Sɔm pan di mɛrɛsin dɛn we yu kin yuz kin afɛkt di bren? (Lɛ wi lan bɔt Anticholinergic Medications)

If yu opin yu mɛrɛsin kabinɛt na os, yu go mɔs fɛn wan pan dɛn kayn mɛrɛsin ya. Wi de tɔk bɔt sɔm pan de mɛrɛsin wae dɛn kin yuse fɔ alɛji, pwɛl hat, pen wae nɔr de dɔn, nɔs, ɔr nɔr kin slip. Dis na drɔgs we wi dɔn de yuz fɔ lɔng lɔng tɛm. Bɔt nyu risach dɔn sho se if wi yuz dɛn mɛrɛsin ya fɔ lɔng tɛm, dat nɔ go so gud fɔ wi bren wɛlbɔdi. I kin ivin mek yu gɛt dis maynia sik , we na sik we de mek yu nɔ ebul fɔ mɛmba tin dɛn. So lɛ wi tek wan luk pan wetin na dɛn anticholinergic drɔgs ya, aw dɛn kin afɛkt di bren, ɛn aw fɔ manej dɛn sef wan.

Wetin na dɛn anticholinergic mɛrɛsin ya rili?

Fɔ tɔk am simpul wan, dɛn kin sheb dɛn mɛrɛsin ya to tu men grup dɛn. di fכs kεtכgrεf na dεn wan dεm we wi de yuz intenshכnal fכ achy anti-cholinergic ifekt. di sεkכn kategori na dεn wan dεm we dεn gi fכ כda praymar pכyz, bכt dεn gεt strכng anti-cholinergic ifekt as sayd ifekt. Di tebul we de dɔŋ ya de sho sɔm pan di kɔmɔn tin dɛn we dɛn kin yuz dɛn mɛrɛsin ya.

Aw dɛn drɔgs ya kin afɛkt wi bren?

I rili simpul. We dɛn anti-cholinergic drɔgs ya go insay di bren, dɛn kin blok wan kemikal we dɛn kɔl acetylcholine . dis asetilkolin na nyurotransmitta we implεnt fכ mek bכku nyuron dεm na di bren wok. Tink bɔt yu bren lɛk big post ɔfis. Acetylcholine na wan rili impɔtant mɛsenja insay am. Na in de ɛp fɔ kip mɛmori, kip infɔmeshɔn na shɔt tɛm mɛmori, ɛn ɔganayz am to lɔng tɛm mɛmori. So wetin dɛn drɔgs ya de du na fɔ ambɔg di wok we da mɛsenja de du. if dεn nכ stכp am kכmplit, dεn de ridyus di aktiviti fכ dεn nyuron dεm bכku bכku wan.

Us ifɛkt we yu de yuz dɛn tin ya kin du to di we aw yu bren de wok?

Risach dɔn sho se dɛn mɛrɛsin ya nɔr rili fayn fɔ yu mɛmori ɛn tink. Na di mɔ yu de yuz dɛn fɔ lɔng tɛm, na di mɔ i go at fɔ rivɛns di ifɛkt dɛn. Lɛ wi brok dis risk dɔŋ to tri tɛm. 1. I go afɛkt am wantɛm wantɛm: Ivin if yu tek dis mɛrɛsin wan tɛm, yu kin gɛt prɔblɛm wit mɛmori. Wi nɔ tink se if yu tek am wan tɛm, dat go mek yu gɛt damej fɔ ɔltɛm. Bɔt ivin if yu yuz am fɔ shɔt tɛm, dat kin mek yu nɔ mɛmba fayn. 2. Short term long term effect: Imajin se yu dɔn de tek dis mɛrɛsin fɔ sɔm mɔnt . If na so i bi, afta yu dɔn stɔp fɔ tek di mɛrɛsin, i kin tek sɔm mɔnt fɔ mek di tin dɛn we kin apin to pɔsin nɔ mɛmba igen. Bɔrku tɛm, na klinik, dɛn kin ri-evalyu di mɛmori ɛn tink skil dɛm fɔ di sikman at le tri mɔnt afta i dɔn stɔp fɔ tek dis kayn mɛrɛsin. 3. Di tin dɛn we kin apin to pɔsin fɔ lɔng tɛm: Pruf we dɛn dɔn gɛda fɔ lɔng lɔng tɛm sho se dɛn mɛrɛsin ya we kin mek pɔsin nɔ gɛt kɔlin kin gɛt sɔntin fɔ du wit dis maynia sik , mɔ di sik we dɛn kɔl Alzaima .

Udat de pan denja fɔ gɛt dɛn tin ya?

Tu men tin dɛn kin afɛkt dis.

• Ej : As wi de ol, wi kin fil mɔ bɔt di bad tin dɛn we ɛni mɛrɛsin kin du. Wi bɔdi nɔ tan lɛk we wi bin yɔŋ, wi bɔdi kin tek lɔng tɛm fɔ mek i wɛl as wi de ol. So, wi nid fɔ tek tɛm mɔ wit wi mɛrɛsin dɛn. Dis na tru mɔ fɔ anti-cholinergic mɛrɛsin dɛn.

• Jɛnɛtik prɛdispɔzishɔn : Sɔm pipul dɛn kin gɛt Alzaima sik. dis na biכs fכ wan jin vεryכnt we dεn kכl ApoE4 . Risach dɔn sho se pipul dɛn we gɛt dis jin kin gɛt mɔ risk fɔ lɛ dɛn nɔ mɛmba mɔ ɛn mɔ we dɛn de tek mɛrɛsin dɛn we de mek dɛn nɔ gɛt kɔlin.

Wan stɔdi dɔn sho se pipul dɛm wae dɔn pas 55 ia wae yuse di ikwal fɔ tek wan strɔng anti-cholinergic drɔg na di minimum rεkomεndεd de doz fɔ 3 ia fɔ 10 ia bin gɛt 50% inkris risk fɔ gɛt dis maynia sik.

So wetin pipul dɛn we de yuz dis mɛrɛsin fɔ du?

Di tin we impɔtant pas ɔl na fɔ nɔ ɛva stɔp fɔ tek ɛni mɛrɛsin we yu dɔktɔ dɔn tɛl yu. If yu du dat, dat kin mek yu sik wɔs. Imajin se yu gɛt bad bad alɛji wantɛm wantɛm ɛn yu nid fɔ tek mɛrɛsin da tɛm de. Fɔ tek am wan tɛm nɔto big tin. Di prɔblɛm na fɔ yuz am bɔku tɛm ɛn fɔ lɔng tɛm. Wetin yu fɔ du na fɔ tɔk opin wan wit yu dɔktɔ bɔt di mɛrɛsin dɛn we yu de tek. "Dɔkta, dis mɛrɛsin we a de tek gɛt anti-cholinergic ifɛkt? A fɔ kɔntinyu fɔ tek am? Ɛni ɔda opshɔn de fɔ mi?" Aks yusɛf. Ɔl togɛda, if yu de wɔri bɔt yu bren wɛlbɔdi, i bɛtɛ fɔ lɛ yu nɔ tek mɛrɛsin dɛn we gɛt anti-cholinergic ifɛkt as yu ebul.

Us ɔda mɛrɛsin dɛn kin yuz insted ɔf dis mɛrɛsin?

Laki, tide wi gɛt ɔda, sef opshɔn fɔ bɔku pan dɛn kɔndishɔn ya.

Prɔblɛm dɛn we pɔsin kin gɛt we i nɔ ebul fɔ slip

Di bɛst we fɔ du dis na fɔ mek yu gɛt gud abit fɔ slip. Go na bed di sem tɛm ɛvride. Stɔp fɔ luk yu fon ɔ TV bifo yu go slip. If yu nɔ ebul fɔ slip insay 15 minit afta yu dɔn go slip, grap ɛn du ɔda tin na dak ples we yu nɔ gɛt yu fon fɔ 15 minit bifo yu go bak na bed. If nid de, tɔk to yu dɔktɔ bɔt aw fɔ yuz sɔntin lɛk melatonin .

Wɔri ɛn Pwɛl hat

Bɔrku ɔda mɛrɛsin de wae nɔr gɛt anti-cholinergic ifekt fɔ dɛn sik ya. Fɔ ɛgzampul, dɛn kin yuse mɛrɛsin lɛk Duloxetine fɔ ɔl tu di pwɛl hat ɛn pen. Fɔ advays pɔsinNa tin bak we rili pawaful.

I nɔ izi fɔ kɔntrol di we aw yu de pis

Naw wan nyu jɛnɛreshɔn mɛrɛsin de fɔ dis bak we nɔ gɛt di anti-cholinergic risk dɛm. Mirabegron na wan pan dɛn mɛrɛsin dɛn de.

Pen we kin de fɔ lɔng tɛm

Fizik tritmɛnt fɔ bi di men tritmɛnt fɔ bɔku pan di sik dɛm we de mek pɔsin fil pen we nɔ de dɔn. Pruf de fɔ se fizik tritmɛnt kin ridyus pen pas mɛrɛsin.

Alɛji dɛn we pɔsin kin gɛt

Bɔku nyu klas dɛn de fɔ antihistamin we de na famasi dɛn. Sɔm ɛgzampul dɛn na Sɛtirizin , Fɛksofenadin , ɛn Lɛvosɛtirizin . Bɔt tek tɛm if yu bay sɔm kɔf ɛn kol mɛrɛsin frɔm di famasi wit di sɔfix "DM" na di ɛnd pan di nem. Bɔku tɛm dɛn kin gɛt difenhaydramin . Anticholinergic, mɛrɛsin, bren wɛl bɔdi, dis maynia sik, mɛmori lɔs, fɔgɛt, sayd ɛfɛkt, sayd ɛfɛkt, Alzaima