Koj puas muaj gastrin ntau dhau hauv koj lub plab? Cia peb tham txog (Hypergastrinemia)!

Koj puas feem ntau hnov ​​​​​​mob plab, puv nkaus, lossis lwm yam teeb meem zom zaub mov? Qee zaum qhov laj thawj rau qhov no yuav yog vim qib ntawm cov tshuaj hormones hu ua '(Gastrin)' tsim tawm hauv koj lub cev siab dua li qub. Hnub no, peb yuav tham txog qhov mob no hu ua '(Hypergastrinemia)' kom ntxaws thiab yooj yim heev.

`(Hypergastrinemia)` yog dab tsi? Cia peb nkag siab meej!

Hais yooj yim xwb, '(Hypergastrinemia)' txhais tau hais tias qib ntawm '(Gastrin)', ib yam tshuaj hormones uas pab peb lub cev zom zaub mov, siab dua qhov tsim nyog. Cov tshuaj hormones '(Gastrin)' no yog tsim los ntawm ib hom cell tshwj xeeb hauv phab ntsa plab hauv qab ntawm peb lub plab, uas yog, ze ntawm txoj hnyuv me. Peb hu qhov no '(G cells)'.

Tam sim no saib seb, cov tshuaj hormones '(Gastrin)' no yog qhov qhia rau peb lub plab, "Okay, tam sim no tso cov kua qaub." Cov kua qaub hauv plab no, uas yog '(gastric acid), tseem ceeb heev rau peb. Vim tias, cov kua qaub hauv plab no pab peb zom cov khoom noj uas peb noj thiab nqus cov as-ham hauv cov khoom noj ntawd, piv txwv li '(amino acids)' thiab cov protein.

Txawm li cas los xij, qhov uas yuav tshwm sim nrog '(Hypergastrinemia)' yog qhov nyuaj me ntsis. Qee zaum nws tuaj yeem ua rau muaj kua qaub ntau dhau hauv plab ('hyperchlorhydria'), thiab lwm lub sijhawm nws tuaj yeem ua rau muaj kua qaub tsawg dhau hauv plab ('hypochlorhydria'). Yog li ntawd, '(Hypergastrinemia)' cuam tshuam li cas rau koj nyob ntawm lwm yam mob uas koj muaj, kev phais uas koj tau ua, thiab cov tshuaj uas koj noj.

Leej twg yuav muaj tus mob no ntau dua?

Qhov tseeb, tus mob no hu ua "Hypergastrinemia" tuaj yeem tshwm sim rau txhua tus, tsis hais hnub nyoog lossis poj niam txiv neej. Yog li ntawd, nws yog qhov zoo rau peb txhua tus kom paub txog qhov no.

Dab tsi yog cov ua rau muaj '(Hypergastrinemia)'?

Muaj ntau yam ua rau muaj tus mob no, suav nrog "Hypergastrinemia." Qee yam ua rau cov kua qaub hauv plab tsawg zuj zus, thaum lwm yam ua rau cov kua qaub hauv plab ntau zuj zus. Cia peb saib ob yam sib cais.

Ua rau cov kua qaub hauv plab tsawg dua

Thaum muaj "Hypergastrinemia" tshwm sim, cov kua qaub hauv plab yuav txo qis vim yog cov laj thawj no:

• Cov tshuaj Antacids rau mob plab lossis GERD (Gastroesophageal Reflux Disease): Yog tias koj siv cov tshuaj no tas li , qhov ntawd kuj tuaj yeem yog qhov ua rau.
• Mob plab atrophic ntev: Qhov no yog thaum phab ntsa plab maj mam qaug zog thiab o tuaj raws sijhawm.
• Mob qog nqaij hlav ntawm txoj hnyuv: Qhov no kuj tuaj yeem cuam tshuam.
• Kev kis tus kab mob `(H. pylori): `(Helicobacter pylori)` yog ib hom kab mob uas nyob tau hauv plab. Kev kis tus kab mob no kuj yog ib qho ua rau `(Hypergastrinemia).`
• Kev ua tsis tau haujlwm ntawm lub raum: Qhov mob no tuaj yeem tshwm sim thaum lub raum tsis ua haujlwm zoo.
• Kev Siv Cov Tshuaj Proton Pump Inhibitors (PPIs):Kev siv tshuaj PPI ntev (xws li omeprazole) rau mob gastritis, acid reflux, mob plab zom mov tsis zoo, lossis mob peptic ulcer kuj yog ib qho ua rau mob loj.
• Kev phais vagotomy: Qhov no suav nrog kev tshem tawm ib feem ntawm cov hlab ntsha vagus. Cov hlab ntsha no khiav ntawm lub hlwb mus rau lub plab thiab nqa cov cim mus rau lub plawv thiab lub plab zom mov. Hypergastrinemia tuaj yeem tshwm sim tom qab phais no.

Ua rau muaj kua qaub ntau ntxiv hauv plab

Tam sim no cia peb saib seb dab tsi ua rau muaj cov kua qaub ntau ntxiv hauv plab (Hypergastrinemia):

• Antral G-cell hyperplasia (pseudo-Zollinger-Ellison syndrome / Ps-ZES): Qhov no yog ib qho mob tsis tshua muaj. Nws zoo ib yam li Zollinger-Ellison syndrome, tab sis tsis muaj qog tsim gastrin hauv lub pancreas lossis thawj feem ntawm txoj hnyuv me (duodenum).
• Kev thaiv qhov tawm ntawm lub plab: Qhov mob no tuaj yeem tshwm sim thaum txoj kev hla ntawm lub plab mus rau txoj hnyuv me raug thaiv. Xav txog nws zoo li cov yeeb nkab dej txhaws.
• Mob qog nqaij hlav ntau yam hauv lub cev hom 1 (MEN-1): Qhov mob no ua rau cov qog nqaij hlav hauv lub cev tsim nyob rau hauv cov qog adrenal, cov qog thyroid, lossis cov qog parathyroid.
• Mob antrum uas tseem tshuav: Qhov mob no tuaj yeem tshwm sim yog tias ib daim me me ntawm lub plab qis (antrum) tseem tshuav tom qab phais kom tshem tawm cov qog lossis kho cov qhov txhab.
• Zollinger-Ellison syndrome (ZES): Qhov no yog ib qho mob uas cov qog tsim cov tshuaj hormone gastrin ntau dhau. Qhov mob no (ZES) tuaj yeem ua rau mob plab.

Cov tsos mob ntawm tus mob '(Hypergastrinemia)' yog dab tsi?

Yog koj muaj '(Hypergastrinemia)', koj yuav muaj cov tsos mob zoo li no:

• Mob plab: Tej zaum koj yuav mob plab tas li.
• Mob raws plab ntev: Mob raws plab uas kav ntev li ob peb hnub.
• Cov qog nqaij hlav pancreatic: Cov no tuaj yeem yog cov qog nqaij hlav cancer lossis benign.
• Mob plab: Cov mob uas tshwm sim nrog kev o ntawm lub plab.
• Kab mob plab hnyuv loj heev: o thiab mob heev hauv txoj hlab pas.

Cov kws kho mob kuaj mob li cas?

Yuav kom paub tseeb tias koj lub plab muaj roj ntau ntau, cov kws kho mob yuav tsum txiav txim siab seb koj lub plab tsim cov kua qaub ntau npaum li cas. Lawv kuj ntsuas qib ntawm gastrin hauv koj cov ntshav.

• Ua ntej qhov kev kuaj no, koj tus kws kho mob yuav hais kom koj yoo mov (tsis txhob noj mov) rau ib lub sijhawm .
• Thiab, yog tias koj yog tus neeg siv "(PPI)"Koj yuav tsum tsis txhob noj cov tshuaj ntawd li ib lub lim tiam ua ntej qhov kev kuaj mob.
• Tom qab ntawd, lawv yuav coj koj cov ntshav mus kuaj thiab xyuas koj cov Gastrin. Qee zaum, lawv yuav coj cov ntshav no ntau zaus hauv ib hnub, rau ob peb hnub, kom pom tias koj cov Gastrin puas hloov pauv.

Yog koj tus kws kho mob xav tias muaj hypergastrinemia, lawv yuav kom kuaj ntxiv kom paub tseeb tias tsis muaj lwm yam mob. Cov no suav nrog:

• Kev kuaj mob secretin: Qhov no suav nrog kev muab tshuaj hormones hu ua secretin rau koj, uas yog tsim los ntawm thawj feem ntawm koj txoj hnyuv me (duodenum). Yog tias koj cov gastrin nce siab sai sai, nws yuav yog ib qho cim ntawm Zollinger-Ellison syndrome.
• Kev kuaj pH hauv plab: Qhov no kuaj xyuas cov kua qaub hauv koj lub plab. Yog tias pH tsawg dua 2, nws kuj tseem yuav yog ib qho cim ntawm Zollinger-Ellison syndrome.

Yuav kho tus mob hypergastrinemia li cas?

Kev kho mob rau hypergastrinemia nyob ntawm seb ua li cas.

• Mob qog noj ntshav hauv plab hnyuv loj, kev thaiv txoj hlab pas, kab mob raum, thiab cov mob xws li `(MEN-1)` thiab `(ZES)`: Thaum kho cov mob no (feem ntau yog los ntawm kev phais), cov tsos mob ntawm `(Hypergastrinemia)` kuj ploj mus.
• Atrophic gastritis (ACG) thiab H. pylori kab mob: Cov mob no tuaj yeem kho tau nrog cov tshuaj tua kab mob.
• Cov tshuaj Proton-pump inhibitors (PPIs): Yog tias koj noj PPI, qhov hypergastrinemia feem ntau yuav ploj mus li ntawm tsib mus rau xya hnub tom qab tso tseg cov tshuaj.
• Mob antrum uas tseem tshuav: Kev tshem tawm cov nqaij ntshiv antral uas tseem tshuav nyob rau hauv qab ntawm lub plab tuaj yeem txo cov kua qaub hauv plab uas tsim tawm ntxiv.

Qhov tseem ceeb tshaj plaws yog tham nrog koj tus kws kho mob txog kev kho mob zoo tshaj plaws rau koj tus mob.

Kuv puas txo tau qhov kev pheej hmoo ntawm '(Hypergastrinemia)'?

Yog tias koj siv cov tshuaj antacids lossis PPIs ntev lawm, muaj kev pheej hmoo ntawm kev mob hypergastrinemia. Yog li ntawd, nws yog ib qho tseem ceeb uas yuav tsum tham nrog koj tus kws kho mob txog yuav ua li cas tswj qhov kev pheej hmoo no.

Yog tias kuv muaj '(Hypergastrinemia)', kuv yuav tsum tos li cas? Yuav ua li cas yog tias tsis kho?

Yog tias hypergastrinemia tsis raug kho kom zoo, cov gastrin hauv lub cev tseem siab. Cov kws tshawb fawb xav tias qhov no yuav ua rau cov hlwb qog noj ntshav loj hlob. Piv txwv li:

• Mob qog ntshav: xws li mob leukemia, lymphoma, thiab mob multiple myeloma.
• Mob qog nqaij hlav ntawm txoj hlab pas
• Mob qog nqaij hlav pancreatic

Tsis tas li ntawd xwb, kev mob "Hypergastrinemia" mus sij hawm ntev tuaj yeem ua rau mob qog hauv plab "(gastric carcinoids)" lossis "gastric adenocarcinoma". Muaj ob hom "(gastric carcinoids)":

• Hom I gastric carcinoids: Cov no yog txuam nrog tus mob chronic atrophic gastritis.
• Nws feem ntau tshwm sim rau cov poj niam.
• Nws tuaj yeem pom nyob rau ntau qhov chaw hauv plab.
• Txoj kev pheej hmoo ntawm kev mob qog noj ntshav yog tsawg.
• Hom II mob qog nqaij hlav hauv plab: Cov no cuam tshuam nrog cov mob ZES thiab MEN-1.
• Nws tuaj yeem tshwm sim rau cov txiv neej thiab cov poj niam.
• Nws tuaj yeem pom nyob rau ntau qhov chaw hauv plab.
• Qee zaum nws tuaj yeem hloov mus ua mob qog noj ntshav (ntawm 7% thiab 12%).

Yuav ua li cas rau ib tus neeg uas muaj '(Hypergastrinemia)'?

Tus neeg uas muaj "Hypergastrinemia" yuav muaj teeb meem kev noj qab haus huv yav tom ntej nyob ntawm ntau yam:

• Qhov ua rau muaj tus kab mob.
• Kev kuaj noob caj noob ces.
• Keeb kwm kev noj qab haus huv.
• Kev ua neej.

Txawm li cas los xij, yog tias kho kom zoo, cov neeg uas muaj "Hypergastrinemia" tuaj yeem ua neej nyob li qub.

Kuv muaj '(Hypergastrinemia)', kuv yuav saib xyuas kuv tus kheej li cas?

Yog koj noj tshuaj antacids lossis PPIs ntev heev, nws yog ib qho tseem ceeb uas yuav tsum tau mus kuaj mob tsis tu ncua. Nug koj tus kws kho mob kom tau lus qhia.

Kuv yuav tsum mus ntsib kws kho mob thaum twg?

Yog tias koj muaj cov tsos mob tshiab no, lossis yog tias koj xav tias koj cov tsos mob uas twb muaj lawm zuj zus tuaj, nco ntsoov mus ntsib kws kho mob thiab kuaj xyuas tag nrho.

Tej yam yuav tsum nco ntsoov ua ntej

Zoo ces, cia peb nco ntsoov qhov peb tau tham txog:

• Hypergastrinemia yog qhov nce ntxiv ntawm cov tshuaj hormones gastrin hauv lub cev.
• Cov tshuaj hormone no (Gastrin) cuam tshuam rau cov kua qaub hauv plab (cov kua qaub tuaj yeem nce lossis txo).
• Muaj ntau yam ua rau - xws li '(PPI)' / siv cov tshuaj antacids tas li, '(H. pylori)' kev kis kab mob, gastritis, '(Zollinger-Ellison syndrome)'.
• Cov kws kho mob kuaj pom qhov no los ntawm kev kuaj qib ntawm "Gastrin".
• Kev kho mob yog raws li qhov ua rau muaj teeb meem.
• Tsis txhob tso tseg cov tsos mob, vim tias lawv tuaj yeem loj hlob mus ua qog thiab mob qog noj ntshav yog tias tsis kho! Nrhiav kev pab kho mob tam sim ntawd.

Vam tias koj pom cov ntaub ntawv no muaj txiaj ntsig. Nyob kom noj qab nyob zoo!

` Hypergastrinemia, Gastrin, Cov kua qaub hauv plab, Kev zom zaub mov, Zollinger-Ellison syndrome, H. pylori, PPI, Mob plab, Mob plab o