Wetin na dɛn prostaglandin ya? Wetin mek dɛn rili impɔtant to wi bɔdi?

Tide wi go tɔk bɔt wan smɔl kemikal we de mek insay wi bɔdi ɛn we de wok rili strenj wan. Dɛn kɔl dis prɔstagladin dɛn . Sɔntɛm yu nɔ bin dɔn yɛri dis nem bifo. Bɔt, yu no aw dɛn smɔl smɔl tin ya kin afɛkt wi bɔdi in wɛlbɔdi ɛn di tin dɛn we wi kin du ɛvride! So, tide wi go tɔk bɔt dɛn prostaglandin ya insay wan simpul, izi fɔ ɔndastand.

Wetin rili na di prostaglandin dɛn?

Fɔ tɔk am simpul wan, prostaglandin na wan grup we gɛt lipid dɛn we kin kɔmɔt na wi bɔdi we di tisu dɛn dɔn pwɛl ɔ we infɛkshɔn de, ɛn dɛn kin wok lɛk ɔmon dɛn. Bɔku difrɛn kayn dɛn de, ɛn dɛn kin ɛp fɔ kɔntrol bɔku impɔtant tin dɛn we de apin na wi bɔdi.

Tink bɔt dɛn lɛk smɔl mɛsenja dɛn we de insay wi bɔdi. We prɔblɛm de sɔmsay, dɛn mɛsenja ya kin fɔm rayt de ɛn gi signal to ɔda sɛl dɛn fɔ du wetin dɛn nid.

Dis na ɔmon bak?

Yu kin de tink se, "So dis na wan kayn ɔmon?" fכ tru, prostaglandin na wan kayn lipid we gεt prכpati dεm we lεk כmon. Lipid na fεt asid כ di tin dεm we de kכmכt frכm dεm. wi bכdi de mek dεn prostaglandin dεm ya frכm wan fεt asid we dεn kכl arachidonic acid.

Dɛn kɔl dɛn tin ya ɔmon bikɔs dɛn de kɔdinɛt difrɛn tin dɛn we wi bɔdi de du ɛn tɛl di bɔdi wetin fɔ du ɛn ustɛm fɔ du am.

Bɔt, dɛn tin ya difrɛn frɔm rial ɔmon dɛn. Aw yu no? di prostaglandin dεm nכ de wok lεk di כmon dεm we di gland dεm we de na wi εndokrin sistεm de mek εn we de kכmכt na di bכdi. Bifo dat, na wi tisu dɛn de mek dɛn na di say we di damej ɔ di infɛkshɔn, usay di akshɔn de apin. Na dat mek dɛn spɛshal.

Us savis prostaglandin dɛn de gi wi bɔdi?

infakt, difrεn kayn prostaglandin dεm de, εn difrεn risεptor dεm de bak we de ansa dεm. Dis min se wi kin si di tin dɛn we dɛn kin du na ɔlmost ɔl pat na wi bɔdi. Di ifekt we wan prostaglandin gɛt de dipen pan sɔm tin dɛn:

• Di ɔgan ɔ tisu we i kɔnɛkt to.
• Di riseptɔ we i de tay to.
• Wan prכsεs כ fysiolojikal kכndishכn we de apin na di bכdi.

Lɛ wi luk sɔm pan di men wok dɛn we dɛn prostaglandin ya de du:

• I kin ɛp fɔ bigin fɔ mek blɔd klɔt na di say we pɔsin wund, ɔ i kin ivin stɔp am.
• Di blɔd vesel dɛn kin big (vasodilation) ɔ smɔl (vasoconstriction), we kin afɛkt di we aw di blɔd de flɔ .
• I de ɛp di we aw pɔsin de wɛl .
• Swɛl (Dis na wetin kin mek yu swel ɛn rɛd we yu gɛt wund .
• i de εp fכ stat fכ bכn we uman bεlε (labor induction) .
• we uman de mεnstral, i de mek di uterus kכntrakt εn i de εp fכ shed di uterin layn (εndometrium).
• I gɛt fɔ du wit di ovuleshɔn .
• I kin mek pɔsin gɛt fiva .
• Fɔ kɔntrol aw yu de fil pen .
• I de ɛp fɔ ridyus di prɛshɔn we de insay di yay.
• I de ridyus di asid we de kɔmɔt na di bɛlɛ.
• di smol smol mכsul dεm na wi gεstrointestinal trakt de kכntrakt כ rilaks.
• I de kɔntrol di wok we sɔm ɔda ɔmon dɛn de du.

di tin we impɔtant pas ɔl na dat di prostaglandin dɛn gɛt rili shɔt af layf. Dat min se na fɔ shɔt tɛm nɔmɔ dɛn kin wok. So, dεn kin כnli afekt di sεl dεm we de nia de. Difrɛn tisu dɛn na wi bɔdi kin mek dɛn.

Lɛ wi tek ɛgzampul frɔm ɛvride layf?

Imajin se yu kɔt yu finga. Ivin smɔl wund kin du bɔku wok. Na dis na aw di prostaglandin dɛn kin ɛp:

1. I de stɔp blɔd: Fɔs, di prɔstaglandin dɛn de kɔmɔt na di tisu dɛn we de na di say we dɛn kɔt. dis dεm de tεl di pletlet dεm na di bכdi fכ "kכmכt tכgeda kwik kwik wan εn kכloz di wund, stכp di bכdi we de bכn." Dɔn wan blɔd klɔt kin fɔm de.

2. I de kɔntrol di blɔd vesel dɛm: Dɔn, ɔda kayn prostaglandin de kɔmɔt na di tisu dɛm we de na di say we di injuri de ɛn mek di blɔd vesel dɛn kɔntrakt smɔl. Dɛn kɔl dis vasoconstriction . Dis kin mek di blɔd nɔ bɔku mɔ ɛn mɔ.

3. Inflammation (swelling): Dɔn, di prostaglandin dɛn kin kɔmɔt, we kin mek di inflamɛns. Dɛn tin ya kin mek wata kɔmɔt na di blɔd vesel dɛn go insay di tisu dɛn, ɛn dis kin mek di wund swel, rɛd, ɛn fil wam. Nɔ wɔri, dis swɛlin na fɔ di gud. Dis na bikɔs i de stɔp tin dɛn lɛk jem dɛn we bin fɔ dɔn go insay di wund fɔ go na ɔda pat dɛn na di bɔdi. Dɛn inflammatory prostaglandin ya kin du ɔda tin bak. Dat min se dɛn kin briŋ wayt blɔd sɛl dɛn we dɛn kɔl fagocytes to di wund. dis sεl dεm na dεn wan dεm we de ‘it’ jεm εn day sεl dεm εn klin di wund.

4. Dɛn kin pul di blɔd we i dɔn wɛl: Fɔ dɔn, we di wund dɔn wɛl, di prɔstaglandin dɛn kin kam bak insay ɛn sɔlv di blɔd we dɔn klɔt ɛn pul am. Na bikɔs i nɔ nid fɔ de de igen.

Yu dɔn si aw bɔku prostaglandin dɛn de wok ivin pan smɔl wund?

So, yu tink se prostaglandin dɛn gud ɔ bad?

Dis na kwɛstyɔn we rili impɔtant. כnda nכmal tin dεm, di prostaglandin dεm naI impɔtant, natin nɔ de fɔ wi bɔdi. Dɛn kin ple big pat fɔ kɔntrol di natura bɔdi prɔses dɛm lɛk pen ɛn inflamɛns. di nכmal inflammatory prכsεs na rili wan we we wi bכdi de yuz fכ protεkt sεf frכm mכr damej.

Bɔt sɔntɛnde, di prɔstaglandin dɛn we de na wi bɔdi kin bɔku we wi nɔ nid. Na da tɛm de di prɔblɛm dɛn kin bigin. We dat apin, i kin gɛt inflamɛns we nɔ de dɔn ɛn pen we pɔsin nɔ go ebul fɔ bia. If dɛn kayn tin ya, di prɔstaglandin dɛn we pasmak kin mek pɔsin gɛt sik dɛn we nɔ de mɛn ɛn i kin mek i gɛt sayn dɛn we nɔ kin fayn.

fכ egzampl, pan כl we di prostaglandin dεm implεnt fכ mεnstral, if i inkrεs tumɔs, i kin mek i fil pen εn ebi ebi blɔd (menorrhagia) .

di rol we di prostaglandin dεm de ple we uman bεlε

we uman bεlε εn bכn pikin, di sεl dεm na di uterus de mek prostaglandin dεm. dis dεm de εp fכ dilayt di sεviks εn mek di uterin kכntrikshכn. dis kכntrikshכn dεm de εp fכ push di pikin dכn di bכn kanal.

Dɔn bak, sɔntɛnde dɔktɔ dɛn kin yuz sintetik prɔstagladin fɔ mek dɛn bɔn pikin if dɛn se dɛn fɔ bigin bɔn pikin bifo i bigin fɔ bɔn pikin.

Aw dɛn kin yuz di prɔstaglandin dɛn fɔ mek mɛrɛsin?

Dɔktɔ dɛn kin yuz sɔm kayn sintetik prɔstaglandin fɔ trit difrɛn tin dɛn ɛn difrɛn tin dɛn we kin apin. Lɛ wi luk sɔm ɛgzampul dɛn.

• Travoprost: Dɛn kin yuz am fɔ trit glaukoma ɛn ocular hypertension.
• dinoprostone: I de εp fכ dilayt di sεviks insay mama dεm we de nia di εnd fכ dεn bεlε εn bigin fכ bכn.
• Alprostadil: Dis de pan wan klas ɔf drɔgs we dɛn kɔl vasodilators. Dɛn kin mek blɔd flɔ mɔ. dεn de εp fכ trit sכm hat kכndyushכn dεm na bεlε pikin dεm (e.g., saynotik at sik) εn εrectile dysfunction (ED) na man dεm.
• Misoprostol: Sɔntɛnde, dɛn kin gi dis mɛrɛsin na di rɛktal fɔ stɔp di blɔd we de kɔmɔt pasmak afta dɛn bɔn pikin (pɔstpartum hemorrhage).
• Iloprost: Dɛn kin yuz am fɔ trit pulmonary hypertension ɛn wan kɔndishɔn we dɛn kɔl CREST syndrome.

Bikɔs tumɔs prostaglandin kin mek pɔsin fil pen ɛn inflamɛns we nɔ nid, dɔktɔ dɛn kin yuz drɔgs bak we de ridyus di ifɛkt dɛn we prostaglandin gɛt, ɔ we de stɔp dɛn. Di mɛrɛsin dɛn we dɛn kin yuz mɔ fɔ blok di prɔstaglandin dɛn na:Nɔn-stɛroyd Anti-inflammatory Drugs (NSAID dɛn). Dɛn kin kɔl dɛn tin ya mɛrɛsin fɔ mek pɔsin fil pen. εgzampl dεm na aspirin (e.g. Excedrin®), ibuprofen (e.g. Advil®, Motrin®), εn naproxen sכdiכm (e.g. Aleve®).

Us prɔblɛm dɛn we di prostaglandin kin kam wit?

Sɔntɛnde wi bɔdi kin mek tumɔs prostaglandin, ɔ nɔ kin mek dɛn inof. Dis kin mek yu gɛt sɔm kayn wɛlbɔdi prɔblɛm ɛn sɔm sayn dɛn.

Di prɔstaglandin dɛn we pasmak

If di amount of prostaglandins na wi bɔdi go ɔp we wi nɔ nid, i kin mek di bɔdi inflamɛns we nɔ nid ɛn we nɔ de ɛp. Na sɔm pan de wɛl bɔdi prɔblɛm dɛm wae kin kam:

• Pen we nɔ de dɔn.
• Inkris sɛnsitiviti to pen.
• Menstrueshɔn we de mek yu fil pen ɔ we yu de fil pen (dysmenorrhea).
• Ebi ebi blɔd we de kɔmɔt na yu mɔnt.
• Sɔm kayn kansa dɛn.

Nɔ gɛt di prostaglandin dɛn

Sɔntɛnde, di bɔdi nɔ kin mek inof prostaglandin fɔ mɛn wund ɔ fɔ bigin fɔ bɔn pikin afta we i gɛt ful bɛlɛ. ivin if dεn kכndyushכn ya nכ gεt kכndyushכn dεm we de te, sεntetik prostaglandin dεm kin εp. Dɔktɔ dɛn kin yuz sintetik prostaglandin fɔ mɛn bɛlɛ ɔlsa ɛn glaukoma. Dɛn kin ɛp bak fɔ bigin fɔ bɔn pikin.

Ustɛm yu fɔ go to dɔktɔ bɔt prɔblɛm dɛn we gɛt fɔ du wit prɔstaglandin?

If yu gɛt pen we nɔ de dɔn ɛn/ɔ inflamɛns we nɔ de dɔn , mek shɔ se yu go to dɔktɔ. Pan ɔl we bɔku tin kin de we kin mek yu gɛt dɛn sik ya, wan tin we kin mek yu gɛt dis sik na di we aw di prɔstaglandin dɛn kin du na yu bɔdi.

Dismɛnɔria na wan kɔmɔn sik we gɛt fɔ du wit prostaglandin ɛn na wan mɛrɛsin we nid fɔ go to dɔktɔ. If yu gɛt pen we yu de fil we yu de tek pen kil (NSAID), tɔk to yu dɔktɔ. Sɔntɛnde, di tɛm we pɔsin kin fil pen kin kam bikɔs ɔf wan sik we de ɔnda di mɛrɛsin, lɛk ɛndometriɔsis ɔ uterine fibroids .

Prostaglandin na tin we de apin na di wɔl, pawaful tin dɛn we de afɛkt bɔku pat dɛn na wi bɔdi. Pan ɔl we dɛn impɔtant fɔ di bɔdi prɔses lɛk fɔ wɛl, tumɔs prostaglandin kin mek yu gɛt pen we nɔ de dɔn, inflamɛns, ɛn yu nɔ gɛt bɛtɛ kwaliti fɔ liv. If yu gɛt pen ɔ inflamɛns ɔltɛm, go to dɔktɔ fɔ fɛn di tin we mek yu de fil ɛn gɛt di rayt tritmɛnt plan.

Mɛsej we dɛn kin kɛr go na os

Okay, so wi don tok plenti boht prostaglandin tide, no so? Di tin we impɔtant pas ɔl fɔ mɛmba na dat dɛn tin ya tan lɛk smɔl smɔl kemikal mɛsenja dɛn we dɛn kin mek na wi bɔdi ɛn we kin du wan rili impɔtant wok.

• Dɛn tin ya kin ɛp fɔ du bɔku tin, lɛk fɔ mɛn wund, fɔ stɔp blɔd, fɔ kɔntrol di inflamɛns, fɔ ɛp fɔ bɔn pikin, ɛn fɔ mek uman gɛt mɔnt.
• Dɔn bak, if dɛn tin ya bɔku pasmak, prɔblɛm dɛn lɛk pen ɛn swel we de kɔntinyu fɔ de kin apin.
• If yu gɛt pen ɔltɛm, yu de swel, ɔ yu de gɛt siriɔs kramp we yu de gɛt we yu de si yu mɔnt, i impɔtant fɔ go to dɔktɔ we yu nɔ fɔ pe atɛnshɔn to dɛn, bikɔs i kin bi bikɔs dɛn prostaglandin ya nɔ balans.

So, if wi no bɔt dɛn wɔndaful tin ya we de apin insay wi bɔdi, dat go ɛp wi fɔ gɛt wɛlbɔdi.

` Prostaglandin, ɔmon, pen, swɛlin, inflamɛns, mɔnt, bɛlɛ