Koj puas tau xav txog seb peb cov ntshav qab zib raug tswj li cas? Muaj ib yam tshwj xeeb uas pab nrog qhov no hu ua Glucagon. Zoo li ib tug phab ej me me hauv peb lub cev, Glucagon ua rau peb cov ntshav qab zib tsis txhob qis dhau. Hnub no, peb yuav tham txog Glucagon no kom meej thiab yooj yim heev.
Glucagon yog dab tsi?
Hais yooj yim xwb, glucagon yog ib yam tshuaj hormones uas peb lub cev tsim tawm . Koj paub, nws yog tsim los ntawm cov hlwb alpha hauv peb lub pancreas. Thaum peb cov ntshav qab zib poob qis, thaum peb tsis noj mov ntev (yoo mov ntev), thaum peb tawm dag zog hnyav, lossis thaum peb noj zaub mov uas muaj protein ntau, glucagon no raug tso tawm.
Xav txog nws, glucose yog hom qab zib tseem ceeb hauv peb cov ntshav. Peb tau txais cov glucose no los ntawm cov carbohydrates hauv cov khoom peb noj thiab haus. Cov qab zib no yog qhov muab lub zog rau peb lub cev cov kabmob, cov leeg, thiab lub paj hlwb. Nws zoo li roj av rau lub tsheb. Yog li, peb lub cev feem ntau khaws cov ntshav qab zib no rau ntawm qib zoo hauv txoj kev nyuaj heev. Txawm tias qhov no siab dhau lossis qis dhau, ntau yam kab mob thiab kev tsis xis nyob tuaj yeem tshwm sim.
Kev txhaj tshuaj Glucagon thiab tshuaj tsuag rau qhov ntswg
Ntxiv rau cov glucagon uas muaj nyob hauv ntuj, kuj muaj cov glucagon uas tsim los ntawm cov tshuaj. Cov no tuaj yeem muab ua tshuaj txhaj lossis ua tshuaj tsuag rau qhov ntswg qhuav. Tej zaum koj yuav tau pom qhov no siv rau thaum muaj xwm txheej ceev, tshwj xeeb tshaj yog rau cov neeg uas muaj ntshav qab zib hom 1 , thaum lawv cov ntshav qab zib poob qis dhau (hypoglycemia). Cov glucagon uas muab rau lub sijhawm no tso tawm cov glucose uas khaws cia rau hauv peb lub siab thiab ua rau peb cov ntshav qab zib nce sai sai. Nws zoo li muab me ntsis 'txhawb nqa' rau peb.
Glucagon ua dab tsi rau peb lub cev?
Yog tias koj lub qog ua haujlwm zoo, koj lub cev yuav ua tib zoo tswj koj cov ntshav qab zib. Qhov no feem ntau yog ua los ntawm ob lub tshuaj hormones hu ua glucagon thiab insulin . Piv txwv li, thaum koj cov ntshav qab zib qis dhau (hypoglycemia), koj lub qog tso glucagon ntau dua. Cov glucagon no pab ua kom koj cov ntshav qab zib nce ntau txoj hauv kev:
- Ua ntej, glucagon mus rau peb lub siab thiab hloov cov glucose uas khaws cia rau ntawd - uas peb hu ua glycogen - mus ua ib yam dab tsi uas peb siv tau. Tom qab ntawd lub siab mam li tso nws mus rau hauv cov ntshav.
- Qhov thib ob, glucagon tuaj yeem tiv thaiv lub siab kom tsis txhob noj thiab khaws cov piam thaj, ua rau muaj piam thaj ntau ntxiv hauv cov ntshav.
- Qhov thib peb, cov amino acidsGlucagon kuj pab lub cev ua cov piam thaj los ntawm lwm qhov chaw.
Nco ntsoov, nws zoo li lub tshuab ua si seesaw. Thaum cov ntshav qab zib poob qis, glucagon ua haujlwm, thiab thaum cov ntshav qab zib nce siab, insulin ua haujlwm!
Cov kab mob twg yuav cuam tshuam nrog teeb meem nrog kev ua haujlwm ntawm glucagon?
Tam sim no cia peb saib seb muaj teeb meem dab tsi tshwm sim yog tias glucagon tsis ua haujlwm zoo.
Yog tias koj muaj ntshav qab zib, koj lub cev yuav tsis muaj peev xwm tso glucagon txaus thaum koj cov ntshav qab zib qis. Qhov no tuaj yeem ua rau koj muaj feem yuav muaj ntshav qab zib qis ntau zaus, lossis txawm tias ntshav qab zib qis heev . Qhov kev pheej hmoo no yog qhov siab tshwj xeeb yog tias koj noj cov tshuaj txo cov ntshav qab zib xws li insulin lossis sulfonylureas.
Rau qee tus neeg uas muaj ntshav qab zib hom 2, cov glucagon yuav siab dua li qub, piv rau cov ntshav qab zib. Qhov no kuj yog ib qho laj thawj uas ua rau cov ntshav qab zib siab.
Nws tsis tshua muaj teeb meem nrog glucagon tsim tawm yam tsis muaj ntshav qab zib, tab sis muaj ob peb qhov xwm txheej uas nws tuaj yeem tshwm sim:
- Mob Pancreatitis: Yog tias koj muaj mob ntshav qab zib vim yog mob pancreatitis thiab noj tshuaj insulin rau nws, koj kuj tseem yuav muaj qhov tsis txaus glucagon. Qhov no ua rau muaj kev pheej hmoo ntawm cov ntshav qab zib qis.
- Glucagonoma: Qhov no yog ib qho mob qog nqaij hlav ntawm lub txiav pancreas uas tsis tshua muaj. Nws tso tawm glucagon ntau dhau. Qhov no ua rau muaj cov tsos mob xws li ntshav qab zib ntau, tawv nqaij tawm pob, thiab poob phaus.
- Multiple Endocrine Neoplasia (MEN): Qhov no kuj yog ib qho mob caj ces tsis tshua muaj. Hauv qhov no, cov qog tsim ntau dua ib lub qog hauv koj lub endocrine system. Qhov no suav nrog lub pancreas.
- Cov kev mob tshwm sim ntawm kev phais mob pancreatectomy: Yog tias vim qee qhov laj thawj ib feem lossis tag nrho koj lub pancreas raug tshem tawm, cov hlwb uas tsim glucagon thiab insulin yuav ploj mus.
Cov tsos mob ntawm cov teeb meem ntsig txog glucagon yog dab tsi?
Zoo li peb tau tham ua ntej lawm, qhov tsis zoo ntawm cov glucagon tuaj yeem ua rau cov ntshav qab zib qis (hypoglycemia) lossis cov ntshav qab zib siab (hyperglycemia). Cia peb saib seb cov tsos mob ntawd yog dab tsi.
Cov tsos mob ntawm cov ntshav qab zib qis (Hypoglycemia)
Xav txog koj tus phooj ywg, Nilanthi, noj tshuaj kho mob ntshav qab zib. Muaj ib hnub, nws mam li pib tshee hnyo, tawm hws, thiab kiv taub hau. Nws kuj zoo li hais lus tsis meej thaum nws hais lus. Yog tias cov tsos mob no tshwm sim, nws txhais tau tias nws cov ntshav qab zib qis heev.
Cov tsos mob feem ntau muaj xws li:
- Co, tshee hnyo
- Tawm hws thiab xav tias txias
- Kiv taub hau, xav tias lub taub hau me me
- Lub plawv dhia ceev
- Kev tshaib plab
- Nyuaj siab xav txog, tsis meej pem
Tseem Ceeb: Yog tias koj muaj cov tsos mob no, nws yog ib qho tseem ceeb heev uas yuav tsum noj ib yam dab tsi qab zib, ib yam khoom noj uas muaj carbohydrate ntau lossis dej haus sai li sai tau . Qhov no yuav pab koj cov ntshav qab zib rov qab mus rau qhov qub. Yog tias koj muaj cov tsos mob no ntau zaus, koj yuav tsum mus ntsib koj tus kws kho mob.
Cov tsos mob ntawm cov ntshav qab zib siab (Hyperglycemia)
Ntshav qab zib ntau (hyperglycemia) feem ntau yog tshwm sim los ntawm qhov tsis muaj insulin, tsis yog teeb meem nrog glucagon xwb. Txawm li cas los xij, cov teeb meem glucagon tsawg tsawg kuj tuaj yeem ua rau ntshav qab zib ntau. Cov cim qhia thawj zaug yog:
- Nqhis dej thiab/lossis tshaib plab ntau zaus
- Pom kev tsis meej
- Tso zis ntau zaus ( tso zis ntau zaus)
- Mob taub hau
Yog koj muaj cov tsos mob no, nws yog ib qho tseem ceeb heev uas yuav tsum mus ntsib kws kho mob.
Yuav ua li cas thiaj kuaj tau cov glucagon?
Yog tias koj muaj tej yam tsos mob, koj tus kws kho mob yuav hais kom koj kuaj ntshav kom ntsuas koj cov glucagon. Hauv qhov kev kuaj no, tus kws kho mob lossis tus nais siv ib rab koob los ntsuas cov ntshav ntawm koj cov leeg ntshav. Tom qab ntawd xa mus rau chav kuaj ntshav kom kuaj.
Cov theem glucagon ib txwm muaj yog dab tsi?
Feem ntau, qhov ntau ntawm glucagon uas peb yuav tsum muaj nyob rau hauv peb cov ntshav yog ntawm 50 thiab 100 picograms ib milliliter (pg/mL) . Ib picogram yog ib trillionth ntawm ib gram! Ib qho me me heev, puas yog?
Tiam sis nco ntsoov, cov nqi ib txwm no yuav txawv me ntsis ntawm ib lub chaw kuaj mob mus rau lwm lub chaw kuaj mob. Lawv kuj tseem yuav txawv nyob ntawm seb koj tau yoo mov ntev npaum li cas thiab koj cov ntshav qab zib yog dab tsi thaum lub sijhawm kuaj. Yog li, ib txwm muab koj cov txiaj ntsig piv rau cov nqi ntawm koj daim ntawv qhia kev kuaj ntshav . Yog tias koj muaj lus nug, nrog koj tus kws kho mob tham.
Thaum twg kuv yuav tsum mus ntsib kws kho mob txog kuv cov glucagon?
Yog tias koj muaj ntshav qab zib thiab koj muaj cov ntshav qab zib qis lossis siab ntau zaus, nws yog ib qho tseem ceeb uas yuav tsum mus ntsib kws kho mob. Cov qib Glucagon feem ntau tsis ntsuas rau cov neeg uas muaj ntshav qab zib. Txawm li cas los xij, koj yuav tsum hloov koj txoj kev tswj ntshav qab zib kom txo cov xwm txheej no.
Txawm hais tias lwm yam teeb meem ntsig txog glucagon tsis tshua muaj, yog tias koj muaj cov tsos mob, nws yog ib qho tseem ceeb kom nrhiav tau qhov ua rau. Yog li, nco ntsoov mus ntsib koj tus kws kho mob.
Qhov txawv ntawm Glucagon thiab Glycogen yog dab tsi?
Ob yam no puas zoo ib yam? Glycogen yog ib hom glucose (qabzib) uas khaws cia rau hauv lub siab.Peb lub cev khaws glycogen feem ntau hauv daim siab thiab cov leeg.
Glucagon yog ib yam tshuaj hormones uas qhia rau lub siab kom hloov glycogen rov qab mus ua glucose. Cov glucose ntawd ces nkag mus rau hauv cov ntshav thiab peb lub cev siv tau ua lub zog.
Yuav ua li cas rau glucagon thaum lub sijhawm yoo mov?
Thaum peb yoo mov, glucagon tseem ceeb heev rau kev ua kom peb cov ntshav qab zib tsis txhob poob qis dhau. Qhov no yog vim peb lub cev tsis tau txais glucose los ntawm cov khoom noj thaum lub sijhawm ntawd.
Thaum peb yoo mov ntev, glucagon ua rau lub cev tsim cov glucose los ntawm cov khoom tsis yog carbohydrate - xws li lipids, amino acids, thiab proteins. Cov txheej txheem no hu ua gluconeogenesis .
Thaum kawg, kuv yuav tsum hais tias... (Cov Lus Coj Mus Tsev)
Yog li, tej zaum koj yuav nkag siab tias glucagon yog ib qho tshuaj hormones tseem ceeb heev uas pab kom peb cov ntshav qab zib noj qab nyob zoo 'tom qab qhov xwm txheej'. Nws tsis zoo li koj muaj ntshav qab zib lossis teeb meem ntsig txog glucagon.
Txawm li cas los xij, yog tias koj muaj cov tsos mob ntawm cov ntshav qab zib qis lossis ntshav qab zib siab, thov mus ntsib koj tus kws kho mob. Lawv mam li nrhiav tau qhov ua rau thiab sau ntawv kho mob uas koj xav tau. Kev saib xyuas koj txoj kev noj qab haus huv yog qhov tseem ceeb tshaj plaws.
👩🏽⚕️ Cov Lus Nug Ntxiv (FAQs)
💬 Glucagon puas yog ib yam tshuaj uas txo cov ntshav qab zib zoo li Insulin?
Tsis yog! Qhov no yog ib yam tshuaj hormones hauv lub cev uas ua haujlwm zoo li 'tus kwv tij phem/sab nraud' ntawm insulin. Insulin yuam kom lub cev cov piam thaj poob qis. Tab sis 'glucagon', thaum lub cev cov piam thaj poob qis heev (Hypoglycemia), yuam kom cov piam thaj khaws cia hauv lub siab (Glycogen) mus rau hauv cov ntshav tam sim ntawd thiab 'ua kom cov piam thaj rov qab mus rau qhov qub'.
💬 Vim li cas cov tshuaj Glucagon hormone no thiaj muaj tau los ntawm lub tsev muag tshuaj ua kev kho mob thaum muaj xwm txheej ceev?
Yog tias tus neeg mob ntshav qab zib noj tshuaj lossis insulin ntau dhau thiab dhau los ua 'qab zib qis hauv cov ntshav / tam sim ntawd tsis nco qab thiab tsis nco qab' (Hypoglycemia), nws tsis tuaj yeem noj qab zib thaum ntawd (nws daig). Tsuas yog thaum ntawd, yog tias 'Glucagon Pen' (kev txhaj tshuaj thaum muaj xwm txheej ceev) raug txhaj rau hauv nws lub ris lossis nws lub duav, cov qab zib hauv lub cev yuav nce ntxiv hauv ob peb feeb thiab tus neeg mob rov qab nco qab.
💬 Puas yooj yim txhaj tshuaj glucagon no hauv tsev?
Yog lawm! Qhov no zoo ib yam li EpiPen rau kev ua xua, thiab muaj nyob rau hauv lub thawv khoom siv thaum muaj xwm txheej ceev uas cov tswv cuab tuaj yeem txhaj tshuaj tau yooj yim hauv tsev. (Hauv qee lub tebchaws, nws kuj muaj ua tshuaj tsuag qhov ntswg / Baqsimi.) Yog tias muaj ib tus neeg nyob hauv tsev uas noj insulin rau ntshav qab zib, nws yog ib qho tseem ceeb heev uas yuav tsum khaws cov tshuaj txhaj glucagon no rau hauv lub tub yees lossis lub txee kom tsis txhob tuag tam sim ntawd.
glucagon , ntshav qab zib, hypoglycemia, hyperglycemia, ntshav qab zib, pancreas, hormone
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus