Koj cov ntshav puas muaj feem yuav txhaws? (Prothrombin Gene Mutation) Cia peb kawm txog nws yooj yim xwb

Koj puas tau hnov ​​txog ib tug neeg uas cia li muaj ib ceg o thiab mob thiab tus kws kho mob hais tias lawv muaj ntshav txhaws hauv lawv ceg? Los yog ib tug neeg hluas, noj qab nyob zoo cia li muaj teeb meem ua pa thiab mob hauv siab thiab raug coj mus pw hauv tsev kho mob? Thaum peb hnov ​​tej yam zoo li no, peb yuav xav tias muaj dab tsi tshwm sim. Feem ntau, peb pom tej yam xws li kev laus thiab kev rog dhau ua qhov ua rau qhov no. Txawm li cas los xij, qee zaum qhov ua rau tuaj yeem yog ib yam dab tsi zoo li xim ntawm peb lub qhov muag, cov qauv ntawm peb cov plaub hau, lossis ib qho noob caj noob ces uas peb tau txais los ntawm peb niam peb txiv. Hnub no peb yuav tham txog ib qho mob caj ces uas ua rau muaj kev pheej hmoo ntawm cov ntshav txhaws. Qhov no hu ua Prothrombin Gene Mutation .

Hais yooj yim xwb, qhov kev hloov pauv Prothrombin Gene no yog dab tsi?

Qhov no yuav zoo li lub npe tshawb fawb, tab sis zaj dab neeg yooj yim heev. Cia peb xub saib seb cov ntshav txhaws feem ntau tshwm sim li cas hauv peb lub cev. Thaum koj raug mob me me, me ntsis ntshav ntws thiab tom qab ntawd nres tom qab ib pliag, puas yog? Qhov ntawd yog vim tias lub cev ntshav txhaws hauv peb lub cev tau ua haujlwm. Ntau hom protein pab nrog qhov no. Peb hu cov protein no ua Clotting Factors. Prothrombin yog ib qho protein zoo li no. Lwm lub npe rau qhov no yog Factor II . Feem ntau, peb lub cev tsuas yog ua cov Prothrombin uas nws xav tau. Txawm li cas los xij, hauv lub cev ntawm ib tus neeg uas muaj kev hloov pauv caj ces hu ua Prothrombin Gene Mutation, cov protein no hu ua Prothrombin raug tsim tawm ntau dua li qhov xav tau . Xav txog, yuav ua li cas yog tias ib tug neeg ntxiv tsib lossis rau diav suab thaj rau ib khob tshuaj yej es tsis txhob ob diav suab thaj? Ib yam li tshuaj yej saj qab zib dhau, thaum cov qib prothrombin nce ntxiv, peb cov ntshav dhau los ua "nplaum," lossis yooj yim dua rau kev txhaws. Qhov no ua rau muaj kev pheej hmoo ntawm cov ntshav txhaws hauv cov leeg, txawm tias tsis muaj kev raug mob. Cov ntshav txhaws no tsim nyob rau hauv cov leeg tob ntawm ob txhais ceg. Peb hu qhov mob no ua Deep Vein Thrombosis (DVT) . Qee zaum, ib daim ntshav txhaws no tuaj yeem tawg thiab thaiv cov hlab ntsha hauv lub ntsws. Qhov no yog ib qho mob txaus ntshai heev, hu ua Pulmonary Embolism (PE) .

Peb yuav tau cov noob no li cas? Homozygous thiab Heterozygous yog dab tsi?

Qhov no yooj yim to taub heev. Peb tau txais txhua yam noob caj noob ces ua ib daim qauv los ntawm peb niam thiab ib daim qauv los ntawm peb txiv. Xav txog cov noob caj noob ces no uas ua rau Prothrombin. 1. Heterozygous: Koj tau txais cov noob caj noob ces tsis zoo no los ntawm koj niam lossis txiv, uas yog, los ntawm ib tug ntawm koj niam koj txiv xwb. Tus neeg ntawd tau txais cov noob caj noob ces noj qab nyob zoo, ib txwm muaj. Muaj ntau tus neeg hauv Sri Lanka thiab thoob plaws ntiaj teb muaj tus mob no. Hauv qhov no, qhov kev pheej hmoo ntawm cov ntshav txhaws yog siab dua li tus neeg nruab nrab. Kwv yees li hais lus, ob lossis peb ntawm 1,000 tus neeg uas muaj tus mob no muaj kev pheej hmoo ntawm kev tsim cov ntshav txhaws. 2.Homozygous: Qhov no tsis tshua muaj. Qhov tshwm sim ntawm no yog tias koj tau txais cov noob caj noob ces tsis zoo los ntawm koj niam thiab koj txiv. Qhov no txhais tau tias koj tau txais ob daim qauv ntawm cov noob caj noob ces tsis zoo los ntawm ob leeg niam txiv . Hauv qhov no, qhov kev pheej hmoo ntawm cov ntshav txhaws yog ntau dua li cov neeg uas yog 'Heterozygous'.

Kuv cov menyuam puas yuav tau txais qhov no los ntawm kuv?

Qhov no yog ib qho teeb meem uas ntau tus niam txiv muaj.

• Yog koj muaj tus mob homozygous (txhais tau tias ob daim qauv ntawm cov noob caj noob ces tsis zoo), koj yuav tsum xa ib lub noob caj noob ces tsis zoo mus rau txhua tus ntawm koj cov menyuam .
• Yog koj yog heterozygous (txhais tau tias koj tsuas muaj ib lub noob caj noob ces uas tsis zoo xwb), muaj 50% feem pua ​​uas ib tug ntawm koj cov menyuam yuav tau txais lub noob caj noob ces ntawd. Nws zoo li pov ib lub npib; tej zaum koj yuav tau lossis tsis tau.

Cov tsos mob ntawm tus mob no yog dab tsi?

Nov yog qhov tseem ceeb tshaj plaws. Tsis muaj cov tsos mob uas tshwj xeeb rau qhov kev hloov pauv caj ces hu ua Prothrombin Gene Mutation. Qhov ntawd yog, txawm tias koj muaj cov noob caj ces no hauv koj lub cev, koj yuav tsis hnov ​​​​​​qhov sib txawv lossis nyuaj. Muaj ntau tus neeg tsis paub tias lawv muaj cov noob caj ces no, thiab lawv nyob tag nrho lawv lub neej yam tsis muaj cov ntshav txhaws. Yog li qhov teeb meem nyob qhov twg? Qhov teeb meem tsuas yog los ntawm cov ntshav txhaws vim yog cov noob caj ces no. Tom qab ntawd peb pom cov tsos mob ntsig txog cov ntshav txhaws ntawd.

Puas muaj lwm yam ntxiv rau cov noob caj noob ces uas ua rau muaj kev pheej hmoo ntawm cov ntshav txhaws?

Yog, yeej muaj tseeb. Peb tau hais tias tsis yog txhua tus neeg uas muaj cov noob caj noob ces no yuav muaj cov ntshav txhaws. Txawm li cas los xij, thaum muaj ib lossis ntau yam ntawm cov yam hauv qab no, qhov kev pheej hmoo tuaj yeem nce ntxiv. Nws zoo li nchuav roj av rau ntawm hluav taws.

• Haus Luam Yeeb: Haus luam yeeb ua rau cov hlab ntsha puas tsuaj thiab ua rau muaj kev pheej hmoo ntawm cov ntshav txhaws .
• Kev phais mob: Tom qab phais mob loj, koj yuav raug pw hauv txaj ob peb hnub, uas tuaj yeem ua rau cov ntshav ntws tsawg dua thiab cov ntshav txhaws.
• Kev Rog Phem : Thaum lub cev hnyav nce ntxiv, qhov kev pheej hmoo no nce ntxiv thaum muaj kev nyuaj siab ntau ntxiv rau ntawm cov leeg ntshav.
• Cev Xeeb Tub: Thaum cev xeeb tub, qhov kev pheej hmoo ntawm cov ntshav txhaws yuav nce ntxiv vim yog kev hloov pauv ntawm cov tshuaj hormones hauv lub cev thiab qhov siab ntawm cov leeg ntshav uas tshwm sim los ntawm tus menyuam uas loj hlob tuaj.
• Noj tshuaj tiv thaiv kev yug me nyuam lossis kev kho mob hormone: Qhov kev pheej hmoo yuav nce ntxiv los ntawm cov tshuaj estrogen uas muaj nyob hauv qee cov tshuaj tiv thaiv kev yug me nyuam thiab kev kho mob hormone.
• Kev laus: Qhov kev pheej hmoo ntawm cov ntshav txhaws yuav nce ntxiv nrog hnub nyoog.
• Nyob rau tib qho chaw ntev dhau lawm:
• Nyob hauv txaj pw hauv tsev kho mob tau ntau hnub.
• Hnav ib daim ntaub thaiv thaum koj tawg ceg.
• Caij dav hlau, caij tsheb npav, lossis caij lub tsheb ntau teev ib zaug.

Kuv yuav ua li cas thiaj paub tias kuv muaj tus mob no?

Qhov no tsis tuaj yeem kuaj pom los ntawm kev kuaj ntshav tas li (zoo li kev suav tag nrho cov ntshav). Yuav tsum muaj kev kuaj noob caj noob ces tshwj xeeb rau qhov no. Qhov no yog ua los ntawm kev coj cov ntshav mus kuaj. Txawm li cas los xij, tus kws kho mob tsis hais kom txhua tus ua qhov kev kuaj no. Feem ntau, tus kws kho mob xav tias qhov no thiab xaj kom kuaj hauv cov xwm txheej hauv qab no:

• Yog tias koj tau muaj ntau tshaj ib qho ntshav txhaws ua ntej.
• Yog koj muaj ntshav txhaws thaum koj tseem hluas, noj qab nyob zoo, thiab tsis muaj lwm yam kab mob.
• Yog tias ib tug txheeb ze ze hauv koj tsev neeg (niam, txiv, kwv tij neej tsa) muaj hom teeb meem ntshav txhaws no.

Yuav kho li cas?

Ntawm no peb yuav tsum ua ob lub ntsiab lus kom meej. 1. Kev kho mob rau kev hloov pauv caj ces: Raws li kev tshawb fawb kho mob tam sim no, tsis muaj txoj hauv kev los kho lossis hloov peb cov noob caj ces. Qhov no txhais tau tias Prothrombin Gene Mutation yuav nrog koj mus tas koj lub neej. 2. Kev kho mob rau cov ntshav txhaws: Txawm li cas los xij, peb tuaj yeem tswj hwm qhov kev pheej hmoo ntawm cov ntshav txhaws los ntawm cov noob caj ces no thiab kho cov ntshav txhaws uas tau tsim . Yog tias koj muaj DVT lossis PE, koj tus kws kho mob feem ntau yuav pib kho los ntawm kev muab ib hom tshuaj uas tiv thaiv cov ntshav txhaws (qhov peb feem ntau hu ua cov tshuaj thinners ntshav). Hauv cov lus kho mob, cov no hu ua anticoagulants . Hauv qee qhov xwm txheej ceev, cov tshuaj hu ua thrombolytics raug muab los ntawm kev txhaj tshuaj kom yaj thiab tshem tawm cov ntshav txhaws. Tsis tshua muaj, catheter lossis phais tuaj yeem siv los tshem tawm cov ntshav txhaws. Lub sijhawm kho mob txawv ntawm ib tus neeg mus rau ib tus neeg. Rau qee tus neeg, noj tshuaj li peb lub hlis txaus. Lwm tus yuav tsum noj cov tshuaj thinners ntshav rau tas lawv lub neej. Koj tus kws kho mob yuav txiav txim siab raws li koj tus mob thiab koj cov yam ntxwv txaus ntshai.

Qhov mob no cuam tshuam li cas rau kev xeeb tub?

Qhov no yog ib qho teeb meem tseem ceeb rau ntau tus poj niam.

• Yog tias koj muaj qhov Prothrombin Gene Mutation no thiab tau muaj ntshav txhaws yav dhau los , koj tus kws kho mob yuav pom zoo kom koj noj tshuaj thinning ntshav tsawg tsawg (tiv thaiv) txhua hnub (xws li heparin) thoob plaws koj cev xeeb tub thiab ob peb lub lis piam tom qab koj tus menyuam yug los. Cov tshuaj txhaj no tsis ua rau koj tus menyuam raug mob.
• Txawm li cas los xij, txawm tias koj muaj cov noob caj noob ces no los xij, yog tias koj yeej tsis tau muaj ntshav txhaws hauv koj lub neej , feem ntau koj tsis tas yuav kho mob thaum cev xeeb tub.

Thaum twg koj yuav tsum mus ntsib kws kho mob?

Qhov no tseem ceeb heev. Kev paub txog cov tsos mob thiab ua haujlwm thaum ntxov tuaj yeem tiv thaiv cov mob hnyav. Thaum kawg, tsis txhob ntshai yog tias koj pom tias koj muaj Prothrombin Gene Mutation. Nco ntsoov tias, feem ntau ntawm cov neeg uas muaj cov gene no tuaj yeem ua neej noj qab nyob zoo yam tsis muaj teeb meem. Qhov tseem ceeb tshaj plaws yog kom paub txog qhov no, nyob deb ntawm cov yam txaus ntshai (xws li haus luam yeeb, rog dhau), ua neej noj qab nyob zoo, thiab nrhiav kev kho mob tam sim ntawd yog tias koj muaj cov tsos mob ntawm cov ntshav txhaws. Kev Hloov Pauv ntawm Prothrombin Gene, Kev Hloov Pauv ntawm Factor II, Kev Ntshav Khi, Kev Thrombosis Ntawm Cov Hlab Ntsha, Kev Mob Pulmonary Embolism, DVT, PE, Cov Kab Mob Genetic, Kev Ua Kom Cov Ntshav Nyias, Cov Tshuaj Anticoagulants