Na nɔmal tin fɔ fil smɔl frayd ɛn fred we yu ɔ pɔsin we yu lɛk de kam fɔ bigin tritmɛnt fɔ kansa. Ɛspɛshali we yu yɛri bɔt wan mɛrɛsin we dɛn kɔl ‘kimotɛrapi’, bɔku tin kin kam na yu maynd. Tide wi go tɔk bɔt wan spɛshal injɛkshɔn we dɛn kin yuz fɔ mɛn dis kayn kansa. Dat na di mɛrɛsin we dɛn kɔl Asparaginase Erwinia Chrysanthemi (Recombinant) we de ɔnda di brand nem Rylaze. Sins dis nem komplikayt likli, wi go jos kol am Rylaze. Dis atikul go tray fɔ ansa yu kwɛstyɔn dɛn bɔt dis mɛrɛsin simpul we.
Wetin na Rylaze (Asparaginase)?
Fɔ tɔk am simpul wan, dis na kemotɛrapi mɛrɛsin we dɛn kin gi fɔ kil kansa sɛl dɛn. Dɛn nɔ kin yuz am fɔ ɔl di kansa dɛn, bɔt dɛn kin yuz am fɔ tu kayn kansa dɛn we gɛt fɔ du wit blɔd. Dɛn tin ya na:
- Akyu Limfoblastik Lukimiya (ALL) .
- Limfoblastik Limfoma
Dis drɔg de wok insay wan we we rili strenj. di kansa sel dεm nid wan amino asid we dεn kכl asparagine fכ gro. di nכmal hεlty sεl dεm na wi bכdi kin mek dis asparagine sεf. Bɔt dɛn lukimiya ɛn limfoma kansa sɛl ya nɔ gɛt da abiliti de. So dis Rylaze drɔg de brok ɛn pwɛl dis asparagine we de na di blɔd. Dɔn di kansa sɛl dɛn kin lɔs di it we dɛn nid ɛn dɛn kin day. di sεl dεm we gεt hεlth kin mek di asparagine we dεn nid, so dεn nכ de du bכku bכku wan.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin fɔ tek mɛrɛsin
Bifo yu bigin dis tritmɛnt, i rili impɔtant fɔ tɛl yu dɔktɔ bɔt yu kɔmplit wɛlbɔdi istri. Mek shɔ se yu tɛl am if yu gɛt ɛni wan pan dɛn tin ya:
| Yu wɛlbɔdi kɔndishɔn | Wetin mek i impɔtant fɔ mek wi no bɔt am? |
|---|---|
| Blɔd disɔda ɔ blɔd klɔt prɔblɛm | Dis mɛrɛsin kin afɛkt di we aw di blɔd de klɔt. |
| Shuga | Di mɛrɛsin kin mek di blɔd shuga go ɔp. |
| If yu gɛt pankrias | Dis mɛrɛsin nɔ kin rili mek pɔsin gɛt pankrias. |
| Liva sik | Di mɛrɛsin kin afɛkt di we aw di liva de wok. |
| Alɛji to wan mɛrɛsin, it, ɔ day | Fɔ asɛs di risk fɔ gɛt alɛji fɔ di mɛrɛsin. |
| If yu gɛt bɛlɛ ɔ yu de tray fɔ gɛt bɛlɛ | Dis rili impɔtant . Di mɛrɛsin kin ambɔg di pikin we nɔ gɛt bɛlɛ. |
| If dɛn de gi di pikin in mama in bɛlɛ | di mεdisin kin pas to di pikin tru in mama in milk. |
Aw a go gi yu dis mɛrɛsin?
Dis nɔto mɛrɛsin we yu kin kɛr go na os. Na di mɛdikal wokman dɛn we tren na ɔspitul ɔ klinik kin gi yu . Bɔku tɛm dɛn kin gi am as injɛkshɔn insay wan mɔsul .
I rili impɔtant fɔ mek yu tek yu mɛrɛsin di de dɛn we dɛn dɔn sɛtul fɔ yu. Nɔ skip dɛn de ya fɔ ɛni rizin. If fɔ sɔm rizin yu nɔ ebul fɔ tek yu mɛrɛsin di de we dɛn dɔn sɛtul fɔ tek, kɔl yu dɔktɔ wantɛm wantɛm ɛn mek dɛn no.
Bikɔs dɛn kin gi dis mɛrɛsin ɔnda di sɔpɔtishɔn fɔ dɔktɔ, chans nɔ de fɔ mek dɛn ‘ɔvados’. Bɔt if yu fil se yu nɔ kin fil fayn afta yu dɔn tek di mɛrɛsin, tɛl di dɔktɔ dɛn wantɛm wantɛm. If ɛnitin apin, yu kin kɔl bak di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital .
Tin dɛn we yu fɔ tink bɔt we yu de du tritmɛnt
Di dɔktɔ we de kia fɔ am ɔltɛm
Di dɔktɔ dɛn go de wach yu sik gud gud wan ɔl di tɛm we yu de tek dis tritmɛnt. Dɛn go ɔda fɔ mek dɛn du blɔd tɛst ɔltɛm . Dɛn go chɛk fɔ si if di mɛrɛsin de wok, if i dɔn afɛkt yu liva, ɛn aw yu blɔd shuga de.
Bεlε εn we i de gi pikin in bεlε
Dis na tin we rili de mɔna wi.
Nɔ gɛt bɛlɛ we yu de tek dis mɛrɛsin. Nɔ gɛt bɛlɛ fɔ at le 3 mɔnt afta yu dɔn stɔp di mɛrɛsin.
Kɔmɔn ɔmon bɔn kɔntrol pils nɔ kin wok fayn wit dis mɛrɛsin. So, mek shɔ se yu tɔk to yu dɔktɔ bɔt ɔda we we nɔ bad fɔ mek yu nɔ bɔn pikin we fayn fɔ yu. Dis mɛrɛsin kin ambɔg di pikin we nɔ bɔn yet bad bad wan.
Dɔn bak, nɔ gi yu pikin in bɛlɛ we yu de tek di mɛrɛsin ɛn fɔ wan wik afta yu dɔn stɔp.
Fɔ no bɔt ɔda mɛrɛsin dɛn
Tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek. Dis inklud mɛrɛsin fɔ ɔda sik dɛn, vaytamɛn, pen kil, ɛbul mɛrɛsin, Ayurveda mɛrɛsin, ɛn sɔpɔtmɛnt. Sɔm mɛrɛsin kin miks wit Rylaze. Fɔ ɛgzampul:
- Kɔtikosterɔyd dɛn (e.g. Prɛdnisolon) .
- Mɛtɔtreksɛt we dɛn kɔl
- Vincristine bin de du am
- Zonisamide we gɛt di sik
- Saytarabin we dɛn kɔl
- Tayrɔyd ɔmon dɛn
Dis list nɔr kɔmplit, so i rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɔltin we yu de tek.
Sayd ɛfɛkt dɛn we kin apin bikɔs ɔf mɛrɛsin
Lɛk ɛni mɛrɛsin, dis kin mek pɔsin gɛt sayd ɛfɛkt. Nɔto ɔlman kin gɛt dɛn. Bɔt i impɔtant fɔ no bɔt dis so dat yu go ebul fɔ du sɔntin kwik kwik wan if ɛni sayn de.
| Sayd ɛfɛkt we pɔsin kin gɛt | Di sayn dɛm wae yu de gɛt |
|---|---|
| Siriɔs sayd ɛfɛkt dɛm we dɛn fɔ ripɔt to di dɔktɔ ɔ di ɔspitul wokman dɛm wantɛm wantɛm | |
| Alɛji we pɔsin kin gɛt | Skin rash, it, swel na di fes, lip, tong, i nɔ izi fɔ blo. |
| Blɔd we nɔ de kɔmɔt fayn | Blak ɔ blɔd stɔl, dak rɛd/brawn urine, vɔmit we tan lɛk kɔfi grɔn, blɔd we de kɔmɔt na di nos/gɔm, rɛd spat na di skin. |
| Blɔd we de klɔt | Chɛst pen, shɔt briz, leg pen, swel, ɔ wam. |
| Pankriaytis we gɛt sik | Big pen na di ɔp pat na di bɛlɛ, i de rayt to di bak, fiva, nɔs, ɛn vɔmit. |
| Liva injuri | di yay dεm εn di skin de yכlכ (jaundice), di urine we de dak yכlכ/brawn, pen na di כp rayt say na di bεlε, i de taya pasmak. |
| Di blɔd shuga we bɔku | Angri we nɔ kin apin, we kin tɔsti pasmak , we pɔsin kin pis bɔku tɛm, we i nɔ kin si fayn, we i kin taya pasmak. |
| Sayd ɛfɛkt dɛn we nɔ kin siriɔs, bɔt dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de | |
| Ed de at | Jɛnɛral ed pen. |
| Fil fɔ it | I nɔ kin want fɔ it igen. |
| Mɔsul dɛn kin pen | Bɔdi de at. |
| Sɔl dɛn na yu mɔt | Smɔl smɔl sɔri dɛn we de insay di mɔt. |
If yu gɛt ɛni ɔda kayn sik we nɔ kɔmɔn we nɔ de na dis list, duya tɛl yu dɔktɔ bɔt dɛn bak.
Mɛsej we dɛn kin kɛr go na os
- Rylaze (Asparaginase) na wan kemotɛrapi injɛkshɔn we dɛn kin yuz fɔ mɛn blɔd kansa we dɛn kɔl lukimiya ɛn limfoma.
- Dɛn kin gi dis mɛrɛsin na ɔspitul ɔ klinik ɔnda dɔktɔ in sɔpɔtishɔn.
- Tɛl yu dɔktɔ bɔt ɔl yu mɛrɛsin ɛn ɔl di ɔda mɛrɛsin dɛn we yu de tek.
- If yu gɛt ɛni siriɔs sayd ɛfɛkt lɛk alɛji, blɔd we nɔ kɔmɔn, ɔ we yu bɛlɛ de at bad bad wan, go to dɔktɔ wantɛm wantɛm.
- Nɔ gɛt bɛlɛ ɔltogɛda we yu de trit yu ɛn fɔ 3 mɔnt afta dat.
- If yu gɛt ɛni kwɛstyɔn ɔ tin we de mɔna yu, nɔ ɛva fred fɔ tɔk to yu dɔktɔ. Dɛn de de fɔ ɛp yu.
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