Akromegali: Yu an ɛn yu fes big pasmak? Mek wi tok!

Yu dɔn ɛva notis se di shep fɔ yu an, yu fut, ɔ yu fes de chenj? Sɔntɛm ring we yu kin wɛr kin fil tayt, ɔ yu sus saiz dɔn chenj? Dɛn tin ya nɔr kin jɔs bi random tin, dɛn kin bi sayn fɔ wan sik wae nɔr kin bɔrku bɔt wae kin siriɔs wae dɛn kɔl akromegaly . Nɔ wɔri, wi go tɔk bɔt dis ditayli ɛn simpul wan tide.

Wetin na Akromegali? Fɔ tɔk am simpul wan...

Acromegaly na wan sik wae de kam wae yu gɛt bɔrku kemikal wae dɛn kɔl Growth Hormone (GH) na yu bɔdi. Nɔmal wan, dis ɔmon we de mek pɔsin gro (GH) na di pituitary gland , we na wan gland we saiz lɛk pis we de na di say we wi bren de mek. כltu, insay akromegali, dis כmon de prodyuz pasmak biכs fכ wan tכmכro na di pituitary gland כ כdasay na di bכdi.

Yu no se di pituitary gland na smɔl bɔt rili impɔtant gland. I de pul et ɔmon dɛn, wan pan dɛn na growth ɔmon (GH).

Wetin na growth hormone (GH) fɔ wi?

Growth Hormone, we dɛn kin kɔl bak Human Growth Hormone (hGH) ɔ Somatotropin , na natura l ɔmon. I impɔtant fɔ mek difrɛn pat dɛn na wi bɔdi gro ɛn fɔ mek wi ayt we wi smɔl. כltu, as wi de ol, afta di epiphyses fכ wi bon dεm dכn klos, wi bכdi stil nid dis GH. Yu no wetin mek? I de ɛp fɔ mek wi bon dɛn, di katilej, ɛn di ɔgan dɛn we de insay wi kɔntinyu fɔ gɛt wɛlbɔdi, ɛn i de ɛp fɔ mek di bɔdi wok fayn, mɔ fɔ mek di glukɔs na wi blɔd de di rayt lɛvɛl.

So, if di bכdi in gכt כmon (GH) inkrεs tu mכch afta i big, prכblεm lεk di bon dεm we de fכm, di כgan dεm we de big, εn di bכdi shuga lεvεl (hyperglycemia) kin apin.

Wetin na di difrɛns bitwin Acromegaly ɛn Gigantism?

Dɛn tu tin ya kin apin bikɔs di ɔmon we de gro (GH) de bɔku. Bɔt di difrɛns de pan udat di sik de afɛkt. Big pipul dɛn kin gɛt akromegali. Pikin dɛn kin gɛt big big bɔdi .

if di growth כmon (GH) lεvεl dεm inkrεs pan pikin dεm bifo di growth plet dεm na dεn bon dεm kכl (i.e., bifo di puberty kכmplit), dεn go gro abnכmal tכl. Dɛn kɔl dis gigantism. I nɔ kin bɔku pas akromegali. Sɔm dɔktɔ dɛn kin kɔl am bak "pidiatric acromegaly."

Bɔt if yu growth ɔmon (GH) lɛvɛl go ɔp afta yu growth plet dɛn dɔn lɔk, yu nɔ go gro lɔng. Bɔt da ɔmon de we pasmak kin afɛkt di shep we yu bon dɛn gɛt, di sayz we yu ɔgan dɛn gɛt, ɛn ɔda tin dɛn we kin mek yu gɛt wɛlbɔdi. Dɛn kɔl da sik de akromegali.

Udat kin gɛt akromegali pas ɔlman?

I kin divεlכp pan εni ej afta i bכn. Bɔt bɔku tɛm, dɔktɔ dɛn kin no se i gɛt am pan pipul dɛn we ol bitwin 40 ɛn 50 ia, dat na, we dɛn ol midul ej.

Aw kɔmɔn tin dis?

Akromegali na rili sik we nɔ kin apin so ɔltɛm . Na lɛk 31 pan ɔl 100,000 pipul dɛn nɔmɔ dɛn dɔn gɛt dis sik. So nɔr frayd fɔ no bɔt, bɔt i impɔtant fɔ no bɔt de sayn dɛm.

Aw akromegali kin afɛkt mi bɔdi?

We big pɔsin gɛt akromegali, dat na we di ɔmon we de gro (GH) de bɔku, di bon dɛn, di katilej, di ɔgan dɛn na di bɔdi, ɛn ɔda tisu dɛn kin bigin fɔ big. I klia se chenj dɛn de we pɔsin de luk . Fɔ ɛgzampul:

• Di an ɛn fut dɛn we de big.
• Di yes, lip, ɛn nos we de big.
• Jaw we de kɔmɔt na do, fɔrɛst we dɔn big.

di כmon we de mek wi gכt (GH) de mek wi liva mek כda כmon we dεn kכl Insulin-like Growth Factor 1 (IGF-1) . Dis ɔmon we dɛn kɔl IGF-1 de rili ɛp wi bon ɛn bɔdi tisu dɛn fɔ gro, ɛn i de afɛkt bak di we aw wi bɔdi de kɔntrol di blɔd shuga (glucose) ɛn di fat (lipids). so, we di GH lεvεl dεm de inkrεs, di IGF-1 lεvεl dεm de inkrεs bak. Dis kin mek yu gɛt tin dɛn lɛk Tayp 2 Dayabitis , Ay Blɔd Prɛshɔn (Hypertension) , ɛn At Sik .

Jɔs tink se, jɔs lɛk aw pɔt we dɛn lɛf fɔ rɔn fɔ lɔng tɛm kin west wata, dɛn ɔmon dɛn ya, we dɛn tu ay, kin gɛt difrɛn tin dɛn fɔ du to di bɔdi.

Wetin na di tin dɛn we kin mek pɔsin gɛt akromegali?

di mכst kכmכn tin we kin mek yu gεt akromegali na wan tכmכro na di pituitary gland. Dɛn kɔl dis wan pituitary adenoma . dis tכmכro de mek di pituitary gland kכmכt tu mכch gכt כmon (GH).

Smɔl mɔ bɔt Pituitary Adenoma...

Bɔku tɛm dɛn pituitary adenomas ya nɔ kin fayn. Dat min se dɛn nɔ gɛt kansa. כl di tכmכro dεm we de mek yu gεt akromegali de gro sכmtεm sכmtεm. So, yu nɔ go notis ɛni sayn fɔ dis GH we pasmak fɔ lɔng lɔng tɛm.

dipכnt pan di sayz εn di say we di tכmכro de, i kin prεs pan כda pat dεm na di pituitary gland εn afekt כda כmon dεm we di pituitary gland de mek. If di tumbu big, i kin prɛs bak pan di pat dɛn we de nia di bren, ɛn dis kin mek yu ed at ɛn yu nɔ kin si fayn .

Wetin na di sayn dɛm fɔ Acromegaly?

We big pɔsin gɛt akromegali, i kin afɛkt di bɔdi in bon ɛn tisu dɛn, ɛn dis kin mek dɛn nɔ gro fayn. Dis kin mek yu gɛt dɛn sik ya:

• An ɔ fut dɛn we dɔn big: Sɔntɛm yu ring dɛn kin bigin fɔ tayt, ɛn yu sus saiz, mɔ di wayd, kin go ɔp.
• di chenj dεm na di fes shep: di jaw εria εn/כ fכs de kכmכt כ big.
• di lip, nos, εn/כ tכng we de big.
• We yu de swet pasmak ɔ yu skin gɛt ɔyl.
• Voys de dip ɛn de ala lawd wan.

Ɔda sayn dɛn we de sho se yu gɛt dis sik:

• Ɛd we de at
• Pen na di jɔyn dɛn
• Vishɔn kin chenj
• Inkrεs כkכrεshכn fכ sכm sכm skin tεg dεm
• Numbness na an
• Slip apnea (slip apnea) .
• Carpal tunnel syndrome ɔr yu gɛt prɔblɛm wit yu spɛnal.

Bɔrku tɛm, di sik wae de kam wit akromegali kin kam kwik kwik wan , sɔmtɛm fɔ lɔng tɛm. So i kin at fɔ no dɛn fɔs. Sɔm pipul dɛn kin jɔs notis se dɛn an dɔn big we wan ring we dɛn wɛr tayt ɔ dɛn sus saiz chenj.

Imajin, wan pɔsin de we nem Nilanthi. I dɔn de fil lɛk se in mared ring tayt fɔ sɔm tɛm naw. In sus nɔ tayt lɛk aw i bin de, i tayt smɔl. I bin tink se i jɔs dɔn big. Bɔt di sem tɛm, in padi dɛn de tɔk se in fes difrɛn smɔl pas aw i bin de bifo, ɛn in chin big smɔl. Dis na di smɔl smɔl tin dɛn we dɛn kin notis fɔs.

If yu gɛt dɛn sik ya, i rili impɔtant fɔ tɔk to dɔktɔ.

Aw dɛn kin no se pɔsin gɛt Akromegali?

Bikɔs di sayn dɛm kin apia smɔl smɔl, fɔ lɔng tɛm, i kin at fɔ no smɔl.

Yu dɔktɔ kin sɛn yu to ɛndokrinɔlɔjis , dɔktɔ we spɛshal pan sik dɛn we gɛt fɔ du wit ɔmon. I go mek di diagnosis bay yu mɛdikal histri, klinik ɛgzamin, ɛn spɛshal tɛst (lɛk blɔd tɛst ɛn imej tɛst).

Wetin na di tɛst dɛn we dɛn kin du fɔ no if pɔsin gɛt sik?

If dɛn no se yu gɛt akromegali, yu dɔktɔ kin tɛl yu fɔ du ɔda tɛst fɔ si if di sik dɔn afɛkt ɔda pat dɛn na yu bɔdi. Dɛn tin ya kin bi:

• Wan ɛkokadiogram tɛst fɔ chɛk fɔ si if pɔsin gɛt at prɔblɛm.
• Slip stɔdi tɛst fɔ si if yu de swɛla we yu de slip.
• Kolonoskopi fɔ chɛk di wɛlbɔdi na di kɔlon.
• Chek di bon dɛn wɛlbɔdi wit ɛkstrem rayt ɔ DEXA skan .

Aw dɛn kin trit Akromegali?

Bɔku tritmɛnt dɛn de fɔ akromegali. Dipen pan yu sik ɛn kɔndishɔn, yu dɔktɔ go tɛl yu bɔt di tritmɛnt we go fayn fɔ yu.

Di tritmɛnt dɛm wae dɛn kin yuse mɔr na:

• Ɔpreshɔn
• Mɛrɛsin we dɛn kin gi
• Redyushɔn tɛrapi

Ɔpreshɔn fɔ Akromegali

Bɔku tɛm, ɔpreshɔn kin rili ridyus ɔ mɛn di sayn dɛn we de sho se pɔsin gɛt akromɛgali. Bɔku tɛm, di dɔktɔ dɛn we de du ɔpreshɔn kin yuz wan we we dɛn kɔl transsphenoidal surgery , we na fɔ du di ɔpreshɔn tru di nos ɛn tru di sphenoid saynus (wan ol ples biɛn di nos pasej dɛn, dɔŋ di bren).

Di ditil dɛm fɔ di ɔpreshɔn dipen pan di saiz ɛn di say we di tumbu de. di praymar gol fכ כpεraysh כn na fכ pul di tכmכro kכmplit wan we de mek di εksyכs gכt כmon (GH) prodyuz. If di dɔktɔ we de du di ɔpreshɔn ebul fɔ pul bɔku pat pan di tumbu, yu nɔ go nid ɛni ɔda tritmɛnt. Bɔt if na wan pat pan di tumbu nɔmɔ dɛn pul, yu kin nid mɛrɛsin ɔ redyushɔn tɛrapi fɔ kɔntrol di sayn dɛn ɛn fɔ ridyus di growth ɔmon (GH) we dɛn de mek.

Mɛrɛsin fɔ Acromegaly

Yu dɔktɔ kin gi yu wan mɛrɛsin ɔ sɔm mɛrɛsin dɛn we dɛn jɔyn. Di mεdikeshכn dεm de wok difrεn we dεm fכ nכmal yu bכdi in growth hormone (GH) lεvεl εn rεdכks di simptom dεm. Sɔntɛnde, dɛn kin gi di mɛrɛsin te di tumbu smɔl, so dɔktɔ we de du ɔpreshɔn kin pul am sef wan. Ɔda pipul dɛn kin nid fɔ tek mɛrɛsin fɔ lɔng tɛm fɔ kɔntrol di growth ɔmon (GH) lɛvɛl ɛn di sayn dɛm.

Yu tink se dɛn kin mɛn akromegali kpatakpata?

Sɔntɛnde, dɛn kin mɛn akromegali, bɔt nɔto ɔltɛm. we dεn כpεrayshכn pul wan pituitary tכmכro we de mek yu gεt akromegali, di rεt fכ kכl na bכt 85% fכ sכm tכmכro dεm . fכ big tכmכro dεm, i de bitwin 40% εn 50%.

Mɛrɛsin nɔ kin ebul fɔ mɛn akromegali kpatakpata, bɔt dɛn kin gi pɔsin tritmɛnt fɔ lɔng tɛm ɛn we nɔ gɛt wan prɔblɛm .

Yu tink se dɛn kin mek dɛn nɔ gɛt akromegali?

Bɔt i sɔri fɔ no se natin nɔ de we yu go du fɔ mek yu nɔ gɛt akromegali. Sayɛnsman dɛn stil nɔ shɔ wetin kin mek di pituitary tumors we kin mek pɔsin gɛt akromegaly. Bɔt dɛn biliv se sɔm tin dɛn we kin mek pɔsin gɛt jɛnɛtiks kin ɛp fɔ du dat.

Wetin na di prɔgnosis fɔ akromegali?

De luk fɔ dis kin dipen pan aw di sik kin tranga ɛn aw dɛn kin kɔntrol di sayn dɛm fayn fayn wan wit tritmɛnt. Bɔrku pipul kin si bɔrku ridɔkshɔn pan di sayn dɛm afta tritmɛnt.

If yu nɔ trit am, akromegali kin chenj di we aw yu luk ɛn di shep we yu bon dɛn gɛt bad bad wan. Dɛn sayn ya kin gɛt bɔrku impak pan yu sɛlf-ɛstimɛnt ɛn kwaliti fɔ liv. Sɔpɔt grup dɛn kin ɛp sɔm pipul dɛn fɔ bia wit di prɔblɛm dɛn we kin kam wit akromegali.

Akromegali kin mek yu gɛt prɔblɛm wit yu wɛlbɔdi bak, lɛk at sik ɔ tayp 2 dayabitis, we kin mek yu nɔ gɛt bɛtɛ layf ɛn mek yu layf shɔt. So, i impɔtant fɔ go to dɔktɔ if yu gɛt sɔm sayn dɛn ɛn if yu no se yu gɛt dis sik, fɔ fala di tritmɛnt plan gud gud wan.

Us prɔblɛm dɛn kin apin if dɛn nɔ trit am?

If dɛn nɔ trit am, akromegali kin mek i gɛt prɔblɛm dɛn lɛk:

• Tayp 2 dayabitis
• Ay blɔd prɛshɔn (Hypertension) .
• At sik
• Di sik we de na di at mɔsul (Cardiomyopathy) .
• Atraytis we pɔsin kin gɛt
• Kɔlɔn polip - Dɛn wan ya kin bi kansa if dɛn nɔ trit dɛn.
• Ɔgan dɛn we nɔ de wok fayn

Wetin na di layf we pɔsin we gɛt akromegali kin liv?

Dis kin dipen pan aw di sik tranga ɛn if ɔda wɛl bɔdi prɔblɛm dɛn de, we bɔku tɛm na akromegali we dɛn nɔ trit.

If yu nɔr de kɔntrol yu growth ɔmon (GH) lɛvɛl fayn fayn wan ɛn yu gɛt ɔda tin dɛm lɛk at sik ɛn dayabitis, yu layf kin ridyus bay lɛk 10 ia.

Bɔt if yu gɛt akromegali, dɛn trit yu fayn, ɛn yu gɛt nɔmal growth ɔmon (GH) ɛn IGF-1 lɛvɛl, i go mɔs bi se yu go liv nɔmal layf span.

Ustɛm a fɔ go to dɔktɔ bɔt akromegali?

If yu gɛt sayn dɛm fɔ akromegali, i rili impɔtant fɔ tɔk to dɔktɔ.

If dɛn dɔn no se yu gɛt akromegali, yu go nid fɔ go to yu dɔktɔ ɔltɛm fɔ mek shɔ se yu tritmɛnt de wok fayn fayn wan.

Akromegali na wan sik we nɔ kin apin so ɔltɛm bɔt i kin rili siriɔs. Di gud nyus na dat dɛn kin trit am wit ɔpreshɔn, mɛrɛsin, ɛn/ɔ redyushɔn tɛrapi. If yu dɔn notis se yu an, fut, ɛn/ɔ yu fes de big, tɔk to yu dɔktɔ. I kin du sɔm simpul tɛst fɔ si if di ɔmon we yu de gro (GH) na in de mek yu gɛt di sik.

Fɔ dɔn, mɛsej we yu kin kɛr go na os

• Akromegali na wan sik we nɔ kin apin to big pipul dɛn we kin kam bikɔs di ɔmon we de gro (GH) kin bɔku.
• Di sayn dɛm kin bi we yu an ɛn yu fes kin swel, yu kin swet pasmak, ɛn yu vɔys kin chenj . Dɛn tin ya kin apia smɔl smɔl, so yu nɔ go notis dɛn.
• di men tin we kin mek dis apin na wan tכmכro, we bכku tεm nכ de kεnsar, we de divεlכp na di pituitary gland.
• If yu no am kwik kwik wan ɛn trit yu, dat kin mek yu nɔ gɛt bɔku prɔblɛm dɛn ɛn i kin mek yu layf bɛtɛ.
• If yu gɛt dɛn sik ya, nɔ shem fɔ go to dɔktɔ. Dat na di tin we gɛt sɛns pas ɔl fɔ du.

Duya mɛmba se dis infɔmeshɔn na fɔ infɔmeshɔn nɔmɔ. Dɛn nɔ fɔ ɛva yuz am fɔ tek ples fɔ advays we dɔktɔ dɛn kin gi. If yu gɛt ɛnitin fɔ wɔri bɔt yu wɛlbɔdi biznɛs, duya go to pɔsin we sabi du di wok.

` Akromegali, Grɔw Ɔmon, Pituitary Gland, Gigantism, IGF-1, Ɔmon disɔda, Ɛndɔkrin