Koj cov ntshav puas yooj yim txhaws? Cia peb kawm txog Antithrombin Deficiency!

Txawm tias muaj ib qho qhov txhab me me ntawm peb lub cev, qhov ntshav tsis ntws tom qab ib pliag thiab cov ntshav txhaws, puas yog? Nws yog ib qho txheej txheem zoo kawg nkaus rau peb lub cev los tiv thaiv nws tus kheej. Txawm li cas los xij, yog tias cov ntshav txhaws no nce ntau dua li qhov tsim nyog, lossis yog tias cov ntshav txhaws tsim hauv lub cev tsis muaj laj thawj? Ces nws tuaj yeem yog teeb meem. Hnub no peb yuav tham txog ib qho laj thawj tshwj xeeb uas ua rau cov ntshav txhaws tsis tsim nyog. Ntawd yog Antithrombin Deficiency , qee tus kuj hu nws Antithrombin III Deficiency.

Antithrombin Deficiency yog dab tsi tiag?

Hais yooj yim xwb, qhov tsis muaj antithrombin yog ib qho mob uas cuam tshuam nrog peb cov txheej txheem ntshav txhaws. Hauv qhov no, muaj qhov txo qis ntawm cov protein hu ua antithrombin, ib yam khoom tseem ceeb hauv peb lub cev uas tiv thaiv cov ntshav txhaws ntau dhau, lossis nws tsis ua haujlwm zoo.

Xav txog nws li no. Koj tab tom muab dej ntim rau hauv lub dab da dej. Ib tug neeg yuav tsum tua lub qhov dej ua ntej nws ntws tawm, lossis tag nrho cov dej yuav ntws tawm. Yog li ntawd, thaum peb cov ntshav pib txhaws, nws yog qhov no hu ua antithrombin uas "nres" nws thaum lub sijhawm zoo, tiv thaiv nws kom tsis txhob tshwm sim ntau dhau. Yog li, yog tias koj tsis muaj antithrombin txaus hauv koj lub cev, lossis yog tias nws tsis ua haujlwm zoo, koj tuaj yeem muaj cov ntshav txhaws uas tshwm sim tas li, zoo li lub dab da dej ntws tawm. Qhov no yog vim li cas koj thiaj li muaj kev pheej hmoo ntawm kev tsim cov ntshav txhaws tsis zoo .

Cov neeg uas muaj tus mob no muaj feem yuav mob ntshav txhaws hauv cov leeg ntshav tob ntawm ob txhais ceg ('Deep Vein Thrombosis' lossis 'DVT') thiab muaj feem yuav mob ntshav txhaws tawg thiab daig hauv cov leeg ntshav hauv lub ntsws ('Pulmonary Embolism' lossis 'PE') . Cov no yog cov mob txaus ntshai heev.

Tus mob no feem ntau tshwm sim li cas?

Qhov tsis txaus ntawm cov tshuaj Antithrombin yog ib qho mob uas tsis tshua muaj . Kwv yees li ntawm 2,000 txog 3,000 tus neeg tsuas muaj ib tus xwb. Qhov ntawd tsis tau txhais hais tias nws tsis tshwm sim rau txhua tus.

Cov tsos mob ntawm qhov tsis muaj antithrombin yog dab tsi?

Tsis yog txhua tus neeg uas muaj tus mob no yuav muaj cov tsos mob zoo ib yam. Tej zaum ib txhia neeg yuav tsis muaj cov tsos mob li. Txawm li cas los xij, feem ntau cov ntshav txhaws thawj zaug tshwm sim ua ntej hnub nyoog 40 xyoo .

Cov tsos mob feem ntau pom yog:

• Kab mob ntshav hauv cov hlab ntsha tob (DVT): Qhov no tuaj yeem ua rau ceg o, liab, mob, thiab sov so thaum kov.
• Kab Mob Ntsws Plawv (PE): Qhov no ua rau ua pa luv luv tam sim ntawd, mob hauv siab (tshwj xeeb tshaj yog thaum ua pa), ua pa sai, hnoos (qee zaum muaj ntshav), thiab ua pa luv luv. Qhov no yog ib qho mob uas xav tau kev kho mob ceev.

Ntxiv rau cov no, txawm tias tsis tshua muaj, hauv cov hlab ntsha hauv lub hlwb , lossis hauv cov hlab ntsha hauv plabMuaj peev xwm ua rau cov ntshav txhaws.

Vim li cas qhov tsis muaj antithrombin no thiaj tshwm sim?

Feem ntau, qhov ua rau muaj tus mob no yog los ntawm noob caj noob ces , uas txhais tau tias nws yog ib yam dab tsi uas peb tau txais los ntawm peb niam peb txiv.

• Kev Hloov Pauv ntawm Gene: Qhov tsis txaus Antithrombin tshwm sim rau cov neeg uas muaj kev hloov pauv (kev hloov pauv) hauv cov gene hu ua 'SERPINC1'. Cov gene no qhia kom lub cev tsim cov antithrombin.
• Kev Txais Yuav: Koj tuaj yeem tau txais qhov kev hloov pauv ntawm cov noob caj noob ces no los ntawm niam txiv ib leeg. Yog tias yog, koj muaj 50% feem pua ​​​​​​ntawm kev mob. Nws tsis muaj teeb meem seb nws yog ntxhais lossis tub. Txawm li cas los xij, cov menyuam mos uas tau txais qhov kev hloov pauv ntawm cov noob caj noob ces no los ntawm niam txiv ob leeg feem ntau tsis muaj sia nyob. Qhov no tsis tshua muaj.

Qhov tseem ceeb yog tias tsis yog txhua tus neeg uas muaj qhov kev hloov pauv ntawm cov noob caj noob ces no yuav muaj cov ntshav txhaws. Ib txhia neeg yuav nyob tau tag nrho lawv lub neej yam tsis muaj teeb meem dab tsi.

Cov kws kho mob paub qhov no li cas?

Yog koj muaj cov tsos mob no, lossis paub tias ib tug neeg hauv koj tsev neeg muaj tus mob no, nws yog ib lub tswv yim zoo mus ntsib kws kho mob thiab mus kuaj mob. Tus kws kho mob feem ntau yuav ua cov hauv qab no:

• Kev kuaj lub cev: Koj lub cev yuav raug kuaj.
• Keeb kwm kho mob: Koj yuav raug nug txog koj cov tsos mob thiab seb puas muaj leej twg hauv koj tsev neeg tau muaj teeb meem zoo sib xws.
• Kev kuaj ntshav: Qhov tseem ceeb tshaj plaws yog kom muaj kev kuaj ntshav tshwj xeeb uas kuaj xyuas qib antithrombin hauv koj cov ntshav.

Cov kev kuaj no yog tib txoj kev los paub tseeb tias qhov mob no muaj los tsis muaj.

Koj ua dab tsi li kev kho mob?

Kev kho mob nyob ntawm seb koj puas muaj ntshav txhaws los tsis muaj.

• Yog koj muaj cov ntshav txhaws: Koj tus kws kho mob yuav txiav txim siab pib noj tshuaj thinning ntshav rau koj. Qhov no feem ntau yog warfarin (tej zaum koj yuav tau hnov ​​​​​​txog nws li Coumadin). Qhov no yuav siv sijhawm ntau lub hlis, lossis nws yuav siv sijhawm tas mus li.
• Yog tias koj yeej tsis tau muaj ntshav txhaws: Txawm tias koj muaj antithrombin deficiency los xij, yog tias koj yeej tsis tau muaj ntshav txhaws, feem ntau koj tsis tas yuav noj cov tshuaj thinning ntshav ntxiv lawm. Txawm li cas los xij, qee zaum (piv txwv li, ua ntej phais loj) lawv yuav raug muab rau lub sijhawm luv luv.
• Thaum cev xeeb tub: Vim tias ntawm 3% thiab 50% ntawm cov poj niam cev xeeb tub uas muaj tus mob no tuaj yeem tsim cov ntshav txhaws thaum cev xeeb tub, tus kws kho mob yuav txiav txim siab muab tshuaj txhaj tshuaj hu ua 'Heparin' los tiv thaiv cov ntshav txhaws thaum lub sijhawm ntawd.

Kuv yuav tsum saib xyuas kuv tus kheej li cas? (Thaum kuv tab tom kho mob)

Yog koj noj cov tshuaj ua kom cov ntshav nyias xws li Warfarin lossis Heparin, nws yog ib qho tseem ceeb heev uas yuav tsum noj cov tshuaj raws nraim li koj tus kws kho mob qhia rau koj.Tsis tas li ntawd, nco ntsoov mus rau txhua qhov teem sijhawm uas koj muaj nrog tus kws kho mob.

Vim tias cov tshuaj no muaj kev pheej hmoo ntawm kev los ntshav, koj tus kws kho mob yuav tsum xyuas kom koj tau txais cov koob tshuaj raug. Cov kev kuaj ntshav xws li 'Prothrombin Time' (PT) yog siv los xyuas seb cov koob tshuaj Warfarin puas raug.

Los ntawm kev tswj cov tshuaj kom raug raws li txoj kev no, cov ntshav txhaws txaus ntshai tuaj yeem tiv thaiv tau thiab kev los ntshav tsis tsim nyog tuaj yeem tiv thaiv tau.

Kuv ua tau dab tsi los txo qhov kev pheej hmoo ntawm cov ntshav txhaws?

Yog tias koj muaj qhov tsis txaus antithrombin, muaj ntau yam koj tuaj yeem ua tau los txo koj qhov kev pheej hmoo ntawm cov ntshav txhaws:

• Tsis txhob noj cov tshuaj tiv thaiv kev yug me nyuam: tshwj xeeb tshaj yog cov uas muaj estrogen. Tham nrog koj tus kws kho mob txog qhov no.
• Tsis txhob siv tshuaj hormones: Qee cov tshuaj hormones uas siv tom qab lub sijhawm tas lawm kuj tuaj yeem ua rau muaj kev pheej hmoo ntau ntxiv.
• Tsis txhob nyob hauv tib qho chaw ntev dhau: Tshwj xeeb tshaj yog thaum mus ncig deb lossis ua haujlwm hauv ib qho chaw ntev dhau, sawv tsawg kawg txhua ob teev thiab taug kev ncig me ntsis thiab co koj ob txhais ceg.
• Tsis txhob haus luam yeeb thiab siv cov khoom luam yeeb: Kev haus luam yeeb ua rau cov hlab ntsha puas tsuaj heev thiab ua rau muaj kev pheej hmoo ntawm cov ntshav txhaws.
• Tswj kom muaj qhov hnyav noj qab nyob zoo: Kev rog dhau yog lwm yam ua rau cov ntshav txhaws.

Ntxiv mus, tej yam xws li kev raug mob loj, kev phais, cev xeeb tub, yug menyuam, thiab kev laus kuj ua rau koj muaj feem yuav ntshav txhaws. Yog tias koj xav tau kev phais lossis tab tom yuav muaj menyuam, qhia rau koj tus kws kho mob txog koj tus mob. Nws yuav muab cov tshuaj antithrombin concentrate tshwj xeeb rau koj ua cov tshuaj txhaj rau hauv cov hlab ntsha (IV), yog tias xav tau.

Puas muaj ib txoj kev los tiv thaiv qhov teeb meem no kom tsis txhob tshwm sim?

Tu siab kawg li, vim nws yog ib yam mob uas muaj los ntawm noob caj ces, tsis muaj ib txoj hauv kev los tiv thaiv qhov tsis txaus antithrombin uas tau txais los ntawm noob caj ces. Peb tsis tuaj yeem hloov cov noob caj ces uas peb tau txais los ntawm peb niam peb txiv. Txawm li cas los xij, muaj tej yam uas peb ua tau los txo peb txoj kev pheej hmoo ntawm cov ntshav txhaws.

Yog tias koj muaj antithrombin deficiency, yuav tsum xav li cas?

Kwv yees li ib ntawm peb tus neeg uas muaj tus mob no yuav muaj cov ntshav txhaws thaum lawv laus.

• Kev Phais Mob thiab Kev Tsis Txav Mus Los: Yog tias koj tab tom phais mob thiab tsis txav mus los ntev (piv txwv li, yog tias koj yuav tsum pw hauv txaj), koj muaj feem yuav muaj ntshav txhaws ntau dua.
• Kev laus: Qhov kev pheej hmoo no kuj nce me ntsis nrog hnub nyoog.
• Cev Xeeb Tub: Cov neeg uas muaj antithrombin deficiency yuav muaj cov ntshav txhaws tsis zoo thaum cev xeeb tub lossis tom qab yug menyuam, yog li yuav tsum tau ua tib zoo saib xyuas qhov no.

Qhov xwm txheej no yuav kav ntev npaum li cas?

Vim tias nws yog ib yam mob caj ces, koj yug los nrog nws. Nws yog ib yam dab tsi uas kav ntev mus ib sim neej. Qhov ntawd txhais tau tias nws tsis tuaj yeem kho tau tag nrho. Tab sis, yog tias tswj hwm kom zoo, koj tuaj yeem nyob nrog tsawg dua teeb meem.

Qhov xwm txheej no yuav zoo li cas?

Koj txoj kev xav nyob ntawm seb koj puas tau muaj ntshav txhaws los tsis tau. Kev noj tshuaj uas ua rau cov ntshav nyias tuaj yeem pab tiv thaiv kom tsis txhob muaj ntshav txhaws ntxiv. Txawm li cas los xij, nws yog ib qho tseem ceeb uas yuav tsum noj tshuaj raws nraim li koj tus kws kho mob qhia rau koj, noj raws li qhov ntau npaum li cas, thiab siv sijhawm kom raug.

Kuv yuav tsum ceev faj txog dab tsi?

Yog tias koj muaj qhov tsis txaus antithrombin, nws yog ib qho tseem ceeb kom paub txog cov cim ceeb toom ntawm 'DVT' (cov ntshav txhaws hauv ceg) thiab 'PE' (cov ntshav txhaws hauv lub ntsws) kom koj thiaj li tau txais kev pab sai.

• Cov tsos mob ntawm DVT: o, mob, liab, thiab sov so rau ntawm ib ceg (feem ntau tsuas yog ib ceg xwb).
• Cov tsos mob ntawm PE: Ua pa luv luv tam sim ntawd, mob hauv siab (uas ua rau mob hnyav dua thaum ua pa), ua pa sai, ua pa luv luv, hnoos (qee zaum muaj ntshav).

Yog koj noj cov tshuaj ua kom cov ntshav nyias (piv txwv li Warfarin), ceev faj txog cov hauv qab no vim tias muaj kev pheej hmoo ntawm kev los ntshav:

• Ceev faj heev thaum siv cov riam phom ntse (riam, rab chais, thiab lwm yam)
• Tsis txhob ua si nawv uas yuav ua rau raug mob (piv txwv li, ntaus pob rugby, ntaus nrig ntaus nrig) ​​ntau li ntau tau. Yog tsis ua li ntawd, hnav cov khoom siv tiv thaiv kom zoo.
• Yog tias qhov ntshav tsis tu txawm tias yog los ntawm ib qho qhov txhab yooj yim xwb los xij, lossis yog tias koj muaj cov qhov txhab tsis muaj laj thawj, qhia rau koj tus kws kho mob.

Kuv yuav tsum mus ntsib kws kho mob thaum twg?

Yog koj xav tias koj muaj DVT, mus ntsib kws kho mob tam sim ntawd. Nws yog ib qho tseem ceeb uas yuav tsum kho DVT sai sai, vim tias cov ntshav txhaws hauv ceg tuaj yeem tawg thiab mus rau hauv lub ntsws, ua rau PE.

Yog koj noj tshuaj xws li Warfarin, qhia rau koj tus kws kho mob tam sim ntawd yog tias koj ntog lossis yog tias koj los ntshav txawv txawv (piv txwv li, los ntawm koj lub qhov ntswg, cov pos hniav, lossis cov quav).

Thaum twg koj yuav tsum mus rau Chav Kho Mob Thaum Muaj Xwm Ceev (ETU) ?

Yog li ntawd , koj yuav tsum mus rau chav kho mob ceev (ETU) ntawm tsev kho mob tam sim ntawd:

• Yog koj muaj cov tsos mob ntawm 'Pulmonary Embolism (PE)' (xws li ua pa luv luv tam sim ntawd, mob hauv siab).
• Yog tias koj xav tias koj muaj cov tsos mob ntawm DVT , tab sis koj tsis tuaj yeem tiv tauj koj tus kws kho mob?
• Yog tias koj noj tshuaj ua kom cov ntshav nyias, yog tias koj ntaus koj lub taub hau, yog tias koj ntuav ntshav, lossis yog tias koj tsis tuaj yeem tso tseg qhov ntshav ntawm qhov txhab.

Cov no yog cov xwm txheej ceev uas hem txoj sia, yog li ntawd tsis txhob ncua sijhawm.

Cov lus nug tseem ceeb uas kuv yuav tsum nug kuv tus kws kho mob yog dab tsi?

Thaum koj paub tias koj muaj tus mob no, koj tuaj yeem nug koj tus kws kho mob cov lus nug zoo li no:

• Kuv puas yuav tsum tau noj Warfarin los yog lwm yam tshuaj uas ua rau cov ntshav nyias? Kuv yuav tsum tau noj ntev npaum li cas?
• Puas yog ib lub tswv yim zoo kom coj lwm tus tswv cuab hauv kuv tsev neeg (niam txiv, cov kwv tij neej tsa, cov menyuam) mus kuaj seb puas muaj Antithrombin Deficiency?
• Kuv ua tau cov kev tawm dag zog twg kom muaj kev nyab xeeb nrog tus mob no?
• Puas muaj tej yam tshwj xeeb uas kuv yuav tsum paub ua ntej kuv cev xeeb tub?

Nug cov lus nug zoo li no kom nkag siab zoo dua txog koj qhov xwm txheej.

Thaum kawg, tej yam koj yuav tsum nco ntsoov (Cov Lus Coj Mus Tsev)

Vim tias Antithrombin Deficiency yog ib yam mob uas los ntawm noob caj noob ces, peb tswj tsis tau nws. Txawm li cas los xij, los ntawm kev paub txog qhov mob no thiab ua cov kauj ruam tsim nyog, koj tuaj yeem ua lub neej noj qab haus huv zoo dua.

Qhov tseem ceeb tshaj plaws yog rau koj thiab koj tsev neeg kom paub cov cim ceeb toom ntawm DVT thiab PE kom yog tias muaj qee yam tsis raug, koj tuaj yeem paub nws thaum ntxov thiab nrhiav kev kho mob sai.

Kev tswj koj qhov hnyav, ua kom koj lub cev nquag (ua si tsis tu ncua), thiab tsis txhob haus luam yeeb tuaj yeem pab koj txo qhov kev pheej hmoo ntawm kev tsim cov ntshav txhaws tsis xav tau. Ua li no, koj tuaj yeem tswj tau qhov cuam tshuam ntawm qhov mob no rau koj lub neej rau qee qhov. Tham nrog koj tus kws kho mob tsis tu ncua thiab ua raws li nws cov lus qhia kom zoo. Tsis txhob txhawj, koj tsis nyob ib leeg!

Tsis muaj antithrombin txaus, ntshav txhaws, DVT, pulmonary embolism, cov kab mob caj ces, ntshav thinner, warfarin, heparin