Na nɔmal tin fɔ mek pɔsin we de fɛt kansa fil fɔ fred smɔl we di dɔktɔ se, "Wi go du stem sɛl transplant." bכt we dεn mεnshכn di wכd "autologous", i min se dεn de du dis tritmεnt yuz yu כwn sεl dεm. Dis na rili fayn we fɔ gi yu bɔdi di pawa fɔ fɛt kansa. Okay, so lɛ wi tɔk bɔt aw dis kɔmplikɛt, wetin i rili de du, ɛn aw dis prɔses de wok insay wan rili simpul, stɛp-by-stɛp we.
Fɔ tɔk am simpul wan, wetin na ɔtologous stem cell transplant?
Imajin dis. Wan vayrɔs dɔn mek yu kɔmpyuta nɔ pwɛl kpatakpata. Naw, fɔ pul dis vayrɔs, yu fɔ `fɔmat` di kɔmpyuta kɔmplit wan. Bɔt wetin yu kin du bifo dat? Yu `bak up` yu most impotant fayl dem to wan seperet ples?
כtכlכg stεm sεl transplant na di sem.
Wetin kin apin ya na dat bifo yu gɛt ay doz kemotɛrapi ɔ redyushɔn tɛrapi fɔ kil di kansa sɛl dɛn, dɛn kin pul sɔm pan yu yon wɛlbɔdi blɔd stem sɛl dɛn na yu bɔdi ɛn kip dɛn sef wan na sayd. dis stεm sεl dεm na di "mama sεl dεm" na wi bon mכro we de mek nyu rεd bכdi sεl dεm, wayt bכdi sεl dεm, εn pletlεt dεm.
We pawaful tritmɛnt dɛn we de agens kansa kil kansa sɛl dɛn, dɛn kin pwɛl wi wɛlbɔdi sɛl dɛn bak, mɔ di bon mɛrɔ. Dɔn, yu yon wɛlbɔdi stem sɛl dɛn we dɛn bin dɔn kip sef, dɛn kin put yu bak insay yu bɔdi. dis sεl dεm de go bak na di bon mכro εn bigin fכ mek di hεlty bכdi sεl dεm we di bכdi nid.
Dis nɔ kin mɛn di kansa ɔltogɛda, bɔt i kin put di kansa insay lɔng tɛm rɛmishɔn, we min se i nɔ gɛt ɛni sayn ɛn dɛn nɔ kin no am pan tɛst.
Dis tritmɛnt kin yuse am mɔ fɔ di kansa kɔndishɔn `Multiple Myeloma`. Dɛn kin yuz am bak fɔ kansa kɔndishɔn lɛk `Hodgkin lymphoma` ɛn `Non-Hodgkin lymphoma` we nɔ de ansa ɔda tritmɛnt dɛn.
Wetin kin apin bifo dis tritmɛnt?
Bifo dɛn du dis kayn pawaful tritmɛnt, dɔktɔ dɛn kin tek tɛm chɛk yu ɔl yu wɛlbɔdi, bikɔs yu bɔdi nid fɔ strɔng fɔ bia wit bɔku kemotɛrapi.
Sɔm tɛst dɛn we dɛn kin du:
- wan `ECG` (Electrocardiogram) tεst we de chεk di at bit.
- wan `Echocardiogram` we de chεk aw di at de wok.
- Wan `CT` (Kɔmpyut Tomografi) skan.
- Wan kɔmplit blɔd kɔnt (CBC).
- Ɔda blɔd tɛst dɛn we de chɛk aw di liva ɛn kidni de wok.
- Bayopsi na tɛst fɔ stɔdi di kansa sɛl dɛn.
Naw, fɔ mek yu nɔ gɛt fɔ kɔntinyu fɔ gɛt nidul, dɔktɔ dɛn kin put wan smɔl tiub we dɛn kɔl `Central Venous Catheter (CVC)` insay wan big vein na yu ɔpa chɛst. Dɔn, ɔltin frɔm we dɛn tek blɔd to we dɛn gi mɛrɛsin, dɛn kin du am izi wan tru dis `CVC`.
Di tri men tin dɛm wae yu fɔ du na di tritmɛnt prɔses
Dis ɔl di prɔses kin sheb to tri men stej dɛm.
1. Fɔ avɛst stem sɛl dɛn
Dis na di say we dɛn kin pul dɛn wɛlbɔdi stem sɛl dɛn we wi bin tɔk bɔt na yu bɔdi. Dɛn kin kɔl dis bak `Apheresis`.
- di vein dεm na yu tu an dεm go kכnekt to wan mashin we de separet sεl dεm.
- Smɔl blɔd kin go insay di mashin frɔm wan an.
- Di mashin de filta di stem sɛl dɛn nɔmɔ frɔm da blɔd de ɛn injɛkt di blɔd we lɛf bak insay di bɔdi tru di ɔda an.
Dis kin tek tri to 4 awa. Insay da tɛm de, yu go nid fɔ de stil, bɔt yu kin rid buk ɔ wach TV.
2. Fɔ kɔndishɔn di bɔdi
Dis na di pat we at pas ɔl. Dis na di tɛm we yu go gɛt ay doz kemotɛrapi ɛn sɔntɛm redyushɔn tɛrapi fɔ kil di kansa sɛl dɛn. Dis kin tek sɔm dez. Yu mɛdikal tim go de wit yu fɔ manej ɛni sayd ɛfɛkt we go apin insay dis tɛm.
| Posisibul sayd effekt dɛm fɔ kondishɔn tritmɛnt | |
|---|---|
| Sɔt tɛm sayd ɛfɛkt dɛn | Di sayd ɛfɛkt dɛn we kin apin fɔ lɔng tɛm |
| Anemia (lɔ blɔd kɔnt), nɔs ɛn vɔmit, dayarɛa, taya pasmak, nɔ kin want fɔ it, yu mɔt kin gɛt sɔl, yu ia kin lɔs. | Ɔstioporosis, katarakt, we yu nɔ ebul fɔ gɛt bɛlɛ kwik kwik wan, we yu nɔ kin ebul fɔ bɔn pikin, we kin mek yu gɛt sɛkɔn kansa. |
3. Sεl transplant/infushכn
Dis tan lɛk fɔ gi sɔl sɔl ɔ blɔd pak. afta dat dεn kin put yu כwn stεm sεl dεm we dεn kכlekt εn stכr sef wan bak insay yu bכdi tru IV כ CVC. Insay dis tɛm, di mɛdikal tim go de wach yu ɔltɛm fɔ si if yu gɛt sɔm sayn dɛn lɛk fiva ɛn kol.
Wetin kin apin afta dɛn dɔn trit am? Lɛ wi lan bɔt di tɛm we pɔsin kin wɛl
Afta yu dɔn trit yu, yu bɔdi go bigin fɔ wɛl smɔl smɔl.
- Engraftment: Di nyu stεm sεl dεm we dεn infuz de travul tru di bכdi, setul insay di bon mכro, εn bigin fכ mek nyu hεlty bכdi sεl dεm. dis prכsεs dεn kכl am `Engraftment`.
- Risk fɔ gɛt infɛkshɔn: Afta di engraftmɛnt, yu risk fɔ gɛt infɛkshɔn kin rili bɔku te yu wayt blɔd sɛl kɔnt kam bak to nɔmal. So, i rili impɔtant fɔ protɛkt yusɛf frɔm infɛkshɔn insay dis tɛm.
- Tɛm fɔ wɛl: I kin tek ɛnisay frɔm 3 to 12 mɔnt fɔ mek yu imyun sistɛm wɛl ful wan. So nɔ rɔsh am. Na sɔm tin dɛn we go ɛp yu:
- Gɛt bɔku rɛst: Sɔm dez yu kin fil taya bad bad wan. Tek sɔm rɛst da tɛm de.
- It tin dɛn we gɛt fayn fayn tin dɛn fɔ it: If yu it tin dɛn we gɛt bɔku prɔtin, dat kin ɛp fɔ mek yu bɔdi bil bak.
- Ɛksesaiz: As yu fil se yu gɛt trɛnk so, bigin fɔ du simpul ɛgzampul dɛn lɛk fɔ waka. Bɔt mek shɔ se yu tɔk to yu dɔktɔ bifo yu bigin ɛni nyu tin.
- Ɔpdet yu vaysin dɛm: Afta dis tritmɛnt, di protɛkshɔn we yu bin gɛt frɔm di vaysin dɛm we yu bin gɛt we yu bin smɔl go lɔs. So, yu dɔktɔ go tɛl yu ustɛm fɔ gɛt di vaysin bak ɛn us vaysin fɔ gɛt.
Wetin na di difrɛns bitwin Autologous ɛn Allogeneic transplant?
di men difrεns bitwin dεn tu na di say we di sεl dεm de kכmכt. Fɔ ɔndastand dis simpul wan, luk di tebul we de dɔŋ ya.
| Di Tayp fɔ Transplant | Udat dɛn kin gɛt stem sɛl frɔm? |
|---|---|
| Ɔtɔlɔg | Frɔm yusɛf. Dɛn kin gɛda yu yon sɛl dɛn bifo dɛn trit yu kansa. |
| Allojenik we dɛn kɔl | Frɔm pɔsin we gɛt wɛlbɔdi. Bɔku tɛm, dɛn kin gɛt di tisu frɔm pɔsin we de na di famili ɔ ɔda pɔsin we fit am. |
Ustɛm fɔ go to dɔktɔ wantɛm wantɛm
Ivin if yu kin gɛt dɔktɔ chɛk-ap ɔltɛm afta yu dɔn gɛt tritmɛnt, i impɔtant fɔ tɛl yu mɛdikal tim wantɛm wantɛm if yu gɛt ɛni sayn fɔ se yu gɛt prɔblɛm. Wach fɔ dɛn sayn ya:
- Fiva
- Fɔ fil kol ɛn shek shek
- I nɔ izi fɔ blo (Dyspnea) .
- Fɔ kɔf, sniz, ɔ fɔ rɔn na yu nos
- Yu kin pis ɔltɛm ɔ yu kin fil pen we yu de pis (Dysuria) .
- Rash na di skin
- Diziz we pɔsin kin gɛt
Mɛsej we dɛn kin kɛr go na os
- Wan ɔtolɔg stem sɛl transplant involv fɔ gɛda yu yon wɛlbɔdi stem sɛl dɛn bifo yu gɛt kansa tritmɛnt ɛn afta dat yu fɔ gi dɛn bak na yu bɔdi afta yu dɔn trit yu.
- dis na mכlti stεp prכsεs: sεl kכlekshכn, hכy dכz kכndishכn, εn sεl riintrodכks.
- Di men risk afta tritmɛnt na fɔ gɛt siriɔs infɛkshɔn, so i rili impɔtant fɔ protɛkt yusɛf frɔm infɛkshɔn.
- I kin tek sɔm mɔnt fɔ mek di bɔdi wɛl, so du gud to yusɛf ɛn tek kia ɔf yu rɛst ɛn it.
- Ɔl di sikman difrɛn, so ɔltɛm tɔk opin wan wit yu dɔktɔ we de trit yu fɔ no if dis tritmɛnt fayn fɔ yu, di sakrifays we i go gɛt, ɛn di prɔblɛm dɛn we i go gɛt.
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