Yu tink se di blɔd we yu de mek de go dɔŋ? Lɛ wi tɔk bɔt dis denja sik we dɛn kɔl Aplastic Anemia!

Yu kin fil bak taya ɛn taya ɔltɛm? Yu kin si am se i nɔ kin izi fɔ yu fɔ blo ivin afta yu dɔn du smɔl tin? Ɔ yu jɔs de gɛt brus ɛn blɔd de kɔmɔt ɔlsay na yu bɔdi? Sɔntɛnde, wi nɔ kin pe atɛnshɔn tumɔs to dɛn tin ya as nɔmal tin. Bɔt sɔm tɛm dɛn kin gɛt sɔntin we rili siriɔs we dɛn ayd biɛn dɛn sayn ya. Aplastic Anemia na wan pan dɛn kayn sik ya we nɔ kin bɔku, dat na, dɛn nɔ kin si am bɔku tɛm, bɔt i kin bi sik we rili denja. So tide wi go tɔk bɔt dis ditayli ɛn simpul wan, so dat yusɛf go ɔndastand dis mɔ.

Fɔ tɔk am simpul wan, wetin na aplastik anemia?

Fɔ tɔk am simpul wan, aplastik anemia na we di bon mɛro we de insay wi bɔdi nɔ de wok fayn. Yu no, di pat pan wi bon dɛn we dɛn kɔl bon mɛro na in de mek di rɛd blɔd sɛl dɛn, wayt blɔd sɛl dɛn, ɛn di pletlɛt dɛn we wi bɔdi nid. So, aplastic anemia kin apin we di bon mכro nכ kin mek dεn sεl dεm ya fayn fayn wan.

I tan lɛk se blɔd faktri de stɔp wantɛm wantɛm. Wetin kin apin da tɛm de? Di bɔdi kin lɔs di blɔd sɛl dɛn we i nid. Dis kin mek yu gɛt siriɔs infɛkshɔn , i kin mek i nɔ izi fɔ lɛ yu stɔp fɔ blɔd, ɛn i kin mek yu gɛt ɔda prɔblɛm dɛn lɛk at sik. Tritmɛnt dɛn de fɔ kɔntrol di sik dɛn. Bɔt di wangren we fɔ mɛn am kpatakpata na fɔ transplant stem sɛl .

Aw dis sik kin kɔmɔn? Yu tink se wi fɔ fred so?

Fɔ tru, dis sik we dɛn kɔl Aplastic Anemia nɔ kin bɔku smɔl . Dat min se nɔto sik we de ambɔg ɔlman. Fɔ ɛgzampul, na Amɛrika, na bitwin 300 ɛn 900 pipul dɛn nɔmɔ dɛn kin gɛt dis sik ɛvri ia. Insay Yurop, stɔdi dɔn sho se dis sik kin afɛkt lɛk tu pipul dɛn pan wan milyɔn.

Pan ɔl we i kin afɛkt ɛnibɔdi we ol ɛni ej, i kin bɔku pan pipul dɛn we ol bitwin 15 ɛn 25 ia ɛn pan pipul dɛn we dɔn pas 60. So, nɔ wɔri fɔ lɛ yu fil taya ɔltɛm ɛn de wɔnda if yu gɛt dis sik. Bɔt, i impɔtant fɔ no bɔt di sayn dɛm we de sho se yu gɛt dis sik.

Wetin na di sayn dɛm fɔ Aplastic Anemia?

De sayn dɛm fɔ dis sik nɔr kin apin wan tɛm. Bɔku tɛm, dɛn sik ya kin apin smɔl smɔl fɔ sɔm wik ɔ mɔnt. So yu nɔ go notis di difrɛns fɔs. Bɔt sɔm pipul dɛn kin gɛt siriɔs sik wantɛm wantɛm. Chek fɔ si if yu gɛt ɛni wan pan dɛn sik ya:

• Vayral infεkshכn (lεk di flu εn kol) kin apin bכku bכku wan, εn i kin tek lεng tεm fכ hεl pas aw i kin bi.
• Fɔ fil ɔltɛm fɔ taya pasmak ɛn taya.
• Brus kin apin ɔlsay na di bɔdi, ɔ ivin smɔl wund kin tek lɔng tɛm fɔ lɛ i nɔ blɔd igen.
• Fɔ fil se i nɔ izi fɔ blo (dyspnea) ., mɔ we yu de du smɔl smɔl wok dɛn.
• I tan lɛk se di kɔlɔ we di skin gɛt pas aw i kin bi.
• Diziz we pɔsin kin gɛt.
• Ed de at.
• Fiva.

Mɛmba se sɔm pan dɛn sayn ya kin kam bak bikɔs ɔf ɔda sik dɛn we nɔ kin rili siriɔs. Fɔ ɛgzampul, i kɔmɔn fɔ fil taya ɛn gɛt fiva we yu gɛt kol. So nɔr panik if yu gɛt wan ɔr tu pan dɛn sik ya ɛn yu tink se yu gɛt aplastic anemia. Bɔt if yu dɔn de fil bad fɔ sɔm wiks ɛn yu de fil taya ɔltɛm we yu nɔ go ebul fɔ bia, i go mɔs bi se yu go to dɔktɔ fɔ advays.

Wetin mek aplastik anemia kin apin? Wetin na di tin dɛn we kin mek i apin?

Infakt, masta sabi pipul dɛn stil nɔ no bɛtɛ bɛtɛ wan wetin mek sɔm pipul dɛn kin gɛt aplastic anemia. Bɔt bɔku tɛm na bikɔs wi yon imyun sistɛm —di sistɛm we de protɛkt wi frɔm sik—nɔ de ɔndastand wi fayn ɛn atak wi yon bon mɛro, ɛn pwɛl di stem sɛl dɛn we de de. Na dɛn stem sɛl ya de mek nyu blɔd sɛl dɛn.

Apat frɔm dat, bɔku ɔda rizin dɛn kin afɛkt dis:

Sɔm sik dɛn we pɔsin kin gɛt:

• Autoimmune diseases , lɛk lupus, na sik dɛn we wi imyun sistɛm kin atak wi yon bɔdi.
• Sɔm vayral infɛkshɔn, fɔ ɛgzampul, vayrɔs dɛn lɛk Epstein-Barr vayrɔs, saytomegalovayrɔs (CMV), parvovayrɔs B19 , ɛn human immunodeficiency virus (HIV) .
• Paroxysmal nocturnal hemoglobinuria na wan sik we dɛn kin gɛt we di rɛd blɔd sɛl dɛn kin brok kwik kwik wan.
• Sɔntɛnde, bɛlɛ kin bi wan tin we kin mek dis apin, bɔt i nɔ kin apin so ɔltɛm.

Di kɔndishɔn dɛn we kin kɔmɔt frɔm jɛnɛreshɔn dɛn:

Na sɔm pipul dɛm, aplastic anemia kin gɛt fɔ du wit inhɛrit bon mɛrɔ failure syndrome. Dɛn kɔl dɛn tin ya ‘inherited bone marrow failure syndromes’. Sɔm ɛgzampul dɛn na:

• Fankɔni anemia
• Diskeratosis we dɛn bɔn wit
• Shwachman-Diamond sindrom we gɛt di sik
• Daymɔnd-Blakfan anemia
• Piɔsɔn sindrom

Sɔm tritmɛnt dɛn we pɔsin kin gɛt:

Sɔm mɛrɛsin dɛn kin mek bak di risk fɔ gɛt dis sik.

• Sɔm tritmɛnt fɔ ɔtoimyun sik dɛn.
• Redyushɔn ɛn kemotɛrapi fɔ kansa. Bikɔs dɛn tritmɛnt ya rili pawaful, dɛn kin pwɛl di bon mɛrɔ.

Dɔn bak, if pɔsin de pan sɔm kemikal dɛn we dɛn kɔl kansa , lɛk asɛnik ɛn bɛnzin , fɔ lɔng tɛm, dat kin mek dis prɔblɛm bɔku.

Us prɔblɛm dɛn dis kin mek?

Pɔsin we gɛt aplastik anemia kin gɛt prɔblɛm dɛn lɛk dis, sɔm pan dɛn kin mek in layf de pan denja:

• Anemia: Dis min se di blɔd volyum na di bɔdi de go dɔŋ. Dis kin mek tin lɛk fɔ taya pasmak ɛn fɔ mek i nɔ izi fɔ blo.
• Sivεr infεkshכn: As di wayt blכd sεl dεm de dכn, di ebul fכ rεst di sik de dכn.
• Blɔd we de kɔmɔt pasmak: Bikɔs di pletlɛt dɛn de go dɔŋ, i kin tek lɔng tɛm fɔ mek blɔd klot.
• At ritm irɛgyulariti (Arrhythmia) ɔ at nɔ de wok fayn.
• Maylodysplastic syndrome na wan kכndyushכn we di sεl dεm na di bon mכro de gro abnכmal wan.

Aw dɛn kin no se pɔsin gɛt Aplastic Anemia?

Dɔktɔ dɛn kin no dis sik bay we dɛn de chɛk yu, du blɔd tɛst, ɛn sɔntɛnde dɛn kin tɛst yu jɛnɛtiks. Dɛn tɛst ya kin bi:

• Kɔmplit blɔd kɔnt (CBC) wit difrɛns: Dis de mɛzhɔ di nɔmba fɔ di rɛd sɛl dɛn, ɔl di fayv kayn wayt sɛl dɛn, ɛn di pletlɛt dɛn we de na yu blɔd.
• Peripheral blood smear: Dɛn kin tek blɔd sɛmpul ɛn chɛk am ɔnda maykroskɔp fɔ chɛk aw blɔd sɛl ɛn pletlɛt dɛn de luk ɛn shep.
• rεtikulכsayt kכnt: dis de mכsu di nכmba fכ nyu fכm, immature rεd bכdi sεl dεm (rεtikulכsayt dεm).
• di bon mכro aspirash כn εn bon mכro bayopsi: Insay dis, dεn kin tek sכm sכm sכm sכm bon mכro, we kin kכmכt frכm di hip bon, כnda anεsthεsia. Dɔn dɛn kin chɛk am ɔnda maykroskɔp fɔ si di rayt we aw di bon mɛrɔ de. Dis na di men tɛst fɔ kɔnfirm di diagnosis.

Wetin na di tritmɛnt dɛn?

Di tritmɛnt we dɛn kin pik kin difrɛn difrɛn wan fɔ di kayn sik we yu gɛt. Fɔ ɛgzampul, sɔm pipul dɛn kin gɛt aplastic anemia as a rizulta fɔ tritmɛnt fɔ kansa ɔ tritmɛnt fɔ ɔtoimyun sik dɛn. If dɛn kayn tin ya apin, dɔktɔ dɛn kin tray fɔ chenj dɛn tritmɛnt dɛn de.

If yu blɔd sɛl kɔnt smɔl pas aw i fɔ bi bɔt yu nɔ gɛt ɛni big big sayn, yu dɔktɔ kin se yu gɛt mɔdaret aplastik anemia. If na so i bi, i go mɔs bi se yu dɔktɔ go de wach yu wɛlbɔdi ɛn blɔd ɔltɛm. Dis we ya, yu kin tek akshɔn kwik kwik wan if i tan lɛk se yu sik de wɔs.

Di tritmɛnt fɔ mɔ siriɔs kes dɛm we gɛt aplastik anemia na:

• Immunosuppressants: Dɛn mɛrɛsin ya de wok bay we dɛn de kɔntrol di wok we yu imyun sistɛm de du ɛn stɔp am fɔ atak yu bon mɛrɔ. εgzampl dεm fכ dεn dεm ya na antitaymosayt globulin injεkshכn (Atgam®) εn sayklosporin (Sandimmune®) .
• Blɔd we dɛn kin gi:Dis min se dɛn fɔ chenj di rɛd blɔd sɛl dɛn ɛn di pletlɛt dɛn we dɔn pwɛl. Dis nɔ kin mɛn di sik, bɔt i kin ɛp fɔ mek di sik nɔr de igen.
• Antibayɔtik: Pipul dɛn we gɛt aplastik anemia kin gɛt bɔku bɔku sik dɛn we dɛn kin gɛt frɔm baktriyal. So, dɛn kin gi antibayɔtik fɔ mɛn infɛkshɔn.
• Allogeneic stem cell transplantation: Dis na di men tritmɛnt fɔ dis sik. insay dis prosidur, dεn kin transplant hεlty stεm sεl dεm frכm hεlty dכna (bכku tεm na in famili mεmba כ wan mach dכna) insay di sikman in bon mכro we dεn dכn dכn. Afta dis, nyu blɔd sɛl dɛn we gɛt wɛlbɔdi kin bigin fɔ mek.

Wetin na di sayd ɛfɛkt dɛm we di tritmɛnt kin gɛt?

Di sayd ɛfɛkt dɛn bak kin difrɛn difrɛn wan dipen pan di tritmɛnt:

• Graft-versus-host disease: Dis na komplikashכn we kin apin we dεn de transplant allogeneic stεm sεl . Dis min se di sɛl dɛn we dɛn transplant de wok agens di pɔsin in bɔdi.
• Di mɛrɛsin dɛn we de mek di bɔdi nɔ gɛt di sik kin mek pɔsin gɛt di sik.
• di ayron lεvεl dεm we de go כp na di bכdi bikoz fכ di blכd we dεn de transfyushכn bכku tεm (hεmokromatosis / ayכn כvalod).

Yu tink se dɛn go ebul fɔ stɔp dis?

Bɔt i sɔri fɔ no se naw, dɛn nɔ no we fɔ mek dɛn nɔ gɛt aplastik anemia.

Yu tink se dɛn kin mɛn am kpatakpata?

Yes, insay sɔm kes dɛm, if dɛn transplant allogeneic stem cell fayn fayn wan, i kin mɛn dis sik kpatakpata. Jɛnɛral wan, pikin ɛn pipul dɛm wae nɔr rich 40 ia kin gɛt dis tritmɛnt pas big pipul dɛm.

Wetin na di chans fɔ mek pɔsin nɔ day?

Dis rili dipen pan bɔku tin dɛn. Yu ej, di tritmɛnt we yu de gɛt, aw yu sik bad, ɛn ɔda tin dɛn Wan stɔdi sho se ɔltogɛda, 96% pan pipul dɛn bin liv afta dɛn dɔn transplant dɛn stem sɛl. Di sem stɔdi dɔn sho bak se 100% pan di pikin ɛn big pipul dɛn we nɔ rich 40 ia yet bin de alayv fayv ia afta dɛn dɔn trit dɛn.

Bɔt dɛn statystik ya kɔmɔt frɔm di tin dɛn we bɔku pipul dɛn dɔn ɛkspiriɛns. Sɔntɛm dɛn nɔ go afɛkt yu di sem we. If yu gɛt ɛni kwɛstyɔn bɔt dis, i go fayn fɔ mek yu tɔk to yu dɔktɔ. I kin gi yu infɔmeshɔn we fit yu sityueshɔn.

If a gɛt Aplastic Anemia, aw a go tek kia ɔf misɛf?

If yu gɛt dis sik, e fayn fɔ kia fɔ yusɛf fayn fayn wan. E fayn fɔ fala yu dɔktɔ in tritmɛnt plan kɔrɛkt wan ɛn fɔ pe atɛnshɔn to yu sik dɛn. Yu kin du dɛn tin ya bak:

• Nɔ du tin dɛn we go mek yu wund mɔ. Yu de pan ay risk fɔ mek yu blɔd kɔmɔt. So, i go fayn fɔ mek yu nɔ de nia spɔt dɛn lɛk rɔgbi, ɔki, ɛn rɛslɛshɔn.
• Protɛkt yusɛf frɔm vayrɔs ɛn jem.Yu kin gɛt infɛkshɔn mɔ. Aks yu dɔktɔ bɔt us vaysin dɛn we fayn fɔ yu. Was yu an ɔltɛm ɛn nɔr de nia pipul dɛm wae sik (lɛk di wan dɛm wae gɛt kol, flu, ɔr bɛlɛ at).
• Gɛt inof rɛst. Bikɔs anemia na wan prɔblɛm we kin apin to dis, yu kin fil taya bad bad wan ɛn yu nɔ kin ebul fɔ blo fayn. I kin at bak fɔ du wok dɛn we wi kin du ɛvride. So, rɛst ɛn slip fayn we nid de, nɔto we yu ebul.
• It tin dɛn we go mek yu gɛt wɛlbɔdi. If yu it tin dɛn we nɔ gɛt bɔdi, vɛjitebul, frut, ɛn ɔl di tin dɛn we yu kin it, dat kin ɛp fɔ mek yu gɛt mɔ trɛnk. If yu kin gɛt advays frɔm pɔsin we sabi bɔt it, yu kin lan aw fɔ gɛt di bɛst pan di it dɛn we yu de it.
• Gɛt sɔm ɛksesaiz. Layt ɛksesaiz kin ɛp fɔ ridyus strɛs. Bɔt mek shɔ se yu tɔk to yu dɔktɔ bifo yu bigin fɔ du nyu ɛksesaiz.

Ustɛm yu fɔ go to dɔktɔ?

Kɔl yu dɔktɔ wantɛm wantɛm if dis kes:

• If yu gɛt fiva we pas 38 digri sɛlshiɔs (100.4 digri F) ɔ pas dat .
• If yu sik dɛn de wɔs.

Us kwɛstyɔn dɛn a fɔ aks di dɔktɔ?

If yu gɛt aplastic anemia, yu kin aks yu dɔktɔ dɛn kwɛstyɔn ya:

• Wetin na di tin we go mek a gɛt dis sik?
• Yu tink se di sik we a gɛt siriɔs?
• Us tritmɛnt dɛn yu kin advays?
• Wetin na di sayd ɛfɛkt dɛm we di tritmɛnt kin gɛt?
• A nɔ gɛt ɛni simptom. A go nid tritmɛnt?
• A gɛt sɔm sayn dɛn. Wetin na di tritmɛnt dɛn we a kin gɛt?

Yu tink se Aplastic Anemia na kansa?

Nɔ, aplastik anemia nɔto kansa. Bɔt sɔm pipul dɛn we gɛt aplastik anemia kin gɛt wan kayn blɔd kansa we dɛn kɔl lukimiya .

Aplastic anemia na wan sik we nɔ kin apin so ɔltɛm bɔt we kin rili siriɔs. I kin apin we yu imyun sistɛm atak yu yon bon mɛrɔ, ɛn stɔp am fɔ mek di blɔd sɛl ɛn pletlɛt dɛn we yu bɔdi nid. Bɔku tin dɛn de we kin mek yu gɛt dis sik, so yu kin wɔri ɛn fred bɔt am. Bɔt pan ɔl we dɔktɔ dɛn nɔ go ebul fɔ fɛn patikyula tin we mek i sik, dɛn kin trit di sik ɛn sɔntɛnde i kin mɛn. If yu gɛt aplastic anemia, yu dɔktɔ go ɛksplen di tritmɛnt dɛn we fayn fɔ yu ɛn di sayd ɛfɛkt dɛn we dɛn kin gɛt. So, gɛt maynd ɛn fala yu dɔktɔ in advays.

Wan Mɛsej we Wi De Tek na Os

Aplastic Anemia kin mek yu fred we yu yɛri di nem. Bikɔs na siriɔs kɔndishɔn. Bɔt mɛmba se tritmɛnt de fɔ am. If yu no di sik kwik kwik wan, go to dɔktɔ, ɛn bigin fɔ trit yu, bɔku tɛm yu kin kɔntrol dis sik, ɛn ivin mɛn am.

Di tin we impɔtant pas ɔl na dat if yu taya we yu nɔ ebul fɔ ɛksplen, yu de sik ɔltɛm, ɔ yu de blɔd we nɔ kɔmɔn, nɔ jɔs ignore am ɛn go to dɔktɔ fɔ mek dɛn chɛk yu. Di kwik we yu no am, na di mɔ yu go gɛt di tritmɛnt we go wok fayn. Nɔto yu wan de, ɛn dɔktɔ dɛn, fambul dɛn, ɛn padi dɛn ɔl de fɔ ɛp yu pan dis waka.

` Aplastik Anemia, Aplastik Anemia, Anemia, Bɔn Mɛro, Blɔd Sik, Stem Sɛl Transplant, Imyun Sistɛm