Ɛni difrɛns de pan di we aw yu pikin de du mami ɛn dadi biznɛs? Lɛ wi tɔk bɔt Androgen Insensitivity Syndrome!

we di pikin we de insay di bεlε de gro, sכmtεm sכmtεm sכm sכm tin dεm nכ kin go lεk aw dεn bin de op. Sɔm pikin dɛn kin gɛt smɔl prɔblɛm wit dɛn bɔdi we dɛn bɔn. Ɔ, dɛn bɔdi nɔ kin chenj lɛk aw dɛn bin de tink we dɛn rich di tɛm we dɛn de bɔn. na dεn kayn tεm ya, wi kin tink bכt wan kכndyushכn we dεn kכl `(Androgen Insensitivity Syndrome)`. Nɔ wɔri, wi go tɔk bɔt dis simpul wan, di we we yu go ɔndastand.

Wetin na Andrɔjen Insɛnsitiviti Sindrom?

Fɔ tɔk am simpul wan, Androgen Insensitivity Syndrome (AIS) na wan sik we pikin na man in jɛnɛtiks (i.e., i gɛt X kromozom ɛn Y kromozom), bɔt in bɔdi nɔ de ansa fayn to di man sɛks ɔmon dɛm, androgens . Tink bɔt dis we: smɔl smɔl get dɛn de na wi bɔdi we kin sɛn mɛsej to di sɛl dɛn, ɛn dɛn kin ansa dɛn ɔmon dɛn ya. Insay pɔsin we gɛt AIS, dɛn get ya nɔ de wok fayn.

Dɔktɔ dɛn kɔl dis dizayd we de mek pipul dɛn no difrɛns bitwin man ɛn uman . Dɛn bin de kɔl am testicular feminization syndrome, bɔt dɛn nɔ de yuz da nem de igen. dis kכndyushכn de afekt di we aw di pikin in sεks כgan dεm de divεlכp we i stil de na di bεlε. I kin afɛkt bak di divɛlɔpmɛnt fɔ di kayn we aw pɔsin de du mami ɛn dadi biznɛs we fɔ apin we i yɔŋ. Bɔku tɛm, pipul dɛn we gɛt dis sik nɔ kin ebul fɔ bɔn pikin dɛn we dɛn dɔn big (infertility) .

Yu tink se difrɛn kayn dis de?

Yes, tri men kayn `AIS` de. Ɛni kayn we gɛt difrɛn kwaliti dɛn smɔl.

1. Kɔmplit Andrɔjen Insɛnsitiviti Sindrom (CAIS):

• Dɛn pipul ya kin tan lɛk gyal pikin dɛn ɔlsay na do. Dat min se dɛn bɔdi kin tan lɛk gyal pikin.
• כltu, dεn nכ gεt uman intanεt jεnitalia (i.e. ovaria, fallopian tכb, uterus).
• Mɔs tɛm, dɛn kin mɛn pipul dɛn we gɛt `CAIS` as gyal pikin.

2. Patεal Andrכjen Insεnsitiviti Sεndrכm (PAIS):

• di εksternal jεnitalia dεm nכ kin fulכp divεlכp lεk bכy pikin, כ dεn kin luk lεk gyal pikin, כ dεn kin miks dεn tu, we kin mek i at fכ no klia wan se dεn na man כ uman (ambiguous genitalia).
• Pipul we gɛt `PAIS` sɔm tɛm dɛn kin mɛn dɛn as bɔy pikin ɛn sɔm tɛm dɛn kin mɛn dɛn as gyal pikin.

3. Mild Androjen Insεnsitiviti Sεndrכm (MAIS):

• Dɛn bɔdi kin tan lɛk di wan we man pikin gɛt.
• Bɔt, dɛn nɔ kin ebul fɔ bɔn pikin bak (infertility). Sɔm dɔktɔ dɛn kin tek `MAIS` as pat pan `PAIS` sɛf.

Udat kin gɛt dis sik? Aw i kɔmɔn?

dis `AIS` kכndishכn de kכz fכ difεkt na di `Androgen Receptor (AR) jin` , we de pan di `X` kromozom we de pas frכm di mama to di pikin. biכs dis na `X-linked` jin, if di mama na di kכriכ fכ dis difεktiv jin, in man pikin gεt 1 pan 4 chans fכ divεlכp dis `AIS` kכndishכn. uman pikin dεm kin gεt dis difεktiv jin bak, εn afta dat dεn go bi kכriכg bak, bכt dεn nכ go divεlכp `AIS`.

AIS na wan sik we nɔ kin apin so ɔltɛm . PAIS kin afɛkt lɛk wan pan ɛvri 99,000 man pikin dɛn. CAIS kin afɛkt bitwin tu ɛn fayv pan 100,000 pikin dɛn.

Wetin mek dis de apin? Wetin na di rizin?

as wi bin se, di men rizin fכ dis na abnכmaliti na di `AR` jin na di `X` kromozom. we dis jin nכ de wok fayn, di bכdi nכ kin mek androjen rεsεpכta dεm. dis androgen rεsεpכta dεm na, fכ simpul wan, di tin dεm we de εp di bכdi in sεl dεm fכ ansa man כmon dεm we dεn kכl andrכjen (fכ egzampl , tεstostεron) . so, we dεn rεsεpכta dεm ya nכ de, di bכdi nכ de "rεkכgnεz" di man כmon dεm, we min se ivin if dεn כmon dεm de, dεn nכ de du wetin dεn fכ du.

Wetin na di sayn dɛm fɔ dis?

Di sayn dɛm fɔ AIS kin difrɛn difrɛn wan fɔ di kayn. Bɔt di men tin we ɔl kayn tin kin apin na we pɔsin nɔ kin bɔn pikin .

Pipul dεm we gεt `CAIS` nכ kin gεt bεlε כ gεt dεn patna bεlε. Pan ɔl we dɛn bɔdi we dɛn kin bɔn kin tan lɛk uman in yon, dɛn nɔ gɛt di uman in bɔdi fɔ bɔn pikin dɛn insay. Pipul dɛn we gɛt `PAIS` ɔ `MAIS` dɛnsɛf nɔ kin rili ebul fɔ bɔn pikin. Dɛn kin gɛt rili smɔl penis, ɛn di swɛt we dɛn kin mek kin rili smɔl ɔ dɛn nɔ kin gɛt am.

Ɔda sayn dɛm wae pipul dɛm wae gɛt CAIS kin gɛt na:

• Fɔ bi pɔsin we nɔ kɔmɔn fɔ lɔng pas di avrej gyal pikin we i de yɔŋ.
• We pɔsin nɔ de gɛt mɔnt (Amenorrhea) .
• We pɔsin de bɔn , i nɔ kin gɛt bɛtɛ ia ɔ i nɔ kin gɛt ɛni ia na di an ɛn di say we i de na di bɔdi.
• di vagina we de smɔl ɔ shalo .
• di tεstikul dεm de stil de na di bכdi (dεn nכ de dכn).

Ɔda sayn dɛm wae pipul dɛm wae gɛt PAIS kin gɛt na:

• bifid skrotum na wan kכndyushכn we di tεstikul dεn sheb to tu .
• di klitoris we de mek di klitoris big (Clitoromegaly) .
• di brεst tisu we de big pan bכy pikin dεm (Gynecomastia) .
• Hypospadias na we di urethral opin de ɔnda di penis, nɔto di tip .
• Labial adheshon dɛn we de na di .
• Smɔl penis we nɔmal (Micropenis) .
• Pat pan di testikul dεm we nכ dכn dכn .

Ɔda sayn dɛm wae pipul dɛm wae gɛt `MAIS` kin gɛt:

• di brεst we de big `(Gynecomastia)` .
• Smɔl penis (Micropenis).
• Fɔ gɛt smɔl bɔdi ia .

Aw yu no dis?

Dɔktɔ kin no PAIS we dɛn bɔn am bay we i de luk di pikin in bɔdi. Bɔt if di pikin gɛt CAIS ɔ MAIS, dɛn nɔ go no am te di pikin ol lɛk 11 ɔ 12 ia, we di pikin dɔn rich di tɛm we i de bɔn . Dis na we dɔktɔ kin no if prɔblɛm de.

Fɔ ɛgzampul, pikin we gɛt CAIS nɔ kin gɛt prɛgnɛshɔn ɔ i nɔ kin gɛt pubic hair. Pikin we gɛt MAIS kin gɛt in penis we rili smɔl ɔ i kin gɛt in bɔdi. we uman de bכn, di tεstikul dεm we nכ dכn kin hεnia tru wan wik ples na di bכdi wכl. Sɔntɛnde, dɔktɔ dɛn kin kam fɔ no se pikin gɛt in tɛstikul we nɔ de kam dɔŋ we dɛn du ɔpreshɔn fɔ inguinal hernia .

Us kayn tɛst dɛn kin du?

Fɔ kɔnfɔm dis `AIS` kɔndishɔn, di dɔktɔ go nid fɔ du sɔm tɛst dɛn:

• Blɔd tɛst: Dɛn tin ya kin chɛk di ɔmon lɛvɛl , di sɛks kromozom, ɛn di jenɛtik abnɔmal tin dɛn .
• imej tεst: tεst lεk כ ltra saund kin kכnfכm if di uman riprodaktiv כgan dεm dכn fכm.

If pɔsin na yu famili dɔn gɛt AIS, ɛn yu de plan fɔ bɔn pikin, i go fayn fɔ mek dɛn du tɛst fɔ yu jɛnɛtiks . Dis tɛst kin tɛl yu if yu na pɔsin we gɛt dis abnɔmal jin.

Wetin na di tritmɛnt dɛm fɔ dis?

di tritmεnt fכ AIS na di sεks we dεn gi am we dεn bכn am. Bɔku pan di tritmɛnt dɛn kin bigin afta di pikin dɔn rich di tɛm we i fɔ rich di pikin. Dis kin mek di pikin in bɔdi chenj di we aw i de divɛlɔp ɛn i kin mek di pikin tek pat mɔ pan di tin dɛn we dɛn kin disayd fɔ du fɔ di tritmɛnt.

Bɔt sɔm masta sabi bukman dɛn we sabi bɔt wɛlbɔdi biznɛs biliv se sɔm tritmɛnt dɛn, lɛk fɔ pul di tɛstikul dɛn, dɛn fɔ du bifo dɛn bɔn bikɔs i kin gɛt wan kayn kansa we dɛn kɔl gonadoblastomas na di tɛstikul dɛn we nɔ go dɔŋ. Dɛn kin tɔk bak se dɛn kin du ɔda tritmɛnt dɛn afta we pɔsin dɔn rich in yɔŋ pɔsin.

Di tritmɛnt we dɛn kin pik fɔ pikin dɛn we dɛn mɛn as bɔy pikin:

• Ɔpreshɔn fɔ mek di man dɛn bɔdi fayn. fכ egzampl, `hypospadias ripa` (dεn de arenj bak di urethral opin) כ `orchiopexy` (dεn de arenj bak di tεstikul dεm we nכ dכn dכn insay di skrotum).
• כpεrayshכn fכ ridyus di brεst fכ pul di brεst tisu we pasmak.
• εnia ripa כpεrayshכn na di prכsid כm fכ kכloz di opin כ wik tisu dεm na di bכdi wכl.
• Tɛstostɛron ɔmon tɛrapi .

Di tritmɛnt dɛn we de fɔ pikin dɛn we dɛn adopt as gyal pikin:

• Ɔpreshɔn fɔ pul di man in bɔdi ɔ di ɛksɛs klitoral tisu.
• di we aw dεn nכ de du di vagina dilaysh כn fכ dip di vagina.
• Ɛstrojen ɔmon tɛrapi .

Yu tink se dɛn go ebul fɔ stɔp dis?

No we nɔ de fɔ mek dɛn nɔ gɛt AIS. Bɔt if pɔsin na yu famili gɛt dis sik ɛn yu de wɔri se yu pikin go gɛt dis abnɔmal jin, dɛn kin du jenɛtik tɛst fɔ no if yu na pɔsin we gɛt dis sik.

Aw di wan dɛn we de liv wit dis sik de? (Fyuchɔ Vishɔn)

Pipul wae gɛt AIS kin liv ful, wɛl bɔdi layf . Bɔku pan dɛn kin du wɛl we dɛn de yuz ɔmon tritmɛnt ɛn ɔpreshɔn. Bɔt bikɔs bɔku tɛm AIS kin mek pɔsin nɔ ebul fɔ bɔn pikin, i kin at fɔ bɔku pipul dɛn na dɛn maynd. I kin gɛt big impak bak pan di mental wɛlbɔdi fɔ pikin ɛn yɔŋ pipul dɛn.

If yu nɔ gɛt gonadectomy , yu risk fɔ gɛt tɛstikul kansa de go ɔp bay lɛk 30%.

If mi pikin gɛt AIS, aw a go ɛp?

"Fɔ tek kia ɔf di pikin in maynd wɛlbɔdi na big pat fɔ manej AIS."

If yu pikin gɛt AIS, i impɔtant fɔ gɛt strɔng sɔpɔt sistɛm fɔ ɔndastand dɔktɔ, padi, ɛn fambul. We yu jɔyn sɔpɔt grup dɛn, dat kin ɛp yu pikin bak fɔ sheb in ɛkspiriɛns ɛn prɔblɛm dɛn wit ɔda pipul dɛn we de go tru di sem tin.

As yu pikin de kam insay di yɔŋ pɔsin, ɛn bigin fɔ no se in bɔdi nɔ de chenj lɛk aw dɛn bin de tink, i rili impɔtant fɔ tɔk to dɛn bɔt AIS .

Aw yu de dil wit AIS as big pɔsin?

Fɔ liv wit AIS as big pɔsin kin tranga. E kin tranga fɔ gɛt nɔrmal sɛks layf, fɔ fɛn patna wae ɔndastand ɛn gri wit yu sik, ɛn wae yu nɔr ebul fɔ bɔn pikin kin gɛt bɔrku saykilɔjik impak pan bɔrku pipul dɛm.

If yu gɛt AIS, i kin fayn fɔ tɔk to pɔsin we de gi advays ɔr tritmɛnt bɔt yu ɛkspiriɛns. Yu kin kɔnɛkt bak wit ɔda pipul dɛn we gɛt AIS na sɔpɔt grup dɛn.

Fɔ dɔn, tin dɛn we wi fɔ mɛmba

Androgen Insensitivity Syndrome (AIS) na wan sik we pɔsin in jɛnɛtiks man bɔt i nɔ de ansa to man ɔmon. Dis kin mek dɛn bɔdi kin tan lɛk uman in bɔdi, ɔ dɛn kin gɛt man ɛn uman kwaliti dɛn. Dis sik kin kam wit difrɛn prɔblɛm dɛn. So, i rili impɔtant fɔ mek pipul dɛn we gɛt AIS tɔk to dɛn dɔktɔ ɔltɛm ɛn gɛt strɔng saykilɔjik sɔpɔt. If dɛn gi dɛn di rayt advays fɔ mɛn dɛn ɛn di wan dɛn we dɛn lɛk de sɔpɔt dɛn, dɛn pipul ya kin liv fayn layf bak.

` Androgen insensitivity syndrome, AIS, seksual divεlכpmεnt, כmon, jεnεtik sik dεm, kromozom, infεliti, jεnital, puberty, jεnεtik tεst