Yu no bɔt Stem Sɛl Tɛrapi fɔ Ankylosing Spondylitis?

If yu gɛt Ankylosing Spondylitis, ɔ AS, yu no aw i at fɔ gɛt bak ɛn jɔyn pen ɛn stiff. Pan ɔl we bɔku pipul dɛn kin fil fayn wit di mɛrɛsin dɛn we dɛn de tek naw, nɔto ɔlman kin ebul fɔ tek dɛn. Sɔm pipul dɛn kin gɛt sɔm bad bad tin dɛn. Na dat mek sayɛnsman dɛn de tray ɔltɛm fɔ fɛn bɛtɛ tritmɛnt fɔ dis sik. Wan pan dɛn tritmɛnt ya we gɛt prɔmis na stem sɛl tɛrapi, ɔ as wi ɔl no am, ‘Stem Sɛl Tɛrapi.’ Lɛ wi tɔk bɔt am insay simpul wɔd dɛn tide.

Wetin na dɛn stem sɛl ya?

Fɔ tɔk am simpul wan, ɔl di ɔda sɛl dɛn na wi bɔdi lɛk blɔd sɛl dɛn, mɔsul sɛl dɛn, ɛn skin sɛl dɛn, na dɛn ‘mama sɛl dɛn ya’ we dɛn kɔl stem sɛl dɛn kin mek fɔs. Tink bɔt dɛn lɛk blank pepa. Dɛn sɛl dɛn ya kin mek kɔpi fɔ dɛnsɛf. Dɛn kin bi bak ɛni kayn sɛl we di bɔdi nid. Fɔ ɛgzampul, dɛn sɛl ya gɛt di wɔndaful pawa fɔ mek di tisu ɛn ɔgan dɛn we dɔn pwɛl na di bɔdi.

So, insay dis stεm sεl tεrapi, dεn kin put hεlty stεm sεl dεm insay di bכdi εn εp di bכdi fכ hεl insεf frכm wan sik. Tu men kayn we dɛn de fɔ mɛn dɛn sɛl ya:

• Autologous: Dɛn kin yuz sɛl dɛn we dɛn tek frɔm di pɔsin we de gɛt di tritmɛnt.
• Allogenic: I de yuz sɛl dɛn we dɛn gɛt frɔm ɔda pɔsin we gɛt wɛlbɔdi (mama ɛn papa, brɔda ɛn sista, ɔ pɔsin we nɔ gɛt fambul fɔ gi am).

Dis tritmɛnt fɔ AS rili wok?

Wan pɔynt de we wi nid fɔ rili tek tɛm bɔt na ya. Pan ɔl we stem sɛl tɛrapi gɛt prɔmis fɔ mɛn bɔku sik dɛn tumara bambay, dɛn nɔ ɔfishal wan gri fɔ am yet as tritmɛnt fɔ Ankylosing Spondylitis (AS). Dɛn nɔ dɔn gri fɔ am yet fɔ sik dɛn lɛk at at sik ɛn pen we nɔ de dɔn.

Bɔt, wi nɔ fɔ giv ɔp op ɔltogɛda. I pɔsibul fɔ mek dis kin bi tritmɛnt we dɛn dɔn gri fɔ tumara bambay. Sayɛnsman dɛn stil de du risach bɔt difrɛn kayn stem sɛl dɛn.

di mεsenchymal stεm sεl dεm (MSC) .

Dis na spɛshal kayn sɛl we de ɛp fɔ mek tin dɛn lɛk bon, katilej, mɔsul, ɛn fat we de na wi bɔdi fayn. Dɛn kin ɛp bak fɔ rigul di imyun sistɛm ɛn kɔntrol di inflamɛns na di bɔdi.

Wan tiori bitwin sayɛnsman dɛm na dat, sɔmtin kin de we nɔr de wit dɛn MSC ya frɔm AS pasɛnt dɛm. So, dεn biliv se fכ injεkt MSC dεm frכm hεlty pכsin kin kכrekt di imyun sistεm imbalans we de כndalayn AS.

Sɔm rili smɔl stɔdi dɛn dɔn sho sɔm fayn fayn tin dɛn we go apin:

• Insay wan stɔdi, dɛn gi di MSCs sɛl dɛn we dɛn gɛt frɔm di ɔmbilikal kɔd blɔd to fayv AS pasɛnt dɛn, ɛn dɛn bin ridyus dɛn pen ɛn di simptom dɛn.
• Insay wan ɔda stɔdi, we dɛn gi 31 AS pasɛnt dɛn MSCs sɛl dɛn we kɔmɔt frɔm bon mɛrɔ, 7 pan 10 bin gɛt sɔm rilif. Bɔt dɛn rizɔlt ya bin de fɔ shɔt tɛm nɔmɔ we na lɛk 7 wiks.
• rεsכch we dεn yuz mays dεn sho se MSC dεm kin chenj di sεl dεm we de mek inflameshn.

Bɔt bak, mɛmba se dɛn stɔdi ya na rili smɔl smɔl stɔdi dɛn. Wi nɔ go ebul fɔ tɔk fayn fayn wan te wi si di tin dɛn we dɔn kɔmɔt frɔm big stɔdi dɛn.

Aw dis tritmɛnt sef?

I gɛt gud ɛn bad tin dɛn fɔ ɛni mɛrɛsin, bɔt wan stem sɛl tritmɛnt we ɔfishal gri fɔ, dɛn kin du sɔm strɔng tɛst dɛn bifo dɛn mek am fɔ ɔlman.

Insay klinik trayal fɔ AS, dɛn dɔn sho se MSC tritmɛnt na jɔs sef ɛn i nɔ de mek ɛni siriɔs sayd ɛfɛkt. Bɔt dis tritmɛnt nɔ kin wok fɔ ɔlman. Sɔm pipul dɛn nɔ kin gɛt ɛni impɔtant tin fɔ du wit dɛn sik, bɔt dɛn nɔr dɔn ripɔt bɔt dis sik kin wɔs.

Di sayd ɛfɛkt dɛm we dis tritmɛnt kin gɛt na di wan dɛm we kin kam wit di infushɔn prɔses.

• Fiva we kin apin fɔ shɔt tɛm afta dɛn dɔn trit am.
• Pen na di say we dɛn put di nidul.

Pipul dɛm wae gɛt stem sɛl tɛrapi fɔ sik dɛm lɛk kansa kin gɛt kemotɛrapi ɔ redyushɔn bak, we kin mek dɛn gɛt mɔ blɔd ɛn gɛt infɛkshɔn. So, i impɔtant fɔ tɔk bɔt dis wit yu dɔktɔ ɛn mek yu no klia wan bɔt ɔl di prɔblɛm dɛn we kin apin .

Kɔst ɛn Klinik Trial dɛn

Dis tritmɛnt kin tek bɔku bɔku mɔni. Ɛn bikɔs i stil na ɛkspirimɛnt tritmɛnt fɔ AS, yu wɛlbɔdi inshɔrans nɔ go kɔba am.

Wan tin we yu kin du fɔ dis na fɔ jɔyn wan klinik trial . Dis na stɔdi dɛn we de tɛst if nyu mɛrɛsin ɔ tritmɛnt dɛn de wok ɛn sef bifo dɛn mek am fɔ di pipul dɛn.

Aw fɔ jɔyn wan klinik trial?

Yu kin aks yu dɔktɔ bɔt wan klinik trial we go fayn fɔ yu. I kin no bɔt institiushɔn dɛn we gɛt gud nem we de wok na dis eria.

Bifo yu tek pat pan dis kayn risach, tek tɛm tink bɔt ɔl di gud ɛn bad tin dɛn. Dɛn kwɛstyɔn ya go ɛp yu fɔ du dat:

• Wetin na di men rizin fɔ dis risach?
• Wetin a nid fɔ du fɔ tek pat?
• A go gɛt fɔ spɛn ɛni mɔni?
• Aw lɔng dis risach go las?
• Dis go ambɔg ɔda tritmɛnt dɛn we a de tek naw?
• Wetin kin apin if sɔntin nɔ apin?