Yu kin fil taya ɔltɛm, yu kin fil se yu nɔ gɛt layf, ɛn yu skin kɔlɔ de chenj smɔl smɔl? Sɔntɛm yu gɛt wan strenj krayv fɔ sɔl. Bɔku tɛm wi nɔ kin pe atɛnshɔn to dɛn kayn sayn dɛn ya lɛk aw i nɔmal. Bɔt dɛn tin ya kin bi sayn fɔ wan sik insay wi bɔdi we nɔ kin so bɔku, bɔt i rili impɔtant fɔ no am kɔrɛkt wan. Tide wi de tɔk bɔt dis kayn sik we nɔ kin bɔku, bɔt if dɛn manej am fayn, yu kin liv nɔmal layf. Dat na di sik we dɛn kɔl Addison .
Fɔ tɔk am simpul wan, wetin na Addison’s Disease?
Okay, mek wi ɛksplen dis simpul wan. Wi gɛt tu smɔl smɔl gland dɛn we tan lɛk triangul, we tan lɛk hat, ɔp wi kidni dɛn. Wi kin kɔl dɛn tin ya di adrenal gland dɛn . dis na wan rili imכtant pat pan wi εndokrin sistεm.
Di sik we dɛn kɔl Addison na wan sik we di adrenal gland dɛn nɔ de mek tu impɔtant ɔmon dɛn we na kɔtisol ɛn aldosterɔn .
Wetin wi nid dɛn tu ɔmon ya fɔ?
- Kɔtisol: Dis na ɔmon we impɔtant fɔ layf. I kin ɛp wi bɔdi fɔ bia wit strɛs, lɛk we wi sik, we wi gɛt aksidɛnt, ɔ we dɛn du ɔpreshɔn pan wi. I de ɛp bak fɔ mek di blɔd prɛshɔn, at rit, di imyun sistɛm wok, ɛn di glukɔs na di blɔd.
- Aldosterone: Dis ɔmon de ɛp fɔ balans di minral dɛm we gɛt sɔdiɔm (sɔl) ɛn potashɔm na wi bɔdi. I de kɔntrol bak ɔmɔs wata we wi kidni dɛn de pul as urine. Dis kin afɛkt wi blɔd prɛshɔn bak dairekt wan.
Dɛn kin kɔl am bak di sik we dɛn kɔl Addison’s disease praymari adrenal insufficiency . Wan ɔda tin de we gɛt fɔ du wit dis, we dɛn kɔl sɛkɔndari adrenal insufficiency . insay dis kכndyushכn, di pituitary gland na di bren nכ de rilis inof כmon ACTH , we de mek di adrenal gland dεm fכ prodyuz kכtisol. Bɔt tide wi de tɔk mɔ bɔt di prɔblɛm we kin apin na di adrenal gland dɛnsɛf.
Difrɛns bitwin di sik we dɛn kɔl Addison ɛn di sik we dɛn kɔl Cushing
Yu go kɔnfyus wit dɛn tu nem ya. Dɛn tu tin ya na tin dɛn we rili difrɛn.
| Di kwaliti we pɔsin gɛt | Di Sik we Adisin gɛt | Di sik we dɛn kɔl Cushing’s Syndrome |
|---|---|---|
| Men prɔblɛm | di kכtisol (εn aldosterone) we nכ de na di bכdi. | di kכtisol de inkrεs na di bכdi (Hypercortisolism). |
| Di tin dɛn we kɔmɔn | We yu de lɔs yu wet, yu skin de dak, yu blɔd prɛshɔn go dɔŋ. | We yu de gɛt bɔku bɔku wet, yu fes de rawnd, yu blɔd prɛshɔn go ɔp. |
Udat kin gɛt dis sik pas ɔlman? Aw i kɔmɔn?
Pan ɔl we dis sik kin ambɔg pipul dɛn we ol ɛni ej, i kin apin mɔ pan pipul dɛn we ol bitwin 30 ɛn 50 ia .
Dis na rili wan sik we nɔ kin apin so ɔltɛm . Fɔ ɛgzampul, na Amɛrika, dis sik kin ambɔg lɛk wan pan ɛvri ɔndrɛd tawzin pipul dɛn. Bɔt pipul dɛn de we gɛt dis sik na wi kɔntri bak.
Pipul dɛn de wae gɛt bɔrku risk fɔ gɛt dis sik. Dɛn wan ya na pipul dɛn we gɛt ɔda sik dɛn we dɛn kin gɛt we dɛn de fɛt dɛnsɛf . Dat min se sik dɛn we wi bɔdi in yon imyun sistɛm de atak wi yon sɛl dɛn. If wi gɛt dɛn kayn sik ya, di risk fɔ gɛt di sik we dɛn kɔl Adisin kin bɔku.
- Tayp I dayabitis
- Anemia we kin pwɛl pɔsin in bɔdi
- Grevs in sik
- Tayroyditis we nɔ de mɛn
- Vitiligo - wayt pat pan di skin
- Myasthenia gravis we gɛt di sik
Wetin na di sayn dɛm fɔ Addison in sik?
Insay di sik we dɛn kɔl Addison, bɔku tɛm di damej we di adrenal gland dɛn kin pwɛl kin apin smɔl smɔl, as tɛm de go. So, di sayn dɛm kin apia smɔl smɔl. Dɛn sayn ya kin difrɛn frɔm wan pɔrsin to ɔda pɔrsin.
| Kɔmɔn sayn dɛm wae kin kam smɔl smɔl | |
|---|---|
| Di tin we kɔmɔn pas ɔl | Smɔl smɔl, yu kin taya ɛn taya fɔ lɔng tɛm we yu nɔ kin ɛksplen. |
| Skin kin chenj | Brawn/blak di kɔlɔ we de chenj na di skin, mɔ na say dɛn we gɛt skata, di skin fold (lɛk di armpit, di groin), ɛn di gɔm (Hyperpigmentation). |
| Dijestiv sistɛm | Bɛlɛ de at, nɔs, vɔmit, dayarɛa, nɔ kin want fɔ it, ɛn i nɔ kin gɛt bɔku bɔku bɔdi. |
| Ɔda tin dɛn we de apin | Mɔsul ɛn jɔyn pen, wata we de kɔmɔt na yu bɔdi, diziz we yu tinap (bikɔs yu blɔd prɛshɔn smɔl), yu kin vɛks, yu at pwɛl, yu kin want sɔl pasmak, ɛn yu blɔd shuga nɔ bɔku (haypoglycemia). |
Uman dɛn kin gɛt sɔm sayn dɛn bak lɛk we dɛn nɔ kin gɛt mɔnt ɔltɛm, dɛn bɔdi ia kin lɔs, ɛn dɛn nɔ kin want fɔ du mami ɛn dadi biznɛs igen.
Imejɛnsi sityueshɔn we nid fɔ pe atɛnshɔn: Addisonian Crisis
Sɔntɛnde, mɔ afta yu gɛt siriɔs infekshɔn, aksidɛnt, ɔr strɛs pasmak, dɛn sayn ya kin rili bad wantɛm wantɛm. Dɛn kɔl dis Addisonian Crisis ɔ akyu adrenal fayl . Dis na mɛdikal imejensi we nid fɔ gɛt tritmɛnt wantɛm wantɛm ɛn i kin ivin mek pɔsin in layf de pan denja!
Di sayn dɛm fɔ wan Addisonian kraysis:
- Wan wikɛd tin we pɔsin nɔ go ebul fɔ bia, we nɔ kɔmɔn.
- Wantɛm wantɛm, i kin pen bad bad wan na di ɔda pat na di bɔdi we de dɔŋ, di bɛlɛ, ɔ di leg dɛn.
- Di chenj na yu maynd lɛk fɔ nɔr de rɛst, fɔ kɔnfyus, ɛn fɔ fil se yu de fred.
- Siriv vɔmit ɛn dayarɛa (dis kin mek yu nɔ gɛt wata kwik kwik wan).
- Blɔd prɛshɔn de drɔp tumɔs.
- Nɔbɔdi nɔ kin no natin.
If yu ɔ pɔsin we yu sabi gɛt dɛn sik ya, kɛr am go na di ɔspitul we de nia yu Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm.
Wetin na di tin dɛn we kin mek pɔsin gɛt Addison in sik?
Di men ɛn kɔmɔn tin we kin mek pɔsin gɛt Addison in sik na di ɔtoimyun rεspכns.. Fɔ tɔk am simpul wan, wi yon difɛns sistɛm (immune system) kin mistek atak ɛn pwɛl di ɔda pat pan wi yon adrenal gland dɛn (adrenal cortex). Wi nɔ no yet di rayt rizin we mek dis kin apin. di simptom dεm kin bigin fכ sho afta lεk 90% pan dεn gland dεm ya dεn dכn pwεl. Dis kin tek sɔm mɔnt, ɔ ivin sɔm ia.
Dis na di kɔz fɔ 75% pan di sik pipul dɛm na Addison.
Ɔda tin dɛn we nɔ kin apin so ɔltɛm:
- Tuberculosis: Dis na bin big tin we bin de mek i sik trade. I stil bi wan impɔtant tin we de mek i apin na di divɛlop kɔntri dɛn.
- Infεkshכn dεm we de kam bak: Infεkshכn dεm we gεt fכ HIV/AIDS εn fכn infεkshכn.
- Kansa: Kεnsar sεl dεm de spre frכm כdasay to di adrenal gland dεm.
- Ɛmoraji we de kɔmɔt na di adrenal gland dɛn.
- Ɔpreshɔn fɔ pul di adrenal gland dɛn.
- Amyloidosis: Na sik we wan kayn prɔtin de put insay di ɔgan dɛn ɛn pwɛl dɛn.
Aw fɔ no bɔt dis sik? (Diagnosis) .
Bikɔs di sayn dɛm kin kam sloslo ɛn kin kɔmɔn fɔ bɔrku ɔda sik dɛm, i kin tranga fɔ no bɔt Adisin in sik fɔs. Bɔrku tɛm, dɛn kin no bɔt dis sik "incidentally." Dɔktɔ dɛn kin sɔprayz dis if dɛn si se di sodium nɔ bɔku ɛn di potashɔm bɔku na di blɔd we dɛn de du blɔd tɛst ɔltɛm fɔ ɔda sik. Dɔn bak, we di skin gɛt bɔku bɔku kɔlɔ na wan big sayn we kin mek pipul dɛn tink se i gɛt dis sik.
If yu dɔktɔ sɔspɛkt dis bay di sayn dɛm we yu gɛt, dɛn go ɔda fɔ du sɔm ɔda tɛst fɔ no if yu gɛt di sik.
Test dɛn fɔ no if pɔsin gɛt di sik:
- Blɔd tɛst: Blɔd tɛst de mɛzhɔ di lɛvɛl we sɔdiɔm, potashɔm, kɔtisol, ɛn ACTH ɔmon dɛn de. Insay di sik we dɛn kɔl Addison, di kɔtisol kin smɔl ɛn di ACTH lɛvɛl kin bɔku.
- ACTH stimulation test: Dis na di men test we dɛn kin yuz fɔ kɔnfɔm di diagnosis. Insay dis tɛst, dɛn kin gi di sɛntetik ACTH ɔmon as injɛkshɔn, ɛn dɛn kin mɛzhɔ di kɔtisol lɛvɛl na yu blɔd lɛk wan awa so afta dat. If yu adrenal gland dεm hεlty, yu kכtisol lεvεl fכ inkrεs. Bɔt if i nɔ du dat, i de sho se yu adrenal gland dɛn nɔ de wok fayn.
- Insulin-induced hypoglycemia test: Dɛn kin du dis tɛst fɔ no if yu gɛt prɔblɛm wit di pituitary gland.
- CT skan: Dɛn kin du CT skan fɔ chɛk if yu adrenal gland dɛn dɔn pwɛl, gɛt di sik, ɔ dɛn dɔn smɔl.
Aw dɛn kin trit am?
Di men we fɔ trit Addison in sik na, .Hכmon Riplesmεnt Tεrapi (HRT) na di prכsεs fכ riples di bכdi in כmon dεm we nכ de insay di fכm fכ sεntetik pils.
Bikɔs dis na sik we nɔ de mɛn, yu go gɛt fɔ tek dis mɛrɛsin fɔ di res ɔf yu layf .
- Dɛn kin gi wan mɛrɛsin we dɛn kɔl haydrokɔtizɔn insted ɔf di ɔmon we dɛn kɔl kɔtisol .
- Dɛn kin gi wan mɛrɛsin we dɛn kɔl fludrocortisone insted ɔf di ɔmon we dɛn kɔl aldosterone .
Di doz fɔ dɛn mɛrɛsin ya kin difrɛn frɔm wan pɔsin to ɔda pɔsin. Dɔn bak, yu dɔktɔ kin inkrisayz yu doz fɔ sɔm tɛm fɔ mek yu nɔ gɛt Addisonian kraysis if yu gɛt sɔntin we de mek yu strɛs, lɛk infekshɔn, aksidɛnt, ɔ ɔpreshɔn.
If yu de tek fludrocortisone, yu dɔktɔ go advays yu fɔ ad smɔl ɛkstra sɔl to yu it, mɔ we di wɛda wam ɛn swet ɛn afta yu dɔn du ɛksɛsayz tranga wan.
Liv wit de sik ɛn wetin yu fɔ du
If pɔsin gɛt di rayt tritmɛnt, i go ebul fɔ liv in layf we nɔmal ɛn gɛt wɛlbɔdi . Bɔt i rili impɔtant fɔ mek yu kɔntinyu fɔ tek di kɔrɛkt doz fɔ di mɛrɛsin.
If di doz fɔ di mɛrɛsin tu bɔku, sayd ɛfɛkt dɛn lɛk fɔ fat, tayp 2 dayabitis, ɔstioporosis, ɛn ay blɔd prɛshɔn kin apin. So, i impɔtant fɔ go to yu dɔktɔ ɔltɛm (bɔku tɛm na ɛndokrinɔlɔjis) ɛn du di tɛst dɛn we yu nid fɔ mek yu kɔntinyu fɔ gɛt di kɔrɛkt doz fɔ di mɛrɛsin.
Tin dɛn we yu fɔ du fɔ yu yon sef:
- Ɔltɛm wɛr ID kad ɔ mɛdikal alert breslɛt/nɛklɛs. Dis go ɛp di mɛdikal wokman dɛm fɔ no se yu gɛt Addison in sik if yu lɔs kɔnshɛns pan imejensi.
- Tɔk to yu dɔktɔ bɔt aw fɔ kip kɔtisol shot na yu an if ɛnitin apin. Dɔn bak, tich yu famili ɔ pɔsin we yu lɛk aw fɔ gi yu di shot.
- Aks yu dɔktɔ wetin fɔ du we yu fil sik ɔ yu gɛt bɔku strɛs. If na so i bi, yu go nid fɔ chenj di doz fɔ yu mɛrɛsin.
- Kɔntinyu fɔ go to yu dɔktɔ.
We yu no se yu gɛt wan sik we nɔ de mɛn, dat kin mek yu fil bad. Bɔt di gud nyus na dat, dɛn kin kɔntrol di sik we dɛn kɔl Adisin fayn fayn wan wit mɛrɛsin. Di tin we impɔtant pas ɔl na fɔ de tɔk to yu dɔktɔ ɔltɛm ɛn gɛt di tritmɛnt we yu nid.
Mɛsej we dɛn kin kɛr go na os
- Di sik we dɛn kɔl Addison na wan sik we di adrenal gland dɛn nɔ de mek inof ɔmon dɛn we dɛn kɔl kɔtisol ɛn aldosterɔn.
- Di men sayn dɛm na we yu taya fɔ lɔng tɛm fɔ no rizin, yu skin ɛn yu gɔm kin dak, ɛn yu kin want fɔ it tin dɛn we gɛt sɔl pasmak.
- "Addisonian crisis" na imejensi wae de mek yu layf de pan denja wae nid fɔ gɛt tritmɛnt kwik kwik wan.
- Di tritmɛnt na fɔ tek smɔl ɔmon pils fɔ layf.
- If yu gɛt di rayt tritmɛnt, yu kin liv nɔrmal ɛn wɛl bɔdi layf, bɔt i impɔtant fɔ de tɔk to yu dɔktɔ.
- If yu gɛt dis sik, i rili impɔtant fɔ yu sef fɔ wɛr mɛdikal alert kad ɔ breslɛt ɔltɛm ɛn gɛt imejensi plan.
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