kuaj uas ua hauv tsev kho mob los ntawm ib tug kws kho mob uas tau kawm tshwj xeeb hauv kev kuaj mob.

Cov theem ib txwm ntawm aldosterone yog dab tsi?

Cov nqi ib txwm rau cov theem aldosterone tuaj yeem sib txawv me ntsis ntawm ib lub chaw kuaj mob mus rau lwm qhov. Yog li, nco ntsoov xyuas qhov ntau thiab tsawg ib txwm muaj ntawm koj daim ntawv qhia chaw kuaj mob, lossis nug koj tus kws kho mob yog tias koj muaj lus nug txog koj cov txiaj ntsig.

Cov theem ib txwm muaj ntawm aldosterone hauv cov ntshav sib txawv raws li hnub nyoog. Feem ntau, cov theem ib txwm muaj raws li nram no:

• Rau cov menyuam mos hnub nyoog 1 txog 12 lub hlis: 5.8 – 110.0 nanograms ib deciliter (ng/dL)
• Rau cov menyuam yaus hnub nyoog 1 txog 5 xyoos: < 36.0 ng/dL
• Rau cov menyuam yaus hnub nyoog 6 txog 9 xyoos: < 24.0 ng/dL
• Rau cov menyuam yaus hnub nyoog 10 txog 11 xyoos: < 15.0 ng/dL
• Rau cov menyuam yaus hnub nyoog 12 txog 14 xyoos: < 22.0 ng/dL
• Rau cov tub ntxhais hluas hnub nyoog 15 txog 17 xyoo: 3.0 – 32.0 ng/dL
• Cov neeg laus hnub nyoog 18 txog 99 xyoo: 3.1 - 35.4 ng/dL

Thaum saib cov theem aldosterone hauv kev kuaj zis 24 teev, qhov ntau thiab tsawg ib txwm yog ntawm 3 - 25 micrograms ib 24 teev (3 - 25 mcg/24 teev).

Yuav ua li cas yog tias cov theem ntawm aldosterone nce siab?

Thaum cov theem aldosterone siab dua li qub, peb hu nws tias hyperaldosteronism .

Qhov ua rau muaj qhov no yog Primary Aldosteronism , tseem hu ua Conn's syndrome . Tus mob no yog tshwm sim los ntawm ib qho qog nqaij hlav uas tsis yog mob qog nqaij hlav (benign) uas feem ntau tshwm sim hauv ib qho ntawm koj cov qog adrenal.Qhov no ua rau lub qog tsim cov aldosterone ntau dua li nws yuav tsum tau. Thaum cov aldosterone nce ntxiv, cov sodium nce ntxiv ( hypernatremia ) thiab cov potassium txo qis ( hypokalemia ). Qhov no tuaj yeem ua rau cov electrolyte tsis sib npaug.

Cov tsos mob ntawm cov aldosterone siab

Yog tias muaj tus kab mob aldosteronism thawj zaug, uas yog, thaum cov qib aldosterone nce siab, cov tsos mob xws li:

• Ntshav siab (Tshuaj ntshav siab)
• Mob taub hau
• Cov leeg tsis muaj zog , tshwj xeeb tshaj yog tias cov potassium qis heev
• Nqhis dej heev thiab tso zis ntau zaus

Yog tias koj muaj cov tsos mob no, nws yog ib qho tseem ceeb heev uas yuav tsum nrhiav kev pab kho mob tam sim ntawd.

Yuav ua li cas yog tias cov theem ntawm aldosterone txo qis?

Thaum cov aldosterone qis dua li qub, peb hu nws tias hypoaldosteronism . Qhov no yog qhov tsis txaus ntawm aldosterone, lossis nws qhov ua haujlwm tsis zoo. Thaum cov aldosterone qis, cov sodium txo qis ( hyponatremia ), cov potassium nce siab ( hyperkalemia ), thiab lub cev tsim cov kua qaub ntau dhau ( metabolic acidosis ).

Muaj ntau yam ua rau hypoaldosteronism:

• Kab mob Addison: Qhov no yog ib qho mob tsis tshua muaj. Nws tseem hu ua Primary Adrenal Insufficiency . Nws yog ib qho kab mob autoimmune . Qhov no txhais tau tias koj lub cev tiv thaiv kab mob tawm tsam sab nraud (cortex) ntawm cov qog adrenal. Ob qho tib si cov tshuaj hormones aldosterone thiab cortisol raug tsim tawm nyob ntawd. Qhov no ua rau cov theem ntawm ob qho tshuaj hormones txo qis.
• Kab mob Adrenal Hyperplasia (CAH): Qhov no yog ib pawg kab mob caj ces uas cuam tshuam rau cov qog adrenal. Cov neeg uas muaj CAH yug los nrog qhov tsis txaus ntawm qee cov enzymes uas xav tau los ua cov tshuaj hormones uas cov qog adrenal tsim tawm.
• Tej yam mob nkeeg: Cov neeg uas muaj mob ntshav qab zib, mob raum, lom los ntawm cov hlau txhuas, lossis mob hnyav tuaj yeem tsim hypoaldosteronism.
• Qee cov tshuaj: Cov tshuaj tsis-steroidal anti-inflammatory (NSAIDs) , HeparinTus mob no kuj tseem tuaj yeem tshwm sim los ntawm cov tshuaj uas tau muab los kho kab mob plawv.

Cov tsos mob ntawm aldosterone qis

Feem ntau, cov aldosterone qis (Hypoaldosteronism) tuaj yeem ua rau muaj cov tsos mob xws li:

• Ntshav siab qis (Hypotension)
• Cov leeg tsis muaj zog
• Xeev siab
• Lub plawv dhia ceev
• Kev tsis sib xws ntawm lub plawv dhia (Arrhythmia)

Nyob ntawm seb koj tus kab mob hypoaldosteronism ua rau koj muaj mob ntxiv li cas. Piv txwv li, hauv tus kab mob Addison, cov cortisol qis tuaj yeem ua rau cov tawv nqaij hloov pauv (xws li cov pob tsaus thiab cov tawv nqaij quav) thiab cov ntshav qab zib qis ( hypoglycemia ).

Yog koj muaj ib qho ntawm cov tsos mob no, mus ntsib koj tus kws kho mob tam sim ntawd.

Thaum kawg, tej yam yuav tsum nco ntsoov (Cov Lus Coj Mus Tsev)

Aldosterone yog ib yam tshuaj hormones uas tseem ceeb rau kev tswj cov ntshav siab. Yog tias koj muaj teeb meem tswj cov ntshav siab kom zoo thiab koj kuj muaj kev hloov pauv hauv koj cov ntshav potassium, nws yog ib lub tswv yim zoo los tham nrog koj tus kws kho mob txog lwm txoj hauv kev tswj cov ntshav siab thiab kev kuaj ntxiv. Tom qab ntawd nws tuaj yeem xaj kev kuaj kom pom tias koj cov tsos mob puas yog vim cov aldosterone tsis zoo.

Vam tias cov ntaub ntawv no yuav pab tau koj! Nyob zoo!

Aldosterone , Aldosterone, Hormone, Ntshav Siab, Cov Qog Adrenal, Sodium, Potassium