Wernicke-Korsakoff Syndrome yog dab tsi? Cia peb tham txog nws!

Koj puas tau hnov ​​txog ib yam mob txawv txawv uas cuam tshuam rau lub hlwb thiab kev nco? Qee zaum, peb tsis paub tias thaum peb lub cev tsis muaj qee yam vitamin, tshwj xeeb tshaj yog vitamin B1 hu ua "Thiamine", peb lub hlwb tuaj yeem raug puas tsuaj loj heev. Ib qho mob hnyav heev yog Wernicke-Korsakoff Syndrome (WKS) . Qhov no yog ib yam mob uas xav tau kev kho mob ceev. Peb puas yuav tham txog qhov no yooj yim, hauv txoj kev uas koj nkag siab tau?

Wernicke-Korsakoff syndrome (WKS) yog dab tsi tiag?

Hais yooj yim xwb, qhov no yog ib yam kab mob uas cuam tshuam rau peb lub hlwb thiab kev nco. Qhov laj thawj tseem ceeb rau qhov no yog tias peb lub cev muaj kev txo qis ntawm 'Thiamine' ('Thiamine') lossis vitamin B1 . Xav txog nws, peb lub cev zoo li lub tsheb. Lub cav ntawm lub tsheb no yog lub hlwb. Lub cav xav tau roj av kom khiav. Ib yam li ntawd, cov vitamin hu ua 'Thiamine' ('Thiamine') yog qhov tseem ceeb rau peb lub hlwb thiab lub paj hlwb kom ua haujlwm. Cov vitamin no yog qhov hloov cov khoom noj uas peb noj mus ua lub zog. Yog li thaum 'Thiamine' ('Thiamine') no raug txo qis, lub hlwb tsis tau txais lub zog uas nws xav tau, thiab tom qab ntawd cov hlwb hlwb pib puas tsuaj.

Muaj ob theem tseem ceeb hauv qhov 'WKS' no:

1. Wernicke encephalopathy: Qhov no yog thawj zaug, raug mob hlwb sai sai, hnyav heev. Nws yuav tsum tau kho tam sim ntawd.

2. Korsakoff syndrome: Qhov no yog ib qho mob ntev uas cuam tshuam rau lub cim xeeb heev.

Nws tau muab lub npe rau tus kws kho mob hlwb German Carl Wernicke thiab tus kws kho mob hlwb Lavxias Sergei Korsakoff, uas yog thawj tus txheeb xyuas tus mob no.

Kev sib raug zoo ntawm 'Wernicke's encephalopathy' thiab 'Korsakoff syndrome' yog dab tsi?

Ob yam no muaj feem cuam tshuam. Yog hais kom meej, ib yam mob hu ua "Wernicke encephalopathy", yog tias tsis kho raws sijhawm, ces yuav maj mam hloov mus ua teeb meem loj heev rau kev nco qab hu ua "Korsakoff syndrome".

Feem ntau muaj peb yam tsos mob tseem ceeb ntawm Wernicke encephalopathy:

• Kev tsis meej pem: Tsis nco qab, tsis paub qhov chaw thiab lub sijhawm.
• Tsis muaj zog thiab tsis muaj peev xwm tswj tau kev txav mus los ('Ataxia'): Kev taug kev tsis ruaj khov thiab txhais ceg nyuaj rau tswj.
• Kev hloov pauv ntawm qhov muag thiab teeb meem ntawm qhov muag: Kev txav ntawm qhov muag tsis zoo li qub, xws li pom ob sab.

Ntxiv rau qhov no, qee zaum txawm tias cov leeg nqaij kuj tuaj yeem qaug zog.

Yog tias cov tsos mob no tseem muaj ntev, ces yuav ua rau lub hlwb thiab cov hlab ntsha puas tsuaj mus tas li. Qhov no yog thaum lub sijhawm uas lub cim xeeb poob loj heev thiab tsis nco qab cov cim xeeb tshiab. Qhov no hu ua "Korsakoff syndrome".

Wernicke-Korsakoff Syndrome (WKS) yog ib yam mob uas tuaj yeem zuj zus tuaj raws sijhawm thiab tuaj yeem ua rau tuag taus. Yog li ntawd, kev kho mob sai nrog thiamine yog qhov tseem ceeb. Ua li ntawd tuaj yeem pab txo cov tsos mob thiab tiv thaiv kev puas tsuaj mus tas li rau kev nco thiab lwm yam haujlwm ntawm lub hlwb.

Yog koj lossis ib tug neeg nyob ze koj muaj cov tsos mob no, koj yuav tsum mus ntsib kws kho mob tam sim ntawd lossis mus rau tsev kho mob ze tshaj plaws.

Leej twg raug kev cuam tshuam ntau tshaj plaws los ntawm qhov xwm txheej no?

Tus mob Wernicke-Korsakoff syndrome (WKS) feem ntau tshwm sim rau cov txiv neej dua li cov poj niam. Feem ntau nws tshwm sim rau cov neeg hnub nyoog ntawm 30 thiab 70 xyoo. Feem ntau cov neeg uas muaj tus mob WKS vim haus dej cawv yog cov txiv neej hnub nyoog tshaj 40 xyoo. Txawm li cas los xij, cov poj niam thiab cov hluas kuj tuaj yeem muaj tus mob no rau lwm yam laj thawj tsis yog cawv. Nws tsis tshua muaj neeg tshaj tawm hauv cov menyuam yaus.

Leej twg muaj feem yuav mob Wernicke-Korsakoff syndrome ntau dua?

Wernicke encephalopathy yog ib yam mob uas feem ntau pom muaj rau cov neeg uas haus cawv ntau dhau (kev siv cawv tsis zoo). Thaum haus cawv ntev, nws ua rau lub plab thiab lub plab zom mov puas tsuaj. Nws kuj cuam tshuam rau lub cev txoj kev nqus cov vitamins (malabsorption). Lawv hais tias kwv yees li 80% ntawm cov neeg haus cawv tsis tuaj yeem nqus lossis khaws cov thiamine txaus.

Tsis tas li ntawd xwb, cov neeg uas tsis tuaj yeem nqus tau zaub mov zoo vim muaj tej yam mob kuj tuaj yeem mob "WKS". Piv txwv li, nws tuaj yeem tshwm sim tom qab phais mob kom poob phaus ("bariatric surgery") lossis ua ib qho kev phiv ntawm "chemotherapy" rau mob qog noj ntshav.

Nov yog qee yam kev pheej hmoo ntxiv:

• Cov kab mob plab hnyuv, piv txwv li, kab mob inflammatory bowel lossis gastropathy.
• Mob qog noj ntshav (tshwj xeeb tshaj yog thaum muaj mob hnyav).
• Cov tshuaj hormones ntau dhau (thyrotoxicosis).
• Qee qhov kev hloov pauv caj ces.
• Siv cov tshuaj diuretic rau kev mob plawv tsis ua haujlwm ntev.
• Cov kab mob tsis muaj thiamine xws li HIV/AIDS.
• Kev ua tsis tau haujlwm ntawm lub raum, vim tias kev kho mob dialysis ntev yuav txo qhov peev xwm ntawm lub cev los nqus thiamine.
• Tsis muaj kev nkag mus rau cov chaw kho mob lossis cov khoom noj muaj txiaj ntsig zoo.
• ntuav thiab xeev siab ntau dhau thaum cev xeeb tub (hyperemesis gravidarum).

Dab tsi yog cov ua rau muaj 'Wernicke-Korsakoff syndrome'?

Qhov laj thawj tseem ceeb rau qhov no yog qhov tsis txaus ntawm "Thiamine". Cov vitamin tseem ceeb no yog qhov hloov cov suab thaj uas peb noj mus ua lub zog. Yog li thaum peb tsis muaj txaus "Thiamine", peb lub hlwb tsis tau txais lub zog uas nws xav tau los ua haujlwm kom zoo.

Qhov ua rau muaj thiamine tsis txaus yogHaus dej cawv ntau dhau rau lub sijhawm ntev. Cawv ua rau lub cev nyuaj rau nqus thiamine thiab khaws cia rau hauv lub siab. Cawv kuj cuam tshuam rau kev siv vitamin B1 rau lwm yam haujlwm tseem ceeb.

Tseem muaj lwm yam laj thawj thiab:

• Kev noj zaub mov tsis zoo: Tsis noj zaub mov kom sib npaug.
• Kev noj zaub mov tsis zoo: xws li anorexia thiab bulimia.
• Cov kab mob ntev.
• Kev phais: Tshwj xeeb tshaj yog kev phais xws li kev phais plab kom poob phaus.
• Kev raug mob rau lub hlwb: Tab sis qhov no tsis tshua muaj.

Cov tsos mob ntawm 'Wernicke-Korsakoff syndrome' yog dab tsi?

Qhov no tuaj yeem tshwm sim ua ntau yam tsos mob. Ib qho ntawm cov tsos mob feem ntau pom hauv cov mob hnyav yog 'kev sib cav sib ceg' . Ntawd yog, tsim cov dab neeg hauv koj lub siab los npog tej yam uas koj tsis nco qab. Xav txog, ib tug neeg tsis nco qab qee yam uas lawv tau ua nag hmo, tab sis lawv hais lus dag los npog nws, tab sis lawv tsis dag vim lawv xav tias nws tau tshwm sim tiag tiag. Lawv ntseeg zaj dab neeg.

Cov neeg uas muaj tus mob no feem ntau yuav xav tias tsis meej pem lossis tsis paub dab tsi. Qhov kev tsis meej pem no ua rau nws nyuaj rau lawv paub tias muaj qee yam tsis raug nrog lawv thiab nrhiav kev kho mob.

Cov tsos mob ntawm Wernicke encephalopathy feem ntau :

• Tsis muaj zog lossis tsis muaj peev xwm tswj tau qhov txav mus los (ataxia).
• 'Kev sib tham ua ke'.
• Kev tsis meej pem, kev chim siab.
• Nyuaj rau kev taug kev, kev taw tsis ruaj khov.
• Kev tsaug zog tsis taus.
• Lub cev kub qis tsis zoo (hypothermia).
• Teeb meem plawv: lub plawv dhia ceev (tachycardia) lossis ntshav siab qis (hypotension).
• Kev poob ntawm kev sib koom tes ntawm cov leeg nqaij (ataxia).

Cov teeb meem ntawm qhov muag kuj yog ib qho uas tshwm sim ntau:

• Kev txav ntawm lub qhov muag tsis zoo (nystagmus).
• Pom ob zaug.
• Qaug zog ntawm daim tawv muag sab saud (ptosis).
• Cov leeg nqaij ntawm qhov muag ua haujlwm tsis zoo lossis tsis muaj zog (ophthalmoplegia).

Yog tias tsis kho tus kab mob Wernicke encephalopathy, nws tuaj yeem hloov mus ua Korsakoff syndrome, uas yog ib qho teeb meem kev nco qab mus sij hawm ntev. Nws cov tsos mob muaj xws li:

• Tsis nco qab kiag li ('Amnesia') lossis tsis nco qab dab tsi tshiab.
• Kev hloov pauv tus cwj pwm: kev chim siab, kev chim sai.
• 'Kev sib tham ua ke'.
• Kev chim siab thiab kev tsis paub qhov chaw.
• Qaug zog los yog tsis muaj zog.
• Muaj kev pom kev tsis tseeb, tshwj xeeb tshaj yog thaum tsis haus cawv.
• Tsis muaj peev xwm tsom ntsoov.
• Kev taug kev tsis ruaj khov.

Muaj tej yam tsos mob uas tsis zoo dua tag nrho txawm tias kho tau zoo lawm los xij. Yog mob hnyav heev, yuav tsis nco qab ('coma'). Yog koj lossis ib tug neeg ze koj tsis nco qab, lossis yog koj muaj tej yam tsos mob ntawm 'Wernicke-Korsakoff syndrome', mus ntsib kws kho mob lossis mus rau chav kho mob ceev tam sim ntawd.

Yuav kuaj mob 'Wernicke-Korsakoff syndrome' li cas?

Kev kuaj pom tus mob 'WKS' no thaum ntxov yog qhov tseem ceeb rau kev kho mob kom zoo. Cov kws kho mob kuaj pom nws los ntawm kev kuaj lub cev, nug txog koj cov tsos mob, thiab nug txog koj keeb kwm tsev neeg. Txawm li cas los xij, nws yuav nyuaj rau kuaj pom thaum ib tus neeg tsis meej pem lossis tsis nco qab.

Tus kws kho mob yuav kuaj xyuas cov no tshwj xeeb:

• Puas muaj teeb meem siv cawv ('Kev siv cawv tsis zoo')?
• Puas muaj kev tsis noj qab haus huv?
• Puas muaj qhov tsis txaus thiamine?

Cov kev kuaj twg pab kuaj mob Wernicke-Korsakoff syndrome?

Koj tus kws kho mob yuav xaj kom kuaj ntshav los xyuas koj cov piam thaj hauv cov ntshav thiab cov thiamine. Lawv kuj tseem yuav xaj kom kuaj ntshav cawv los xyuas seb puas siv cawv thiab kuaj lub siab ua haujlwm los xyuas lub siab ua haujlwm, vim qhov no yuav qhia tau tias lub siab puas lawm.

Tej zaum yuav muaj kev ntsuam xyuas ntxiv los xyuas seb puas muaj lwm yam ua rau:

• Kev kuaj roj ntshav hauv cov hlab ntsha (ABG), uas kuaj xyuas cov pa roj carbon dioxide thiab oxygen hauv cov ntshav.
• 'Kev suav cov ntshav tiav' (`Kev suav cov ntshav tiav - CBC`).
• Kev kuaj mob toxicology.

Tej zaum koj yuav tsum tau kuaj duab xws li cov no:

• 'CT scan'.
• 'MRI' (`MRI`).
• 'Electrocardiogram' (`Electrocardiogram - EKG`).

Puas kho tau Wernicke-Korsakoff Syndrome? Yuav kho li cas?

Qhov tseeb, nws tsis yog ib yam uas kho tau tag nrho. Txawm li cas los xij, yog tias pib kho thaum ntxov, cov tsos mob yuav zoo dua thiab qee yam ntawm lawv tuaj yeem rov qab tau. Qhov no txhais tau tias tus mob "Wernicke encephalopathy" tuaj yeem tiv thaiv kom tsis txhob hnyav zuj zus mus rau "Korsakoff syndrome".

Feem ntau, kev kho mob tuaj yeem tswj lossis txhim kho cov tsos mob xws li kev tsis meej pem, teeb meem qhov muag, thiab kev poob qhov sib npaug. Koj tus kws kho mob yuav tsim ib txoj kev npaj kho mob uas haum rau koj.

Cov hauv qab no feem ntau yog ua los ua kev kho mob:

• Muab vitamin B1 los ntawm cov tshuaj ntsiav lossis cov tshuaj txhaj.
• Yog tias lub cev qhuav dej, muab cov tshuaj saline los ntawm "IV fluids".
• Kev kho cov teeb meem ntsig txog kev haus dej cawv.
• Muab kev txhawb nqa kev noj haus.
• Muab lwm cov tshuaj yog tias tsim nyog.

Koj yuav ua li cas thiaj txo tau qhov kev pheej hmoo ntawm kev muaj tus mob no?

Feem ntau, kev tsum lossis txwv kev haus dej cawv yog qhov tseem ceeb tshaj plaws uas koj ua tau los txo koj txoj kev pheej hmoo ntawm kev mob Wernicke-Korsakoff syndrome. Tsis tas li ntawd, kev noj zaub mov zoo thiab, yog tias tsim nyog, kev noj cov tshuaj thiamine hauv daim ntawv ntawm kev txhaj tshuaj lossis tshuaj ntsiav tuaj yeem pab txo koj txoj kev pheej hmoo, tshwj xeeb tshaj yog rau cov neeg uas quav dej cawv.

Yuav ua li cas thiaj paub tias tus neeg uas muaj tus kab mob Wernicke-Korsakoff syndrome yuav zoo li cas?

Yog koj lossis ib tug neeg ze koj muaj tus mob no, qhov kev kwv yees mob yuav nyob ntawm seb cov tsos mob hnyav npaum li cas thiab kuaj pom thiab kho tus mob sai npaum li cas. Kev kho mob thaum ntxov tuaj yeem thim rov qab cov tsos mob thiab tiv thaiv cov teeb meem mus sij hawm ntev. Txawm li cas los xij, yog tias tsis kho, nws tuaj yeem ua rau muaj kev tsis taus thiab txawm tias tuag.

Thaum twg koj yuav tsum nrhiav kev pab kho mob rau qhov mob no?

Yog koj lossis ib tug neeg koj paub muaj cov tsos mob ntawm Wernicke-Korsakoff syndrome, nrhiav kev kho mob tam sim ntawd. Tej zaum koj yuav tsum hu rau koj tus kws kho mob lossis mus rau chav kho mob ceev hauv tsev kho mob ze tshaj plaws kom tau txais kev kho mob ceev.

Kuv yuav saib xyuas kuv tus kheej li cas?

Kev kuaj pom tias muaj tus kab mob Wernicke-Korsakoff syndrome tsis yog ib txoj haujlwm yooj yim. Tej zaum koj yuav tsum tau mus pw hauv tsev kho mob thiab kho mob. Qhov tseem ceeb tshaj plaws yog ua raws li koj tus kws kho mob cov lus qhia, xws li txwv koj txoj kev haus dej cawv (lossis txiav nws tag nrho) thiab noj zaub mov zoo. Cov no yuav pab txhawb koj txoj kev zoo.

Ua raws li koj tus kws kho mob cov lus qhia kom zoo zoo kom tswj tau cov teeb meem thiab kho cov tsos mob. Nws yuav tsim ib txoj kev npaj kho mob rau koj tus kheej thiab pab koj rov qab noj qab haus huv.

Wernicke-Korsakoff syndrome yog ib qho mob uas tsis tshua muaj tab sis loj heev uas ua rau koj nco qab tsis tau zoo. Nws yuav tsum tau kho sai sai kom txo tau cov tsos mob thiab tiv thaiv kom tsis txhob muaj teeb meem. Thaum tus kab mob loj zuj zus, cov tsos mob ntawm lub paj hlwb, xws li kev tsis meej pem thiab kev tsis paub meej, tshwm sim. Cov tsos mob no ua rau koj lossis ib tus neeg ze koj nyuaj rau paub koj tus mob. Yog li ntawd, nws yog ib qho tseem ceeb uas yuav tsum kuaj mob thaum ntxov. Koj tus kws kho mob yuav pom zoo rau txoj kev npaj kho mob uas haum rau koj cov kev xav tau.

Tej yam tseem ceeb tshaj plaws uas yuav tsum nco ntsoov (Cov Lus Coj Mus Tsev)

Zoo, ntawm no yog cov ntsiab lus tseem ceeb uas yuav tsum nco ntsoov txog 'Wernicke-Korsakoff Syndrome' uas peb tau tham txog:

• Qhov no yog ib qho mob hnyav uas cuam tshuam rau lub hlwb thiab kev nco vim yog tsis muaj thiamine (vitamin B1).
• Qhov tseem ceeb tshaj plaws uas ua rau muaj kev pheej hmoo yog haus dej cawv ntau dhau.
• Theem pib yog Wernicke encephalopathy, uas, yog tias tsis kho, tuaj yeem ua rau muaj teeb meem nco qab mus sij hawm ntev hu ua Korsakoff syndrome.
• Kev tsis meej pem, kev nyuaj siab rau kev taug kev, teeb meem pom kev, thiab kev nco tsis zoo tej zaum yuav yog cov tsos mob tseem ceeb.
• Kev kuaj mob sai thiab kev kho mob thaum muaj xwm txheej ceev nrog thiamine yog qhov tseem ceeb.
• Txawm hais tias nws tsis tuaj yeem kho tau tag nrho los xij, kev kho mob thaum ntxov tuaj yeem tswj cov tsos mob thiab tiv thaiv kev puas tsuaj mus tas li.
• Yog koj lossis ib tus neeg koj paub muaj cov tsos mob no, nrhiav kev pab kho mob tam sim ntawd.

Vam tias cov ntaub ntawv no yuav pab tau koj. Nyob zoo!

Wernicke -Korsakoff syndrome, tsis muaj thiamine, vitamin B1, haus dej cawv, tsis nco qab, mob hlwb, thiab kab mob ntawm lub paj hlwb.