Koj tus me nyuam puas kub taub hau, mob qhov ncauj, lossis mob caj pas rau tib hnub txhua hli? Puas muaj ib qho mob ploj mus, tsuas yog rov qab los ob lossis peb lub lis piam tom qab? Tej zaum koj yuav xav tias, "Kuv tus menyuam lub cev tiv thaiv kab mob tsis muaj zog." Yog lawm, qhov ntawd yuav muaj tseeb. Tab sis qhov laj thawj tom qab qhov mob no yuav yog ib qho mob tsis tshua muaj. Niaj hnub no, peb tab tom tham txog ib qho mob zoo li no, cyclic neutropenia.
Hais yooj yim xwb, cyclic neutropenia yog dab tsi?
Yuav kom nkag siab qhov no, peb yuav tsum paub txog ib tug tub rog hauv peb cov ntshav ua ntej. Tus tub rog ntawd lub npe yog neutrophil . Cov neutrophil no yog ib hom qe ntshav dawb uas tiv thaiv peb ntawm kab mob los ntawm kev tawm tsam cov kab mob, tshwj xeeb tshaj yog cov kab mob me me, uas nkag mus rau hauv peb lub cev. Nws zoo li ib pab tub rog hauv peb lub cev.
Neutropenia yog thaum tus naj npawb ntawm cov tub rog neutrophil hauv cov ntshav poob qis dua qib ib txwm. Ib yam li ib pab tub rog qaug zog thaum nws cov tub rog tsawg dua, thaum neutrophils tsawg dua, peb lub cev tiv thaiv kab mob qaug zog dua thiab peb pib kis kab mob yooj yim dua.
Tam sim no cia peb saib lub ntsiab lus ntawm lo lus cyclic . Cyclic txhais tau tias "cyclical." Qhov no txhais tau tias qib neutrophil tsis yog qis tas li. Nws nce thiab nqis raws li lub sijhawm tsis tu ncua, hauv ib lub voj voog. Yog xav kom meej, feem ntau txhua peb lub lis piam (kwv yees li 21 hnub) , qib neutrophil poob qis heev rau peb txog tsib hnub. Tom qab ntawd nws rov qab mus rau qhov qub, thiab tom qab ntawd poob dua rau peb lub lis piam tom ntej. Lub voj voog no tshwm sim hauv txoj kev kwv yees tau zoo heev.
Hais yooj yim xwb, cyclic neutropenia yog ib qho mob uas tus lej ntawm cov hlwb neutrophil, uas tiv thaiv peb lub cev ntawm kab mob, txo qis raws li lub voj voog txhua hnub, ua rau muaj kev pheej hmoo ntawm kev kis kab mob.
Tus mob no tsis tshua muaj. Cov kws tshawb fawb hais tias tsuas muaj ib tug ntawm ib lab tus tib neeg hauv ntiaj teb no uas muaj tus kab mob no.
Cov tsos mob ntawm tus kab mob no yog dab tsi?
Qhov tshwj xeeb ntawm tus kab mob no yog tias cov tsos mob tshwm sim raws li lub voj voog ntawm kev txo qis ntawm cov neutrophils. Uas yog, cov tsos mob no tshwm sim hauv peb mus rau plaub hnub ntawm kev txo qis ntawm cov neutrophils, thiab thaum cov neutrophils rov qab mus rau qhov qub, cov tsos mob ploj mus.
| Cov tsos mob | Kev piav qhia |
|---|---|
| Kub taub hau thiab qaug zog | Thaum cov neutrophils qis, thawj qhov cim qhia tias muaj kev kis kab mob hauv lub cev yuav yog kub taub hau. Nrog rau qhov no, lub cev yuav xav tias tsis muaj sia nyob. |
| Mob qhov ncauj thiab mob caj pas | Qhov no yog ib qho tsos mob uas pom ntau heev. Nws tuaj yeem ua rau mob hauv qhov ncauj thiab ntawm cov pos hniav. Nws kuj tseem tuaj yeem ua rau mob caj pas. |
| Kab mob ntawm cov pos hniav | Tej zaum yuav muaj ntshav thiab o ntawm cov pos hniav ntau zaus. |
| Cov kab mob rov tshwm sim | Cov kab mob hauv txoj hlab pa (mob khaub thuas, hnoos), cov kab mob hauv txoj hnyuv (mob plab), thiab cov kab mob ntawm daim tawv nqaij (cellulitis) tuaj yeem tshwm sim ntau zaus. |
Cov tsos mob no tuaj yeem hloov pauv thoob plaws lub neej. Rau ntau tus neeg, qhov hnyav ntawm cov tsos mob yuav txo qis thaum lawv mus txog hnub nyoog laus . Mob qhov ncauj thiab teeb meem hniav feem ntau tshwm sim rau cov tub ntxhais hluas, thaum mob taub hau thiab mob sinusitis (sinusitis) feem ntau tshwm sim rau cov neeg laus.
Vim li cas qhov no thiaj tshwm sim?
Qhov ua rau muaj cov qe ntshav dawb tsis txaus (cyclic neutropenia) yog los ntawm kev hloov pauv ntawm cov noob caj noob ces . Qhov ua rau tseem ceeb yog kev hloov pauv ntawm cov noob caj noob ces ELANE hauv peb lub cev.
Xav txog ib tug gene ua ib pawg lus qhia uas qhia cov cell hauv peb lub cev yuav ua haujlwm li cas. Tus gene ELANE muaj cov lus qhia rau kev ua ib qho enzyme uas pab cov neutrophils ua haujlwm kom zoo. Thaum muaj qhov tsis zoo lossis kev hloov pauv hauv tus gene no, cov neutrophils tsis tuaj yeem ua haujlwm kom zoo.
Tus mob no tuaj yeem tau txais los ntawm niam txiv mus rau cov menyuam, lossis nws tuaj yeem tshwm sim thaum lub sijhawm cev xeeb tub.
Vim yog qhov teeb meem caj ces no,
- Lub cev yuav tsis tsim cov neutrophils txaus.
- Txwv tsis pub, cov neutrophils yuav tuag sai.
- Los yog cov neutrophils yuav tsis ua haujlwm zoo.
Kws kho mob, koj kuaj qhov no li cas?
Cov tsos mob no feem ntau pom tau txij thaum yug los, yog li ntawd feem ntau kuaj pom tus kab mob thaum yau. Tus kws kho mob yuav xav txog ntau yam los paub meej tias tus kab mob no yog dab tsi.
- Keeb kwm tsev neeg muaj tus kab mob no: Vim tias qhov no yog ib qho mob uas tau los ntawm noob caj ces, nws raug kuaj xyuas seb puas muaj lwm tus neeg hauv tsev neeg (niam txiv, cov kwv tij neej tsa) muaj tus kab mob no.
- Kev kuaj ntshav: Qhov no yog qhov tseem ceeb tshaj plaws. Koj tus kws kho mob yuav kuaj koj cov neutrophil hauv koj cov ntshav ob mus rau peb zaug hauv ib lub lim tiam rau li rau lub lim tiam . Qhov no yuav ua kom pom tias koj cov neutrophil puas txo qis.
- Tus qauv ntawm cov tsos mob: Tus kws kho mob yuav ua tib zoo kawm txog qhov zaus ntawm cov tsos mob (kwv yees li txhua 3 lub lis piam). Tus qauv voj voog no pab kom paub qhov txawv ntawm lwm hom neutropenia.
- Kev kuaj noob caj noob ces: Qee zaum kev kuaj noob caj noob ces yuav raug pom zoo kom paub tseeb tias puas muaj kev hloov pauv hauv ELANE gene.
Thaum kuaj mob no, tus kws kho mob yuav tsum tsis txhob muaj lwm hom neutropenia uas muaj cov tsos mob zoo sib xws, xws li 'Severe congenital neutropenia' (yav tas los hu ua 'Kostmann syndrome'), 'Autoimmune neutropenia', thiab 'Idiopathic neutropenia'.
Cov kev kho mob rau qhov no yog dab tsi?
Muaj ob lub hom phiaj tseem ceeb ntawm kev kho mob. Ib qho yog kho cov kab mob uas twb muaj lawm. Qhov thib ob yog kom nce cov neutrophils thiab tiv thaiv kev kis kab mob yav tom ntej.
| Txoj kev kho mob | Kev ua haujlwm |
|---|---|
| Cov tshuaj tua kab mob | Cov no yog muab los tua cov kab mob bacterial uas tshwm sim thaum lub sijhawm uas cov neutrophils qis. |
| Kev kho mob G-CSF | Qhov no yog txoj kev kho mob tseem ceeb thiab zoo tshaj plaws. G-CSF (Granulocyte colony-stimulating factor) yog ib yam tshuaj uas ua rau peb cov pob txha tsim cov neutrophils ntau dua (piv txwv li filgrastim (Neupogen®)). Nws yog muab ua ib qho kev txhaj tshuaj thiab yog ib qho kev kho mob zoo uas siv tau ntev. |
| Kev hloov pauv ntawm cov hlwb | Qhov no yog ib txoj kev siv rau cov neeg uas muaj mob hnyav heev thiab cov neeg uas tsis teb rau kev kho mob G-CSF. Hauv txoj kev no, cov hlwb noob noj qab haus huv raug hloov mus hloov cov hlwb uas muaj mob. |
Puas muaj tej yam tshwm sim ntawm kev kho mob?
Kev kho mob G-CSF tuaj yeem ua rau muaj cov kev mob tshwm sim me me. Txawm li cas los xij, cov kws kho mob feem ntau pib kho tus kab mob no nrog cov koob tshuaj tsawg, yog li cov kev mob tshwm sim tsawg heev.
- Mob taub hau
- Mob hauv cov pob txha thiab cov pob qij txha
- Xeev siab thiab raws plab
Tej yam zoo li no yuav tshwm sim tau. Tham nrog koj tus kws kho mob kom zoo zoo txog kev kho mob uas koj tau txais thiab nws cov kev mob tshwm sim.
Kuv yuav tsum hu rau kws kho mob thaum twg?
Yog tias koj lossis koj tus menyuam muaj cyclic neutropenia, nws yog ib qho tseem ceeb heev uas yuav tsum nrhiav kev pab kho mob sai li sai tau thaum koj pom muaj cov cim qhia txog kev kis kab mob .
Ua tib zoo saib xyuas cov yam ntxwv hauv qab no:
* Ua npaws
* Mob qhov twg hauv lub cev
* O los yog liab ntawm daim tawv nqaij
Yog koj pom ib qho ntawm cov cim no, mus ntsib koj tus kws kho mob tam sim ntawd. Tsis txhob yig mus rau Chav Kho Mob Thaum Muaj Xwm Ceev (ETU) yog tias tsim nyog.
Peb yuav tsum ua li cas los tiv thaiv peb tus kheej ntawm kev kis kab mob?
Ntxiv rau kev tiv thaiv koj tus kheej ntawm kev kis kab mob, koj kuj yuav tsum ceev faj thaum koj cov neutrophil suav qis.
- Ntxuav koj txhais tes kom huv si, tshwj xeeb tshaj yog ua ntej noj mov thiab tom qab siv chav dej.
- Tswj kom koj lub qhov ncauj noj qab nyob zoo. Txhuam koj cov hniav txhua hnub thiab mus ntsib kws kho hniav tsis tu ncua .
- Tau txais txhua yam kev txhaj tshuaj tiv thaiv kab mob raws sijhawm.
- Tsis txhob kov koj lub ntsej muag, qhov muag, thiab qhov ntswg yam tsis tau ntxuav koj txhais tes.
- Noj koj cov tshuaj raws nraim li koj tus kws kho mob tau hais thiab kuaj ntshav raws sijhawm.
Txawm hais tias qhov mob no yog ib qho mob uas yuav kho tau mus ib txhis, kev kho mob zoo li G-CSF tam sim no tau tso cai rau ntau tus neeg uas muaj cyclic neutropenia kom ua neej nyob li qub . Qhov tseem ceeb, thaum qee hom neutropenia muaj kev pheej hmoo ntawm kev mob qog noj ntshav, xws li leukemia, cyclic neutropenia tsis muaj.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Cyclic neutropenia yog ib qho mob caj ces tsis tshua muaj uas tus lej ntawm cov hlwb neutrophil uas tawm tsam kev kis kab mob txo qis.
- Cov tsos mob (kub taub hau, mob qhov ncauj) feem ntau tshwm sim li ib zaug txhua 3 lub lis piam.
- Txhawm rau kuaj mob, yuav tsum tau kuaj ntshav tas li rau ob peb lub lis piam kom paub tseeb tias cov neutrophils nyob li qub.
- Vim muaj cov kev kho mob zoo heev xws li G-CSF, cov neeg mob tuaj yeem ua neej nyob li qub.
- Nws yog ib qho tseem ceeb heev uas yuav tsum nrhiav kev pab kho mob sai li sai tau thaum koj pom muaj cov cim qhia txog kev kis kab mob (kub taub hau, mob, o).
💬 Comments (0)
Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus