Koj cov pob txha puas tsis ua haujlwm zoo? Cia peb tham txog myelosuppression!

Koj puas xav tias koj tsis xis nyob, mob tas li, lossis los ntshav txawm tias yog qhov txiav me me xwb los xij, txawm tias koj tab tom kho mob qog noj ntshav lossis lwm yam mob? Tom qab tej yam no, tej zaum yuav muaj myelosuppression , ib qho mob uas cov pob txha tsis ua haujlwm zoo . Tsis txhob txhawj, cia peb tham txog qhov no yooj yim.

Myelosuppression yog dab tsi? Yog hais kom meej, nws puas yog qhov ua rau cov pob txha tsis muaj zog?

Hais yooj yim xwb, yog lawm! Pob txha yog cov nqaij mos mos, zoo li daim ntaub hauv koj cov pob txha. Xav txog nws zoo li peb lub cev lub Hoobkas tsim cov ntshav . Lub Hoobkas no tsim ntau txhiab lab cov qe ntshav liab, cov qe ntshav dawb, thiab cov platelets, uas yog qhov tseem ceeb rau peb txoj kev ciaj sia, thiab ntxiv rau peb cov ntshav. Txhua hom qe ntshav muaj lub luag haujlwm sib txawv rau peb lub cev. Cov pob txha nce lossis txo qhov kev tsim khoom no nyob ntawm peb lub cev xav tau.

Tam sim no, nyob rau hauv ib qho mob hu ua myelosuppression , txoj haujlwm ntawm lub Hoobkas pob txha no raug cuam tshuam rau qee qhov laj thawj. Tom qab ntawd, cov qe ntshav thiab cov platelets tsis tuaj yeem tsim tau zoo. Qhov laj thawj tseem ceeb rau qhov no yog kev kho mob chemotherapy rau mob qog noj ntshav. Txawm li cas los xij, qee hom mob qog noj ntshav thiab qee cov kab mob kuj tuaj yeem ua rau cov pob txha tsis ua haujlwm.

Cov tsos mob ntawm myelosuppression yog dab tsi?

Cov tsos mob yuav txawv ntawm ib tus neeg mus rau ib tus neeg, nyob ntawm seb koj cov pob txha puas tsim cov qe ntshav liab, cov qe ntshav dawb, lossis cov platelets.

Yog tias cov qe ntshav liab txo qis - Anemia

Cov qe ntshav liab nqa cov pa oxygen thoob plaws koj lub cev. Thaum tsis muaj txaus , ces yuav muaj ntshav tsis txaus . Cov tsos mob muaj xws li:

• Kev qaug zog
• Ua tsis taus pa / ua tsis taus pa
• kiv taub hau
• Lub plawv dhia ceev lossis tsis xwm yeem / arrhythmia
• Muaj lub suab nrov hauv pob ntseg, qee zaum nrog lub suab "thumping" thiab lub plawv dhia (Pulsatile tinnitus)
• Mob taub hau
• Qhov tawv nqaij daj ntseg
• Mob hauv siab

Neutropenia - txo qis cov qe ntshav dawb (tshwj xeeb tshaj yog neutrophils)

Cov qe ntshav dawb tawm tsam cov kab mob uas nkag mus rau hauv peb lub cev thiab tiv thaiv peb ntawm kev kis kab mob . Ib hom qe ntshav dawb hu ua neutrophils . Thaum cov pob txha tsim cov neutrophils tsawg dua vim yog myelosuppression, qhov mob no hu ua neutropenia . Neutropenia tsis muaj cov tsos mob tshwj xeeb, tab sis vim li noCov kab mob sib kis ntau zaus tuaj yeem tshwm sim, thiab thaum ntawd cov tsos mob tshwm sim.

• Kub taub hau (qee zaum hu ua febrile neutropenia )
• Kev nkees nkees
• Mob caj pas/kab mob (Mob caj pas/mob pharyngitis)
• Cov qog ntshav o
• Mob qog hauv qhov ncauj lossis nyob ib puag ncig lub qhov quav
• Mob raws plab
• Kub hnyiab thaum tso zis, zoo li koj yuav tsum tso zis sai sai, tso zis ntau zaus

Yog tias cov platelets txo qis - Thrombocytopenia

Cov ntshav platelets pab tswj kev los ntshav . Thaum cov qib no txo ​​qis, ib qho mob hu ua thrombocytopenia tshwm sim. Qhov no tuaj yeem ua rau:

• Kev los ntshav uas tsis nres ntev, txawm tias yog los ntawm qhov txhab me me los xij, lossis nyuaj rau nres qhov ntswg los ntshav.
• Cov qhov txhab tshwm sim sai dua li niaj zaus.
• Cov tsos ntawm cov pob me me liab (zoo li pob khaus) ntawm cov ceg qis - qhov no hu ua petechiae .
• Cov pob liab, ntshav, lossis xim av ntawm daim tawv nqaij - qhov no hu ua purpura .

Yog tias txhua hom qe ntshav raug txo qis - Pancytopenia

Qee zaum, tag nrho peb yam ntawm cov qe ntshav no—cov qe ntshav liab, cov qe ntshav dawb, thiab cov platelets—tuaj yeem qis tib lub sijhawm . Qhov mob no hu ua pancytopenia . Ib yam li neutropenia, qhov no tsis yog ib yam kab mob hauv nws tus kheej, tab sis nws tuaj yeem yog ib qho cim ntawm ib qho mob uas twb muaj lawm.

Vim li cas myelosuppression thiaj tshwm sim? Dab tsi yog cov ua rau?

Zoo li peb tau hais ua ntej lawm, kev siv tshuaj kho mob qog nqaij hlav yog qhov ua rau mob qog nqaij hlav ntau tshaj plaws . Txawm li cas los xij, kuj muaj lwm yam ua rau mob qog nqaij hlav thiab.

Kev kho mob chemotherapy, kev kho mob immunotherapy, thiab kev tiv thaiv kab mob myelosuppression

Muaj ntau hom tshuaj kho mob qog nqaij hlav uas ua rau muaj qhov no. Qee qhov feem ntau yog:

• Fluorouracil
• Oxaliplatin
• Irinotecan
• Capecitabine

Tsis tas li ntawd xwb, kev kho mob CAR T-cell, ib hom kev kho mob tiv thaiv kab mob , kuj tseem tuaj yeem ua rau cov pob txha tsis ua haujlwm zoo thiab txo cov qe ntshav thiab cov platelet tsim tawm.

Mob Cancer Ntshav thiab Myelosuppression

Qee cov mob qog ntshav kuj tseem tuaj yeem cuam tshuam rau kev tsim cov qe ntshav ib txwm muaj. Piv txwv li, hauv cov mob qog ntshav xws li leukemia, lymphoma, thiab myeloma , cov qe ntshav tsis zoo yuav loj hlob ntau dhau hauv cov pob txha thiab ua rau tsis muaj peev xwm tsim cov qe ntshav thiab cov ntshav platelets zoo.

Cov kab mob thiab myelosuppression

Qee cov kab mob viral kuj tseem tuaj yeem cuam tshuam cov txheej txheem tsim cov ntshav hauv cov pob txha. Xav txog tias thaum tus kab mob nkag mus rau hauv lub cev, peb lub cev tiv thaiv, uas yog cov qe ntshav dawb, tawm tsam tus kab mob. Thaum lub sijhawm sib ntaus sib tua no, cov pob txha yuav tsim cov qe ntshav liab thiab cov platelets me me. Qee qhov kev tshawb fawb qhia tias qee cov kab mob kis ncaj qha rau cov qe ntshav hauv cov pob txha, txo cov qe ntshav. Qee cov kab mob uas tau pom tias cuam tshuam nrog qhov mob myelosuppression no yog:

• Kab mob Epstein-Barr (EBV)
• Kab mob siab C
• Kab mob Parvovirus B19
• Kab mob Cytomegalovirus (CMV)
• Tus kab mob uas ua rau mob qaib ntxhw (Chickenpox / varicella zoster)
• Kab mob tiv thaiv kab mob tib neeg (HIV)
• Kab mob Dengue

Puas yog myelosuppression ua rau muaj teeb meem loj?

Yog, qee zaum qhov no tuaj yeem ua rau muaj teeb meem loj heev uas yuav ua rau tuag taus . Piv txwv li, cov qe ntshav liab poob qis tam sim ntawd (mob ntshav tsis txaus) lossis cov ntshav platelets poob qis (ntshav tsis tuaj yeem tswj tau) .

Tseem Ceeb: Yog tias koj muaj ib qho ntawm cov tsos mob no, tshwj xeeb tshaj yog tias koj tab tom kho mob qog noj ntshav, nws yog ib qho tseem ceeb heev uas yuav tsum nrhiav kev pab kho mob tam sim ntawd.

Cov kws kho mob kuaj mob no li cas kom meej?

Qhov no feem ntau yog kuaj pom los ntawm kev kuaj ntshav . Cov kev kuaj ntshav no xyuas seb koj cov pob txha puas tsim cov qe ntshav thiab cov ntshav platelets li qub.

Cov kev kuaj ntshav zoo li no ua tau:

• Kev suav cov ntshav tag nrho (CBC)
• Kev kuaj MCV (Qhov nruab nrab ntawm lub cev ntim / kev kuaj MCV)
• Kev xeem RDW (Qhov dav ntawm kev faib cov qe ntshav liab / kev xeem RDW)
• Kev suav ntawm cov reticulocyte
• Kev kuaj ntshav ntawm cov hlab ntsha sab nraud
• Kev kuaj MPV (Qhov nruab nrab ntawm cov platelet ntim / kev kuaj MPV)

Cov kev kho mob rau myelosuppression yog dab tsi?

Cov kws kho mob kho qhov no nrog cov hau kev no:

• Yog tias qhov ua rau myelosuppression yog chemotherapy, cov tshuaj chemotherapy yuav tsum tau txo lossis tsum tsis txhob noj ib ntus .
• Kev hloov ntshav kom nce cov qe ntshav liab thiab cov platelet.
• Muab cov tshuaj rau koj uas pab koj cov pob txha tsim cov qe ntshav thiab cov platelets ntau dua.

Puas tiv thaiv tau qhov teeb meem no kom tsis txhob tshwm sim?

Feem ntau cov kev mob myelosuppression tshwm sim ua ib qho kev phiv ntawm kev kho mob qog noj ntshav. Yog li ntawd, cov kws kho mob yeej ib txwm saib xyuas cov kev phiv no thaum lub sijhawm kho mob qog noj ntshav. Lawv yuav kuaj koj cov ntshav tsis tu ncua thiab hloov koj txoj kev npaj kho mob yog tias tsim nyog.

Yog tias kuv muaj myelosuppression, kuv yuav xav tau dab tsi?

Muaj coob tus neeg mob no vim lawv tau txais kev kho mob qog nqaij hlav. Yog tias muaj, koj tus kws kho mob yuav saib xyuas seb kev kho mob qog nqaij hlav cuam tshuam li cas rau koj cov pob txha. Tej zaum koj yuav tsum so ib ntus ntawm kev kho mob qog nqaij hlav kom koj cov pob txha rov tsim nws cov qe ntshav.

Kuv yuav saib xyuas kuv tus kheej li cas?

Kev mob Myelosuppression tuaj yeem ua rau koj muaj feem yuav kis tau kab mob thiab los ntshav ntau ntxiv . Koj tuaj yeem ua cov no kom txo qhov kev pheej hmoo no:

• Mus txhaj tshuaj tiv thaiv kab mob kom tiv thaiv tau cov kab mob uas feem ntau kis.
• Xyaum ua kom huv si , xws li ntxuav koj txhais tes ntau zaus thiab nyob deb ntawm cov neeg mob.
• Tiv thaiv koj tus kheej ntawm tej xwm txheej uas koj yuav raug mob lossis txiav . Piv txwv li, ceev faj thaum siv riam phom ntse.

Kuv yuav tsum nug kuv tus kws kho mob li cas?

Koj tuaj yeem nug cov lus nug rau tus kws kho mob xws li:

• Vim li cas kuv thiaj muaj tus mob myelosuppression no?
• Tus mob no cuam tshuam li cas rau kuv lub cev?
• Kuv muaj cov kev kho mob twg?
• Kev kho mob puas yuav kho tau kuv tus mob myelosuppression tag nrho?

Lus Qhia Luv: Yuav Tsum Nco Ntsoov Li Cas (Cov Lus Coj Mus Tsev)

Koj cov pob txha pob txha yog ib feem tseem ceeb ntawm koj lub cev. Cov qe ntshav liab uas nqa oxygen, cov qe ntshav dawb uas tawm tsam kev kis kab mob, cov platelets uas pab koj cov ntshav txhaws - lawv txhua tus tau tsim nyob ntawd. Myelosuppression yog thaum koj cov pob txha pob txha tsis ua haujlwm rau qee qhov laj thawj. Qhov ua rau feem ntau yog chemotherapy rau mob qog noj ntshav, tab sis nws kuj tuaj yeem tshwm sim los ntawm qee yam mob qog noj ntshav thiab cov kab mob. Tsis txhob txhawj. Cov kws kho mob yuav nrhiav qhov ua rau thiab kho nws raws li qhov tsim nyog. Qhov tseem ceeb tshaj plaws yog nrhiav kev kho mob yog tias koj muaj cov tsos mob txawv txawv thiab ua raws li lawv cov lus qhia kom zoo. Koj tsis nyob ib leeg, thiab muaj cov kws kho mob uas tuaj yeem pab koj ntawm txoj kev no.

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