Wan nyu we fɔ no if yu gɛt kansa: Ɔltin bɔt likwid bayɔpsi!

Yu dɔn ɛva yɛri bɔt di wɔd "likwid biopsy "? Sɔntɛm yu dɔktɔ dɔn tɛl yu bɔt am, ɔ yu dɔn rid bɔt am sɔnsay. Dis na rili impɔtant, nyu tɛst we fɔ no ɛn trit kansa. So, lɛ wi tɔk bɔt am simpul ɛn klia wan tide. Natin nɔ de fɔ fred, i tan lɛk se yu padi de ɛksplen sɔntin to yu.

Wetin na dis likwid bayɔpsi? I rili simpul!

Fɔ tɔk am simpul wan, likwid bayɔpsi na tɛst we dɛn kin tek smɔl blɔd . Dis kin no if ɛni kansa tɔŋ de. Imajin se as kansa tumbu de gro, smɔl smɔl pat pan am kin brok ɛn go insay yu blɔd. Na dɛn pis dɛn de dis likwid bayɔpsi de no.

Dis tɛst de luk fɔ tu men tin dɛn:

• Circulating Tumor Cells (CTC): Dis na kansa sel dεm we de brok kכmכt frכm di tכmכro εn travul tru yu bכdi, lεk sכm sכm spay dεm.
• Circulating tumor DNA (ctDNA): Dis na pat pan DNA we de brok kכmכt frכm di kεnsar sεl dεm εn go insay di bכdi. As yu no, DNA tan lɛk buk we gɛt di jenɛtik kɔd we de kɔntrol di we aw wi sɛl dɛn de biev. So, dis pies dεm fכ ctDNA kin tεl wi bכku tin bכt kεnsar.

di prεsεns fכ dεn `(CTCs)` כ `(ctDNA)` dεm na yu bכdi na pruf fכ se kεnsar tכmכro de sכmsay na yu bכdi. Dɔn bak, bikɔs dɛn pis ya de gi `( jenɛtik infɔmeshɔn)` bak fɔ di kansa, i go ɛp yu dɔktɔ fɔ disayd us tritmɛnt we go fayn fɔ yu.

Liquid biopsy na wan nyu tɛst. I gɛt di pawa fɔ mek big difrɛns pan di wok we dɛn de du fɔ mɛn kansa. Bɔku we dɛn dɔn ɔlrɛdi de we di US Food and Drug Administration (FDA) dɔn gri fɔ yuz. Risach bɔt dis stil de go bifo.

Wetin na di difrɛns bitwin likwid bayɔpsi ɛn di rɛgyula bayɔpsi we wi no?

Yu go mɔs dɔn yɛri bɔt wan rutin biopsy. Insay de, dɔktɔ kin tek wan smɔl tisu dairekt frɔm wan kansa tumbu ɛn tɛst am na lab fɔ si if i gɛt kansa sɛl dɛn.

Bɔt we dɛn de tek wata bayɔpsi, dɛn nɔ kin tek wan pat pan di tumbu dairekt wan . bifo dat, dεn de yuz am fכ luk fכ pruf fכ kεnsar, we na di kεnsar sεl dεm ``CTCs`` כ kεnsar DNA ``ctDNA`` we wi bin tכk bכt, insay di bכdi.

Naw dɛn kin tek bayɔpsi we dɛn kin du ɔltɛm as di bɛst we fɔ no if kansa de. Dɛn kin kɔl am bak di "gold standad."

Insay likwid bayɔpsi, ivin if yu gɛt kansa, no 100% garanti nɔ de fɔ se yu go ebul fɔ no sayn dɛn fɔ am na wan blɔd sɛmpul. Bɔt if dɛn no se kansa na wata bayɔpsi, di infɔmeshɔn we i de gi bɔt di kansa sɛl dɛn rili valyu, ɛn i kin rili ɛp dɔktɔ dɛn fɔ plan di tritmɛnt.

Insay us kes dɛn dɛn kin du likwid bayɔpsi?

Yu dɔktɔ kin tɛl yu fɔ tek likwid bayɔpsi pan dɛn kayn tin ya:

• If yu gɛt mɛtastas kansa we dɔn skata to ɔda pat dɛn na yu bɔdi ɛn di tritmɛnt we yu de gɛt naw nɔ de wok lɛk aw yu bin de ɛkspɛkt. Metastatik kansa na wan kayn kansa wae kin pasmak wae dɔn skata ɔlsay na yu bɔdi. We i skata lɛk dis, i go mɔs bi se sɔm pat pan di kansa go brok ɛn go insay yu blɔd.

Dɔktɔ kin ɔda fɔ mek dɛn tek likwid bayɔpsi fɔ no tin dɛn lɛk:

• Ditarmin di prognosis: Liquid biopsies kin no di sirkulεt tכmכro sεl dεm (CTC) fכ plεnti kayn kεnsar . If di kansa sɛl dɛn nɔ bɔku na di blɔd, dat de sho se di prɔgnosis bɛtɛ. di hכy nכmba fכ di kεnsar sεl dεm de sho se di prכgnosis bכku. So, yu dɔktɔ kin du dis tɛst wan wan tɛm fɔ wach yu kɔndishɔn ɛn ajɔst yu tritmɛnt if nid de.
• Mek di tritmɛnt disizhɔn: Tritmɛnt dɛn de we de tɔch sɔm kansa sɛl dɛn nɔmɔ (targeted therapy). Dis min se if kansa sɛl gɛt sɔm mistek (muteshɔn) na in DNA, dɛn kin gi am wan patikyula mɛrɛsin we dɛn mek fɔ atak da mistek de. Wan likwid bayɔpsi kin fɛn dɛn mistek ya. Dɔn yu dɔktɔ kin gi yu tritmɛnt we spɛshal fɔ da mistek de.

Dɔn bak, yu kin gɛt likwid bayɔpsi ivin if bayɔpsi ɔltɛm nɔ pɔsibul fɔ no if yu gɛt kansa. dis na biכs fכ rεgulεr bayopsi na mכr invayv prosidכs pas likwid bayopsi. Sɔntɛm yu nɔ gɛt wɛlbɔdi fɔ mek dɛn du bayɔpsi. Ɔ, dipen pan usay di tumbu de , i kin at fɔ pul wan pat pan am we yu nɔ pwɛl di impɔtant ɔgan dɛn we de nia de.

Us likwid bayɔpsi tɛst dɛn we FDA dɔn gri fɔ?

Test dɛn we di U.S. Food and Drug Administration (FDA) dɔn gri fɔ na di wan dɛn we dɛn dɔn du risach gud gud wan ɛn pruv se dɛn nɔ gɛt wan prɔblɛm ɛn dɛn kɔrɛkt. Bɔku likwid bayɔpsi tɛst dɛn stil de na di risach stej. Fo men tɛst dɛn de we di FDA dɔn gri fɔ naw:

1. Sεl Sכch® Sεl Sεl (CTC) Tεst: Dis de tεst fכ CTC dεm. Brest, prɔstatDɛn kin yuse dis fɔ gɛt aidia bɔt di fiuja stetmɛnt fɔ pipul dɛm wae gɛt kansa wae dɔn spre to di kɔlon ɔr rεktum. If na smɔl CTC dɛn de na di blɔd, dat na gud sayn. If plenti CTC de, dat na likl unfavorable.

2. cobas® EGFR Mכtayshכn Tεst v2: Dis de tεst fכ ctDNA. i de dεtekt wan mכtεshכn na di jin we dεn kכl EGFR, we kכmכn pasmak pan nכn sכm sכl lכng kεnsar (NSCLC). Dis infɔmeshɔn kin ɛp yu dɔktɔ fɔ disayd us tritmɛnt we bɛtɛ fɔ tɔch da muteshon de.

3. Guardant360® CDx: Dis de luk bak fכ ctDNA. Dɛn kin yuz am fɔ no di prɔblɛm dɛn we de na di jɛnɛtiks we kin apin na di kansa sɛl dɛn. Dis kin ɛp di dɔktɔ fɔ pik di tritmɛnt we go wok fayn pas ɔl.

4. FoundationOne® Liquid CDx: Dis de luk bak fכ ctDNA. Dis kin ɛp fɔ no di jenɛtik difrɛns (muteshɔn) na difrɛn kayn kansa. Dis kin ɛp di dɔktɔ fɔ disayd us tritmɛnt we fayn pas ɔl.

Aw dɛn kin du likwid bayɔpsi? Yu tink se i de mek pɔsin fil bad?

Likwid bayɔpsi na wan rili simpul blɔd tɛst . Jɔs lɛk aw yu go gi blɔd sɛmpul fɔ mek dɛn du blɔd tɛst ɔltɛm. Dɔktɔ ɔ nɔs go tek blɔd na yu an ɛn sɛn am na lɛb fɔ mek dɛn tɛst am.

Na di lab, wan mashin kin separet yu blɔd insay di sɛl pat dɛn (solid pat) ɛn di plasma (likwid pat). Dɔn, wan dɔktɔ we de mɛn sik dɛn, we na spɛshal pɔsin we dɛn tren fɔ analayz di wata ɛn tisu sɛmpul dɛn, kin luk fɔ sayn dɛn fɔ sik na di plasma pat, we dɛn kɔl CTC ɔ ctDNA.

Yu tink se dis kin mek pɔsin fil bad? Nɔ, we yu tek wata bayɔpsi, i kin tan lɛk se yu de gi blɔd. We dɛn put di nidul insay yu an, yu kin fil smɔl smɔl, lɛk se ant bit yu. Bɔt da diskɔmfɔt de kin go kwik kwik wan.

Wan bɛnifit we likwid bayɔpsi gɛt na dat i nɔ kin izi fɔ du ɛn i nɔ kin mek pɔsin fil pen pas we dɛn kin tek bayɔpsi ɔltɛm.

Wetin di rizɔlt fɔ dis tɛst se?

di tεst rizulεt de tεl yu if yu blכd sεmpl gεt εni wan pan di `(CTCs)` כ `(ctDNA)` (`positiv`) כ nכ (`negative`) .

• if di rizulεt na ``positiv`` , i min se di tin dεm we dεn mεnshכn de insay di bכdi. Dɔn, dɛn tɛst ya kin ɛp bak fɔ no us kayn kansa yu gɛt. in patikyula, tεst dεm we de luk fכ ``(ctDNA)`` kin כlso no di kכmכn jεnεtik dεfekt dεm we de asai fכ sכm kayn kεnsar.

Aw lɔng i kin tek fɔ gɛt di rizɔlt? Aw di likwid bayɔpsi kɔrɛkt?

Bɔku tɛm fɔ gɛt di tɛst rizɔlt insay tu to tri wiks .

Naw lɛ wi luk aw dis kɔrɛkt. Liquid biopsy test dɛm we di FDA dɔn gri fɔ, wetin dɛn mek am fɔ, ɛn du ɛksaktɔli da wok de.

• De dɔktɔ kin gɛt aydia bɔt aw yu sik go kam tumara bambay ɛn wach aw yu sik de kam tru `(CTC)` tɛst.
• biכs ``(ctDNA)`` tεst kin no di jεnεtik dεfekt dεm na di DNA fכ di kεnsar sεl dεm, dεn de εp fכ mek tritmεnt disizhכn.

Bɔt dɛn nɔ kin abop pan likwid bayɔpsi ɔltɛm fɔ no if pɔsin gɛt kansa wit 100% shɔ . wan standad bayopsi nid fכ kכnfכm se kεnsar de.

Naw, likwid bayɔpsi tɛst na eria we dɛn de du aktif risach ɛn divɛlɔpmɛnt. Di ebul fɔ no ɛn wach kansa wit simpul blɔd tɛst na big tin. Risach de go bifo fɔ mek likwid bayɔpsi tɛst dɛn we go ebul fɔ no kansa bifo i ivin kam. Bɔt dɛn nid fɔ du mɔ risach fɔ ɔndastand di ful pɔtnɛshɛl fɔ likwid bayɔpsi. Ɔlrɛdi, dɛn de ɛp fɔ no sɔm kayn kansa ɛn disayd fɔ trit am pan patikyula kes dɛm. tumara bambay, i go mɔs bi se dɛn go gɛt mɔ bɛnifit.

Fɔ dɔn, tin dɛn we wi nid fɔ mɛmba

Okay, so wi don tok plenti boht likwid biopsy. Na sɔm tin dɛn we yu fɔ mɛmba:

• Liquid biopsy na nyu tɛst we de luk fɔ kansa mak dɛn na di blɔd .
• dis kin dεtekt `(CTCs)` (kansa sεl dεm) εn `(ctDNA)` (kansa DNA).
• Nɔr big diskɔmfɔt ɔ pen nɔr de lɛk bayɔpsi ɔltɛm.
• Dis kin ɛp fɔ gɛt aidia bɔt aw di kansa go bi tumara bambay ɛn fɔ disayd aw fɔ trit am .
• Sɔm tɛst dɛn we FDA dɔn gri fɔ dɔn ɔlrɛdi de.
• Bɔt fɔ mek dɛn no if pɔsin gɛt kansa, i kin nid fɔ du bayɔpsi ɔltɛm .
• Dis na teknɔlɔji we stil de divɛlɔp ɛn i go rili yusful tumara bambay.

Di tin we impɔtant pas ɔl na, if yu gɛt ɛni kwɛstyɔn ɔ wɔri bɔt dis, fɔ tru, tɔk to yu dɔktɔ. I kin ɛksplen ɔltin to yu di we we go bɛtɛ fɔ yu.

A op se dis infɔmeshɔn go yusful to yu! Stay wit wɛlbɔdi!

` Liquid Bayopsi, Kansa, Kansa Ditekshɔn, ctDNA, CTC, Blɔd Tɛst, Kansa Tritmɛnt