yu go don yehri boht "anemia" o "anemia" no? Fɔ tɔk am simpul wan, na we wi bɔdi nɔ de mek inof rɛd blɔd sɛl ɔ di rɛd blɔd sɛl dɛn we wi gɛt nɔ de wok fayn. Rɛd blɔd sɛl dɛn na di men tin dɛn we de kɛr ɔksijɛn ɔlsay na wi bɔdi. So we dɛn smɔl, wi kin fil taya ɛn taya ɔltɛm. Dɛn rɛd blɔd sɛl ya kin kɔmɔt na di bon mɛro, we na wan saf ɛn spɔnj tisu insay wi bon dɛn. Daymɔnd-Blakfan Anemia (DBA) na spɛshal kayn anemia we kin apin we di bon mɛro nɔ ebul fɔ mek inof rɛd blɔd sɛl.
Wetin kin mek pɔsin gɛt Daymɔnd-Blakfan Anemia (DBA)?
Daymɔnd-Blakfan Anemia, we sɔm pipul dɛn kin kɔl ``acquired pure red cell aplasia'', na in dɔktɔ dɛn kin no bifo pikin ol wan ia. Di men tin we kin mek dis apin na we di jin dɛn we de bil wi bɔdi kin chenj ɔ we kin chenj.
Mɛmba se sɔntɛnde, dis prɔblɛm we de na di jɛnɛtiks kin kɔmɔt frɔm di mama ɔ di papa. Bɔt nɔto so i kin bi ɔltɛm. Sɔm pikin dɛn jin kin chenj bak fɔ dɛnsɛf fɔ natin. di mכtalman in pikin dεm we gεt DBA gεt dis kכndyushכn biכs fכ wan nyu jεnεtik mכtεshכn. So, as mama ɛn papa, nid nɔ de fɔ wɔri bɔt dis we nɔ impɔtant. Pan ɔl we dɛn dɔn fɛn wan patikyula jɛnɛtik kɔz fɔ lɛk af pan di wan dɛn we gɛt DBA, fɔ sɔm pipul dɛn, dɛn nɔ dɔn fɛn wan patikyula kɔz fɔ dis sik yet.
Wetin na di sayn dɛm fɔ DBA?
Pikin dɛm we gɛt DBA kin gɛt bɔku pan di kɔmɔn sayn dɛm bak fɔ ɔda kayn anemia. Dat na,
- Fɔ taya ɔltɛm
- Pale skin
- Fɔ fil se yu wik
Apat frɔm dɛn kɔmɔn tin ya, sɔm pikin dɛn we dɛn bɔn wit DBA kin gɛt sɔm patikyula tin dɛn we de na dɛn fes ɛn bɔdi. Lɛ wi tek wan luk pan wetin dɛn bi.
| Di pat na di bɔdi | Di tin dɛn we pɔsin kin si |
|---|---|
| Ed | Fɔ gɛt ed we smɔl pas di nɔmal ed. |
| Fes | distans bitwin di yay dεm we de go כp εn di nos we flat. |
| Yes | Tu smɔl yes dɛn we dɛn kin sɛt dɔŋ pas aw i kin bi. |
| Jɔ | Fɔ gɛt smɔl smɔl jaw we de dɔŋ. |
| Nɛk | Wan shɔt nɛk we gɛt wɛb. |
| Sholda dɛn | Smɔl smɔl smɔl sholda dɛn. |
| An dɛn | Thumbs we gɛt shep we nɔ kɔmɔn. |
| Mɔt | Fɔ gɛt cleft palata ɔ lip. |
Apat frɔm dat, DBA kin mek yu gɛt prɔblɛm wit yu kidni , at pwɛl , ɛn yu yay prɔblɛm lɛk katarakt ɛn glaukoma . Bɔy pikin dɛn kin gɛt wan prɔblɛm bak we dɛn bɔn we dɛn kɔl hypospadias, we na we di say we dɛn opin fɔ urine nɔ de na di tip na di penis.
Aw fɔ no dis sik kɔrɛkt wan?
Yu dɔktɔ kin du sɔm tɛst fɔ no if yu pikin gɛt DBA. Pikin dεm we gεt DBA gεt lכw rεd blכd sεl kכnt, bכt nכmal wayt blכd sεl εn pletlεt kכnt.
Di tin we impɔtant pas ɔl na fɔ nɔ panik we yu si dɛn sik ya, bɔt fɔ go to dɔktɔ we sabi du di wok kwik kwik wan. I go du di tɛst dɛn we yu nid ɛn gi yu di infɔmeshɔn we kɔrɛkt pas ɔl.
Dis na sɔm pan di men tɛst dɛn we di dɔktɔ kin du.
| Tɛst | Wetin i de luk fɔ? |
|---|---|
| Kɔmplit Blɔd Kɔnt (CBC) . | Dɛn kin mɛzhɔ bɔku tin dɛn na di blɔd, lɛk di nɔmba fɔ di rɛd blɔd sɛl dɛn, di wayt blɔd sɛl dɛn, di pletlɛt dɛn, di prɔtin we gɛt ɔksijɛn we gɛt ɛmoglobin, ɛn di volyum fɔ di rɛd blɔd sɛl dɛn (hematocrit) . |
| rεtikulכsayt kכnt | Dis kin mɛzhɔ di nɔmba fɔ di rɛd blɔd sɛl dɛn we nɔ machɔ ɔ we jɔs dɔn fɔm. dis kin sho if di bon mכro de prodyuz rεd sεl dεm fayn fayn wan. |
| Chek eADA lɛvɛl | כlmost 80% pan di pipul dεm we gεt DBA gεt εlevεt lεvεl fכ wan εnzym we dεn kכ l εrythrocyte adenosine deaminase (eADA) . Dis na wetin dis tɛst de luk fɔ. |
| di εmoglobin lεvεl dεm na di pikin | Dis na di kayn ɛmoglobin we di pikin dɛn gɛt na di bɛlɛ. I fɔ go dɔŋ afta dɛn bɔn am. Bɔt pikin dɛn we gɛt DBA kin stil gɛt ay levul as dɛn de ol. |
| Bon mכro aspirashכn εn bayopsi | dεn kin tek sכm sכm sεl dεm εn wata frכm di bon mכro we dεn de yuz nidul εn tεst dεm. Pikin dεm we gεt DBA gεt bכku bכku hεlty rεd bכdi sεl dεm na dεn bon mכro. |
| Tɛst dɛn we dɛn kin du fɔ tɛst dɛn jɛnɛtiks | Dis de tεst fכ jin dεm we riliyt to DBA כ כda anemia we dεn gεt frכm mama εn papa. |
Us ɔda kɔmplikɛshɔn dɛn kin apin bikɔs ɔf DBA?
Pipul wae gɛt DBA kin gɛt sɔm sik ɛn kɔndishɔn smɔl. Dɛn tin ya na kansa na di blɔd ɛn bon mɛro (acute myeloid leukemia), bon kansa (osteosarcoma), ɛn ɔda sik dɛn we di bon mɛro nɔ kin ebul fɔ mek wɛlbɔdi blɔd sɛl (myelodysplastic syndrome). Bɔt nɔ wɔri bɔt dis. Dɔktɔ dɛn de wach dis ɔltɛm, so yu kin tek di mɛrɛsin we yu nid di rayt tɛm.
Wetin na di tritmɛnt dɛm fɔ dis?
Dis na di pat we impɔtant pas ɔl ɛn we de kɔrej wi. Pikin dɛm we dɛn no se gɛt DBA kin liv lɔng, sakrifays layf wit mɛrɛsin. Sɔm pikin dɛn kin go na kɔmplit rɛmishɔn, we min se di sayn dɛn kin dɔn fɔ sɔm tɛm.
Di tu men tritmɛnt dɛn we dɛn kin yuz na kɔtikosterɔyd mɛrɛsin ɛn blɔd transfyushɔn.
- kכtikostεroyd dεm: Drug dεm lεk `(Prednisone)` de mek di bon mכro wok εn εp am fכ mek mכr rεd bכdi sεl dεm.
- Blɔd transfyushɔn: Dis na fayn tin fɔ du if stɛroyd mɛrɛsin nɔ wok, ɔ if di anemia rili bad. Dis min se dɛn fɔ gi di pikin blɔd ɔ rɛd blɔd sɛl frɔm pɔsin we gɛt wɛlbɔdi.
- Bon mכro/stεm sεl transplant: Dis na di כnli kכretiv tritmεnt fכ DBA. Bɔt, i kin mek pɔsin gɛt prɔblɛm smɔl. Dɔn bak, sɔntɛnde i nɔ kin izi fɔ fɛn pɔsin we go gi di mɔni we go gri wit am.
I impɔtant fɔ tɔk to yu dɔktɔ klia wan bɔt ɔl dɛn tritmɛnt ya, di gud ɛn bad tin dɛn we dɛn kin du, ɛn pik wetin bɛtɛ fɔ yu pikin.
Mɛsej we dɛn kin kɛr go na os
- Daymɔnd-Blakfan Anemia (DBA) na wan jɛnɛtik kɔndishɔn we nɔ kin apin to pikin dɛn usay di bon mɛro nɔ kin ebul fɔ mek inof rɛd blɔd sɛl.
- Along wit di kɔmɔn simptom dɛm lɛk fɔ taya ɔltɛm ɛn fɔ pale, dis sik kin mek sɔm patikyula ɔda tin dɛm bak na di fes ɛn bɔdi.
- Dɔktɔ kin no dis sik kɔrɛkt wan bay we i de du blɔd tɛst ɛn ɛgzamin in bon mɛro.
- Tritmɛnt lɛk sterɔyd mɛrɛsin ɛn blɔd transfyushɔn kin ɛp pikin dɛn fɔ liv lɔng, wɛlbɔdi layf. Bɔn mɛrɔ transplant na di wangren tritmɛnt we go mɛn am.
- If yu gɛt ivin smɔl saspek se yu pikin gɛt dɛn sik ya, nɔ panik ɛn go to dɔktɔ we de mɛn pikin dɛn wantɛm wantɛm. Fɔ no di sik kwik kwik wan ɛn fɔ trit am rili impɔtant.
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